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Elsevier

Books in Life sciences

  • Life Sciences and Space Research

    Proceedings of The Open Meetings of The Working Group on Space Biology of The Twentieth Plenary Meeting of COSPAR, Tel Aviv, Israel, 7-18 June 1977
    • 1st Edition
    • R. Holmquist + 1 more
    • English
    Cospar Life Sciences and Space Research, Volume XVI covers the proceedings of the Open Meetings of the Working Group on Space Biology of the 20th Plenary Meeting of COSPAR, held in Tel Aviv, Israel, on June 7-18, 1977. The book focuses on the developments in space explorations; approaches for the creation of extraterrestrial intelligence; and biochemical mechanism of the visual-light-flash phenomena. The selection first discusses the Viking Lander biology experiments on Mars. The experiments returned detailed picture of the Martian soil surface chemistry. The text also takes a look at a preliminary search for narrowband signals at microwave frequencies; observational program options and system requirements for the search of extraterrestrial intelligence; and public health considerations related to a Mars surface sample return mission. The book reviews planetary protection guidelines for outer planet missions, including Viking clean room technology, efficacy of clean room assembly, and Jupiter Orbiter Probe PP appraisal. The text also focuses on the effects of temperature, salinity, and other factors on the growth and formation of UV-absorbing substances by the fungus aspergillus; effects of gravitational and magnetic fields on transplanted neuroblastoma vascularity; and the roles of body mass and gravity in identifying the energy requirements of homoiotherms. The selection is a dependable reference for readers interested in space research.

  • Neurotrauma

    Treatment, Rehabilitation, and Related Issues
    • 1st Edition
    • Michael E. Miner + 1 more
    • English
    Neurotrauma features the papers presented at the Second Houston Conference on Neurotrauma in Texas held in May 1985. These papers cover discussions on patients who have both brain and spinal cord injuries and acute care treatment and investigations of brain injury, as well as rehabilitation strategies and approaches. This second edition is organized into four parts. The first part deals with the treatment of less-than-severe head injury, barbiturate-induced coma, closed head injuries, and severely brain-injured patients. The second part focuses on the evaluation of physiological and anatomical recovery of brain injury patients, while the third part discusses the management of patients with combined head and spinal cord injury. The final part focuses on rehabilitation issues that include nonpharmacological management, the impact of traumatic brain injury on sexuality, and ethical aspects of lifesaving therapeutic strategies. This book may be of interest to persons dealing with studies on the treatment of brain and spinal cord injuries.

  • Andreas Vesalius Bruxellensis

    The Bloodletting Letter of 1539: An Annotated Translation and Study of the Evolution of Vesalius's Scientific Development
    • 1st Edition
    • John B. De C. M. Saunders + 1 more
    • English
    Andreas Vesalius Bruxellensis: The Bloodletting Letter of 1539 provides an insight into the knowledge of anatomy in that period. This book presents an overview of the development of the practice of venesection. This text discusses the discovery of the venous valves in the human body. Vesalius points out in this text the anatomical basis for the employment of phlebotomy. This book is liberally annotated to guide the readers. Medical historians will find this book extremely useful.

  • Introduction to Animal Physiology and Physiological Genetics

    International Series of Monographs in Pure and Applied Biology
    • 1st Edition
    • E. M. Pantelouris
    • G. A. Kerkut
    • English
    Introduction to Animal Physiology and Physiological Genetics, deals with topics on physiological measurement, comparisons, and analysis of the role of genotypes. This book emphasizes two aspects — the changes of physiological patterns in the course of development and the wide variation that can be found within a species. The text discusses the response mechanisms of living organisms from nerve impulses, chemical sense, muscle reaction, and includes some studies made on brain function. The effects of nutrition and energy such as the intake of food, water, oxygen, and the calculation of basic metabolic rates are explained. The book then discusses the role of the internal environment and that of the interstitial body fluid in the higher animals. The discussion covers blood circulation, cardiac cycle, and a special section on the function of the heartbeat in the spider Limulus showing that stimulation of the abdominal ganglia increases the heartbeats. The text also considers significant concepts of physiological genetics, and then explains asexual and sexual reproduction, the sex hormones of invertebrates, and the use of stimulants for animal production. The physiological differences between species are examined, but more particularly on the reservoir of genetic diversity, where differences abound between families and offspring. One research made in molecular biology concludes that genes are responsible for regulating the amino acid sequence of proteins. Molecular biologists, general biologists, zoologists, and microbiologists will find the articles in this collection invaluable.

  • Aminopyridines and Similarly Acting Drugs: Effects on Nerves, Muscles and Synapses

    Proceedings of a IUPHAR Satellite Symposium in Conjunction with the 8th International Congress of Pharmacology, Paris, France, July 27-29, 1981
    • 1st Edition
    • P. Lechat + 2 more
    • English
    Aminopyridines and Similarly Acting Drugs: Effects on Nerves, Muscles and Synapses presents the proceedings of a IUPHAR Satellite Symposium in conjunction with the eighth International Congress of Pharmacology held in Paris, France on July 27-29, 1981. The book contains papers on the effects of aminopyridines on ionic currents in excitable membranes; the effects of aminopyridines on synaptic transmission; and the effects of aminopyridines on the release of chemical transmitters. The text also presents papers on some differences in the blockade of potassium permeabilities by apamin and the aminopyridines; the miscellaneous actions of aminopyridines and related compounds; and the effects of aminopyridines on the skeletal, smooth and cardiac muscle. The clinical applications of aminopyridines and further miscellaneous actions of aminopyridines and related compounds are also considered.

  • Essays in Toxicology

    Volume 1
    • 1st Edition
    • Frank R. Blood
    • English
    Essays in Toxicology, Volume 1 covers essays in toxicology and related topics. The book presents essays on the use of poisons as tools in studying the nervous system as well as teratology. The text also includes essays on the significance of methemoglobinemia in toxicology and lead poisoning. Biochemists, plant and animal physiologists, pharmacologists, pathologists, microbiologists, entomologists, food technologist, and people involved in forensic medicine and industrial medicine.

  • General Botany

    • 1st Edition
    • Wilhelm Nultsch
    • English
    General Botany covers certain aspects of general botany, such as morphology, anatomy, and histology. The book discusses the molecular constitution of plants; the structural constitution of the protoplasm, the cell, and the cytoplasm; and the differentiation of the cell. The text also describes the types of organization in plants; the internal and external structure of the stem, the leaf, and the root; and water and salt balance, with regard to the translocation of materials. The energy procurement and the synthetic processes in autotrophic plants; the respiration and energy transformations; and nitrogen metabolism are also considered. The book further tackles heterotrophy; reproduction; heredity; development; and the movement of plants. Botanists, cytologists, plant physiologists, and students taking related courses will find the text invaluable.

  • Presynaptic Receptors and Neuronal Transporters

    Official Satellite Symposium to the IUPHAR 1990 Congress Held in Rouen, France, on 26–29 June 1990
    • 1st Edition
    • S.Z. Langer + 2 more
    • English
    Advances in the Biosciences, Volume 82: Presynaptic Receptors and Neuronal Transporters documents the proceedings of the Official Satellite Symposium to the IUPHAR 1990 Congress held in Rouen, France on June 26-29, 1990. The first part of this book deals with the extensive and still increasing list of presynaptic release-modulating auto and heteroreceptors, emphasizing the various subtypes of presynaptic receptors that are characterized by functional studies, both in vitro and in vivo, using a number of experimental approaches. The next chapters are devoted to the molecular pharmacology of presynaptic receptors, of which can interfere with G proteins and modify the activity of adenylate cyclase, guanylate cyclase, or protein kinase C. The purification and molecular biology of transporter systems, including cloning and sequencing of the neuronal sodium-ion coupled GABA transporter are also discussed. This compilation concludes with insights on the function of presynaptic receptors and neuronal transporters both in the periphery and in the CNS, as well as their ubiquitous locations and physiological roles. This publication is a good reference for students and individuals researching on the presynaptic autoreceptors and neurotransmitters.

  • Recent Developments in Ruminant Nutrition

    • 1st Edition
    • W Haresign + 1 more
    • English
    Recent Developments in Ruminant Nutrition presents papers that discuss the advancement of the different areas of ruminant nutrition. The book is comprised of 20 chapters that cover topics, such as reproduction, diet, and nutrition. The coverage of the text includes growth stimulation in ruminants; protein quantity and quality for the U.K. dairy cow; and complete-diet feeding of dairy cows. The book also covers rumen fermentation related topics, such as influence of nitrogen and carbohydrate inputs on rumen fermentation; aspects of the biochemistry of rumen fermentation and their implication in ruminant productivity; and manipulation of rumen fermentation. The text will be of great use to researchers and professionals in the animal husbandry industry.

  • Recent Developments in Pig Nutrition

    • 1st Edition
    • D J A Cole + 1 more
    • English
    Recent Developments in Pig Nutrition shows the updates in the nutrition and the evaluation of energy needs in raising and breeding pigs. The book covers the energy requirement of pigs; the effects of climatic variables on the nutrition and energy of pigs; and the prediction of energy content in pig feeds. The availability and importance of proteins and amino acids in pig feeds are also discussed. The text also explains the importance of vitamins and minerals in the diet of pigs; the nutritional needs of the different sexes of pigs and piglets; and the processing and evaluation of cereals for pig diets. The monograph is recommended for those in piggery business, who want to know more about the importance of pig nutrition and be updated with the different findings in the field. The book will also be good for animal nutritionists who concern themselves with pig feeds and for veterinarians who specialize in pigs.

  • Plant Pests and their Control

    • 1st Edition
    • Peter G. Fenemore
    • English
    Plant Pests and their Control, Revised Edition discusses the concepts involved in pest management, along with its application, constraints, and opportunities. This book is comprised of 13 chapters that cover topics relevant in understanding the basis and practice of pest management. The first six chapters deal with the various aspects of entomology. These chapters cover the importance of insects; the physiological properties of insects; and reproduction and life cycle. The next chapter covers the non-insect pests. Chapter 8 discusses the relationship between insects and plants, while Chapter 9 covers the mortality factors of insect, such as predators, parasites, and pathogens. The next chapter presents the ecological background of pest control. The remaining three chapters discuss pest management itself. This text will be of great use to agriculturists, horticulturalists, and pest control professionals. Household owners dealing with residential pest infestation will also find this book a great source of information.

  • Elements of Marine Ecology

    An Introductory Course
    • 3rd Edition
    • R. V. Tait
    • English
    Elements of Marine Ecology: An Introductory Course, Third Edition provides a concise discussion on the general field of marine ecology. The book is comprised of nine chapters that cover the structures and functions of marine ecosystems. The text first covers the oceans, including its extent and depths, currents, and biological features. Chapter 2 deals with marine planktons. Next, the book discusses the measuring and sampling techniques used at sea to obtain information of interest. The fourth chapter tackles the parameters of marine environment, while the fifth chapter deals with organic production in the sea. The text also covers the two extremities of the sea that are the seashore and the sea bottom. The last chapter discusses some concerns in sea fisheries. The book will be of great use to researchers and professionals whose work involves marine flora and fauna.

  • The Peripheral Blood Film

    • 2nd Edition
    • Trevor A. Harper
    • English
    The Peripheral Blood Film, Second Edition presents the various concepts of the origin, development, and functions of blood cells. This book serves as a practical guide to the different types of film appearances that may be encountered in the routine examination of peripheral blood films. Organized into 14 chapters, this edition begins with an overview of the composition of plasma, which consists mainly of water and many organic and inorganic compounds. This text then discusses the process of obtaining capillary blood and explains how the thin blood film is prepared in the laboratory. Other chapters present the alphabetical listing of diseases, disorders, and abnormal film appearances for easier reference. This book discusses as well the characteristics of normal peripheral blood cells. The final chapter deals with the characteristics of blood film in various types of diseases, including Cushing's disease, Addison's disease, cirrhosis of the liver, and collagen disorders. This book is a valuable resource for hematologists and pathologists.

  • Physiology and Toxicology of Male Reproduction

    • 1st Edition
    • James C. Lamb + 1 more
    • English
    Physiology and Toxicology of Male Reproduction is a collection of papers that deals with general reproductive biology and specific aspects of reproductive toxicology, pertaining to the male sex. Some papers discuss testicular organization, reproductive toxicity testing systems, and germ-cell genetic toxicology. The use of in vitro systems by investigators to dissect the male reproductive toxicants can lead to a more scientific approach toward hazard assessment and the development of safer drugs and chemicals. Other papers explain the fundamental reproductive biology of the testis, the neuroendocrine system, the epididymis and accessory sex organs, and spermatozoal evaluation. Toxicological aspects cover the toxicological evaluation of the complete reproductive system, testicular morphology, sperm assessment, and germ-cell mutagenesis. One paper describes alternative methods in toxicology—by using new in vitro systems that should reduce or eliminate the need for tests conducted on animals. In vitro methodology embraces other systems such as from subcellular fractions to isolated intact organs. In relation to target-organ toxicity, the researcher can focus using primary cell cultures. This collection will prove helpful to toxicologists, graduate students and researchers in biology, particularly in male reproductive toxicology and fertility testing.

  • The Saccharine Disease

    Conditions Caused by the Taking of Refined Carbohydrates, Such as Sugar and White Flour
    • 1st Edition
    • T. L. Cleave
    • English
    The Saccharine Disease, Conditions Caused by the Taking of Refined Carbohydrates, such as Sugar and White Flour contends that the causation of these conditions has been obscured through confusing distinctions between unnatural, refined carbohydrates and that of natural, unrefined carbohydrates like fruits and whole meal flour. The author notes that all the foregoing conditions are really the manifestations of a single master-disease—that many of the major diseases of modern societies are caused by consuming unreasonable amounts of refined carbohydrate foods. The author discusses that in the short time that man has changed his diet, evolutionary adaptation is left behind. He gives two rules to prevent and arrest all saccharine disease manifestations: Do not eat any food unless you definitely want it, and avoid eating white flour or white sugar. These two rules will prevent gastric or duodenal ulcer, diabetes, coronary disease, constipation, complications of varicose veins, hemorrhoids, E. coli infections, obesity, and some skin conditions, As a retired Surgeon-General of the Royal Navy, the author bases his assumptions on evolutionary, epidemiological, and other scientific or historical work. This book can give insights to dieticians, food researchers, nutritionists, people on diet, and general medicine practioners.

  • Mycobacteria

    Institute of Medical Laboratory Sciences Monographs
    • 1st Edition
    • Maureen V. Chadwick
    • F. J. Baker
    • English
    Mycobacteria covers some aspects of mycobacterial identification. The book starts by describing a historical review of tuberculosis, including topics about searching for its causes and cure and about the use of chemotherapy for treating tuberculosis. The text describes the different species of Mycobacteriaceae, including Mycobacterium tuberculosis, M. africanum, M. bovis, M. microti, and M. ulcerans. Safety precautions in pathology laboratories; the preparation of good culture media and sensitivity test media; and the treatment of specimens are also considered. The book further tackles sensitivity testing of Mycobacteria using the resistance ratio method, the proportional method and the absolute concentration method, and methods of identifying mycobacteria. The text also describes assay methods for anti-tuberculosis drugs. Pathologists, medical technologists, and other people working in pathology laboratories will find the book useful.

  • Food Legislative System of the UK

    • 1st Edition
    • Stephen J. Fallows
    • English
    Food Legislative System of the UK discusses the principles underlying the country's food laws, the historical context of today's food legislation, and the process for amendments in legislation. The book also reviews the influences on the system such as those arising from interest groups, the changing diet, and health environment. In addressing the Food Legislative System of the United Kingdom, the book tackles various examples of food legislation and numerous food- related advisory bodies. Industry, consumer, or enforcement pressures can initiate changes and modifications of laws. Once ministers are convinced that a prima-facie case exists for amending food legislation, they will seek advice from various authorities; make a draft, and present it for full parliamentary procedure. For example, the "Food and Environment Bill" has passed through Parliament by ministers representing the Ministry of Agriculture, Fisheries and Food, while the "Food Bill" has gone through another route with the chief legal officers and company. The book emphasizes the mechanisms through which change is achieved, as well as the points when opportunities exist for interest groups to make their views known to the decision makers. The book can be helpful for food lobbyists, consumer food groups, nutritionists, political scientists, and heads of food and welfare organizations.

  • Forensic Toxicology

    Proceedings of a Symposium Held at the Chemical Defence Establishment, Porton Down, 29-30 June 1972
    • 1st Edition
    • Bryan Ballantyne
    • English
    Forensic Toxicology presents the legal and medical aspects of the detrimental effects of chemicals on humans. This book discusses the immediate and long-term consequences of accident or deliberate poisoning, the detection of such poisoning, and the interpretation of the possible importance of demonstrating exogenous substances in biological fluids and tissues. Organized into 14 chapters, this compilation of papers begins with an overview of the fundamental procedure and interpretation in forensic toxicology. This text then examines the ways in which enzymes may be used in the analysis of drugs. Other chapters consider the equipment and reagents required in the rapid tests for drugs in urine. This book presents as well barbiturate poisoning from the viewpoint of the forensic pathologist performing the post mortem over the cause of death. The final chapter deals with further advances in forensic toxicology. This book is a valuable resource for general practitioners, forensic toxicologists, forensic pathologists, and police officers.

  • Recent Developments in Poultry Nutrition

    • 1st Edition
    • D.J.A. Cole + 1 more
    • English
    Recent Developments in Poultry Nutrition is a collection of studies that cover important developments in poultry nutrition. The book presents 23 papers that deal with the various areas of concerns in poultry nutrition. The coverage of the text includes materials that deal with poultry diet, such as metabolizable energy evaluation of poultry diets; the impact of declaration of the metabolizable energy value of poultry feeds; and the influence of fiber on digestibility of poultry feeds. The book also deals with egg production issues, including the influence of nutritional factors on hatchability; eggshell formation and quality; and dietary phosphorus for laying hens. The text will be of great use to researchers and professionals in the poultry industry. Consumers will also find this book interesting since it discusses topics that can directly affect them.

  • Routes of Drug Administration

    Topics in Pharmacy
    • 1st Edition
    • A. T. Florence + 1 more
    • English
    Routes of Drug Administration covers topics about parenteral and enteral routes of drug administration. The book discusses the anatomy and physiology of administration sites; the formulation and design of delivery systems; and other relevant aspects of biopharmaceutics. The text describes pulmonary delivery, nasal, buccal, and transdermal routes of administration for systemic delivery, as well as a number of systems for more localized therapy with antibiotics. Innovative methods of antibiotic administration, such as continuous and intermittent infusion, endotracheal installation, aerosol delivery, antibiotic-impregnat... catheters, antibiotic-containin... bone cement, and beads, are also considered. Senior undergraduate and postgraduate students in pharmacy, medicine, nursing and allied health sciences and practitioners in these fields, as well as other professionals concerned with the preparation and administration of medicines and the monitoring of drug therapy will find the book useful.

  • Theory and Practice of Blood Flow Measurement

    • 1st Edition
    • John P. Woodcock
    • English
    Theory and Practice of Blood Flow Measurement presents the methods for determining the metrics of blood flow in the major vessels. This book is organized into two sections encompassing 16 chapters that discuss the theories behind the different techniques of flow measurement and the performance of flowmeters and their practical application to determining blood flow volume in the tissues and organs. Considerable chapters are devoted to various methods of blood measurement, including dilution, transport, and thermal techniques, as well as the effect of catheter sampling on the shape of indicator dilution curves. Other chapters are concerned with the possible errors in the application of indicator dilution techniques and the types of dilution indicator, and measurement of indicator concentration. A chapter is devoted to the advantages and disadvantages of thermistor flowmeter. The last chapter focuses on the design of a thermal dilution catheter. The book can provide useful information to physicists, bioengineers, surgeons, students, and researchers.

  • A Synopsis of Infectious and Tropical Diseases

    • 3rd Edition
    • A. W. Woodruff + 1 more
    • English
    A Synopsis of Infectious and Tropical Diseases provides a summary of information on the diagnosis and management of infectious and tropical diseases. It contains essential information required by general practitioners, specialists, medical students and graduates preparing for higher examinations, the nursing profession, and health workers in the proper management of infective and tropical diseases. This book is organized into nine chapters that describe the signs and symptoms, clinical forms and manifestations, incubation period, stages of invasion, mode of transmission, epidemiology, and treatment of different tropical and infectious diseases such as those caused by viruses, protozoans, and metazoan parasites. These diseases include herpesvirus infections, blackwater fever, and trematode or fluke infections. This book will be of interest to travelers and people in the medical profession.

  • Recent Developments in Ruminant Nutrition – 2

    • 1st Edition
    • W. Haresign + 1 more
    • English
    Recent Developments in Ruminant Nutrition – 2 presents papers that discuss the advances in the different areas of ruminant nutrition. The book is comprised of 22 chapters that discuss topics such as milk production, health, and nutrition. The coverage of the text includes meeting the nutrient requirements of beef cattle in forage-based systems of production; nutrient requirements of intensively reared beef cattle; and feeding for high margins in dairy cows. The book also tackles issues concerning milk production such as photoperiodic influences on milk production in dairy cows; manipulation of milk yield with growth hormone; and the influence of level and pattern of concentrate input on milk output. The text will be of great use to researchers and professionals in the animal husbandry industry.

  • Case Presentations in Heart Disease

    • 2nd Edition
    • Alan Mackintosh
    • English
    Case Presentations in Heart Disease: Second Edition presents cases dealing with the diagnosis and treatment of patients with a heart related problem. This book addresses the need for a sample of real life cardiologic problems. Some of the topics covered in the book are the case of the 63-year-old brewery worker with severe pain between the shoulder blades; a case of a 54 years old woman with pain in her right loin; a case of a man applying for insurance; and a case of a married man who experienced loss of consciousness lasting 5 minutes. Other topics discussed include the causes of dissecting aortic aneurysm, the diagnosis made on the female with pain in her right loin, and the development of atrial myxomas. The acute phase of a myocardial infarction is presented. The concluding part is devoted to the analysis of a case of coughing symptom with no smoking history. The book can provide useful information to doctors, cardiologists, students, and researchers.

  • Principles of Horticulture

    • 2nd Edition
    • C.R. Adams + 2 more
    • English
    Principles of Horticulture, Second Edition covers the various topics concerning plant cultivation for agricultural use. The book is comprised of 17 chapters that tackle the various areas of concerns in horticulture. The coverage of the text includes the nurturing aspects of horticulture, including growth and development, genetics and breeding, and nutrition. The book also covers the various threats and problems encountered by horticulturists, such as pests, weeds, and harmful microorganisms. The text will be of great use to researchers and practitioners of plant-related fields, such as botany, agriculture, and particularly horticulture.

  • The Origins of Agriculture

    An Evolutionary Perspective
    • 1st Edition
    • David Rindos
    • English
    The Origins of Agriculture: An Evolutionary Perspective presents an alternative approach to understanding cultural variation and change. It aims to demonstrate that domestication and the origin of agricultural systems are best understood by attempting to explicate the evolutionary forces that affected that development of domesticates and agricultural systems. The book begins by discussing cultural change, the domestication of plants, and the origin of agricultural systems in the most general of terms. It considers Darwinism in some depth, concentrating on the relationship between natural selection and cultural change. Subsequent chapters examine the world of domestication and agriculture and present a series of concepts that may permit a more natural explanation for these processes. These include concepts such as incidental domestication, specialized domestication, and agricultural domestication. The final two chapters present models for the origin and spread of agricultural systems based upon Darwinian evolutionary theory.

  • Catalytic RNA

    • 1st Edition
    • Volume 120
    • English
    This special volume of Progress in Molecular Biology and Translational Science focuses on catalytic RNA. Written by experts in the field, the reviews cover a range of topics, from hammerhead ribozymes to spliceosome catalysis to Varkud satellite and hairpin ribozymes.

  • Biomaterials for Cancer Therapeutics

    Diagnosis, Prevention and Therapy
    • 1st Edition
    • Kinam Park
    • English
    Cancer can affect people of all ages, and approximately one in three people are estimated to be diagnosed with cancer during their lifetime. Extensive research is being undertaken by many different institutions to explore potential new therapeutics, and biomaterials technology is now being developed to target, treat and prevent cancer. This unique book discusses the role and potential of biomaterials in treating this prevalent disease.The first part of the book discusses the fundamentals of biomaterials for cancer therapeutics. Chapters in part two discuss synthetic vaccines, proteins and polymers for cancer therapeutics. Part three focusses on theranosis and drug delivery systems, whilst the final set of chapters look at biomaterial therapies and cancer cell interaction.This extensive book provides a complete overview of the latest research into the potential of biomaterials for the diagnosis, therapy and prevention of cancer. Biomaterials for cancer therapeutics is an essential text for academics, scientists and researchers within the biomedical industry, and will also be of interest to clinicians with a research interest in cancer therapies and biomaterials.

  • Pharma's Prescription

    How the Right Technology Can Save the Pharmaceutical Business
    • 1st Edition
    • Kamal Biswas
    • English
    The pharmaceutical industry needs a shot in the arm – and not a moment too soon. The executive suite is mired in a bygone era, a time when extensive, well-funded pharmaceutical R&D produced blockbuster drugs, kept everything in-house and reaped the financial rewards. But that way of working needs to change. Executives now need to know what the technologists in their companies are doing in order to survive the next decade. Written for those new to industry, as well as for experienced professionals or specialists looking to expand their knowledge, this book is a must-read for business executives and information technologists alike. Pharma’s Prescription bridges the knowledge gap between current business practices and the most valuable technologies today. This book is filled with practical, real-life examples from industry and is a straightforward guide for all pharmaceutical and information technology executives who need to improve their businesses.

  • From Academia to Entrepreneur

    Lessons from the Real World
    • 1st Edition
    • Eugene Khor
    • English
    From Academia to Entrepreneur: Lessons from the Real World provides practical advice on entrepreneurship, interspersed with insights the author gained from starting up his own business and in associations with other ventures. These same insights can be applied to bringing a technology concept from academia to an enterprise. A few of the questions From Academia to Entrepreneur: Lessons from the Real World answers: How do I pragmatically appraise business opportunities? What traits should I look for in an enterprise? What can and should I do with my concept while in academia, before entering such an endeavor? How do I overcome risk aversion? And most importantly, why should I be the one to build this business?

  • Receptor-Receptor Interactions

    • 1st Edition
    • Volume 117
    • P. Michael Conn
    • English
    This new volume of Methods in Cell Biology looks at receptor-receptor interactions, with sections on allosteric and effector interactions, crystallization and modeling, measuring receptor-receptor interactions and oligomerization in individual classes. With cutting-edge material, this comprehensive collection is intended to guide researchers of receptor-receptor interactions for years to come.

  • Principles of Tissue Engineering

    • 4th Edition
    • Robert Lanza + 2 more
    • English
    Now in its fourth edition, Principles of Tissue Engineering has been the definite resource in the field of tissue engineering for more than a decade. The fourth edition provides an update on this rapidly progressing field, combining the prerequisites for a general understanding of tissue growth and development, the tools and theoretical information needed to design tissues and organs, as well as a presentation by the world’s experts of what is currently known about each specific organ system. As in previous editions, this book creates a comprehensive work that strikes a balance among the diversity of subjects that are related to tissue engineering, including biology, chemistry, material science, and engineering, among others, while also emphasizing those research areas that are likely to be of clinical value in the future. This edition includes greatly expanded focus on stem cells, including induced pluripotent stem (iPS) cells, stem cell niches, and blood components from stem cells. This research has already produced applications in disease modeling, toxicity testing, drug development, and clinical therapies. This up-to-date coverage of stem cell biology and other emerging technologies –such as brain-machine interfaces for controlling bionics and neuroprostheses– is complemented by a series of new and updated chapters on recent clinical experience in applying tissue engineering, as well as a new section on the application of tissue-engineering techniques for food production. The result is a comprehensive textbook that will be useful to students and experts alike.

  • The HDL Handbook

    Biological Functions and Clinical Implications
    • 2nd Edition
    • Tsugikazu Komoda
    • English
    The HDL Handbook: Biological Functions to Clinical Implications brings laboratory research in HDL from bench to bedside in this needed resource for researchers and clinicians studying cholesterol, lipids, epidemiology, biochemistry, molecular medicine, and pathophysiology of cardiovascular diseases. In addition, researchers and clinicians working with an aging population, corporate researchers, post-doctorates; medical students and graduate students will find this publication useful because the scope of coverage includes basic science, genetics, epidemiology, and treatment of HDL cholesterol as well as potential targets to modify HDL cholesterol.

  • Quest for the Cure

    Reflections on the Evolution of Breast Cancer Treatment
    • 1st Edition
    • George R. Blumenschein
    • English
    This original fourteen chapter book is a brief, slightly autobiographic tale of medical oncologists, surgeons, radiation oncologists, and breast cancer patients in a well-established cancer center in Texas, who pursued the goal of cure for breast cancer. The evolution of improved outcomes in the treatment of microscopic metastatic breast cancer is also the story of the development of adjuvant chemotherapy for post-operative breast disease. The adjuvant therapy of breast cancer came about with the realization that this malignancy, when diagnosed in most patients, had spread beyond the confines of the primary cancer.

  • De Indiae utriusque re naturali et medica libri quatuordecim

    • 1st Edition
    • Willem Piso
    • English

  • Using Secondary Datasets to Understand Persons with Developmental Disabilities and their Families

    • 1st Edition
    • Volume 45
    • English
    International Review of Research in Developmental Disabilities is an ongoing scholarly look at research into the causes, effects, classification systems, syndromes, etc. of developmental disabilities. Contributors come from wide-ranging perspectives, including genetics, psychology, education, and other health and behavioral sciences.

  • Membrane Research: Classic Origins and Current Concepts

    • 1st Edition
    • A. L. Muggleton-Harris
    • English
    Membrane Research: Classic Origins and Current Concepts is a special volume of the International Review of Cytology dedicated to Dr. Danielli on the occasion of his retirement from official duties. The central theme of the volume is membranes. The diversity of topics ranges from the biogenesis of membranes and their components, to the use of optical and lectin probes as a means to study the structure, physiology, and interactions of cell components and organelles in plant and animal systems. The book begins with a study on the cell surface of the mammalian embryo and the events associated with the formation of the differentiated blastocyst. This is followed by separate chapters on the structural associations between the inner and outer bacterial membrane; the interactions of cell wall and membrane in plant cells; the morphological and functional aspects of membranes; and methods for studying the physiology of cell and organelles at the membrane level. Subsequent chapters deal with the synthesis of cellular proteins and glycoproteins; techniques for fixing and preserving the ultrastructure of the membrane; the synthesis of artificial organelles; and the effects of drugs and chemicals on membrane transport utilizing kidney tissue and vesicles. This book provides an outstanding reference source for all scientific researchers and teachers.

  • Biology of the Rhizobiaceae

    International Review of Cytology, Vol. 13
    • 1st Edition
    • Kenneth L. Giles + 1 more
    • English
    Biology of the Rhizobiaceae covers the genetics, molecular biology, agricultural, and morphological aspects of the rhizobia. The book discusses the taxonomy and identification of the Rhizobiaceae; the biology of Agrobacterium tumefaciens and the specific events in the disease cycle of crown gall; and the agricultural control of Agrobacterium tumefaciens. The text also describes the growth potential of crown gall tumors and crown gall teratoma; plasmid studies in crown gall tumorigenesis; and the biology and microbiology of Agrobacterium rhizogenes. The recognition in rhizobium-legume symbioses; the rhizobium bacteroid state; and the exchange of metabolites and energy between legume and rhizobium are also considered. The book further tackles the mutants of rhizobium that are altered in legume interaction and nitrogen fixation; as well as the significance and application of Rhizobium in agriculture. Botanists, agriculturists, geneticists, molecular biologists, microbiologists, plant pathologists, and agronomists will find the book invaluable.

  • Plant Protoplasts

    International Review of Cytology, Vol. 16
    • 1st Edition
    • Kenneth L. Giles
    • English
    Plant Protoplasts covers the techniques involved with, and uses of, protoplast technology. The book discusses isolation, fusion, and culture of higher plant protoplasts, lower plant protoplasts, and blue-green algal protoplast. The text also describes the production of haploid protoplasts from developing pollen grains; the use of protoplasts in mutant selection schemes, and the development of protoplast systems for use with monocotyledonous plants. The book will be invaluable to plant technologists, botanists, biochemists, research workers as well as advanced students interested in gaining a background knowledge of the field.

  • Pharmaceutics

    Basic Principles and Application to Pharmacy Practice
    • 1st Edition
    • Alekha Dash + 1 more
    • English
    Pharmaceutics: Basic Principles and Application to Pharmacy Practice is an engaging textbook that covers all aspects of pharmaceutics with emphasis on the basic science and its application to pharmacy practice. Based on curricular guidelines mandated by the American Council for Pharmacy Education (ACPE), this book incorporates laboratory skills by identifying portions of each principle that can be used in a clinical setting. In this way, instructors are able to demonstrate their adherence to ACPE standards and objectives, simply by using this book. Written in a straightforward and student-friendly manner, Pharmaceutics enables students to gain the scientific foundation to understand drug physicochemical properties, practical aspects of dosage forms and drug delivery systems, and the biological applications of drug administration. Key ideas are illustrated and reinforced through chapter objectives and chapter summaries. A companion website features resources for students and instructors, including videos illustrating difficult processes and procedures as well as practice questions and answers. Instructor resources include Powerpoint slides and a full-color image bank. This book is intended for students in pharmaceutical science programs taking pharmaceutics or biopharmaceutics courses at the undergraduate, graduate and doctoral level.

  • A History of Modern Immunology

    The Path Toward Understanding
    • 1st Edition
    • Zoltan A. Nagy
    • English
    A History of Modern Immunology: A Path Toward Understanding describes, analyzes, and conceptualizes several seminal events and discoveries in immunology in the last third of the 20th century, the era when most questions about the biology of the immune system were raised and also found their answers. Written by an eyewitness to this history, the book gives insight into personal aspects of the important figures in the discipline, and its data driven emphasis on understanding will benefit both young and experienced scientists. This book provides a concise introduction to topics including immunological specificity, antibody diversity, monoclonal antibodies, major histocompatibility complex, antigen presentation, T cell biology, immunological tolerance, and autoimmune disease. This broad background of the discipline of immunology is a valuable companion for students of immunology, research and clinical immunologists, and research managers in the pharmaceutical and biotechnology industries.

  • Regenerative Medicine Applications in Organ Transplantation

    • 1st Edition
    • Giuseppe Orlando
    • English
    Regenerative Medicine Applications in Organ Transplantation illustrates exactly how these two fields are coming together and can benefit one another. It discusses technologies being developed, methods being implemented, and which of these are the most promising. The text encompasses tissue engineering, biomaterial sciences, stem cell biology, and developmental biology, all from a transplant perspective. Organ systems considered include liver, renal, intestinal, pancreatic, and more. Leaders from both fields have contributed chapters, clearly illustrating that regenerative medicine and solid organ transplantation speak the same language and that both aim for similar medical outcomes. The overall theme of the book is to provide insight into the synergy between organ transplantation and regenerative medicine. Recent groundbreaking achievements in regenerative medicine have received unprecedented coverage by the media, fueling interest and enthusiasm in transplant clinicians and researchers. Regenerative medicine is changing the premise of solid organ transplantation, requiring transplantation investigators to become familiar with regenerative medicine investigations that can be extremely relevant to their work. Similarly, regenerative medicine investigators need to be aware of the needs of the transplant field to bring these two fields together for greater results.

  • Tabacologia

    Hoc est, Tabaci, seu nicotianae descriptio medico-cheirurgico-pharmaceutica
    • 1st Edition
    • Johann Neander
    • English

  • Insect Resistance Management

    Biology, Economics, and Prediction
    • 2nd Edition
    • David W. Onstad
    • English
    Neither pest management nor resistance management can occur with only an understanding of pest biology. For years, entomologists have understood, with their use of economic thresholds, that at least a minimal use of economics was necessary for proper integrated pest management. IRM is even more complicated and dependent on understanding and using socioeconomic factors. The new edition of Insect Resistance Management addresses these issues and much more. Many new ideas, facts and case studies have been developed since the previous edition of Insect Resistance Management published. With a new chapter focusing on Resistance Mechanisms Related to Plant-incorporated Toxins and heavily expanded revisions of several existing chapters, this new volume will be an invaluable resource for IRM researchers, practitioners, professors and advanced students. Authors in this edition include professors at major universities, leaders in the chemical and seed industry, evolutionary biologists and active IRM practitioners. This revision also contains more information about IRM outside North America, and a modeling chapter contains a large new section on uncertainty analysis, a subject recently emphasized by the U.S. Environmental Protection Agency. The final chapter contains a section on insecticidal seed treatments. No other book has the breadth of coverage of Insect Resistance Management, 2e. It not only covers molecular to economic issues, but also transgenic crops, seed treatments and other pest management tactics such as crop rotation. Major themes continuing from the first edition include the importance of using IRM in the integrated pest management paradigm, the need to study and account for pest behavior, and the influence of human behavior and decision making in IRM.

  • Salt and Water Balance

    Proceedings of the Third International Pharmacological Meeting July 24–30, 1966
    • 1st Edition
    • K. H. Beyer + 1 more
    • English
    Salt and Water Balance, Volume 8 presents the proceedings of the 3rd International Pharmacological Meeting, held in Sao Paulo, Brazil, on July 24–30, 1966. This book features the modulation of renal control of electrolyte and water balance, which is the most effective approach of handling most clinical problems wherein fluid retention needs to be reduced. Comprised of 10 chapters, this compilation of papers starts with an overview of the diuretic agents that are effective diuretic therapy. This text then describes the active transport, which proceeds at the expense of energy against the combined chemical and electrical gradients in the case of electrolytes. Other chapters consider the historical importance in therapy and the mechanisms of action of mercurial diuretics. This book discusses as well the complications and unwanted side effects of diuretic therapy. The final chapter deals with the hemodynamic mechanisms and their possible influence on the tubular function. This book is a valuable resource for physicians, health care professionals, and patients.

  • Lipid Droplets

    • 1st Edition
    • Volume 116
    • H. Robert Yang + 1 more
    • English
    This new volume of Methods in Cell Biology looks at lipid droplets LDs, covering sections on analyses of LDs in model systems, cell/tissue-specific analyses of LDs and imaging and in vitro analyses of LD biogenesis and growth. Chapters are written by experts in the field. With cutting-edge material, this comprehensive collection is intended to guide researchers of LDs for years to come.

  • Stock Identification Methods

    Applications in Fishery Science
    • 2nd Edition
    • Steven X. Cadrin + 2 more
    • English
    Stock Identification Methods, 2e, continues to provide a comprehensive review of the various disciplines used to study the population structure of fishery resources. It represents the worldwide experience and perspectives of experts on each method, assembled through a working group of the International Council for the Exploration of the Sea. The book is organized to foster interdisciplinary analyses and conclusions about stock structure, a crucial topic for fishery science and management. Technological advances have promoted the development of stock identification methods in many directions, resulting in a confusing variety of approaches. Based on central tenets of population biology and management needs, this valuable resource offers a unified framework for understanding stock structure by promoting an understanding of the relative merits and sensitivities of each approach.

  • Interdisciplinary Mentoring in Science

    Strategies for Success
    • 1st Edition
    • Ofelia Olivero
    • English
    Interdisciplinary Mentoring in Science: Strategies for Success is a practical and engaging resource on interdisciplinary mentoring in all fields of science. This book outlines what successful mentoring is, what it is not and how these important concepts relate to scientists today. Chapters include real-world examples, tips, and interviews and content is backed by current evidence and research. This reference discusses the benefits and challenges of building a mentoring relationship and highlights noteworthy topics such as mentoring minorities and women and mentoring to achieve change. The book’s author is the recipient of the Leading Diversity Award from the National Cancer Institute. The book includes a foreword by Julie Thompson Klein who is a Professor of Humanities in the English Department and Faculty Fellow for Interdisciplinary Development in the Division of Research at Wayne State University in Detroit, Michigan. Dr. Klein is the past president of the Association for Integrative Studies (AIS) and former editor of the AIS journal, Issues in Integrative Studies. The goal of this book is to provide readers with a better understanding of the mentoring relationship and the overall process as it applies to the increasingly interdisciplinary field of science.

  • Innovations in Food Packaging

    • 2nd Edition
    • Jung H. Han
    • English
    This new edition of Innovations in Food Packaging ensures that readers have the most current information on food packaging options, including active packaging, intelligent packaging, edible/biodegradable packaging, nanocomposites and other options for package design. Today's packaging not only contains and protects food, but where possible and appropriate, it can assist in inventory control, consumer education, increased market availability and shelf life, and even in ensuring the safety of the food product. As nanotechnology and other technologies have developed, new and important options for maximizing the role of packaging have emerged. This book specifically examines the whole range of modern packaging options. It covers edible packaging based on carbohydrates, proteins, and lipids, antioxidative and antimicrobial packaging, and chemistry issues of food and food packaging, such as plasticization and polymer morphology. Professionals involved in food safety and shelf life, as well as researchers and students of food science, will find great value in this complete and updated overview.

  • Blood Platelets in Man and Animals

    • 1st Edition
    • Bernard Maupin
    • G. A. Kerkut
    • English
    Blood Platelets in Man and Animals in Two Volumes, Volume 1 presents a general synopsis of all fields of interest in the study of platelets including a chapter dealing with Blood Platelets in Animals. The literature contains many surveys and discussions on the cytology, immunology, hematology and pathology of blood platelets. The monograph is a definitive review of the major aspects of blood platelets. The book begins with the introduction of the general aspects of the study of blood platelets. Subsequent chapters are devoted to the methods of separation and study of blood platelets; morphology and physical properties of blood platelets; physiological and experimental variations in the number of platelets; and platelet functions in coagulation, hemostasis and thrombogenesis. The last chapter presents studies of platelets in other classes of vertebrates and invertebrates. Cytologists, physiologists, biochemists, immunologists, physicians, veterinarians, biologists, and hematologists will find the book very useful.

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