Essays in Toxicology
Volume 1
- 1st Edition - January 1, 1969
- Latest edition
- Editor: Frank R. Blood
- Language: English
Essays in Toxicology, Volume 1 covers essays in toxicology and related topics. The book presents essays on the use of poisons as tools in studying the nervous system as well as… Read more
Essays in Toxicology, Volume 1 covers essays in toxicology and related topics. The book presents essays on the use of poisons as tools in studying the nervous system as well as teratology. The text also includes essays on the significance of methemoglobinemia in toxicology and lead poisoning. Biochemists, plant and animal physiologists, pharmacologists, pathologists, microbiologists, entomologists, food technologist, and people involved in forensic medicine and industrial medicine.
List Of Contributors
Preface
1. Poisons as Tools in Studying the Nervous System
I. Introduction
II. Axonic Transmission
A. The Poisons
B. The System
III. Excitatory Synaptic Transmission
A. The Poisons
B. Actions on the Receptor
C. Actions on Transmitter Synthesis and Release
D. Actions on Transmitter Destruction
IV. Inhibitory Synaptic Transmission
A. The Poisons
B. Inhibition in Vertebrates
C. Inhibition in Invertebrates
D. Inhibition: Current and Future Uses of Poisons
References
2. Teratology
I. Introduction
II. Placental Physiology
III. Research Needs
IV. Nutritional Aspects
V. Genetic Factors
VI. Drugs
VII. Infectious Diseases
VIII. Mechanistic Causes
IX. Conclusion
References
3. The Significance of Methemoglobinemia in Toxicology
I. Introduction
II. Therapeutic and Experimental Applications
A. Cyanide Poisoning
B. Sulfide Poisoning
C. Miscellaneous Toxic Anions
III. Methemoglobinemia as a Toxic Reaction
A. Hypoxic Responses of Man and Animals
B. Cause of Death in Methemoglobinemia
C. Treatment of Toxic Methemoglobinemia
IV. Pharmacology of Methylene Blue
A. Methemoglobin Formation by Methylene Blue
B. Cyanide Poisoning
C. Carbon Monoxide Poisoning
D. Methylene Blue in Oxygen Lack
E. Miscellaneous Actions
V. Summary
References
4. Lead Poisoning. An Old Problem with a New Dimension
I. Introduction
II. Historical Background
III. Industrial Lead Poisoning
IV. Lead Poisoning in Infants
V. Lead Poisoning in Domesticated Animals and Wildlife
VI. Sources and Uses of Lead
VII. Tetraethyl Lead and the General Environment
VIII. Perspectives Regarding Problem-Solving
IX. Current Knowledge Bearing on Existing Problems
X. The Metabolism of Lead
A. Absorption
B. The Fate of Lead in the Body
XI. Toxic Effects of Lead
A. The Effect of Lead on the Hemopoietic System
B. Effects of Lead on the Central and Peripheral Nervous System
C. Effects of Lead on the Kidney
D. Miscellaneous Effects
XII. Lead as Related to the Incidence of Diseases
XIII. The Body Burden of Lead in the General Population
A. Estimates of Body Burden
B. Environment and the Body Burden
XIV. The Evaluation of Blood Levels
A. "Classic" Lead Poisoning
B. Lead-Related Diseases
XV. The Role of Animal Experimentation
XVI. The New Dimension
References
Author Index
Subject Index
- Edition: 1
- Latest edition
- Published: January 1, 1969
- Language: English
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