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Elsevier

Books in Life sciences

  • Biometals in Neurodegenerative Diseases

    Mechanisms and Therapeutics
    • 1st Edition
    • Anthony R. White + 3 more
    • English
    Biometals in Neurodegenerative Diseases: Mechanisms and Therapeutics is an authoritative and timely resource bringing together the major findings in the field for ease of access to those working in the field or with an interest in metals and their role in brain function, disease, and as therapeutic targets. Chapters cover metals in Alzheimer’s Disease, Parkinson’s Disease, Motor Neuron Disease, Autism and lysosomal storage disorders. This book is written for academic researchers, clinicians and advanced graduate students studying or treating patients in neurodegeneration, neurochemistry, neurology and neurotoxicology. The scientific literature in this field is advancing rapidly, with approximately 300 publications per year adding to our knowledge of how biometals contribute to neurodegenerative diseases. Despite this rapid increase in our understanding of biometals in brain disease, the fields of biomedicine and neuroscience have often overlooked this information. The need to bring the research on biometals in neurodegeneration to the forefront of biomedical research is essential in order to understand neurodegenerative disease processes and develop effective therapeutics.

  • Lepidoptera Genetics

    International Series of Monographs in Pure and Applied Biology: Zoology
    • 1st Edition
    • Roy Robinson
    • G. A. Kerkut
    • English
    Lepidoptera Genetics provides a systematic account of the genetics and karyology of Lepidoptera. Topics covered include the use of biometry in genetic studies; population genetics and polymorphism; the rise of industrial melanism; and the evolution of mimicry. The genetics of Rhopalocera and Heterocera is also discussed. This book is comprised of eight chapters and begins with an overview of Lepidoptera species and their genetics, paying particular attention to color and pigmentation, breeding, and resistance to insecticides, as well as the effect of seasonal variations and the environment on Lepidoptera. The next chapter outlines the tenets of genetics that are of value for Lepidoptera research, including particulate heredity, random assortment, sex-linked inheritance, maternal inheritance, and mosaicism. The reader is methodically introduced to the application of biometry to the study of Lepidoptera genetics; the evolution of mimicry in Lepidoptera; and the known heredity of Rhopalocera and Heterocera. The final chapter examines the karyology of Lepidoptera, focusing on the haploid karyotype, polyploidy, chiasmata frequency, supernumerary chromosomes, and sex chromatin. This monograph will be a useful resource for entomologists, geneticists, and biologists.

  • Mixed-Species Groups of Animals

    Behavior, Community Structure, and Conservation
    • 1st Edition
    • Eben Goodale + 2 more
    • English
    Mixed-Species Groups of Animals: Behavior, Community Structure, and Conservation presents a comprehensive discussion on the mixed-species groups of animals, a spectacular and accessible example of the complexity of species interactions. They are found in a wide range of animals, including invertebrates, fish, mammals and birds, and in different habitats, both terrestrial and aquatic, throughout the world. While there are more than 500 articles on this subject scattered in separate categories of journals, there has yet to be a general, cross-taxa book-length introduction to this subject that summarizes the behavior and community structure of these groups. The authors first survey the diversity of spatial associations among animals and then concentrate on moving groups. They review the major classes of theories that have been developed to explain their presence, particularly in how groups increase foraging efficiency and decrease predation. Finally, they explore the intricacies of species interactions, such as communication, that explain species roles in groups and discuss what implications these social systems have for conservation.

  • The Pilchard

    Biology and Exploitation
    • 1st Edition
    • Michael Culley
    • G. A. Kerkut
    • English
    The Pilchard: Biology and Exploitation discusses various concerns in the global pilchard industry. The book is comprised of 23 chapters that are organized into five parts. The text first introduces the biology of pilchard, its geographical distribution, and its zoological classification. Parts II to IV tackle the various issues in pilchard industries in different regions, namely, England, California, South Africa, and West Africa. The coverage of the book includes catching, processing, demand, and profitability. The book will be of great use to individuals involved in the pilchard industries. Researchers of fisheries science will also benefit from the book.

  • The Microbiology of Skin, Soft Tissue, Bone and Joint Infections

    • 1st Edition
    • Volume 2
    • Kateryna Kon + 1 more
    • English
    The Microbiology of Skin, Soft Tissue, Bone and Joint Infections: Volume 2 discusses modern approaches in diagnosis, treatment, and prophylaxis of skin, soft tissue, bone, and joint infections. The volume has been divided into three sections. The first section includes chapters on diagnosis, treatment, and prophylaxis of skin and soft tissue infections. It discusses antimicrobial and surgical treatment of wounds, diabetic foot, and different soft tissue infections. Ten chapters are devoted to cutaneous and musculoskeletal infections in special groups of patients, which have their own specificity, i.e. in pediatric and HIV-infected patients. Together with chapters on commonly present diseases, there are chapters which discuss interesting but not well studied pathologies (natal cleft pilonidal sinus) and pathogens (Malassezia and Shewanella spp.). The second section reviews etiology, pathogenesis, diagnosis and treatment of bone and joint infections, mainly osteomyelitis and prosthetic joint infections. Also, one chapter in this section discusses a newly emerging bacterial pathogen that causes skeletal infections, Kingella kingae. The third section incorporates alternative and new approaches—such as nanotechnology, ultrasound, novel delivery approaches and phyto-derived medicines—to the treatment and prophylaxis of skin, soft tissue, bone, and joint infections.

  • Arthropod Vector: Controller of Disease Transmission, Volume 2

    Vector Saliva-Host-Pathogen Interactions
    • 1st Edition
    • Stephen K. Wikel + 2 more
    • English
    Arthropod Vector: Controller of Disease Transmission, Volume 2: Vector Saliva-Host Pathogen Interactions is built on topics initially raised at a related Keystone Symposium on Arthropod Vectors. Together with the separate, related Volume 1: Controller of Disease Transmission, this work presents a logical sequence of topic development that leads to regulatory considerations for advancing these and related concepts for developing novel control measures. The three themes of symbionts, vector immune defenses and arthropod saliva modulation of the host environment are central to the concept of determinants of vector competence that involves all aspects of vector-borne pathogen development within the arthropod that culminates in the successful transmission to the vertebrate host. These three areas are characterized at the present time by rapid achievement of significant, incremental insights, which advances our understanding for a wide variety of arthropod vector species, and this work is the first to extensively integrate these themes.

  • Epigenetics and Systems Biology

    • 1st Edition
    • Leonie Ringrose
    • English
    Epigenetics and Systems Biology highlights the need for collaboration between experiments and theoretical modeling that is required for successful application of systems biology in epigenetics studies. This book breaks down the obstacles which exist between systems biology and epigenetics researchers due to information barriers and segmented research, giving real-life examples of successful combinations of systems biology and epigenetics experiments. Each section covers one type of modeling and one set of epigenetic questions on which said models have been successfully applied. In addition, the book highlights how modeling and systems biology relate to studies of RNA, DNA, and genome instability, mechanisms of DNA damage signaling and repair, and the effect of the environment on genome stability.

  • Early Warning for Infectious Disease Outbreak

    Theory and Practice
    • 1st Edition
    • Weizhong Yang
    • English
    Early Warning for Infectious Disease Outbreak: Theory and Practice is divided into three parts, with the first section introducing basic theory and key technologies of early warning and the basic principles of infectious disease surveillance. The second section introduces the technical details in the process of establishment, operation and usage of CIDARS and Pudong Syndromic Surveillance and the Early Warning System of the Shanghai World Expo. The third part explores the study of early warning technology, collecting some useful exploration in the fields of infectious diseases involving sentinel setting, data analysis, influence factors study, calculation and evaluation of early warning models.

  • Arthropod Vector: Controller of Disease Transmission, Volume 1

    Vector Microbiome and Innate Immunity of Arthropods
    • 1st Edition
    • Stephen K. Wikel + 2 more
    • English
    Arthropod Vector: Controller of Disease Transmission, Volume 1: Vector Microbiome and Innate Immunity of Arthropods is built on topics initially raised at a related Keystone Symposium on Arthropod Vectors. Together with the separate, related Volume 2: Vector Saliva-Host Pathogen Interactions, this work presents a logical sequence of topic development that leads to regulatory considerations for advancing these and related concepts for developing novel control measures. The three themes of symbionts, vector immune defenses and arthropod saliva modulation of the host environment are central to the concept of determinants of vector competence that involves all aspects of vector-borne pathogen development within the arthropod that culminates in the successful transmission to the vertebrate host. These three areas are characterized at the present time by rapid achievement of significant, incremental insights, which advances our understanding for a wide variety of arthropod vector species, and this work is the first to extensively integrate these themes.

  • A Roadmap for Curing Cancer, Alzheimer's, and Cardiovascular Disease

    • 1st Edition
    • Paul J. Marangos
    • English
    Cancer, dementia, and cardiovascular disease are responsible for almost two million deaths each year in the United States alone and represent the largest immediate threat to humanity. Over the last century, we have made spectacular advances that have transformed our society – splitting the atom, space travel, telecommunications, and the Internet – but with medical research focused mostly on science for the sake of science, it has yielded precious few cures. A Roadmap for Curing Cancer, Alzheimer’s, and Cardiovascular Disease represents a "first of its kind" effort to address both the reasons for this and to posit solutions to fix our broken system, in an effort to finally end this cure crisis. Dr. Marangos draws on 45 years of experience in every aspect of the biomedical R&D field, from basic drug discovery research at the NIH to the co-founding of five drug companies. He has published 252 research papers and edited four books on drug discovery, is co-inventor on 14 patents, and founded "The Journal of Molecular Neuroscience". He argues that from a development perspective, the regulatory, patent, and legal hurdles that force industry to pursue so-called "me-too" drugs rather than cures for terminal diseases must be re-thought. Leadership accountability, strategy, focus, and urgency need to be re-evaluated, and major reforms to the NIH, FDA, and patent codes are proposed.to remedy these impediments to cures. Written for anyone frustrated with the seemingly endless threat of terminal disease, this book seeks to inform, energize, and provide the rationale for the public and industry stakeholders, as well as clinicians and researchers, to resurrect the physician-patient relationship and demand that we get serious about ridding society of this scourge on humanity. This work contains the views and opinions of the author and are in no way intended to harm the reputation of any person, agency, organization, or commercial entity discussed herein. www.cureterminaldise...

  • Advances in Applied Microbiology

    • 1st Edition
    • Volume 99
    • English
    Advances in Applied Microbiology, Volume 99 continues is one of the most widely read and authoritative review sources in microbiology, containing comprehensive reviews of the most current research in applied microbiology. This volume presents comprehensive information on a variety of topics, including the Physiological Role of Two-Component Signal Transduction Systems in Food-Associated Lactic Acid Bacteria, Fungal Bio recovery of Gold from E-Waste, Stone-Eating Fungi: Mechanisms in Bio weathering and the Potential Role of Laccases in Black Slate Degradation with the Basidiomycete Schizophyllum commune, and the Arsenic Detoxification System in Corynebacteria: Basis and Application for Bioremediation and Redox Control. This serial's eclectic volumes are supplemented by thematic volumes on various topics, including Archaea and sick building syndrome. Users will find invaluable references and information on a variety of areas, including protozoan grazing of freshwater biofilms, metals in yeast fermentation processes, the interpretation of host-pathogen dialogue through microarrays, and the role of polyamines in bacterial growth and biofilm formation.

  • Brain-Based Learning and Education

    Principles and Practice
    • 1st Edition
    • Yi-Yuan Tang
    • English
    Brain-Based Learning and Education presents a new type of education that uses brain-based and self-control theory-driven training. Leaving aside the current focus in education on content knowledge, it examines essential character strengths such as selfcontrol, persistence, creativity, attention, memory, and social learning, and relates their relevance to learning. By bridging the research and application gap in education, this text not only covers the latest findings related to learning and teaching but also provides insights for application and practice for brain-based methods in health and education. This integration of neuroscience and education takes us from a deep understanding of brain function to the frontline of the classroom.

  • Advances in Virus Research

    • 1st Edition
    • Volume 98
    • English
    Advances in Virus Research, Volume 98, the latest in a series first published in 1953, covers a diverse range of in-depth reviews, providing a valuable overview of the current field of virology. Topics in this new release include Zoonotic Potential of Emerging Paramyxoviruses: Knowns and Unknowns, Metabolomics: Strategies to Define the Role of Metabolism in Virus Infection and Pathogenesis, The Envelope Proteins of the Bunyavirales, and Insect-Specific Viruses: A Historical Overview and Recent Developments. The series is a valuable resource for information on all topics of virus research, from bacteriophages, to human viruses.

  • Hormone Metabolism and Signaling in Plants

    • 1st Edition
    • Jiayang Li + 2 more
    • English
    Plant Hormones: Biosynthesis and Mechanisms of Action is based on research funded by the Chinese government’s National Natural Science Foundation of China (NSFC). This book brings a fresh understanding of hormone biology, particularly molecular mechanisms driving plant hormone actions. With growing understanding of hormone biology comes new outlooks on how mankind values and utilizes the built-in potential of plants for improvement of crops in an environmentally friendly and sustainable manner. This book is a comprehensive description of all major plant hormones: how they are synthesized and catabolized; how they are perceived by plant cells; how they trigger signal transduction; how they regulate gene expression; how they regulate plant growth, development and defense responses; and how we measure plant hormones. This is an exciting time for researchers interested in plant hormones. Plants rely on a diverse set of small molecule hormones to regulate every aspect of their biological processes including development, growth, and adaptation. Since the discovery of the first plant hormone auxin, hormones have always been the frontiers of plant biology. Although the physiological functions of most plant hormones have been studied for decades, the last 15 to 20 years have seen a dramatic progress in our understanding of the molecular mechanisms of hormone actions. The publication of the whole genome sequences of the model systems of Arabidopsis and rice, together with the advent of multidisciplinary approaches has opened the door to successful experimentation on plant hormone actions.

  • Profiles of Drug Substances, Excipients, and Related Methodology

    • 1st Edition
    • Volume 42
    • English
    Profiles of Drug Substances, Excipients, and Related Methodology, Volume 42 presents comprehensive reviews of drug substances and additional materials, with critical review chapters that summarize information related to the characterization of drug substances and excipients, thus meeting the needs of the pharmaceutical community and allowing for the development of a timely vehicle for publishing review materials on the topic. This latest release covers a variety of substances, including Cinacalcet Hydrochloride, Clenbuterol Hydrochloride, Gliclazide, Lomefloxacin, Olmesartan, Propranolol, and Tolterodine Tartrate. The scope of the Profiles series encompasses review articles and database compilations that fall within one of the following six broad categories, Physical profiles of drug substances and excipients, Analytical profiles of drug substances and excipients, Drug metabolism and pharmacokinetic profiles of drug substances and excipients, Methodology related to the characterization of drug substances and excipients, Methods of chemical synthesis, and Reviews of the uses and applications for individual drug substances, classes of drug substances, or excipients.

  • Congenital Adrenal Hyperplasia

    A Comprehensive Guide
    • 1st Edition
    • Peter C. Hindmarsh + 1 more
    • English
    Congenital Adrenal Hyperplasia: A Comprehensive Guide addresses how hydrocortisone works, what can go wrong, and how to correct it, also explaining why the timing of doses and measurement of cortisol from a dose is extremely important. The book provides an in-depth analysis of this disorder for pediatric endocrinologists and primary care providers, allowing them to help patients with an updated model of care and appropriate treatment. Patients and family members will benefit from the trend-forward information that will empower them to approach their healthcare providers with the expectation of receiving individualized care and treatment for this disorder.

  • Dementia, An Issue of Neurologic Clinics

    • 1st Edition
    • Volume 35-2
    • John M. Ringman
    • English
    This issue of Neurologic Clinics, edited by Dr. John Ringman, will cover a wider variety of topics and the latest updated on Demantia. Topics covered in this issue include, but are not limited to Updates on the basic science of AD; The role of neuropsychology in the assessment of the cognitively impaired elderly; Assessment of the Spanish-speaking cognitively impaired elderly; Early-Onset Alzheimer’s disease; Vascular dementia and vascular contributions to Alzheimer’s disease; Frontotemporal Degenerations; and Current and Experimental Treatments, among others.

  • Advances in Clinical Chemistry

    • 1st Edition
    • Volume 80
    • English
    Advances in Clinical Chemistry, Volume 80, the latest installment in this internationally acclaimed series, covers a variety of topics relating to the topic. Users will find new chapters on Triglycerides Revisited to the Serial, PCR-Based Detection Methods for Single Nucleotide Polymorphism or Mutation: Real-Time PCR and its Substantial Contribution Towards Technological Refinement, Advances in Circulating Tumor DNA Analysis, Advances in Molecular Diagnosis of Malaria, and Rapid Assessment of Drugs of Abuse. This series contains chapters authored by world-renowned clinical laboratory scientists, physicians and research scientists who discuss the latest and most up-to-date technologies related to the field of clinical chemistry. Users of this series will find a resource that is considered to be the benchmark for novel analytical approaches in the clinical laboratory.

  • Advances in Agronomy

    • 1st Edition
    • Volume 143
    • English
    Advances in Agronomy, Volume 143 continues to be recognized as a leading reference and first-rate source for the latest research in agronomy. This latest release brings new and updated information on Soil: The Forgotten Piece of the Water, Food, Energy Nexus, Humin: Its Composition and Importance in Soil Organic Matter, the Effects of Drought Stress on Morpho-Physiological Traits, Biochemical Characteristics, Yield and Yield Components in Different Ploidy Wheat: A Meta-Analysis, and a section on the Delineation of Soil Management Zones for Variable Rate Fertilization - A Review. Each volume in this series contains an eclectic group of reviews by leading scientists throughout the world. As always, the subjects covered are rich, varied, and exemplary of the abundant subject matter addressed by this long-running serial.

  • Translational Bioinformatics and Systems Biology Methods for Personalized Medicine

    • 1st Edition
    • Qing Yan
    • English
    Translational Bioinformatics and Systems Biology Methods for Personalized Medicine introduces integrative approaches in translational bioinformatics and systems biology to support the practice of personalized, precision, predictive, preventive, and participatory medicine. Through the description of important cutting-edge technologies in bioinformatics and systems biology, readers may gain an essential understanding of state-of-the-art methodologies. The book discusses topics such as the challenges and tasks in translational bioinformatics; pharmacogenomics, systems biology, and personalized medicine; and the applicability of translational bioinformatics for biomarker discovery, epigenomics, and molecular dynamics. It also discusses data integration and mining, immunoinformatics, and neuroinformatics. With broad coverage of both basic scientific and clinical applications, this book is suitable for a wide range of readers who may not be scientists but who are also interested in the practice of personalized medicine.

  • Wilson Disease

    • 1st Edition
    • Volume 142
    • Anna Czlonkowska + 1 more
    • English
    Wilson Disease provides a comprehensive guide on this inherited genetic disorder that has devastating consequences for both the liver and neurologic/psychiatr... health. This disease is of increasing interest to neurologists, hepatologists, and geneticists, but when the disease is diagnosed early, it is treatable, with patients living normal lives. This volume describes the molecular pathophysiology of WD and the clinical and pathological effects of copper. Separate sections address both diagnosis and medical and surgical approaches to treatment. Both adult and pediatric perspectives on diagnosis and treatment are addressed, and a section on genetics highlights advances in molecular diagnostics. Patient support groups that can aid in coping with this disease are also discussed, as are animal models for those interested in basic research on cell biology, pathophysiology, and treatment.

  • 3D Printing in Medicine

    • 1st Edition
    • Deepak M. Kalaskar
    • English
    3D Printing in Medicine examines the emerging market of 3D-printed biomaterials and its clinical applications. With a particular focus on both commercial and premarket tools, the book looks at their applications within medicine and the future outlook for the field. The book begins with a discussion of the fundamentals of 3D printing, including topics such as materials, and hardware. Chapters go on to cover applications within medicine such as computational analysis of 3D printed constructs, personalized 3D printing and 3D cell and organ printing. The concluding chapters in the book review the applications of 3D printing in diagnostics, drug development, 3D-printed disease models and 3D printers for surgical practice. With a strong focus on the translation of 3D printing technology to a clinical setting, this book is a valuable resource for scientists and engineers working in biomaterial, biomedical, and nanotechnology based industries and academia.

  • Stress and Inflammation in Disorders

    • 1st Edition
    • Volume 108
    • English
    Stress and Inflammation in Disorders, Volume 108, the newest volume in this ongoing series, brings forth new information on protocols and analysis of proteins. This volume covers the latest on Oxidative Stress: Love and Hate History in the Central Nervous System, Neuroinflammation in Alzheimer's Disease: The Preventive and Therapeutic Potential of Polyphenolic Nutraceuticals, Inflammation in Epileptic Encephalopathies, A Computational Approach to Identify the Biophysical and Structural Aspect of Methylenetetrahydrof... Reductase (MTHFR) Mutations (A222V, E429A and R594Q) Leading to Schizophrenia, and Analyzing the Effect of V66M Mutation in BDNF in Causing MOOD Disorders- A Computational Approach. Each release in the Advances in Protein Chemistry and Structural Biology series is an essential resource for protein chemists, with each thematically organized volume guest edited by leading experts in a broad range of protein-related topics.

  • Advances in Food and Nutrition Research

    • 1st Edition
    • Volume 82
    • English
    Advances in Food and Nutrition Research, Volume 82 provides updated knowledge on nutrients in foods and how to avoid deficiency. Topics covered in this latest release include Phenolic Compounds and its Bioavailability: In Vitro Bioactive Compounds or Health Promoters?, Health Risks of Food Oxidation, Metabolomics, Nutrition, and Potential Biomarkers of Food Quality, Intake, and Health Status, Improvement of Soybean Products Through the Response Mechanism Analysis Using Proteomic Technique, and Nanotechnology for Food Packaging and Food Quality Assessment. This resource is especially useful for those interested in the essential nutrients that should be present in the diet to reduce disease risk and optimize health. It provides the latest advances on the identification and characterization of emerging bioactive compounds with putative health benefits, as well as up-to-date information on food science, including raw materials, production, processing, distribution and consumption, with an emphasis on nutritional benefits and health effects.

  • Multifunctional Agriculture

    Achieving Sustainable Development in Africa
    • 1st Edition
    • Roger Leakey
    • English
    In a world increasingly challenged by the need to integrate and understand highly specialized knowledge in a multidisciplinary way, this book is innovative and perhaps unique in addressing this challenge. 　It focuses on ideas, strategies, techniques and practices spanning many disciplines　at the interface of agriculture with: forestry, horticulture, plant physiology, genetics, ecology, soil science, food science, economics, and the social and environmental sciences as delivered by intensified and enriched agroforestry. Multifunctional Agriculture　addresse... this complexity, using case studies and insights from the needs of African farmers whose livelihoods are constrained by complex interactions between social, environmental and economic factors and problems underlying agricultural sustainability in Africa.　This book, therefore, provides an important resource for those trying to understand the role of agriculture in the achievement of the new Sustainable Development Goals by providing easily implementable, practical and effective methodologies and practices.　

  • Unconventional Oilseeds and Oil Sources

    • 1st Edition
    • Abdalbasit Adam Mariod + 2 more
    • English
    Unconventional Oilseeds and New Oil Sources: Chemistry and Analysis is presented in three parts, with each section dedicated to different types of oil sources. Part One deals with plants (vegetable, herbs, shrubs), such as Hibiscus, Mexican Poppy, Cucumber, Squashes, Sesame, etc. Part Two presents unconventional oils found in trees (like Balanites aegyptiaca, Annona squamosal and Catunaregam nilotica), and Part Three deals with new oils found in insects, as in the water melon bug and sorghum bug. This book will be of interest to researchers in oilseed production, research and development personnel, food scientists, plant breeders, product development personnel, and government agency personnel involved in the production, transportation, distribution, and processing of oilseeds.

  • Algal Green Chemistry

    Recent Progress in Biotechnology
    • 1st Edition
    • Rajesh Prasad Rastogi + 2 more
    • English
    Algal Green Chemistry: Recent Progress in Biotechnology presents emerging information on green algal technology for the production of diverse chemicals, metabolites, and other products of commercial value. This book describes and emphasizes the emerging information on green algal technology, with a special emphasis on the production of diverse chemicals, metabolites, and products from algae and cyanobacteria. Topics featured in the book are exceedingly valuable for researchers and scientists in the field of algal green chemistry, with many not covered in current academic studies. It is a unique source of information for scientists, researchers, and biotechnologists who are looking for the development of new technologies in bioremediation, eco-friendly and alternative biofuels, biofertilizers, biogenic biocides, bioplastics, cosmeceuticals, sunscreens, antibiotics, anti-aging, and an array of other biotechnologically important chemicals for human life and their contiguous environment. This book is a great asset for students, researchers, and biotechnologists.

  • Matrix Metalloproteinases and Tissue Remodeling in Health and Disease: Cardiovascular Remodeling

    • 1st Edition
    • Volume 147
    • English
    Matrix Metalloproteinases and Tissue Remodeling in Health and Disease: Cardiovascular Remodeling, Volume 147 contains up-to-date information on the biology and function of matrix metalloproteinases and how their effects on tissue remodeling are altered in diseases of the cardiovascular, pulmonary, and musculoskeletal systems and in other tissues and organs, and in cancer. This latest release covers such highly evolving topics as Biochemical and Biological Attributes of Matrix Metalloproteinases, Matrix Metalloproteinases in Myocardial Infarction and Heart Failure, The Balance Between Metalloproteinases and TIMPs: Critical Regulator of Microvascular Endothelial Cell Function in Health and Disease, and Matrix Metalloproteinases and Platelet Function. As part of the Progress in Molecular Biology and Translational Science, users will find contributions from prominent scientists and highly-recognized experts who have major accomplishments in the research field of matrix metalloproteinases.

  • Machine Dreaming and Consciousness

    • 1st Edition
    • J. F. Pagel + 1 more
    • English
    Machine Dreaming and Consciousness is the first book to discuss the questions raised by the advent of machine dreaming. Artificial intelligence (AI) systems meeting criteria of primary and self-reflexive consciousness are often utilized to extend the human interface, creating waking experiences that resemble the human dream. Surprisingly, AI systems also easily meet all human-based operational criteria for dreaming. These “dreams” are far different from anthropomorphic dreaming, including such processes as fuzzy logic, liquid illogic, and integration instability, all processes that may be necessary in both biologic and artificial systems to extend creative capacity. Today, multi-linear AI systems are being built to resemble the structural framework of the human central nervous system. The creation of the biologic framework of dreaming (emotions, associative memories, and visual imagery) is well within our technical capacity. AI dreams potentially portend the further development of consciousness in these systems. This focus on AI dreaming raises even larger questions. In many ways, dreaming defines our humanity. What is humanly special about the states of dreaming? And what are we losing when we limit our focus to its technical and biologic structure, and extend the capacity for dreaming into our artificial creations? Machine Dreaming and Consciousness provides thorough discussion of these issues for neuroscientists and other researchers investigating consciousness and cognition.

  • The Complete Reference for Scimitar Syndrome

    Anatomy, Epidemiology, Diagnosis and Treatment
    • 1st Edition
    • Vladimiro Vida
    • English
    The Complete Reference for Scimitar Syndrome: Anatomy, Epidemiology, Diagnosis and Treatment gives the complete picture of this rare syndrome that is usually treated with tactics such as imaging. The book goes beyond imaging, providing a pathological and clinical description of this rare syndrome. All aspects beginning with development, clinical presentation, current surgical options (including recent techniques) and indications to treat patients based on current results coming from multicenter study experiences are included. This book is a must-have reference for all cardiologists, cardiac surgeons, thoracic surgeons, pathologists, physicians, residents and students involved in Scimitar Syndrome cases.

  • NanoArmoring of Enzymes: Rational Design of Polymer-Wrapped Enzymes

    • 1st Edition
    • Volume 590
    • English
    Nanoarmoring of Enzymes: Rational Design of Polymer-Wrapped Enzymes, Volume 590 is the latest volume in the Methods in Enzymology series that focuses on nanoarmoring of enzymes and the rational design of polymer-wrapped enzymes. This new volume presents the most updated information on a variety of topics, including specific chapters on Encapsulating Proteins in Nanoparticles: Batch by Batch or One by One, Enzyme Adsorption on Nanoparticle Surfaces Probed by Highly Sensitive Second Harmonic Light Scattering, Armoring Enzymes by Metal–Organic Frameworks by the Coprecipitation Method, and Enzyme Armoring by an Organosilica Layer: Synthesis and Characterization of Hybrid Organic/Inorganic Nanobiocatalysts. Users will find this to be an all-encompassing resource on nanoarmoring in enzymes.

  • Electronic Waste

    Toxicology and Public Health Issues
    • 1st Edition
    • Bruce A. Fowler
    • English
    Electronic Waste: Toxicology and Public Health Issues discusses the major public health concerns due to the presence of toxic chemicals that are generated from improper recycling and disposal practices of electronic waste (e-waste). This book highlights hazardous inorganic chemicals found in e-waste, including arsenic, cadmium, lead, mercury, gallium, iridium, and nanomaterials, also focusing on health issues related to the presence of BPA, styrene, and other plastic components and combustion products, while also identifying populations at special risk. To provide readers with potential solutions to this global problem, Dr. Fowler presents risk assessment approaches using chemicals, mixtures, biomarkers, susceptibility factors, and computational toxicology. He discusses how to translate the information gathered through risk assessment into safe and effective international policies. The final chapter is devoted to future research directions. This is a timely and useful resource for all those concerned with the health issues surrounding e-waste management and proper disposal, including toxicologists, public health and policy officials, environmental scientists, and risk assessors.

  • Advances in Immunology

    • 1st Edition
    • Volume 134
    • English
    Advances in Immunology, Volume 134, the latest release in a long-established and highly respected publication, presents current developments and comprehensive reviews in immunology. Topics covered in this new volume include γδ T Cells and B Cells, A Chemoattractant-Guid... Walk Through Lymphopoiesis: From Hematopoietic Stem Cells to Mature B Lymphocytes. Tissue Specific Regulation of Dendritic Cell Development and Function, and the Regulation of Innate and Adaptive Immunity by Transforming Growth Factor Beta (TGFβ). Articles in this long running series address the wide range of topics that comprise immunology, including molecular and cellular activation mechanisms, phylogeny and molecular evolution, and clinical modalities. Edited and authored by the foremost scientists in the field, each volume provides up-to-date information and directions for the future.

  • Sweet Potato Processing Technology

    • 1st Edition
    • Taihua Mu + 3 more
    • English
    Sweet Potato Processing Technology systematically introduces processing technologies of sweet potato starch and its series products including sweet potato protein, dietary fibers, pectin, granules, anthocyanins and chlorogenic acids. The book provides a detailed and comprehensive account of physicochemical and functional properties of sweet potato products, the nutritional components extracted from sweet potato, as well as their utilization in food, medicine and cosmetic fields. This book can provide the scientific basis and technical support for virtuous circle promotion and structure upgrade of sweet potato processing industry. This book will be a valuable reference for undergraduate and graduate students, as well as specialists and enterprise research staff in the field of food technology.

  • Advances in Imaging of Multiple Sclerosis, An Issue of Neuroimaging Clinics of North America

    • 1st Edition
    • Volume 27-2
    • Alex Rovira
    • English
    This issue of Neuroimaging Clinics of North America focuses on Imaging of Multiple Sclerosis: Diagnosis and Management, and is edited by Dr. Àlex Rovira Cañellas. Articles will include: Multiple Sclerosis: Epidemiological, Clinical and Therapeutic Aspects; Brain and Spinal Cord MR Imaging Features in Multiple Sclerosis and Variants; Neuromyelitis Optica Spectrum Disorders; Radiologically Isolated Syndrome; MRI in Monitoring and Predicting Treatment Response in Multiple Sclerosis; Cortical Grey Matter MR Imaging in Multiple Sclerosis; Brain Atrophy in Multiple Sclerosis: Technical Aspects and Clinical Relevance; Iron Mapping in Multiple Sclerosis; Microstructural MR Techniques in Multiple Sclerosis; Molecular and Metabolic Imaging in Multiple Sclerosis; Insights from Ultra-high Field Imaging in Multiple Sclerosis; Pediatric Multiple Sclerosis: Distinguishing Clinical and MRI Features, and more!

  • Nanostructures for Oral Medicine

    • 1st Edition
    • Ecaterina Andronescu + 1 more
    • English
    Nanostructures for Oral Medicine presents an up-to-date examination of the applications and effects of nanostructured materials in oral medicine, with each chapter addressing recent developments, specific applications, and uses of nanostructures in the oral administration of therapeutic agents in dentistry. The book also includes coverage of the biocompatibility of nanobiomaterials and their remarkable potential in improving human health and in reducing environmental pollution. Emerging advances, such as Dr. Franklin Tay's concept of a new nanotechnology process of growing extremely small, mineral-rich crystals and guiding them into the demineralized gaps between collagen fibers to prevent the aging and degradation of resin-dentin bonding is also discussed. This work will be of great value to those who work in oral medicine, providing them with a resource to gain a greater understanding of how nanotechnology can help them create more efficient, cost-effective products. In addition, it will be of great interest to those who work in materials science who wish to gain a greater appreciation of how nanostructured materials are applied in this field.

  • It's in Your DNA

    From Discovery to Structure, Function and Role in Evolution, Cancer and Aging
    • 1st Edition
    • Eugene Rosenberg
    • English
    Approx.202 pages

  • Network Functions and Plasticity

    Perspectives from Studying Neuronal Electrical Coupling in Microcircuits
    • 1st Edition
    • Jian Jing
    • English
    Network Functions and Plasticity: Perspectives from Studying Neuronal Electrical Coupling in Microcircuits focuses on the specific roles of electrical coupling in tractable, well-defined circuits, highlighting current research that offers novel insights for electrical coupling‘s roles in sensory and motor functions, neural computations, decision-making, regulation of network activity, circuit development, and learning and memory. Bringing together a diverse group of international experts and their contributions using a variety of approaches to study different invertebrate and vertebrate model systems with a focus on the role of electrical coupling/gap junctions in microcircuits, this book presents a timely contribution for students and researchers alike.

  • Fundamental Techniques in Virology

    • 1st Edition
    • Karl Habel
    • English

  • Design—Operation Interactions at Large Treatment Plants

    Proceedings of a Workshop Held in Vienna
    • 1st Edition
    • S. H. Jenkins
    • English
    Design-Operation Interactions at Large Treatment Plants deals with the different plans and designs to improve large treatment plans, the feasibility of these plans, the problems they might entail, and the solutions for current and prospective problems these treatment plants may face. The book shows the possible new directions that treatment plants may go to through assessment, planning, and new technology, as well as the the design for the treatment plants and the many considerations to be kept in mind in designing of one. Also included is an instructional guide on the functions an importance of the different parts of the treatment plant, the specific problems and their solutions, and improvements that can be done to it. The text is recommended for engineers and planners working in treatment plants, those in charge of sanitation and urban development and improvement, government agencies who wish to evaluate and even propose plans of building a treatment plant, and environmentalists who wish to know more about the treatment plant.

  • Mycotoxins in Foodstuffs — 3

    Invited Lectures Presented at the Third International IUPAC Symposium on Mycotoxins in Foodstuffs, Paris, France, 16 - 18 September, 1976
    • 1st Edition
    • M. Jemmali
    • English
    Mycotoxins in Foodstuffs—3 is a collection of invited lectures presented at the International Union of Pure and Applied Chemistry's Third International Symposium on Mycotoxins in Foodstuffs, held in Paris, France, on September 16-18, 1976. The papers explore the health hazards posed by mycotoxins found in foodstuffs, including aflatoxins and trichothecenes, as well as ways of addressing the problem. This book is comprised of 11 chapters and begins with a discussion on how to design a program for monitoring problem foods and surveying potential problem foods for a number of mycotoxins. The next chapter describes a methodology for the design and evaluation of testing programs to estimate aflatoxin concentrations in granular foodstuffs. The action taken by various countries regarding mycotoxins in foodstuffs (food and feed), under legislative provision or code of practice, is then examined. Subsequent chapters deal with the metabolism of aflatoxin and other mycotoxins in relation to their toxicity and the accumulation of residues in animal tissues; mode of action of trichothecenes; and mode of action and human health aspects of aflatoxin carcinogenesis. The human health hazards associated with mycotoxins are also considered, along with prevention, elimination, and detoxification of aflatoxins. This monograph will be a useful resource for chemists, nutritionists, food scientists, and toxicologists.

  • Systems Factorial Technology

    A Theory Driven Methodology for the Identification of Perceptual and Cognitive Mechanisms
    • 1st Edition
    • Daniel Little + 3 more
    • English
    Systems Factorial Technology: A Theory Driven Methodology for the Identification of Perceptual and Cognitive Mechanisms explores the theoretical and methodological tools used to investigate fundamental questions central to basic psychological and perceptual processes. Such processes include detection, identification, classification, recognition, and decision-making. This book collects the tools that allow researchers to deal with the pervasive model mimicry problems which exist in standard experimental and theoretical paradigms and includes novel applications to not only basic psychological questions, but also clinical diagnosis and links to neuroscience. Researchers can use this book to begin using the methodology behind SFT and to get an overview of current uses and future directions. The collected developments and applications of SFT allow us to peer inside the human mind and provide strong constraints on psychological theory.

  • Smart Technologies for Sustainable Smallholder Agriculture

    Upscaling in Developing Countries
    • 1st Edition
    • David Chikoye + 2 more
    • English
    Smart Technologies for Sustainable Smallholder Agriculture: Upscaling in Developing Countries defines integrated climate smart agricultural technologies (ICSAT) as a suite of interconnected techniques and practices that enhance quantity and quality of agricultural products with minimum impact on the environment. These ICSAT are centered on three main pillars, increased production and income, adaptation and resilience to climate change, and minimizing GHG emissions. This book brings together technologies contributing to the three pillars, explains the context in which they can be scaled up, and identifies research and development gaps as areas requiring further investigation. It stresses the urgency in critically analyzing and recommending ICSAT and scaling out the efforts of both developing and disseminating these in an integrated manner. The book discusses, synthesizes, and offers alternative solutions to agriculture production systems and socio-economic development. It brings together biophysical and socioeconomic disciplines in evaluating suitable ICSAT in an effort to help reduce poverty and food insecurity.

  • Planning and Evaluation of Irrigation Projects

    Methods and Implementation
    • 1st Edition
    • Raveendra Kumar Rai + 2 more
    • English
    Planning and Evaluation of Irrigation Projects: Methods and Implementation presents the considerations, options and factors necessary for effective implementation of irrigation strategies, going further to provide methods for evaluating the efficiency of systems-in-place for remedial correction as needed. As the first book to take this lifecycle approach to agricultural irrigation, it includes real-world examples not only on natural resource availability concerns, but also on financial impacts and measurements. With 21 chapters divided into two sections, this book is a valuable resource for agricultural and hydrology engineers, conservation scientists and anyone seeking to implement and maintain irrigation systems.

  • Advances in the Study of Behavior

    • 1st Edition
    • Volume 49
    • Marc Naguib
    • English
    Advances in the Study of Behavior, Volume 49 provides users with the latest insights in this ever-evolving field. Users will find new information on a variety of species, including social behaviors in reptiles, the behavioral evidence of felt emotions, a section on developmental plasticity, a chapter on covetable corpses and plastic beetles and the socioecological behavior of burying beetles, and a section on the mechanisms of communication and cognition in chickadees. This volume makes another important contribution to the development of the field by presenting theoretical ideas and research findings to professionals studying animal behavior and related fields. Researchers in a variety of behavioral fields will find this longstanding series, initiated over 40 years ago, to be a go-to resource for the study of animal behavior.

  • How to Optimize Fluid Bed Processing Technology

    Part of the Expertise in Pharmaceutical Process Technology Series
    • 1st Edition
    • Dilip Parikh
    • English
    How to Optimize Fluid Bed Processing Technology: Part of the Expertise in Pharmaceutical Process Technology Series addresses the important components of fluid bed granulation, providing answers to problems that commonly arise and using numerous practical examples and case studies as reference. This book covers the theoretical concepts involved in fluidization, also providing a description of the choice and functionality of equipment. Additional chapters feature key aspects of the technology, including formulation requirements, process variables, process scale-up, troubleshooting, new development, safety, and process evaluation. Given its discussion of theoretical principles and practical solutions, this is a go-to resource for all those scientists and new researchers working with fluid bed granulation as a unit operation.

  • Advances in Nanomedicine for the Delivery of Therapeutic Nucleic Acids

    • 1st Edition
    • Surendra Nimesh + 2 more
    • English
    Advances in Nanomedicine for the Delivery of Therapeutic Nucleic Acids addresses several issues related to safe and effective delivery of nucleic acids (NAs) using nanoparticles. A further emphasis would be laid on the mechanism of delivery of NAs, the barriers encountered and the strategies adapted to combat them. An exhaustive account of the advantages as well shortcomings of all the delivery vectors being employed in delivery of various NAs will be provided. On final note the regulatory aspects of nanoparticles mediated NA would be discussed, with focus on their clinical relevance. The design and development of nucleic acid-based therapeutics for the treatment of diseases arising from genetic abnormalities has made significant progress over the past few years. NAs have been widely explored for the treatment of cancer and infectious diseases or to block cell proliferation and thereby caused diseases. Advances in synthetic oligonucleotide chemistry resulted in synthesis of NAs that are relatively stable in in vivo environments. However, cellular targeting and intracellular delivery of NAs still remains a challenge. Further development of NA-based therapeutics depends on the progress of safe and effective carriers for systemic administration. Nanomedicine has facilitated availability of vectors with diminished cytotoxicity and enhanced efficacy which are rapidly emerging as systems of choice. These vectors protect NAs from enzymatic degradation by forming condensed complexes along with targeted tissue and cellular delivery. During the past few years, a myriad reports have appeared reporting delivery of NAs mediated by nanoparticles. This book will provide an overview of nanoparticles being employed in the in vitro and in vivo delivery of therapeutically relevant NAs like DNA, siRNA, LNA, PNA, etc.

  • Proteomics in Food Science

    From Farm to Fork
    • 1st Edition
    • Michelle Lisa Colgrave
    • English
    Proteomics in Food Science: From Farm to Fork is a solid reference providing concepts and practical applications of proteomics for those in various disciplines of food science. The book covers a range of methods for elucidating the identity or composition of specific proteins in foods or cells related to food science, from spoilage organisms, to edible components. A variety of analytical platforms are described, ranging from the usage of simple electrophoresis, to more sophisticated mass spectrometry and bio-informatic platforms. The book is designed for food scientists, technologists, food industry workers, microbiologists, and public health workers, and can also be a valuable reference book for students.

  • Antimicrobial Stewardship

    • 1st Edition
    • Volume 2
    • Céline Pulcini + 3 more
    • English
    Antimicrobial Stewardship (AMS), Volume Two includes the experience of ESGAP workshops and courses on antibiotic stewardship since 2012. It combines clinical and laboratory information about AMS, with a focus on human medicine. The ESCMID study group on antibiotic policies (ESGAP) is one of the most productive groups in the field, organizing courses and workshops. This book is an ideal tool for the participants of these workshops. With short chapters (around 1500 words) written on different topics, the authors insisted on the following points: A ‘hands on’, practical approach, tips to increase success, a description of the most common mistakes, a global picture (out- and inpatient settings, all countries) and a short list of 10-20 landmark references.

  • Nanoencapsulation Technologies for the Food and Nutraceutical Industries

    • 1st Edition
    • Seid Mahdi Jafari
    • English
    Nanoencapsulation Technologies for the Food and Nutraceutical Industries is a compendium which collects, in an easy and compact way, state-of-the-art details on techniques for nanoencapsulation of bioactive compounds in food and nutraceutical industries. The book addresses important modern technologies, including biopolymer based nano-particle formation techniques, formulation based processes, such as nano-liposomes and nano-emulsions, process based nano-encapsulation, such as electro-spinning and nano-spray drying, natural nano-carrier based processes, like casein and starch nano-particles, and other recent advances. This definitive reference manual is ideal for researchers and industry personnel who want to learn more about basic concepts and recent developments in nanotechnology research.

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