Gonadotropins: From Bench Side to Bedside
- 1st Edition, Volume 143 - September 30, 2016
- Imprint: Academic Press
- Author: Rajendra T. Kumar
- Language: English
- Hardback ISBN:9 7 8 - 0 - 1 2 - 8 0 1 0 5 8 - 7
- eBook ISBN:9 7 8 - 0 - 1 2 - 8 0 1 2 6 6 - 6
Gonadotropins: From Bench Side to Bedside, the latest volume in the Progress in Molecular Biology and Translational Science series, focuses on all aspects of gonadotropins, f… Read more
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Gonadotropins: From Bench Side to Bedside, the latest volume in the Progress in Molecular Biology and Translational Science series, focuses on all aspects of gonadotropins, from research to treatment.
- Contains contributions from leading authorities on the topic
- Publishes cutting-edge reviews in molecular biology
- Informs and updates on all the latest developments available regarding the research of gonadotropins
Students, researchers, microbiologists, molecular biologists
Chapter One: Mouse Models of Gonadotrope Development
- Abstract
- 1. Introduction
- 2. Signaling Pathways
- 3. Transcription Factors
- 4. CRE Mice for Targeting Gonadotropes
- 5. Concluding Remarks
Chapter Two: Mouse Models for the Study of Synthesis, Secretion, and Action of Pituitary Gonadotropins
- Abstract
- 1. Introduction
- 2. α-Glycoprotein Hormone Subunit
- 3. LHβ Subunit
- 4. FSHβ Subunit
- 5. Transforming Growth Factor-β Superfamily Members and Gonadotropins
- 6. Other Mouse Models
- 7. Conclusions and Future Directions
- Acknowledgments
Chapter Three: Clinical Applications of Gonadotropins in the Female: Assisted Reproduction and Beyond
- Abstract
- 1. Introduction
- 2. Molecular Biology of the Ovarian Response
- 3. Gonadotropins in Assisted Reproduction
- 4. Ovarian Stimulation Protocols in ART
- 5. Adverse Events in Ovarian Stimulation
- 6. Gonadotropins Beyond ART
- 7. Conclusions
- Acknowledgments
Chapter Four: Clinical Applications of Gonadotropins in the Male
- Abstract
- 1. Introduction
- 2. Structural Features of the Gonadotropins
- 3. Regulation of the Synthesis and Secretion of the Pituitary Gonadotropins
- 4. Gonadotropin Secretion
- 5. Pharmacokinetics of Gonadotropins
- 6. Gonadotropin Formulations Available for Treating Hypogonadotropic Hypogonadism and Infertility in Men
- 7. Treatment with Gonadotropins in the Male
- 8. Concluding Remarks
- Acknowledgments
Chapter Five: Beyond Reproduction: Pituitary Hormone Actions on Bone
- Abstract
- 1. Evolutionary Considerations
- 2. Epidemiology Suggests an FSH–Bone Connection
- 3. FSH Directly Affects the Skeleton
- 4. FSH Signals Through FSHRs on Bone Cells
- 5. FSH Antibody Rescues Hypogonadal Bone Loss
- 6. Oxytocin is Anabolic to Bone
- 7. Oxytocin and Skeletal Regulation During Reproduction
- 8. Prolactin and Bone
Chapter Six: Gonadotrope Tumors
- Abstract
- 1. Introduction
- 2. Gonadotropes in the Normal Pituitary
- 3. Gonadotrope Hyperplasia
- 4. Gonadotrope Tumors
- 5. Conclusions
- Edition: 1
- Volume: 143
- Published: September 30, 2016
- Imprint: Academic Press
- Language: English
RK
Rajendra T. Kumar
Professor T. Rajendra Kumar works at the Department of Obstetrics & Gynecology, University of Colorado Denver.
Affiliations and expertise
Department of Obstetrics & Gynecology, University of Colorado Denver, Aurora, CO, USARead Gonadotropins: From Bench Side to Bedside on ScienceDirect