
Coronaviruses
- 1st Edition, Volume 96 - September 30, 2016
- Imprint: Academic Press
- Editor: John Ziebuhr
- Language: English
- Hardback ISBN:9 7 8 - 0 - 1 2 - 8 0 4 7 3 6 - 1
- eBook ISBN:9 7 8 - 0 - 1 2 - 8 0 5 1 1 5 - 3
Coronaviruses, the latest volume in the Advances in Virus Research series first published in 1953, covers a diverse range of in-depth reviews, providing a valuable overview of the… Read more

Purchase options

Institutional subscription on ScienceDirect
Request a sales quoteCoronaviruses, the latest volume in the Advances in Virus Research series first published in 1953, covers a diverse range of in-depth reviews, providing a valuable overview of the field. This series is a valuable resource for virologists, microbiologists, immunologists, molecular biologists, pathologists, and plant researchers.
- Contains contributions from leading authorities in virus research
- Provides comprehensive reviews for general and specialist use
- Presents the first and longest-running review series in virology
Chapter One: Supramolecular Architecture of the Coronavirus Particle
- Abstract
- 1 Introduction
- 2 Virion Structure and Durability
- 3 Viral Proteins in Assembly and Fusion
- 4 Evolution of the Structural Proteins
Chapter Two: Coronavirus Spike Protein and Tropism Changes
- Abstract
- 1 Introduction
- 2 Structure of the Coronavirus S Protein
- 3 Spike–Receptor Interactions
- 4 S Protein Proteolytic Cleavage and Conformational Changes
- 5 Tropism Changes Associated with S Protein Mutations
- 6 Concluding Remarks
- Acknowledgments
Chapter Three: The Nonstructural Proteins Directing Coronavirus RNA Synthesis and Processing
- Abstract
- 1 Introduction
- 2 Coronavirus nsp7–10: Small but Critical Regulatory Subunits?
- 3 Coronavirus nsp12: A Multidomain RNA Polymerase
- 4 Coronavirus nsp13: A Multifunctional and Highly Conserved Helicase Subunit
- 5 The Coronavirus Capping Machinery: nsp10–13–14–16
- 6 Coronavirus nsp14 ExoN: Key to a Unique Mismatch Repair Mechanism That Promotes Fidelity
- 7 Coronavirus nsp15: A Remarkable Endoribonuclease with Elusive Functions
- 8 Summary and Future Perspectives
- Acknowledgments
Chapter Four: Coronavirus cis-Acting RNA Elements
- Abstract
- 1 Introduction
- 2 Coronavirus Genome Replication and Transcription
- 3 Coronavirus cis-Acting RNA Elements
- 4 RNA Elements Involved in Coronavirus Genome Packaging
- 5 Possible Roles of Cellular Proteins in Coronavirus Replication
- 6 Conclusions and Outlook
- Acknowledgments
Chapter Five: Viral and Cellular mRNA Translation in Coronavirus-Infected Cells
- Abstract
- 1 Introduction
- 2 Mechanisms and Control of Translation of Coronavirus mRNAs
- 3 Host and Viral Factors That Regulate Coronavirus mRNA Translation
- 4 Coronavirus-Mediated Control of Host Translation
- 5 Concluding Remarks
- Acknowledgments
Chapter Six: Feline Coronaviruses: Pathogenesis of Feline Infectious Peritonitis
- Abstract
- 1 Feline Coronaviruses
- 2 Infection with Feline Coronaviruses
- 3 Molecular Pathogenesis of FIP
- 4 Reverse Genetics of Feline Coronaviruses
- 5 Perspectives
Chapter Seven: Interaction of SARS and MERS Coronaviruses with the Antiviral Interferon Response
- Abstract
- 1 Introduction
- 2 The Coronavirus Genome
- 3 The Type I IFN System
- 4 Antiviral Action of IFNs Against Human Coronaviruses
- 5 Evasion Strategies of Coronaviruses
- 6 Conclusions and Outlook
- Acknowledgments
Chapter Eight: Molecular Basis of Coronavirus Virulence and Vaccine Development
- Abstract
- 1 Introduction
- 2 Subunit, Inactivated, and Vectored Vaccines
- 3 Live-Attenuated Vaccines
- 4 Vaccine Biosafety
- 5 Coronavirus Antiviral Selection
- 6 Conclusions
- Acknowledgments
- Edition: 1
- Volume: 96
- Published: September 30, 2016
- Imprint: Academic Press
- No. of pages: 310
- Language: English
- Hardback ISBN: 9780128047361
- eBook ISBN: 9780128051153
JZ