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Patient Derived Tumor Xenograft Models

Promise, Potential and Practice

1st Edition - October 13, 2016

Editors: Rajesh Uthamanthil, Peggy Tinkey, Elisa de Stanchina

Language: English
Paperback ISBN:
9 7 8 - 0 - 1 2 - 8 0 4 0 1 0 - 2
eBook ISBN:
9 7 8 - 0 - 1 2 - 8 0 4 0 6 1 - 4

Patient Derived Tumor Xenograft Models: Promise, Potential and Practice offers guidance on how to conduct PDX modeling and trials, including how to know when these models are appro… Read more

Patient Derived Tumor Xenograft Models

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Patient Derived Tumor Xenograft Models: Promise, Potential and Practice offers guidance on how to conduct PDX modeling and trials, including how to know when these models are appropriate for use, and how the data should be interpreted through the selection of immunodeficient strains.

In addition, proper methodologies suitable for growing different type of tumors, acquisition of pathology, genomic and other data about the tumor, potential pitfalls, and confounding background pathologies that occur in these models are also included, as is a discussion of the facilities and infrastructure required to operate a PDX laboratory.