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Elsevier

Books in Neuroscience

Elsevier's Neuroscience collection empowers educators, researchers, and students with actionable knowledge to drive collaborative research and advancements in the field. Content covers the nervous system's intricate workings, covering branches like Affective, Behavioral, and Cognitive neuroscience to investigate the neural basis of emotions, behavior, and cognitive functions. Spanning from Molecular and Cellular Neuroscience to Developmental Neuroscience, content provides insights into brain function in health and disease.

  • Neurobiology of Motor Programme Selection

    New Approaches to the Study of Behavioural Choice
    • 1st Edition
    • J. Kien + 2 more
    • English
    The traditional view of motor systems as a linear chain of elements switched on and off by command neurons has become increasingly difficult to maintain in the face of accumulating evidence against the existence of command elements. So far, however, the general formulation of an alternative approach has been lacking. This book, by summarising the evidence against the linear approach to motor systems, argues forcefully against it. Analyses are presented of motor systems ranging from the lobster stomatogastric system through molluscan systems, leech movement, insect singing and locomotion, fish and amphibian behaviour, to goal-directed a movements in primates and volitional movements in humans. Comparison of these motor systems reveal the existence of some general principles underlying motor control and behavioural choice such that motor systems appear generally to be parallel, distributed processing networks. By discussing the treatment of motor systems in terms of parallel distributed processing systems, this book presents in concentrated form an alternative to the earlier view of motor systems. As such, the book is a must for all neuroscientists interested in the organisation of motor systems and the neuronal substrates of behavioural choice.

  • Studies in Neurolinguistics

    • 1st Edition
    • Haiganoosh Whitaker + 1 more
    • English
    Studies in Neurolinguistics, Volume 3 presents detailed case histories, multi-subject experimental studies, literature reviews, and research papers that employ a variety of experimental and observational techniques. This volume contains seven chapters that focus on a wide range of research in the field of neurolinguistics. Chapter 1 discusses the various approaches to the problem of auditory comprehension in aphasia. A survey of the world's literature on bilingualism and aphasia is provided in chapter 2. The third chapter examines the different models and explanations for conduction aphasia. Chapter 4 provides a synthesis of the anatomic, physiologic, and behavioral research on the role of the limbic system in human communication. Chapter 5 presents a model of individual differences in hemispheric functioning, in which a number of theories about the left and right hemispheres are analyzed and compared. Chapter 6 shows how different levels of language are revealed. The last chapter addresses "The Question of Electrophysiological Asymmetries Preceding Speech" in a study of the readiness potentials over the motor and premotor regions in eight subjects. Linguists, psychologists, and neurologists will find the book highly informative.

  • Neuro-psychopharmacology

    Proceedings of the Tenth Congress of the Collegium Internationale Neuro-Psychopharmacologicum Québec, July 4-9, 1976
    • 1st Edition
    • P. Deniker + 2 more
    • English

  • The Catecholamines in Psychiatric and Neurologic Disorders

    • 1st Edition
    • C. Raymond Lake + 1 more
    • English
    The Catecholamines in Psychiatric and Neurologic Disorders focuses on the contributions of catecholamines (CA) in the modulation of blood pressure, stress and exercise, body movements, memory, learning, emotions, thought processing, appetite, and mediation of psychotropic drug action. The selection first elaborates on the techniques for the assessment and interpretation of catecholamine measurements in neuropsychiatric patients and catecholaminergic response to stress and exercise. Discussions focus on noradrenergic response to isometric exercise, isotonic exercise, effect of acceleration on sympathetic activity, techniques for sympathetic nervous system evaluation, and measurements of CA and their metabolites in cerebrospinal fluid. The text then takes a look at urinary CA in behavioral research on stress; CA in anxiety disorders and mitral valve prolapse; and interaction with neurotransmitters in normal subjects and in patients with selected neurologic diseases. The selection examines noradrenergic responses in postural hypotension, norepinephrine, alcohol, and alcoholism, and catecholamine metabolism in anorexia nervosa. Topics include cerebral catecholamine metabolism in anorexia nervosa; central nervous system norepinephrine and voluntary alcohol drinking; and overview of norepinephrine in selected pediatric disorders. The book is a dependable reference for neuropsychiatrists and readers interested in the contributions of catecholamines on psychiatric disorders.

  • Neurobiology of Steroids

    • 1st Edition
    • Volume 22
    • P. Michael Conn + 1 more
    • English
    Steroid hormones are unique compounds in that they are active at the interface of peripheral endocrine events and neural mechanisms. Thus their effects present an important peripheral signaling system to alter brain function. This volume presents state-of-the-art and classical techniques for the study of steroid hormones and their receptors and their effects and actions.

  • Intensive Care for Neurological Trauma and Disease

    • 1st Edition
    • Barth A. Green + 2 more
    • English
    Intensive Care for Neurological Trauma and Disease presents the progress in intensive care in terms of technological development on life-support and monitoring systems. This book discusses the ideal neurologic intensive care environment that is based on developments in other specialized care units. Organized into 24 chapters, this book begins with an overview of the problem of neurological trauma. This text then presents the accident scene management protocol for acute spinal cord injury as a standard to other forms of trauma system pre-hospital care. Other chapters consider the appropriate drugs and dosages for the management of status epilepticus in the newborn and older children. This book discusses as well the findings on the neurological examination and provides a framework for an etiological classification that has direct therapeutic implications. The final chapter deals with the clinical aspects, diagnosis, and management of neuromuscular diseases. This book is a valuable resource for clinicians and intensive care unit nurses.

  • The Release of Catecholamines from Adrenergic Neurons

    • 1st Edition
    • David M. Paton
    • English
    The Release of Catecholamines from Adrenergic Neurons covers the advances in understanding the mechanism of catecholamine release and other neurotransmitters from adrenergic neurons. This book is organized into four sections encompassing 18 chapters. The opening section surveys biochemical studies of the mechanism and regulation of nerve stimulation. This section examines the role of calcium, prostaglandins, and presynaptic adrenoceptors and muscarine receptors in catecholamine release. The next section describes the modification of catecholamine release by several drugs, including adrenergic neuron blocking agents, narcotic analgesics, opioid peptides, lysergic acid diethylamide, anesthetics, alcohols, and adenosine and adenine nucleotides. These topics are followed by discussions of catecholamine release induced by cations and other drugs, such as nicotinic agonists, calcium ionophores, veratridine, scorption venom, and phenethylamines. The final section deals with the biochemical assessment of peripheral adrenergic activity and the clinical pharmacology of adrenergic neuron blocking agents. This book is intended for pharmacologists, neurologists, researchers, and advanced students.

  • The Neuropsychology of Consciousness

    • 1st Edition
    • A. D. Milner + 1 more
    • English
    The Neuropsychology of Consciousness is based on a symposium entitled “Consciousness and Cognition: Neuropsychological Perspectives” held at the University of St Andrews, September 1990. The intention was to assemble a group of the major researchers at the forefront of this field. The starting point for the symposium and for the book was the widespread realization that in several areas of human cognition (e.g. visual perception, memory, language comprehension, and attention), the severe and profound impairments due to brain damage that have been described over the past 150 years are often not absolute. In particular, the use of indirect methods of testing may reveal unsuspected preservation of capacities that are undetected by more traditional direct methods. The book opens with a discussion of the epidemic of dissociations and how well the phenomena within either neuropsychology or within normal human experimental psychology map onto each other. This is followed by separate chapters on topics such as blindsight, covert visual processing in patients, face recognition and awareness following brain injury, and the relationship between the study of attention and the understanding of consciousness.

  • Neurobiology of Cytokines

    Methods in Neurosciences, Vol. 16
    • 1st Edition
    • Errol B. De Souza
    • English
    Neurobiology of Cytokines, Part A provides an overview of the effects of cytokines in the brain and in the endocrine system. The book discusses the general aspects of cytokines, including the endogenous agonists and antagonists, their receptors, their second messengers, and transport mechanisms for cytokines across the blood-brain barrier. The text also describes the anatomical localization of cytokines, cytokine receptors, and their respective mRNA in brain and in endocrine tissues. The methods for evaluating the in vivo as well as in vitro actions of cytokines on hormone secretion are also considered. The book further tackles the synthesis and release of cytokines and their central nervous system actions; and the methodology for studying the role of cytokines in human neuropathological conditions.

  • Biophysical Aspects of Cerebral Circulation

    • 1st Edition
    • Yu. E. Moskalenko + 2 more
    • English
    Biophysical Aspects of Cerebral Circulation provides a comprehensive review of the cerebral circulatory system. This book consists of four chapters. Chapter 1 is devoted to methodology attempts to explain the special features of a biophysical approach. The biophysical principles of the most commonly used modem methods such as the clearance method and rheoencephalography are described in detail. The second and third chapters examine all the biophysical aspects of the cerebral circulatory system as a functional unit and deal with some principles of its regulation. The results of systems analysis using mathematical modeling are presented in broad outline. Chapter 4 deals with processes related to the regional cerebral circulation. Such investigations focus mainly on the relationship between periodically fluctuating factors affecting limited areas of brain tissue. This text is beneficial to medical students and individuals researching on cerebral circulation.

  • Neurological Emergencies

    • 1st Edition
    • S.D. Shorvon
    • English
    Neurological Emergencies presents a comprehensive guide on the initial assessment and early treatment of patients with neurological emergencies. It discusses the diagnosis, emergency investigations, and handling of coma patients. It addresses the management of focal supratentorial lesion. Some of the topics covered in the book are the diffuse neurological or systemic disturbance; emergency resuscitation; diagnosis and treatment of transtentorial herniation; diagnosis and treatment of acute viral encephalitis; raised intracranial pressure; diagnosis and treatment of non-viral infective encephalitis; viral meningitis; meningovascular syphilis; diagnosis and treatment of cerebral abscess; diagnosis and treatment of intracranial subdural empyema; and diagnosis and treatment of cerebral venous thrombosis. The diagnosis and treatment ofstroke is fully covered. An in-depth account of the difference between haemorrhage and infarction is provided. The diagnosis of subarachnoid haemorrhage is completely presented. A chapter is devoted to the prevention of more cranial bleeding.

  • Clinical Anesthesia in Neurosurgery

    • 1st Edition
    • Elizabeth A. M. Frost
    • English
    Clinical Anesthesia in Neurosurgery, Second Edition, integrates the evolution of the field of neuroanesthesia with the major areas of neurosurgical activity to give the reader the required perspective and requisite information to help in laying the foundation for future advances as well as describing the current state of the art. The book contains 25 chapters organized into five parts. Part I presents studies on cerebral physiology and evaluation. Topics covered include cerebral circulation and metabolism, intraoperative neurophysiologic monitoring, and central nervous system effects of anesthetic agents. Part II covers neurosurgical and related procedures, such as posterior cranial fossa surgery, surgery of the spine, and peripheral nerve surgery. Part III examines central nervous system trauma including spinal cord trauma and cardiovascular effects of severe head injury. Part IV takes up postoperative and intensive care, including postanesthetic care, neurosurgical intensive care, and parenteral nutrition while Part V deals with the medical criteria and legal aspects of brain death.

  • Case Presentations in Neurology

    • 1st Edition
    • G. S. Venables + 2 more
    • English
    Case Presentations in Neurology presents a selection of case histories demonstrating how patients with often quite simple problems may present and to bring out aspects of their diagnosis and management. All the patients presented to the Department of Neurology including those with more obscure diagnoses. The book consists of 12 exercises, each of six cases broadly corresponding to the style of the MRCP (UK) written case history papers. Each case is set out with the history and physical findings given first. There follows either a series of questions or true/false statements on one side of the page which the reader should attempt before continuing on to the answer section on the other side. There then follows a short discussion about each case and a single reference. This book is intended for those doctors studying for higher professional qualifications such as the MRCP, although it may be of interest and use to medical students approaching their final examinations.

  • Movement Disorders

    Neurology
    • 1st Edition
    • C. David Marsden + 1 more
    • English
    Neurology, Volume 2: Movement Disorders is a part of an international series of critical reviews of topics in neurology. This volume focuses on Parkinsonism and dyskinesia, a condition characterized by abnormal involuntary movements. Organized into 18 chapters, this book first elucidates the problems, causes, pathology, brain neurotransmitter changes and receptors, depression, dementia, fluctuations of disability, and treatment of Parkinson's disease. Subsequent chapters then explore the problems, controversies, and surgical approaches involved in certain dyskinesias. The role of dopamine receptors in movement disorders is also explored. This book will be valuable to neurologists-in-trai... as well as to those in research field or in practice in this field of interest. The book's clinical content will help in the management of patients with movement disorders.

  • Pulsatility in Neuroendocrine Systems

    • 1st Edition
    • Volume 20
    • Jon E. Levine + 1 more
    • English
    Pulsatility is now recognized as a nearly ubiquitous functional feature of neuroendocrine systems. This volume presents a comprehensive guide to the established and emerging technologies being used to study the perplexing phenomenon of pulsatility. Molecular, cellular, physiological, and mathematical approaches are described in detail.

  • Neuropathology

    Brussels, 21-28 July 1957
    • 1st Edition
    • L. Van Bogaert + 1 more
    • English
    Neuropathology, Volume IV presents the proceedings of the First International Congress of Neurological Sciences, held in Brussels, Belgium, on July 21–28, 1957. This book provides information pertinent to the fundamental aspects of neuropathology. Organized into 84 chapters, this compilation of papers begins with an overview of the problem of multiple sclerosis and its relationship to leucodystrophies. This text then explains the two major histopathological manifestations of the injury caused by the rabies virus in the central nervous system. Other chapters consider the successful identification and isolation of a biologically active compound, which depends to a large extent on the availability of a quantitative bioassay. This book discusses as well the clinical manifestations, pathogenesis, and treatment of multiple sclerosis. The final chapter deals with the study of nucleic acids as well as histochemistry as a method of histological inquiry. This book is a valuable resource for neuropsychiatrists, biochemists, physicians, and scientists.

  • Cognitive Development

    The Child's Acquisition of Diagonality
    • 1st Edition
    • David R. Olson
    • David S. Palermo
    • English
    Cognitive Development: The Child's Acquisition of Diagonality is an empirical and rational enquiry into the child's development of a conceptual system relating to the concept of the diagonal during the age range three to six years. A detailed examination will be made of why a young child has difficulty with such a problem, and what occurs during development that removes this difficulty. In the context of these empirical arguments, the book considers such theoretical questions as the nature of intellectual skills and conceptual or symbolic knowledge, as well as the role of experience and instruction in their development. The study concludes with a description of the child's reconstruction of the diagonal in terms of what at least poses as a general model of perceptual and intellectual development, and accounts for, among other things, man's increasing ability to apprehend and theorize about the motion of the stars. It shows that it is the elaboration of the child's perceptual knowledge in the context of his performatory attempts in such cultural media as language and geometry that accounts for his ability to copy a diagonal in particular and his intellectual development in general.

  • Neurosciences Research

    Volume 4
    • 1st Edition
    • S Ehrenpreis + 1 more
    • English
    Neuroscience Research, Volume 4 covers papers on a varied group of studies, ranging from synaptic transmission and local anesthetic action to the immobility reflex ("animal hypnosis") and control of food intake. The book presents papers on the mechanisms of synaptic transmission; the acetylcholine system and neural development; and the site of action and active form of local anesthetics. The text also includes papers on biological rhythms and their control in neurobehavioral perspective; neurophysiologic studies of the immobility reflex ("animal hypnosis" and the hepatic receptors and the neurophysiological mechanisms controlling feeding behavior. Neuroscientists, physiologists, and psychiatrists will find the book useful.

  • International Review of Neurobiology

    Supplement 1
    • 1st Edition
    • Carl C. Pfeiffer
    • English
    International Review of Neurobiology, Supplement 1: Neurobiology of the Trace Metals Zinc and Copper represents a first report in the study of the neurobiology of zinc and copper. Topics covered by this supplementary volume include the effects of zinc deficiency; the link between acute stress and trace element metabolism; the effects of trace elements on behavior; the pathophysiology of zinc; and the role of copper in schizophrenia. This book consists of seven chapters and begins with a historical overview of zinc deficiency syndrome in humans, followed by a discussion on the metabolism of zinc, effects of its deficiency, and its biochemical functions. Gross congenital malformations in zinc-deficient rats are highlighted. The reader is then introduced to the effect of acute stress on the metabolism of a trace element; the importance of trace elements to development and behavior; and the biological effect(s) of zinc. The next chapter is devoted to idiopathic hypogeusia with dysgeusia, hyposmia, and dysosmia, its symptoms, clinical pathology, and treatment. This monograph will be of value to neurobiologists, biochemists, and nutritionists.

  • Neurology

    What Shall I Do?
    • 1st Edition
    • Dafydd Thomas + 1 more
    • English
    Neurology: What shall I do? is a question and answer book that addresses the different kinds of neurological problems encountered by physicians everyday. The text serves as a quick reference guide for doctors and presents practical and simple approaches to certain neurological situations. The questions are grouped under broad headings such as epilepsy, headaches, weakness, fatigue, narcolepsy, and spinal problems. Answers to questions on pain problems, urinary difficulty, and how to categorize urgent and non-urgent cases are presented as well. Physicians, surgeons, and medical students will find the book very useful.

  • Neural Models of Plasticity

    Experimental and Theoretical Approaches
    • 1st Edition
    • John H. Byrne + 1 more
    • English
    Neural Models of Plasticity: Experimental and Theoretical Approaches is an outgrowth of a conference that was held at Woods Hole, Massachusetts, in the spring of 1987. The purpose of that conference was to review recent developments in both areas and to foster communication between those researchers pursuing theoretical approaches and those pursuing more empirical approaches. Contributions have been solicited from individuals who represent both ends of the spectrum of approaches as well as those using a combination of the two. These indicate that our knowledge of the plastic capabilities of the nervous system is accelerating rapidly due to rapid advances in the understanding of basic subcellular and molecular mechanisms of plasticity, and because of the computational capabilities and plastic properties that emerge from neural networks and assemblies. The book contains 19 chapters and opens with a study on the role of the neuromodulator in associative learning of the marine mollusk Hermissend. Subsequent chapters examine topics such as learning and memory in Aplysia; the Hebb rule for synaptic plasticity; olfactory processing and associative memory in the mollusk Limax maximus; simulation of a classically conditioned response; and the neural substrates of memory, focusing on the role of the hippocampus.

  • Neurosciences Research

    Volume 3
    • 1st Edition
    • S Ehrenpreis + 1 more
    • English
    Neurosciences Research, Volume 3 covers research problems concerned with the central nervous system. The book discusses the transport processes at the brain cell; the life history of the microglial cell; and studies on the choroid plexus. The text also describes the role of the cerebral peduncle in movements, as well as the pathobiological aspects of the action of tetanal toxin in the nervous system and skeletal muscle. Neuroscientists, neurochemists, and neuropathologists will find book useful.

  • Trophic Regulation of the Basal Ganglia

    Focus on Dopamine Neurons
    • 1st Edition
    • K. Fuxe + 2 more
    • English
    Trophic Regulation of the Basal Ganglia: Focus on Dopamine Neurons examines neurotransmitters. The book first discusses the role of fibroblast growth factor-2 (FGF-2) and ganglioside GM1 and the trophic regulation of the basal ganglia. Biochemical and histochemical studies on the cellular localization of FGF-2; mapping of FGF-2 and its receptors in the basal ganglia postnatally and adulthood; and mapping of the ganglioside GM1 distribution in the basal ganglia are presented. The text also explains glucocorticoid and estrogen effects on the nigrostriatal and mesolimbic dopaminergic systems; factors associated to dopaminergic cell death in Parkinson's disease; and compensatory mechanisms at dopamine D-2 receptors. The book also describes the effects of brain-derived neurotrophic factor on injured dopaminergic neurons; role of gangliosides and trophic factors in brain repair; and features of the trophic action of polyamines. The text also underscores the presence of interleukin-1 in the central nervous system; neuropeptides synthesis in astrocytes; and astrocytic kynurenines as modulators of dopaminergic function in the rat basal ganglia. The selection is a good source of information for readers wanting to study neurotransmitters.

  • Steroid Hormone Regulation of the Brain

    Proceedings of an International Symposium Held at the Wenner-Gren Center, Stockholm, 27-28 October 1980
    • 1st Edition
    • Kjell Fuxe + 2 more
    • English
    Steroid Hormone Regulation of the Brain focuses on the advancement of knowledge of the properties of brain steroid receptors and steroid target nerve cells, including the actions of gonadal steroids, adrenocortical steroids, and androgenic steroids on the brain. The selection features the work of authors who have inspiringly conducted extensive studies on the action of steroid hormones. The book starts with discussions that point out that steroid hormones not only function through intracellular steroid receptors, but possibly through steroid membrane actions as well. Studies to support this claim are presented. As to the action of steroid hormones on presynaptic transmitter mechanisms, the book suggests that adrenocortical and gonadal steroids can create alterations in noradrenaline, adrenaline, and dopamine levels and turnover within the hypothalamus and preoptic area. The effects of catecholestrogens on the brain are also elaborated. A contribution to this paper stresses that estrogens have antidopaminergic action in the extrapyramidal system. This idea is identified through a series of behavioral experiments and measurements of the levels of striatal acetylcholine. This selection is recommended to scientists interested in studying the effect of hormones on the brain.

  • Contributions to Contemporary Neurology

    A Tribute to Joseph Michael Foley
    • 1st Edition
    • Robert B. Daroff + 1 more
    • English
    Contributions to Contemporary Neurology features articles presented at the scientific meeting at the March 1986 gala evening affair held in Cleveland, Ohio in honor of neurologist Joseph Michael Foley's seventieth birthday and his impending transition to Professor Emeritus at Case Western University. This book is organized into 20 chapters written by 41 contributors. It starts with the biography of Foley and ends with his curriculum vitae. In between the biographies and curriculum vitae are basic and clinical articles written by professionals closely associated with Foley throughout his illustrious career. This book will be of interest to those interested in learning about the life and career of neurologist Joseph Michael Foley.

  • Neurotoxins

    • 1st Edition
    • Volume 8
    • P. Michael Conn
    • English
    The exquisite simplicity and potency of toxins have made them valuable probes of neural systems. This book presents a comprehensive compilation of techniques used for the preparation, handling, and, particularly, for the use of neurotoxins. Model systems are described in which these neurotoxins have been extremely valuable in developing an understanding of the cellular and molecular basis of secretion and electrophysiological events leading to altered cell function.

  • Topical Reviews in Neurosurgery

    Volume 1
    • 1st Edition
    • J. M. Rice Edwards
    • English
    Topical Reviews in Neurosurgery, Volume 1 focuses on neurosurgery, a medical specialty concerned with the prevention, diagnosis, treatment, and rehabilitation of disorders that affect any portion of the nervous system. This book discusses the advances in computed tomography, vascular surgery in neurological disorders, and carotid endarterectomy. The extracranial-intracr... anastomosis, etiology of chronic subdural hematoma, radical surgery in the treatment of craniopharyngiomas, and syringomyelia are also covered. Other topics include the sensory neural deafness; aneurysmal hemorrhage; detection of carotid stenosis; bypass procedures; and completed stroke in the carotid territory. This publication likewise considers the middle cerebral aneurysms; cell kinetics of glioma; and pathophysiology of enlargement of chronic subdural hematomas. This publication is a good source for neurosurgeons and medical students interested in neurosurgery.

  • Comparative Neurochemistry

    Proceedings of the Fifth International Neurochemical Symposium
    • 1st Edition
    • Derek Richter
    • English
    Comparative Neurochemistry, a collection of papers presented at the Fifth International Symposium of Comparative Neurochemistry, held at St. Wolfgang, Austria in 1962, deals with variations in neurochemical mechanisms in different animal species. The book integrates the data derived from comparative studies in different disciplines and assesses their significance in relation to the understanding of nervous mechanisms in animals, including human. The papers are grouped into sections, which cover general topics on functional organization in different species; lipids, proteins, and ribonucleic acid; amino acids in different species; energy metabolism and function; neurosecretory mechanisms; and comparative neuropharmacology. The text will be of interest to biologists, zoologists, pharmacologists, chemists, neurologists, and researchers in the pharmaceutical and chemical industries.

  • Infections of the Nervous System

    Butterworths International Medical Reviews
    • 1st Edition
    • Peter G. E. Kennedy + 1 more
    • English
    Infections of the Nervous System aims to continue the legacy of its predecessor, Modern Trends in Neurology. Its goal is to produce annually a monograph on a topic in clinical neurology in which progress through research has brought about new concepts of patient management. This book is organized into 13 chapters. It highlights the areas or subjects in which significant advances have been made which also have relevance to the treatment of patients. It covers a number of important aspects of different infectious diseases of the nervous system including acute bacterial meningitis, tuberculosis of the nervous system, spirochaetal infections of the nervous system, and fungal diseases of the central nervous system. This book is intended for use by physicians who deal with the problems of neurological disorder on a daily basis, whether they are neurologists, neurologists in training, or those in related fields such as neurosurgery, internal medicine, psychiatry, and rehabilitation medicine.

  • Lipid Metabolism in Signaling Systems

    • 1st Edition
    • Volume 18
    • P. Michael Conn + 1 more
    • English
    Many of the phospholipases and even the receptor for inositol 1,4,5-trisphosphate have recently been cloned and sequenced and play an important role in neurotransmission. Methods developed in recent years for the study of the enzymes and intermediates involved in the regulation of neuronal signal transduction involving phospholipid turnover are presented in this volume.

  • Neuropeptide Analogs, Conjugates, and Fragments

    Methods in Neurosciences, Vol. 13
    • 1st Edition
    • P. Michael Conn
    • English
    Methods in Neurosciences, Volume 13: Neuropeptide Analogs, Conjugates, and Fragments covers the synthesis and characterization of peptide analogs, conjugates, and fragments, their use as ligands for receptors, and their role in the development and use of antisera. The book discusses techniques such as novel synthetic approaches; biotinylation; purification and characterization; radioligand techniques and assay development; use of agonists and antagonists; distinguishing receptor subtypes; conjugation to carrier proteins; antiidiotypic antibody development; and radiolabeling. Neuroscientists, biochemists, neurochemists, and pharmacologists will find the book useful.

  • Neurochemistry of the Retina

    Proceedings of the International Symposium on the Neurochemistry of the Retina Held in Athens, Greece, August 28 - September 1, 1979
    • 1st Edition
    • Nicolas G. Bazan + 1 more
    • English
    Neurochemistry of the Retina covers the proceedings of the International Symposium on the Neurochemistry of the Retina held in Athens, Greece, on August 28 – September 1, 1979. This book mainly focuses on the retina and its neurochemistry. This text is divided into eight major parts. The first part discusses the composition, metabolism, and biogenesis of membrane components. This book then explains the biochemical approaches to the study of visual cells and their relationship with the pigment epithelium, photorector shedding, and circadian rhythm. Chemical transmission of nerve signals is also tackled. This text also looks into the biochemical aspects of photoreceptor structure and function; cyclic nucleotides; and biochemical and pharmacological approaches to study the entire retina. This book concludes by explaining the neurochemical studies in retinal diseases and future research and prospective of the subject. This publication will be invaluable to ophthalmologists and students of ophthalmology.

  • Aminopyridines and Similarly Acting Drugs: Effects on Nerves, Muscles and Synapses

    Proceedings of a IUPHAR Satellite Symposium in Conjunction with the 8th International Congress of Pharmacology, Paris, France, July 27-29, 1981
    • 1st Edition
    • P. Lechat + 2 more
    • English
    Aminopyridines and Similarly Acting Drugs: Effects on Nerves, Muscles and Synapses presents the proceedings of a IUPHAR Satellite Symposium in conjunction with the eighth International Congress of Pharmacology held in Paris, France on July 27-29, 1981. The book contains papers on the effects of aminopyridines on ionic currents in excitable membranes; the effects of aminopyridines on synaptic transmission; and the effects of aminopyridines on the release of chemical transmitters. The text also presents papers on some differences in the blockade of potassium permeabilities by apamin and the aminopyridines; the miscellaneous actions of aminopyridines and related compounds; and the effects of aminopyridines on the skeletal, smooth and cardiac muscle. The clinical applications of aminopyridines and further miscellaneous actions of aminopyridines and related compounds are also considered.

  • Progress in Behavior Modification

    Volume 2
    • 1st Edition
    • Michel Hersen + 2 more
    • English
    Progress in Behavior Modification, Volume 2 reviews issues and developments in the field of behavior modification, with emphasis on a wide spectrum of child and adult disorders. Topics covered range from behavioral assessment and treatment of alcoholism to sexual arousal in male sexual deviates, along with aversion therapy and research methods in behavior modification. Comprised of eight chapters, this volume begins with a discussion on the status and future trends in behavior assessment of alcoholism and behavior modification with alcoholics. The next chapter deals with therapy models, focusing on the domain of social learning, removal of fears, and assertive and social skill training. The discussion then turns to the measurement and generation of sexual arousal in male sexual deviates; applications of behavior modification in nursing practice; aversion therapy and its clinical effects; deceleration of aberrant behavior among retarded individuals; and research methods in behavior modification. The final chapter examines clinical issues regarding behavioral self-control. This book should be of value to theoreticians, researchers, or practitioners in the fields of psychiatry, psychology, and behavior therapy as well as social work, speech therapy, education, and rehabilitation.

  • Biochemistry of Brain

    • 1st Edition
    • Sudhir Kumar
    • English
    Biochemistry of Brain is a collection of articles dealing with the developments in the biochemistry of the brain. This book gives a comprehensive and critical discussion of important developments in studies concerning the above subject. This text discusses the structure, function, and metabolism of glycosphingolipids, which are related to the study of sphingolipid storage diseases. Inborn defects of metabolism are found in Gaucher's and Fabry's disease, which are characterized by lipid accumulation in the brain. Another paper reviews the chemical and genetics of critically lysosomal hydrolase deficiencies that can cause the storage of sphingolipids. This book then explains the role of myelin basic protein in lipids in vivo that the weak bonding of the protein is not a major component of myelin stability. Another paper discusses the procedures for isolating subfractions of myelin and myelin-related membranes, with some attention given on the alterations in the subfractionation of myelin in pathological hypomyelinating and demyelinating conditions. Another article discusses the biochemical and enzymatic composition of lysosomes and the biosynthesis, intracellular transport, storage, and the degradation of lysosomal constituents. This collection of papers will benefit scientists doing research in microbiology, microchemistry, molecular genetics, and neurochemistry.

  • Neuromuscular Function and Disorders

    • 1st Edition
    • Alan J. McComas
    • English
    Neuromuscular Function and Disorders focuses on the various processes underlying disordered neuromuscular function. Topics covered include the nature of membrane defects in myotonia and familial periodic paralysis; the disorder of neuromuscular transmission responsible for myasthenia gravis and the various pseudo-myasthenic syndromes; and the disorders of Schwann cell function which cause demyelination. This book is comprised of 28 chapters divided into two sections and begins with a discussion on the normal anatomy and physiology of peripheral nerve and muscle. Included in the first section are descriptions of the ionic mechanisms responsible for the resting and action potentials of nerve and muscle; the sequential stages in neuromuscular transmission; excitation-contracti... coupling; the sliding filament mechanism of myofibrillar shortening; and the morphological and functional properties of motor units. The neurophysiology of exercise and muscle fatigue is also considered, along with the nature of the trophic influences exerted by the motoneuron and muscle fiber upon each other. The second half of the book deals entirely with various diseases of peripheral nerve and muscle, together with diagnostic procedures and therapeutic management. A consistent theme in this section is the recognition of neural abnormalities in diseases hitherto considered as primary disorders of the muscle fiber. This monograph should be of value to neurologists, medical students, research workers, and students and research scientists in physiology, zoology, pharmacology, kinesiology, and physical education.

  • Receptors in the Human Nervous System

    • 1st Edition
    • F. A. O. Mendelsohn + 1 more
    • English
    Receptors in the Human Nervous System is a synthesis of the results of receptor mapping by leaders in the field. In addition to a comprehensive discussion of the distribution and possible interactions of the receptors of different neuroactive substances, this book also contains an abundance of pictorial representations of receptor distributions. High-quality photographs of one receptor are often juxtaposed with photographs of the distribution of a different receptor or receptor subtype for the consideration of possible interactions between different systems. The book surveys the distribution of receptor subtypes for the classical monoamine transmitters (acetylcholine, adrenaline, noradrenaline and serotonin) as well as the distribution of receptors for the excitatory and inhibitory amino acids, (glutamate, GABA and benzodiazepines) as well as the opioid peptides, angiotensen and other neuropeptides. The distribution of multiple types of serotonin receptors is given in detail, and the codistribution of receptors in the cortex is discussed. The book is directed toward researchers in the field of chemical neuroanatomy, as well as pharmacologists, neurophysiologists, and neuroscientists.

  • Biological Aspects of Affective Disorders

    • 1st Edition
    • Volume 1
    • R.W. Horton
    • English
    Biological research in the affective disorders has been an international growth industry for several years. Biological Aspects of Affective Disorders is a comprehensive introduction to the biochemical, pharmacological, and genetic aspects constituting the abnormalities that may underline the diseases of depression and mania, together with the current understanding of the clinical features and management of affected patients.It will be of great value especially to young researchers from all disciplines contributing to this area and to trainee psychiatrists.

  • Using Secondary Datasets to Understand Persons with Developmental Disabilities and their Families

    • 1st Edition
    • Volume 45
    • English
    International Review of Research in Developmental Disabilities is an ongoing scholarly look at research into the causes, effects, classification systems, syndromes, etc. of developmental disabilities. Contributors come from wide-ranging perspectives, including genetics, psychology, education, and other health and behavioral sciences.

  • Readings in Cognitive Science

    A Perspective from Psychology and Artificial Intelligence
    • 1st Edition
    • Allan Collins + 1 more
    • English
    Readings in Cognitive Science: A Perspective from Psychology and Artificial Intelligence brings together important studies that fall in the intersection between artificial intelligence and cognitive psychology. This book is composed of six chapters, and begins with the complex anatomy and physiology of the human brain. The next chapters deal with the components of cognitive science, such as the semantic memory, similarity and analogy, and learning. These chapters also consider the application of mental models, which represent the domain-specific knowledge needed to understand a dynamic system or natural physical phenomena. The remaining chapters discuss the concept of reasoning, problem solving, planning, vision, and imagery. This book is of value to psychologists, psychiatrists, neurologists, and researchers who are interested in cognition.

  • Tissue Engineering of the Peripheral Nerve: Biomaterials and Physical Therapy

    • 1st Edition
    • Volume 109
    • English
    This issue of International Review of Neurobiology brings together cutting-edge research on tissue engineering of the peripheral nerve. It reviews current knowledge and understanding, provides a starting point for researchers and practitioners entering the field, and builds a platform for further research and discovery.

  • Tissue Engineering of the Peripheral Nerve

    Stem Cells and Regeneration Promoting Factors
    • 1st Edition
    • Volume 108
    • English
    This issue of International Review of Neurobiology brings together cutting-edge research on tissue engineering of the peripheral nerve. It reviews current knowledge and understanding, provides a starting point for researchers and practitioners entering the field, and builds a platform for further research and discovery.

  • Hysteria and Related Mental Disorders

    An Approach to Psychological Medicine
    • 1st Edition
    • D. Wilfred Abse
    • English
    Hysteria and Related Mental Disorders: An Approach to Psychological Medicine deals with the problems of diagnosis and their bearing on management and treatment of hysteria and related hysteriform conditions. This book is composed of 16 chapters, and starts with a description of the etiology and psychopathology of hysteria. These topics are followed by intensive discussions on the clinical manifestations and diagnosis of hysteria and related mental disorders, including neurosis, psychosis, schizophrenia, and multiple personality. Other chapters consider the nature of dissociative phenomena from a structural and dynamic point of view, as well as its significance in understanding the etiology of ego disorders. This book also looks into some aspects of language development, the conversion process, and the features of hysteria as a communicative disorder. The last chapters present several medical cases illustrating the differences between conversion hysteria and psychophysiologic autonomic disorder. These chapters also deal with the types of psychotherapy for hysteria. This book is of great value to psychologists, neurologists, clinicians, and psychotherapists.

  • The Choroid Plexus in Health and Disease

    • 1st Edition
    • Martin G. Netsky + 1 more
    • English
    The Choroid Plexus in Health and Disease is a collection of data and information elucidating the normal structure and function, and the clinical disorders of the choroid plexus in relation to embryology, anatomy, chemistry, and physiology. The book contains articles that discuss topics on the origin of choroid plexus and ependyma; normal structure of choroid plexus; physiology of the choroid plexus; heterotopic choroid plexus and ependyma; traumatic disorders and their effect on choroid plexus and ependyma; and metastatic tumor in the choroid plexus. Physiologists, neurologists, anatomists, teachers, and students in the medical field will find the book invaluable.

  • Brain Preparations

    By Means of Defibrillation or Blunt Dissection: A Guide to the Macroscopic Study of the Brain
    • 1st Edition
    • J. Wilh. Hultkrantz
    • English
    Brain Preparations by means of Defibrillation or Blunt Dissection: A Guide to the Macroscopic Study of the Brain presents a critical review of anatomical facts and preparation of brain specimens. The book discusses the techniques and the principles of the defibrillation method, as well as the splitting properties of the hardened brain to show its structure. Some of the topics covered in the text are the preparation of a half-brain according to the defibrillation method; the outer form, soft membranes, nerves and vessels of the brain; and the description of the white substance of the cerebrum, association fibres, corpus callosum, and brain ventricles. The structure of the nucleus caudatus and thalamus; the preparation of the outer form of the rhombencephalon and ventricle; and the description of supplementary preparations on a half-brain are discussed. The book further presents the investigation made on the pallium, ventricles, and its structures; and the parts of the brain stem. A chapter is devoted to photographic illustrations of preparations made on the brain using defibrillation method. The book can provide useful information to neurosurgeons, doctors, students, and researchers.

  • Neuro-psychopharmacology

    Proceedings of the Tenth Congress of the Collegium Internationale Neuro-Psychopharmacologicum Québec, July 4-9, 1976
    • 1st Edition
    • P. Deniker
    • English
    Neuro-psychopharmaco...

  • The Fine Arts, Neurology, and Neuroscience

    Neuro-Historical Dimensions
    • 1st Edition
    • Volume 203
    • English
    This well-established international series examines major areas of basic and clinical research within neuroscience, as well as emerging and promising subfields. This volume explores the history and modern perspective on neurology and neuroscience.

  • Noise and the Brain

    Experience Dependent Developmental and Adult Plasticity
    • 1st Edition
    • Jos J. Eggermont
    • English
    In our industrialized world, we are surrounded by occupational, recreational, and environmental noise. Very loud noise damages the inner-ear receptors and results in hearing loss, subsequent problems with communication in the presence of background noise, and, potentially, social isolation. There is much less public knowledge about the noise exposure that produces only temporary hearing loss but that in the long term results in hearing problems due to the damage of high-threshold auditory nerve fibers. Early exposures of this kind, such as in neonatal intensive care units, manifest themselves at a later age, sometimes as hearing loss but more often as an auditory processing disorder. There is even less awareness about changes in the auditory brain caused by repetitive daily exposure to the same type of low-level occupational or musical sound. This low-level, but continuous, environmental noise exposure is well known to affect speech understanding, produce non-auditory problems ranging from annoyance and depression to hypertension, and to cause cognitive difficulties. Additionally, internal noise, such as tinnitus, has effects on the brain similar to low-level external noise.Noise and the Brain discusses and provides a synthesis of hte underlying brain mechanisms as well as potential ways to prvent or alleviate these aberrant brain changes caused by noise exposure.

  • The Fine Arts, Neurology, and Neuroscience

    New Discoveries and Changing Landscapes
    • 1st Edition
    • Volume 204
    • English
    This volume on neuroscience, neurology, and the fine arts brings several disciplines together. It presents current thoughts and modern examples about how science, medicine and the arts have interacted in the past and are still converging. This volume specifically explores the history and modern perspective on neurology and neuroscience.

  • Catecholamines: Basic and Clinical Frontiers

    Proceedings of the Fourth International Catecholamine Symposium, Pacific Grove, California, September 17-22, 1978
    • 1st Edition
    • Earl Usdin
    • English
    Catecholamines: Basic and Clinical Frontiers is a collection of papers that discusses clinical problems related to this series of compounds which includes dopamine, epinephrine, and norepinephrine. One paper discusses the role of biogenic amines in several mental disorders, such as senile dementia, schizophrenia, chronic alcoholism, and affective disorders. Another paper describes that in studies of mice, the number of neurotransmitter-spe... neurons is under a genetic control and can be a significant determinant of species-dependent variation in brain chemistry, nuclear organization, drug responses, and spontaneous behavior. One paper investigates if prostaglandins can directly alter the release or reuptake of catecholamines in the central nervous system, as well as their action upon the disposition of different metabolites of dopamine and norepinephrine in brain perfusate. The effects of several drugs on shock elicited fighting in rats show no significant aspects with amphetamine, apomorphine, phenoxybenzamine or phentolamine. The use of clonidine and propranolol shows a significant inhibition of fighting, while low doses of piperoxane exhibits a marked increase in fighting behavior. The collection can prove beneficial for pharmacologists, biochemists, micro-biologists, cellular researchers, and academicians involved in the study of physiology or neuroendocrinology.

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