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Elsevier

Books in Organic chemistry

This collection offers extensive coverage of organic synthesis, reaction mechanisms, and functional group chemistry. Showcasing innovative research, green chemistry approaches, and industrial applications, it supports chemists, students, and researchers in designing new molecules and materials. Addressing drug discovery, polymers, and sustainable processes, these titles foster creativity and technical excellence in advancing organic chemistry for societal benefit.

  • Studies in Natural Product Chemistry

    • 1st Edition
    • Volume 76
    • Atta-ur Rahman
    • English
    Natural products in the plant and animal kingdom offer a huge diversity of chemical structures that are the result of biosynthetic processes that have been modulated over the millennia through genetic effects. With the rapid developments in spectroscopic techniques and accompanying advances in high-throughput screening techniques, it has become possible to isolate and then determine the structures and biological activity of natural products rapidly, thus opening up exciting opportunities in the field of new drug development to the pharmaceutical industry. Studies in Natural Products Chemistry covers the synthesis or testing and recording of the medicinal properties of natural products, providing cutting edge accounts of the fascinating developments in the isolation, structure elucidation, synthesis, biosynthesis and pharmacology of a diverse array of bioactive natural products.

  • Medicinal Chemistry of Anticancer Drugs

    • 3rd Edition
    • Carmen Avendaño + 1 more
    • English
    This third edition of Medicinal Chemistry of Anticancer Drugs, provides an updated resource for students and researchers from the point of view of medicinal chemistry and drug design, focusing on the mechanism of action of antitumor drugs from the molecular level, and on the relationship between chemical structure and chemical and biochemical reactivity of antitumor agents. Antitumor chemotherapy is a very active field of research, and a huge amount of information on the topic is generated every year. This new edition includes updated sections on the hot topic of cancer immunotherapy, cancer polypharmacology, multitargeted cancer therapy, medicinal chemistry of cancer diagnosis, theranostic anticancer agents, and pre-mRNA processing in cancer. Although many books are available that deal with clinical aspects of cancer chemotherapy, this book provides a unique and valuable perspective from the point of view of medicinal chemistry and drug design. It will be useful to undergraduate and postgraduate students of medicinal chemistry, pharmacology, biological chemistry, pharmacy and other health sciences. Researchers and practitioners will find a comprehensive treatment of the topic and a large number of references to reviews and the primary literature.

  • Recent Frontiers of Phytochemicals

    • 1st Edition
    • Siddhartha Pati + 2 more
    • English
    Phytochemicals have been present in human diet and life since the birth of mankind, including the consuming of plant foods and the application of herbal treatments. This coevolutionary interaction of plants and people has resulted in humans' reliance on food and medicinal plants as sources of macronutrients, micronutrients, and bioactive phytochemicals. Phytochemicals can be used as adjuvant agents and sensitizers in traditional antibiotic and anticancer therapy, reducing the potential of selecting resistant microbial strains and cancer cells. Recent Frontiers of Phytochemicals addresses the many processes of potential phytochemical evaluation of known sources, with a focus on phytochemical and pharmacological evaluations, and computational research into the structures and pharmacological mechanisms of natural products and their applications in medicine, food and biotech.

  • Advances in Heterocyclic Chemistry

    • 1st Edition
    • Volume 140
    • Eric F.V. Scriven + 1 more
    • English
    Advances in Heterocyclic Chemistry, Volume 140 is the latest release in this definitive series in the field of heterocyclic chemistry, one of great importance to organic chemists, polymer chemists, and many biological scientists. Written by established authorities in the field from around the world, this comprehensive review combines descriptive synthetic chemistry and mechanistic insight to yield an understanding of how chemistry drives the preparation and useful properties of heterocyclic compounds. Chapters in this new release include The chemistry of citrazinic acid (2,6-dihydroxyisonic... acid), Aza-Diels-Alder Reaction in the Synthesis of Tetrahyroquinoline Structures, and more. Additional chapters delve into Recent Developments in the Synthesis of 4-, 5-, 6- and 7-Azaindoles, Fluoroheterocycle formation using fluoroalkynes and their synthetic equivalents, Advances in applications of dihydropyridines in organic chemistry, and Recent Developments in the Chemistry of Triphyrins (2.1.1).

  • Oxetane Synthesis

    • 1st Edition
    • Navjeet Kaur
    • English
    Oxetane Synthesis rings play an important role as versatile motifs both in the overall formation of natural products and in synthetic organic chemistry. Oxetanes are important motifs in pharmaceutical chemistry that can confer improved metabolic and physicochemical properties. These developments continue to enhance the use of oxetanes in medicinal chemistry. Thanks to the growing commercial accessibility of oxetane possessing building blocks, together with improved approaches for the formation, oxetanes are likely to be progressively utilized in medicinal chemistry programs. Oxetanes are becoming valuable as a result of their vast diversity of uses in medicinal chemistry and varying applications. Several procedures have been developed for the formation and ring-opening of oxetanes to give important compounds in agrochemical, medicinal and material sciences. Novel approaches have been developed for the synthesis of oxetanes. These methods depend on both established synthetic approaches and development of many novel approaches for the formation of oxetanes.

  • Nanoparticles in Green Organic Synthesis

    Strategy towards Sustainability
    • 1st Edition
    • Sabyasachi Bhunia + 4 more
    • English
    Nanoparticles in Green Organic Synthesis: Strategy towards Sustainability presents the fundamental and latest practical uses of metal nanoparticles (MNPs) in organic synthesis, as well as their promising multidimensional applications. The book examines the latest emerging research on MNP synthesis and their applications—from organic transformation to energy and the environment—allowing readers to critically analyze the role of different MNPs in seeking ideas for widespread application. The book covers the fundamentals while also providing a comprehensive account of MNPs and their modification for a variety of green platform-based derivatives, focusing on the multifunctional technological evolution. The book covers a wide range of applications in organic synthesis using a variety of transition-metal-bas... nanoparticles in both homo- and heterogeneous media. The text details the concept of catalyst design and recent developments in the preparation and characterization of nanomaterials, followed by several chapters on the design of catalysts for specific applications. This volume is a valuable resource for those working in green chemistry, sustainability, material science and engineering, nanotechnology, energy, and the environment.

  • Marine Phenolic Compounds

    Science and Engineering
    • 1st Edition
    • Jose Ricardo Perez Correa + 2 more
    • English
    Marine Phenolic Compounds: Science and Engineering is a comprehensive resource on these secondary metabolites. Phenolic compounds are secondary metabolites with increasing scientific, commercial and general population interest for their wide distribution, variety and potential applications Less studied than terrestrial sources, marine organisms contain highly interesting phenolic compounds due to their exclusive structures. In addition, the distinctive features of the marine solid matrix, requires novel process technology approaches. The high productivity of marine biomass makes it a renewable source of valuable components with potential for commercial applications.

  • Iodine-Assisted Synthesis of Six- and Seven-Membered Heterocycles

    • 1st Edition
    • Navjeet Kaur
    • English
    Iodine-Assisted Synthesis of Six- and Seven-Membered Heterocycles covers both existing and the latest methods for the synthesis of various six- and seven-membered heterocycles using iodine. Covering an important and rapidly growing branch of heterocyclic chemistry, this book allows users easy access to the synthetic protocols for the synthesis of heterocycles, acting as a guide for how to make these important compounds employed as agrochemicals, pharmaceuticals, and veterinary products, using particular reagents. This book will be of interest to students, pharmacologists, biochemists, and organic and medicinal chemists.

  • Advances in Heterocyclic Chemistry

    • 1st Edition
    • Volume 139
    • Eric F.V. Scriven + 1 more
    • English
    Advances in Heterocyclic Chemistry, Volume 139, the latest release in this definitive series on the field of heterocyclic chemistry, combines descriptive synthetic chemistry and mechanistic insights to yield an understanding on how chemistry drives the preparation and useful properties of heterocyclic compounds. Topics in this new release include Application of the Fischer indole synthesis in medicinal chemistry, Oxindole Synthesis via C-H Activation Methods, Ring-Closing Metathesis in the Synthesis of Fused Indole Structures, Synthesis of fuller heterocycles, The Literature of Heterocyclic Chemistry, Part XX, 2020, and Heterocyclic Zwitterions Based on Coupled Polymethines.

  • The Alkaloids

    • 1st Edition
    • Volume 89
    • Hans-Joachim Knolker
    • English
    The Alkaloids, Volume 89, the newest release in a series that has covered the topic for more than 60 years, discusses key aspects of alkaloid chemistry, biology and pharmacology. Sections in this release include chapters on Recent Progress in the Chemistry of Naphthylisoquinoline Alkaloids, The Biological Activities of Quinolizidine Alkaloids, and C NMR Spectral Data and Pharmacological Activities of Aporphine Alkaloids.

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