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Books in Life sciences

  • Animal Models of Disease Part A

    • 1st Edition
    • Volume 185
    • English
    Animal Models of Disease, Part A, Volume 185 in the Methods in Cell Biology series, highlights advances in the field, with this new volume presenting interesting chapters on a variety of timely topics, including New mouse model to study aneurysm development, Mouse Model of Secondary Cystic Echinococcosis, Modelling childhood cancer in Drosophila, Analysis of immunohistomorpholog... changes in the colonic mucosa in a high-saturated fat and high-cholesterol fed streptozotocin/nicot... diabetic rat model, Establishment of an orthotopic Glioblastoma mouse model for preclinical studies, Lateral Fluid Percussion Injury as a Model for Traumatic Brain Injury, Ovarian and colorectal peritoneal carcinomatosis in mouse models, and more.Other chapters cover Genetically engineered mouse model of hepatocellular carcinoma, Radiotherapy protocol in cancer mouse models, Using C. elegans as a model for neurodegenerative diseases: Methodology and evaluation, Methodology for the induction of myocardial infarction and cardiac function evaluation, Behavioral assessment of fine socio-sexual olfactory cues detection in a mouse model of neurodegeneration, Heat shock and thermotolerance in Caenorhabditis elegans: an overview of laboratory techniques, and Using the model cestode Taenia crassiceps for the study of cysticercosis.

  • The neurobiology of Alcohol Use Disorder

    Neuronal mechanisms, current treatments and novel developments
    • 1st Edition
    • Volume 175
    • English
    The Mechanisms Behind Developing Dependence, Sub-groups, and Novel Approaches to Treatment, Volume 174 in the Neurobiology of Alcohol Abuse series, highlights new advances in the field, with this new volume presenting interesting chapters on topics such as Substitution therapy in alcohol treatment, with a focus on mechanisms and possibilities, Designing and analyzing studies on treatments for alcohol dependence, The harm reduction approach for treatment of alcohol dependence, Current treatments for alcohol dependence, with a suggested focus on mechanisms and possibilities, Metabolomics in relation to alcohol dependence with focus on possibilities for precision medicine, and Repurposing drugs for treatment of alcohol dependence.

  • From Brain Dynamics to the Mind

    Spatiotemporal Neuroscience
    • 1st Edition
    • Georg Northoff
    • English
    From Brain Dynamics to the Mind: Spatiotemporal Neuroscience explores how the self and consciousness is related to neural events. Sections in the book cover existing models used to describe the mind/brain problem, recent research on brain mechanisms and processes and what they tell us about the self, consciousness and psychiatric disorders. The book presents a spatiotemporal approach to understanding the brain and the implications for artificial intelligence, novel therapies for psychiatric disorders, and for ethical, societal and philosophical issues. Pulling concepts from neuroscience, psychology and philosophy, the book presents a modern and complete look at what we know, what we can surmise, and what we may never know about the distinction between brain and mind.

  • Heart Development and Disease

    • 1st Edition
    • Volume 156
    • English
    Heart Development and Disease, Volume 156 in the Current Topics in Developmental Biology series, highlights new advances in the field, with this new volume presenting interesting chapters including Macrophages during heart valve development, Computational models of cardiovascular biology, Mechanisms of early sarcomere assembly, Role of RNA binding proteins during heart development and disease, Early heart development and morphogenesis, PSC models for development and disease, ECM or SHF development, Role of metabolism during heart development, Cellular ploidy in cardiac biology, and Genetics of CHD in the human population.

  • Microbial Technology for Agro-Ecosystems

    Crop Productivity, Sustainability, and Biofortification
    • 1st Edition
    • Vivek Kumar + 1 more
    • English
    Microbial Technology for Agro-Ecosystems: Crop Productivity, Sustainability, and Biofortification describes the application of competent microbes in plant growth promotion, nutrient management and recycling from molecular perspectives. Understanding of molecular mechanism of Microbial diversity in association with plant roots is very imperative for plant health and ecosystem equilibrium.

  • Public Health and Toxicology Issues in Drug Research, Volume 2

    Toxicity and Toxicodynamics
    • 1st Edition
    • Rakesh Kumar Tekade + 1 more
    • English
    Public Health and Toxicology Issues in Drug Research: Toxicity and Toxicodynamics, Volume Two examines implications on public health and the impact of pharmaceuticals, chemical and food toxicants, dietary phytochemicals, and medical treatments. The book cover topics on pharmacokinetics and toxicokinetics, such as population pharmacokinetics/tox... the design of toxicokinetic studies, and the use of toxicokinetic data in preclinical safety assessments. In addition, it investigates the health effect caused by the bioaccumulation of pharmaceutical and personal care products and the impact of drug-induced toxicity on different systems of the body.Final sections discuss the mechanistic pathways of food toxicants and illustrate the molecular mechanisms of the chemopreventive role of dietary phytochemicals. Ethical, legal, societal, and professional issues in toxicology round off coverage, making this a valuable resource for anyone interested in learning more about the health impact and public health issues related to the toxicity of pharmaceuticals, dietary supplements, personal care products, and medical treatments.

  • Emerging Contaminants

    Sustainable Agriculture and the Environment
    • 1st Edition
    • Arpna Kumari + 4 more
    • English
    Emerging Contaminants: Sustainable Agriculture and the Environment provides a thorough, comprehensive, and interdisciplinary overview of the many categories of emerging pollutants, including pharmaceuticals, insecticides, personal care items, and industrial chemicals, that are currently impacting the environment. With insights into the exposure associated consequences on crops and edible plants, this book is designed to enable foundational understanding as the basis for future research, as well as providing practical application guidance in current environments.Water resource shortages, declining arable land, environmental contamination with different exiting or ECs, shortcomings in the procedures for protecting cultivated land, and inefficiencies in the management of land tenure rights continue to pose challenges for agricultural sustainable development around the world. This book focuses on the impacts of ECs on sustainable agricultural production and explores possible response approaches.Following an introduction to environmental contaminants, this book discusses their fate in soils, presents the most up-to-date analytical methods for detecting them in different environmental matrices, and addresses current regulatory restrictions. Finally, this book ends with a chapter dedicated to conclusions and future perspectives.Emergin... Contaminants is an ideal resource for researchers and professionals from a variety of sciences including agricultural, plant, and environmental.

  • Molecular Impacts of Nanoparticles on Plants and Algae

    • 1st Edition
    • Huseyin Tombuloglu + 4 more
    • English
    Molecular Impacts of Nanoparticles on Plants and Algae covers molecular mechanisms of plants/algae related to cellular uptake, translocation of nanoparticles, and genome, transcriptome, proteome, and metabolome responses against it. The book introduces readers to state-of-the-art developments and trends of nanoparticles and plants/algae including interactions of nanoparticles with biological compounds in vitro. Nanoscience and nanotechnology have rapidly been developed in the last few decades, and they have a wide range of applications in industry, medicine, food, and agriculture. In agriculture, nanoparticles (NPs) have successfully been used for growth regulation, crop protection and improvement. This book presents the most recent findings on nanoparticle and plant/algae interaction by focusing on molecular response mechanisms at genome, transcriptome, proteome and metabolome levels. In addition, uptake and translocation mechanism of nanoparticles are assessed both in plant and algae. Throughout this book, the latest developments and discoveries are highlighted, along with open problems and future challenges in molecular mechanisms of plants/algae as a response of nanoparticles.

  • Treatise on Estuarine and Coastal Science

    • 2nd Edition
    • Daniel Baird + 1 more
    • English
    Treatise on Estuarine and Coastal Science, Seven Volume Set is the most up-to-date reference work for system based coastal and estuarine ecosystem science and management. It addresses the big issues facing the estuaries and coastal zone; in particular how to best use multi- and inter-disciplinary science to ensure the sustainability of the environment. It focusses on the need to protect and maintain the natural functioning of the estuaries and coasts worldwide while delivering the ecosystem services from which society extract goods and benefits.Structured chapters, written by leaders in the field, include reference lists and additional reading, copious diagrams, case-studies, and especially provide synthesis diagrams and conceptual models of complex issues. The Treatise covers both the natural and social sciences, serving a wide audience which ranges from undergraduate students to established researchers and practitioners. The work avoids autecological studies but focusses on inter-linked physical-chemical-bi... processes and associated socio-economic issues in the coastal zone. It examines estuaries and coasts, and their interactions and feedbacks with humanity, from the inland catchment/river basin to the ocean shelf.The new edition builds on and expands the previous version with significant updates and a whole new section on Climate Change and Coastal Ecosystems, covering the resistance and resilience of the estuaries, coasts and other transitional habitats to climate change, thereby determining changes and responses needed over the coming decades.

  • Advanced Vaccination Technologies for Infectious and Chronic Diseases

    A guide to Vaccinology
    • 1st Edition
    • Vasso Apostolopoulos + 2 more
    • English
    Advanced Vaccination Technologies for Infectious and Chronic Diseases is a comprehensive guide that delves into the intricate details of vaccine design, development across various platforms, and the path to commercialization. This book provides an introductory overview of vaccines, covering various types, developmental methodologies, delivery systems, adjuvants, immunization, and measurement of vaccine efficacy. It also showcases examples of vaccine research efforts targeting infectious diseases, autoimmune disorders, and cancer. The book concludes by exploring cutting-edge advances in proteogenomics, immunopeptidomics, and future vaccine technologies.The primary objective of this book is to inform a broad scientific audience about the fundamental concepts underlying vaccine and immunology. Further, it serves as an invaluable reference for understanding the critical steps in the journey from discovery to regulatory processes for human clinical trials, addressing common misconceptions and presenting factual information about vaccinations. Advanced Vaccination Technologies for Infectious and Chronic Diseases is a requisite reference for occupational health professionals whose roles involve supervision of immunization programs such as those working within the National Health Service, some sectors of higher education, or the pharmaceutical industry. It also caters to those researchers engaged in vaccine development and all who want to learn the processes involved from laboratory research to final product.

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