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Books in Life sciences

  • African Plant-Based Products as a Source of Potent Drugs to Overcome Cancers and their Chemoresistance

    Part 1. Cancer Chemoresistance, Screening Methods, and the Updated cut-off Points for the Classification of Natural Cytotoxic Products
    • 1st Edition
    • Volume 111
    • English
    African Plant-Based Products as a Source of Potent Drugs to Overcome Cancers and their Chemoresistance: Part One: Cancer Chemoresistance, Screening, Methods, and the Updated cut-off Points for the Classification of Natural Cytotoxic Products, Volume 111 offers an overview of the potential of African medicinal plants as a source of anticancer agents to overcome with an emphasis on cancer drug resistance. Based on the collected data, the book also offers a rational classification basis for the cytotoxic activity of natural products. The general knowledge of state-of-the-art of cancer drug resistance globally and the screening methods for cytotoxic agents are described.This book clearly identifies the best African medicinal plants that could be useful for the development of efficient herbal drugs, as well as the best phytochemicals that could be explored as potential pharmaceuticals to efficiently tackle cancers and their refractory phenotypes. The book appears a unique tool for Scientists for anticancer drug discovery from the exceptional flora of Africa.

  • Peptide and Peptide Mimicking Tools: Methods, Synthesis, Design & Applications

    • 1st Edition
    • Volume 698
    • English
    Peptide Chemical Tools for Modulating Biology, Volume 698 in the esteemed Methods in Enzymology series, highlights new advances in the field, with this new volume presenting interesting topics on Peptide tools that target telomere maintenance, Molecular Design of Peptide Therapeutics, Sulfonyl peptide tools for modulating biology, Peptide tools for targeting the Crk/CrkL-p130Cas axis, Quorum sensing peptide tools, In vivo stability and BBB penetration of peptide tools, and Oligo-benzamide-base... peptide mimicking tools for modulating biology.

  • Biomechanics of the Aorta

    Modeling for Patient Care
    • 1st Edition
    • T. Christian Gasser + 2 more
    • English
    As biomechanics is fundamental to understanding the normal and pathological functions of the aorta, Biomechanics of the Aorta presents a holistic analysis of aortic physiology, clinical imaging, tissue and blood flow modeling. It investigates a wide range of topics from basic sciences (vascular biology, continuum mechanics, image analysis) to essential knowledge for clinical applications, including diagnostics, aortic rupture prediction, as well as surgical planning. Expert chapter authors describe and present computational studies and experimental benches, to mimic, understand and propose the best treatment of aortic pathologies.Divided into five parts, the book begins with an introduction to the fundamental aspects of the anatomy, biology, and physiopathology of the aorta, and then proceeds to present concepts of imaging and tissue/rheology characterization, tissue modeling and rupture, and flow modeling and algorithms. The final part dives into applications and case studies including transcatheter aortic valve implantation, aortic aneurysm rupture prediction, aortic dissections, and pharmacological treatments.

  • The History of Gynecological Treatment of Women’s Pelvic Pain and the Recent Emergence of Pain Sensitization

    • 1st Edition
    • John F. Jarrell
    • English
    **2025 PROSE Award Finalist in Biomedicine and Neuroscience**The History of Gynecological Treatment of Women’s Pelvic Pain and the Recent Emergence of Pain Sensitization is a historical account on how women have been treated for the problems of pelvic pain. It describes the earliest reports of women suffering from pelvic pain that seem to suggest the presence of something beyond any understanding prior to the late twentieth century. This book is for awareness of the condition and will help readers understand the complex presentations of pelvic pain: the shift from episodic to persistent pain, referred pain, pain from a non-painful stimulus (allodynia), and excessive pain from a painful stimulus (hyperalgesia).This is a novel reference that provides a detailed chronology of past treatments and how the absence of awareness of pain sensitization led to some disreputable surgical procedures. In addition, it is an historical analysis on the emergence of central pain sensitization as an explanation for the historical challenges of the past to current developments.

  • Advances in Virus Research

    • 1st Edition
    • Volume 119
    • English
    Advances in Virus Research, Volume 119, the latest release in this esteemed series, presents the latest research and developments in viruses.

  • Computational and Network Modeling of Neuroimaging Data

    • 1st Edition
    • Kendrick Kay
    • English
    Computational and Network Modeling of Neuroimaging Data provides an authoritative and comprehensive overview of the many diverse modeling approaches that have been fruitfully applied to neuroimaging data. As neuroimaging is witnessing a massive increase in the quality and quantity of data being acquired, this book gives an accessible foundation to the field of computational neuroimaging, suitable for graduate students, academic researchers, and industry practitioners who are interested in adopting or applying model-based approaches in neuroimaging.It is widely recognized that effective interpretation and extraction of information from complex data requires quantitative modeling. However, modeling the brain comes in many diverse forms, with different research communities tackling different brain systems, different spatial and temporal scales, and different aspects of brain structure and function. This book takes a critical step towards synthesizing and integrating across different modeling approaches.

  • Human Neuroanatomy

    • 1st Edition
    • Reha Erzurumlu + 2 more
    • English
    Human Neuroanatomy is a unique resource that presents the neuroanatomy of the central and peripheral nervous systems. This atlas-style reference features human brain sections with radiological correlations and original illustrations accompanying macroscopic and microscopic photographs. Chapters include a large number of illustrations in the form of photographs, Illustrations, and MR imaging, including a human brain atlas. Boxes within each chapter contain clinical information, with tables of topic summaries. Presented along with clinical approaches and analyses, this is a reference for all neuroscientists, neurosurgeons, neurologists, medical students, and all students of neuroscience.

  • Waste Management for Sustainable and Restored Agricultural Soil

    • 1st Edition
    • Vijay Singh Meena + 6 more
    • English
    Waste Management for Sustainable and Restored Agricultural Soil provides a holistic approach to various mechanisms of waste management for plant nutrients, highlighting the importance of improving plant growth, nutrient concentration, and system sustainability for enhancing crop production and achieving desired environmental goals. Covering a broad overview of different kinds of wastes and waste recycling methods and sustainable management for soil health, this book focuses on both basic and applied aspects of waste management for sustainable agriculture and how nutrients are made available through waste. Academics, professionals, researchers and policymakers working in the fields of safe waste management for potential use in agricultural crop production will benefit from this book.

  • Management, Body Systems, and Case Studies in COVID-19

    • 1st Edition
    • Rajkumar Rajendram + 3 more
    • English
    Management, Body Systems, and Case Studies in COVID-19 describes the assessment and treatment of patients infected with the novel coronavirus that causes the varied symptoms of COVID-19. Detailing this multisystem disease and the organs and tissues affected, this volume features chapters on several body systems. Conditions affecting the respiratory, hematological, hepatobiliary, renal, gastrointestinal, nervous, musculoskeletal, and cardiovascular systems are addressed. The fundamental role of telemedicine during the pandemic is also discussed. This volume is relevant for all clinicians and scientists working to ensure the best outcomes for patients with COVID-19.

  • Features, Transmission, Detection, and Case Studies in COVID-19

    • 1st Edition
    • Rajkumar Rajendram + 2 more
    • English
    Features, Transmission, Detection, and Case Studies in COVID-19 examines the effects of the virus on the body, as well as its transmission and clinical profile. This volume begins with an introduction to the virus and its pathogenesis, transmission, and avoidance, followed by sections on pulmonary and cardiovascular effects, obesity, diabetes, the liver, detection issues, and biomarkers. Vaccines and treatment are also discussed. Specific case studies covered include hypoxia, acute kidney injury, pneumonia, and neurological effects. This volume is relevant for all clinicians and scientists working to ensure the best outcomes for patients with COVID-19.

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