Drugs and Enzymes
Proceedings of The Second International Pharmacological Meeting, Vol. 4
- 1st Edition - January 1, 1965
- Imprint: Pergamon
- Editors: Bernard B. Brodie, James R. Gillette
- Language: English
- eBook ISBN:9 7 8 - 1 - 4 8 3 2 - 2 3 5 1 - 3
Second International Pharmacological Meeting, Volume 4: Drugs and Enzymes is a collection of papers presented at the Second International Pharmacological Meeting on August 20-23,… Read more
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Request a sales quoteSecond International Pharmacological Meeting, Volume 4: Drugs and Enzymes is a collection of papers presented at the Second International Pharmacological Meeting on August 20-23, 1963. This volume is organized into two sections encompassing 41 chapters. The first section discusses the relationship between biochemical effects of drugs in vitro and their pharmacological effect in vivo. This section specifically examines the correlation between the action of substances on isolated smooth muscle and on the central nervous system, as well as the behavior of a centrally-acting drug and enzyme in the ion movement in the system. The second section surveys the biochemical mechanisms of drug toxicity. Considerable chapters in this section are devoted to the effect of drug toxicity, such as altered drug metabolism, enzyme induction, morphological changes, hepatic effects, and photosensitivity. This book will prove useful to pharmacologists, neurologists, biochemists, and researchers who are interested the fields of drugs and drug toxicity.
List of Authors
Introduction
Relationship Between Biochemical Effects of Drugs In Vitro and their Pharmacological Effect In Vivo
Reversible Binding as a Complication in Relating the In Vitro Effect of Drugs to their In Vivo Activity
Correlations between the Action of Substances on Isolated Smooth Muscle and on the Central Nervous System
Drugs and Enzymes of Ion Movement in the Central Nervous System
Metabolism, Activity and Some Effects of Drugs in Mammalian Non-myelinated Nerve Fibers — Discussion to paper by H. Mcllwain
Neurophysiological and Biochemical Correlations in Isolated Nerve Cell Preparations at Rest and during Impulse Activity
Effect of Digitalis on Membrane Adenosine Triphosphatase of Cardiac Muscle
Discussion to paper by K. Repke
In Vivo Factors Influencing the Efficacy of Chelating Compounds as Therapeutic Agents for Metal Toxicity
Effets metaboliques de quelques radio-protecteurs
A Contribution to the Effects of Protective Drugs — Discussion to paper by Ζ. M. Bacq and C. Liιbecq
Carbonic Anhydrase Inhibitors
The Kinetics of Carbonic Anhydrase and its Inhibition In Vivo
Comparison by Direct Measurement of Sulfonamide Carbonic Anhydrase Inhibition in Whole Cells and in Enzyme Solutions — Discussion to paper by T. H. Maren
Monoamine Oxidase Inhibitors
Discussion to paper by S. Spector
Enzymes as Therapeutic Agents
Modifiers of Adrenocortical Function
Modifiers of Adrenocortical Function — Some Clinical Aspects — Discussion to paper by R. Neher and F. W. Kahnt
Xenon Bonding to Proteins — Relationship to Anesthetic Action
Discussion to paper by R. M. Featherstone
Biochemical Mechanisms of Drug Toxicity
Individual Variation in Drug Metabolism as Cause of Drug Toxicity
Discussion to paper by W. Kalow
Impairment of Drug Metabolism in Drug Toxicity
Enzyme Induction and Drug Toxicity
Morphological Changes in the Endoplasmic Reticulum of the Liver Cells with Enzyme Induction after Pretreatment with Several Drugs—Discussion to paper A. H . Conney
Biochemical Factors.in the Formation of Active and Toxic Metabolic Products
Discussion to paper by J. Axelrod
Biochemistry of Rodenticides
Mechanisms of Drug-induced Carcinogenesis
Biochemical Factors in Carbon Tetrachloride Toxicity
Investigations on the Early Effects of CC14 on Lipid Transport — Discussion to paper by M. G. Horning et al.
Hepatic Lipid Transport and Lipoprotein-protein Synthesis: Effects of CC14 Intoxication — Discussion to paper by M. G. Horning et al
Cumulative Effects of Reserpine on the Pituitary-adrenocortical and Sympathetic Nervous System
Inactivation of SH-Enzymes in Drug-induced Hemolysis
Discussion to paper by S. Rapoport and D. Scheuch
Hepatotoxic Drugs Causing Porphyria in Man and Animals
Photosensitivity to Drugs
Specificity in Delayed-type Reactions to Simple Chemicals
Metabolische Studien mit Thalidomid und seinen Stoffwechselprodukten
Discussion to paper by J. W . Faigle et al.
Chloroquine Toxicity
Index
- Edition: 1
- Published: January 1, 1965
- No. of pages (eBook): 516
- Imprint: Pergamon
- Language: English
- eBook ISBN: 9781483223513
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