Clostridium Difficile
Its Role in Intestinal Disease
- 1st Edition - October 22, 2013
- Editor: Rial D. Rolfe
- Language: English
- eBook ISBN:9 7 8 - 1 - 4 8 3 2 - 8 9 0 5 - 2
Despite the tremendous progress made during the last few years in understanding the pathogenesis, epidemiology, diagnosis, and treatment of Clostridium difficile-associated… Read more
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Request a sales quoteDespite the tremendous progress made during the last few years in understanding the pathogenesis, epidemiology, diagnosis, and treatment of Clostridium difficile-associated intestinal disease, many extremely important and fundamental questions remain to be answered. The objectives of this book are to summarize the available information regarding Clostridium difficile and its role in intestinal disease and to serve as a basis for future investigations in this challenging area.Clostridium difficile: its role in Intestinal Disease. An excellent volume that should appeal not only to the devotee of C difficile but to all gastroenterologists and microbiologists, this will not languish on my library shelves like so many other books I have reviewed. It will be regularly thumbed. --R.H. George, consultant microbiologist, Children's Hospital, BirminghamClostridium difficile: Its Role in Intestinal disease. The book is well written and informative; it has a vast amount of information packed in it...this book would be a welcome addition to the researchers and clinicians interested in C difficile-associated intestinal diseases. --Edward Balish, University of Wisconsin Medical School
Chemical, materials science, mining, and metallurgical engineers.
Introduction. Historical Aspects. Clinical Aspects of Clostridium difficile-Associated Intestinal Disease. Antimicrobial Agent-Associated Diarrhea in Adult Humans. Clostridium difficile in Infants and Children. Other Clostridial Causes of Diarrhea and Colitis in Man and Animals. Immunological Response to Clostridium difficile Infection. Animal Models of Clostridium difficile-Associated Intestinal Disease. Role of the Hamster Model of Antibiotic-Associated Colitis in Defining the Etiology of the Disease. Other Animal Models of Intestinal Disease Caused by Clostridia. Pathogenic Mechanisms of Clostridium difficile-Associated Intestinal Disease. Purification and Properties of Toxins A and B of Clostridium difficile. Mechanism of Action of Clostridium difficile Toxins. Microbial Ecology of Clostridium difficile. Asymptomatic Intestinal Colonization by Clostridium difficile. Epidemiology of Clostridium difficile-Associated Intestinal Disease. General Epidemiology, Potential Reservoirs, and Typing Procedures. Diagnosis of Clostridium difficile-Associated Intestinal Disease. Pathology and Diagnosis of Clostridium difficile Disease. Isolation and Identification of Clostridium difficile: Tissue Culture Cytotoxicity Assay. Other Potential Diagnostic Techniques. Therapy of Clostridium difficile-Associated Intestinal Disease. Therapy Directed against Clostridium difficile and Its Toxins: Complications of Therapy. Surgical Aspects of Therapy. Prevention of Clostridium difficile-Associated Intestinal Disease. Conclusions. Conclusions and Unanswered Questions. Each chapter includes references. Index.
- No. of pages: 408
- Language: English
- Edition: 1
- Published: October 22, 2013
- Imprint: Academic Press
- eBook ISBN: 9781483289052
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