Trophic Regulation of the Basal Ganglia

1. Fibroblast Growth Factor-2, Ganglioside GM1 and the Trophic Regulation of the Basal Ganglia. Focus on the Nigrostriatal Dopamine Neurons


2. DARPP-32/Protein Phosphatase-1/Na+/K+ATPase System: A Mechanism for Bidirectional Control of Cell Function


3. Muscle-Derived Differentiation Factor and its Regulation of the Tyrosine Hydroxylase Gene in the Developing, Adult and Lesioned Rat Brain


4. Glucocorticoid and Estrogen Effects on the Nigrostriatal and Mesolimbic Dopaminergic Systems


5. Factors Associated to Dopaminergic Cell Death in Parkinson's Disease


6. Compensatory Mechanisms at Dopamine D-2 Receptors


7. Oxidative Stress and Reduced Receptor Responsiveness in Senescence


8. Expression, Regulation and Receptor Distribution of Neurotrophins in the Mammalian Central Nervous System


9. Localization of Neurotrophins and Their Receptors at the mRNA and Protein Level


10. Effects of Brain-Derived Neurotrophic Factor on Injured Dopaminergic Neurons


11. Fibroblast Growth Factors and Parkinson's Disease


12. Homeobox Peptides as a Novel Class of Neurotrophic Molecules


13. Growth Factors Involved in the Development, Maturation and Neuroplasticity of Midbrain Dopamine Neurons


14. Ganglioside and Growth Factor Interactions Promote Mesencephalic Cell Survival from the Excitotoxic Actions of 2,4,5-Trihydroxyphenylalanine


15. Trophic Factors and GM1 Ganglioside in the Basal Ganglia


16. The Role of Gangliosides and Trophic Factors in Brain Repair


17. Features of the Trophic Action of Polyamines


18. Acidic and Basic Fibroblast Growth Factors are Present in, and Produce Effects upon, Mesencephalic Dopamine Neurons


19. Presence of Interleukin-1 in the Central Nervous System


20. Cellular Immediate-Early Genes in the Nervous System: Genes for All Reasons?


21. Neuropeptide Synthesis in Astrocytes: Possible Trophic Roles


22. Beta-Amyloid Precursor: A Neuronal and Glial-Derived Protein with Trophic-like Activities


23. Neuron-Glia Interactions: Receptor Induced Events in Single Astroglial Cells and their Implications for Neuronal Excitability and for Neurotransmission


24. Astrocytic Kynurenines as Modulators of Dopaminergic Function in the Rat Basal Ganglia


25. Neurochemical and Behavioral Studies on L-dopa Toxicity in the Model of Manganese Lesioned Nigrostriatal Pathway in the Rat: Evidence for a Protective Effect of the GM1 Lactone Siagoside


26. The MPTP Model of Parkinson's Disease in the Mouse. Modafinil - A New Potential Neuroprotective Agent


27. Recovery from MPTP-Induced Parkinsonism in Monkeys and Cats: Similar Mechanisms?


28. The Evaluation of Antiparkinsonian Activities in Primate Models of Parkinsonism


29. The 3-Acetylpyridine Model of Parkinsonism: Use of Cytochrome Oxidase Gene Expression as an Index of Alterations in Basal Ganglia Function


30. Neuronal Plasticity: A Potential Role in Spiny Striatal Neuron Degeneration in Huntington's Disease


31. Plasticity Responses After Neonatal Dopamine Lesions Induced with 6-Hydroxydopamine


32. Compensatory Neurobiological Changes after Partial Lesions with 6-Hydroxydopamine


33. Responses of Neostriatal Dopaminoceptive Cells to the Ischemic Insult


34. Morphological and Functional Adaptation of Basal Ganglia Neurons after Cerebral Ischemia


35. Clearance and Diffusion of Locally Applied Dopamine in Normal and 6-Hydroxydopamine-Lesioned Rat Striatum


36. Target-Specific Outgrowth from Grafted Dopaminergic Neurons


37. The Pharmacotherapy of Parkinson's Disease: Current Status and Future Opportunities


38. Signal Transduction Mechanisms on Striatal Dopaminergic Neurons: Importance in Neurotrophism and Neuropathology

Author Index

Subject Index