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Books in Neuroscience

Elsevier's Neuroscience collection empowers educators, researchers, and students with actionable knowledge to drive collaborative research and advancements in the field. Content covers the nervous system's intricate workings, covering branches like Affective, Behavioral, and Cognitive neuroscience to investigate the neural basis of emotions, behavior, and cognitive functions. Spanning from Molecular and Cellular Neuroscience to Developmental Neuroscience, content provides insights into brain function in health and disease.

    • Phenotyping of Human iPSC-derived Neurons

      • 1st Edition
      • September 9, 2022
      • Elizabeth D. Buttermore
      • English
      • Paperback
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      • eBook
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      Phenotyping of Human iPSC-derived Neurons: Patient-Driven Research examines the steps in a preclinical pipeline that utilizes iPSC-derived neuronal technology to better understand neurological disorders and identify novel therapeutics, also providing considerations and best practices. By presenting example projects that identify phenotypes and mechanisms relevant to autism spectrum disorder and epilepsy, this book allows readers to understand what considerations are important to assess at the start of project design. Sections address reproducibility issues and advances in technology at each stage of the pipeline and provide suggestions for improvement. From patient sample collection and proper controls to neuronal differentiation, phenotyping, screening, and considerations for moving to the clinic, these detailed descriptions of each stage of the pipeline will help everyone, regardless of stage in the pipeline. In recent years, drug discovery in the neurosciences has struggled to identify novel therapeutics for patients with varying indications, including epilepsy, chronic pain, and psychosis. Current treatment options for such patients are decades old and offer little relief with many side effects. One explanation for this lull in novel therapeutics is a lack of novel target identification for neurological disorders (and target identification requires exemplar preclinical data). To improve on the preclinical work that often relies on rodent modeling, the field has begun utilizing patient-derived induced pluripotent stem cells (iPSCs) to differentiate neurons in vitro for preclinical characterization of neurological disease and target identification.
    • Essential Tremor: Current Concepts and Controversies

      • 1st Edition
      • Volume 163
      • May 26, 2022
      • Sheng-Han Kuo + 1 more
      • English
      • Hardback
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      • eBook
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      Tremors, Volume 163 in the International Review in Neurobiology serial highlights new advances in the field, with this new volume presenting interesting chapters. Each chapter is written by an international board of authors.
    • Neuroimaging Anatomy, Part 1: Brain and Skull, An Issue of Neuroimaging Clinics of North America

      • 1st Edition
      • Volume 32-3
      • July 19, 2022
      • Tarik F. Massoud
      • English
      • Hardback
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      • eBook
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      In this issue of Neuroimaging Clinics, guest editor Dr. Tarik F. Massoud brings his considerable expertise to the topic of Neuroimaging Anatomy, Part 1: Brain and Skull. Anatomical knowledge is critical to reducing both overdiagnosis and misdiagnosis in neuroimaging. This issue is part one of a two-part series on neuroimaging anatomy that focuses on the brain, with each article addressing a specific area. The issue also includes an article on Brain Connectomics: the study of the brain’s structural and functional connections between cells.
    • Posttraumatic Epilepsy

      • 1st Edition
      • October 21, 2022
      • Carrie R. Jonak + 2 more
      • English
      Posttraumatic Epilepsy: Basic and Clinical Aspects provides a synthesized resource on the recent basic and clinical science developments in the field of posttraumatic epilepsy. This book provides a clear understanding of the history of studies and epidemiology of posttraumatic epilepsy after head injury. The book also considers the neuropathology of posttraumatic epilepsy and clinical trials of antiepileptogenic agents evaluated after traumatic brain injury. The book covers the basic science of animal models of traumatic brain injury and the necessary and sufficient changes that must occur to generate epilepsy after head trauma. The authors explore potential mechanisms and novel therapeutic approaches to prevent posttraumatic epilepsy. The book is written for basic and clinical researchers in neuroscience as well as for clinicians treating patients with epilepsy.
    • Tinnitus and Hyperacusis

      • 1st Edition
      • March 12, 2022
      • Jos J. Eggermont
      • English
      • Paperback
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      Tinnitus and Hyperacusis: Facts, Theories, and Clinical Implications provides an overview on this burgeoning field, covering the underlying mechanisms and potential treatments for these disorders. The book begins with an overview of the etiology and genetics behind tinnitus and hyperacusis. The author then proposes two parallel neural pathways underlying these conditions and provides a basis for connecting animal to human research. Neurotransmitters, neuromodulators and immediate early genes are discussed, along with a detailed comparison of about a dozen models aimed at explaining tinnitus and hyperacusis, including the neurophysiological model, the neural synchrony model and the cortical map reorganization and filling-in model. Potential treatments of tinnitus and hyperacusis, from behavioral to non-invasive neuromodulation are also discussed. This book is written for clinical neuroscientists, audiologists, neuro-otologists, neurologists and clinical psychologists.
    • Defence from Invertebrates to Mammals: Focus on Tonic Immobility

      • 1st Edition
      • Volume 271
      • March 29, 2022
      • English
      • Hardback
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      • eBook
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      Defence from Invertebrates to Mammals: Focus on Tonic Immobility, Volume 273 in the Progress in Brain Research series, highlights new advances in the field. Chapters in this new release include Defensive responses in invertebrates, Introduction to defensive behavior in vertebrates, Neural circuits of fear and defensive behavior, Fear-associated factors modulating TI, Environmental, ecological and methodological factors of TI Modulation, The neuroethological approach to defense in rabbits, Neurophysiological mechanisms of TI, Neuromediators, brain areas and circuits involved in defense responses, Autonomic correlates of defense responses, Neuroendocrine correlates of stress and TI, Pain control during TI and other immobility models, and more.
    • Neuropalliative Care

      • 1st Edition
      • Volume 190
      • August 31, 2022
      • English
      • Hardback
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      Neuropalliative Care, Part One, Volume 190 covers a type of care that is given when there is no cure for the neurological disorder and the patient is in distress. It provides a scholarly background of neuropalliative care, from historic underpinnings to its practice in various geographical regions, along with best practices for specific neurological disorders. It covers the work of multi or interdisciplinary teams whose care is intended to make the patient as comfortable as possible and includes partners and families in treatment plans.
    • Respiratory Neurobiology

      • 1st Edition
      • Volume 189
      • August 26, 2022
      • English
      • Hardback
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      • eBook
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      Respiratory Neurobiology: Physiology and Clinical Disorders, Part Two, Volume 189 is one of two volumes on the neurology of breathing. This volume focuses on pathologies attributable to abnormalities of the neural control of breathing, breathing problems that may occur in neurological diseases, and the neurological complications of respiratory diseases, while volume one focuses on the neurophysiology of breathing.
    • Neurocircuitry of Addiction

      • 1st Edition
      • November 29, 2022
      • Nicholas W. Gilpin
      • English
      • Paperback
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      People use drugs for many different reasons, including the pursuit of "high," social factors and self-medication of other conditions. Many millions of people are addicted to at least one substance, and the cost of addiction is immense, at both the individual and societal levels. Neurocircuitry of Addiction is the first book of its kind, with a focus on addiction neuroscience from a neural circuit perspective. This book begins with a primer on circuit-based neuroscience that equips the reader with an understanding of the applications described throughout the book. Each subsequent chapter positions a different brain region at the "center" of addiction neurocircuitry and goes on to describe the anatomical connectivity of that brain region, how those circuits are affected by drug exposure, and the role of those circuits in controlling addiction-related behaviors. All chapters of this book are written by content experts for a target audience that has some basic neuroscience background, but no prior in-depth knowledge regarding the neurocircuitry of addiction.
    • Neurodivergence and Architecture

      • 1st Edition
      • Volume 5
      • September 29, 2022
      • English
      • Hardback
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      • eBook
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      Neurodivergence and Architecture, Volume Five, the latest release in the Developments in Neuroethics and Bioethics series, focuses on the new and fascinating ethical and legal challenges posed by neurotechnology and its global regulation. Topics in this new release cover STS on architecture, Embodied Rhetoric/ Disability Studies, Autoethnography, Bioethics/Materialis... Feminism, Advocacy, Cultural Commentary: Being Autistic Together, An autistic perspective on built spaces, Empty spaces and refrigerator boxes: making autistic spaces, On the Losing Myself Project, Neither Use nor Ornament (NUNO) project, Madness and (Be)coming Out Within and Through Spaces of Confinement, and more.