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Elsevier

Books in Life sciences

Elsevier's Life Sciences collection helps researchers get comprehensive coverage and up-to-date information on the study of living organisms, their processes, and interrelationships, spanning disciplines like biology, genetics, and biochemistry, and addressing emerging trends such as genomics, biotechnology, and sustainability, essential for advancing knowledge and driving innovation in the field.

  • Osmolytes and Intrinsically Disordered Proteins: From Functional Regulation to Disease Pathogenesis

    • 1st Edition
    • Volume 211
    • English
    Osmolytes and Intrinsically Disordered Proteins: From Functional Regulation to Disease Pathogenesis, Volume 112 delves into the fascinating interplay between osmolytes and intrinsically disordered proteins (IDPs), exploring their pivotal roles in cellular function and disease mechanisms. This volume brings together experts to present cutting-edge research on how osmolytes regulate functional behavior of IDPs and ensure cellular stability and adaptability under stress conditions. Specific chapters cover Functional diversity of IDPs and their structural heterogeneity: Protein structure-function continuum, Osmolytes as structure-function regulators of intrinsically disordered casein, Synergism of the effects of osmolytes and crowders on structure and function of IDPs/IDRs: The natural habitat, and more.Additional chapters delve into Osmolyte-IDP Interactions during Desiccation, Modulation of aggregation/fibrilla... propensity of IDPs by osmolytes, Osmolytes in modulating the structural and functional integrity of α-synuclein: a study based on Parkinson's disease, Regulation of the structural dynamics, aggregation, and pathogenicity of polyQ-expanded Huntingtin by osmolytes, Aggregation and inhibitory strategies of amyloid fibrillation, and much more.

  • Colorectal Imaging

    From Basic to Advanced Concepts
    • 1st Edition
    • Luca Saba
    • English
    Colorectal Imaging: From Basic to Advanced Concepts provides an exhaustive overview of today’s basic and advanced principles of colorectal imaging, focusing not only on oncologic but also inflammatory, infective, and ischemic pathologies and complications. The book reviews basic colorectal cancer information, examines imaging techniques and analysis, and concludes with a review of non-neoplastic pathologies. It is a useful resource for scientists, physicians, and medical students in the discipline of radiology, highlighting the critical role of contemporary imaging in guiding clinical and surgical approaches and providing the knowledge needed to confidently choose the most appropriate imaging examination.

  • Organic Mechanochemistry

    A New Tool for Sustainable Synthesis
    • 1st Edition
    • Davor Margetic
    • English
    Organic Mechanochemistry: A New Tool for Sustainable Synthesis presents the greener chemical method to a broader reading audience, including chemical practitioners. Descriptions of each method, followed by examples on sustainability aspects and applications give readers a better understanding and realization of its possibilities. Mechanochemistry, a nonconventional method for inducing the chemical reaction by application of mechanical energy in solid state, has been recognized as beneficial as mechanochemically conducted reactions hold diverse environmental sustainability advantages in manufacturing processes.

  • Update on Obesity, An Issue of Endocrinology and Metabolism Clinics of North America

    • 1st Edition
    • Volume 54-1
    • Caroline M. Apovian + 1 more
    • English
    In this issue of Endocrinology and Metabolism Clinics, guest editors Drs. Caroline M. Apovian and Dong Wook Kim bring their considerable expertise to the topic of Update on Obesity. Top experts in the field cover the latest research regarding weight loss drugs, drug safety, pharmacotherapy, AI, and nutritional/lifestyl... changes for managing obesity.

  • The Immunological Synapse Part C

    • 1st Edition
    • Volume 193
    • English
    The Immunological Synapse - Part C, Volume 193 in the Methods in Cell Biology series provides state-of-the-art and detailed methods for the study of the T cell, natural killer (NK) cell and B cell immunological synapses. Topics covered in this third volume include tau-STED microscopy for 3D-quantitative colocalization of lytic granule markers, image processing approaches for 3D-analysis of markers and for microtubule remodeling quantification at the immunological synapse, flow cytometry to analyze NK cell-target cell conjugation, imaging flow cytometry to quantify a range of different subcellular processes at the immunological synapse, imaging techniques aimed at quantitatively analyzing B cell immunological synapse formation, quantification of force-mediated antigen extraction in the B cell immune synapse using DNA-based tension sensors, measuring interaction forces between T lymphocytes and their target cells using live microscopy and laminar shear flow chambers, measuring interaction kinetics between T cells and their target tumor cells with optical tweezers, and gauging antigen recognition by human primary T-cells featuring orthotopically exchanged TCRs of choice. Additionally, this volume includes methods to isolate and characterize primary NK cells and enrich the KIR2DL1+ population, and to expand γδ T cells and evaluate their cytotoxicity.

  • Handbook of Immunoassay Technologies

    Approaches, Performances, and Applications
    • 2nd Edition
    • Sandeep K. Vashist + 1 more
    • English
    Handbook of Immunoassay Technologies: Approaches, Performances, and Applications, Second Edition unravels the role of immunoassays in the biochemical sciences. During the last four decades, a wide range of immunoassays has been developed, ranging from the conventional enzyme-linked immunosorbent assays to the smartphone-based point-of-care formats. The book discusses how advances in rapid biochemical procedures, novel biosensing schemes, fully integrated lab-on-a-chip platforms, prolonged biomolecular storage strategies, device miniaturization and interfacing, and emerging smart system technologies that have paved the way for next-generation immunoassays.Revised and updated, the second edition of Handbook of Immunoassay Technologies: Approaches, Performances, and Applications covers all the relevant, timely, and important developments in the field. This edition offers new content on topics such as antibody production for immunodiagnostics, multiplex immunoassays, chemiluminescent immunoassays, immunoassays for newborn screening, and immunoassays of viruses like SARS-CoV-2, HIV, Ebola, and Hepatitis C. The addition of these new topics as well as up-to-date content make the second edition a valuable and comprehensive resource on immunoassays.

  • Building a Space-Faring Civilization

    Advancing the Renaissance of Science, Medicine and Human Performance in Civilian Spaceflight
    • 1st Edition
    • Michael Schmidt A + 1 more
    • English
    Building a Space-Faring Civilization: Advancing the Renaissance of Science, Medicine, and Human Performance in Civilian Spaceflight explores an expanding, unique new trajectory for humankind—the settlement of space by civilians. For the first time in history, average humans can contemplate journeys to Earth orbit, the Moon, and Mars with the idea of space settlement as a plausible reality. As the numbers of spacefaring civilians grow, medical personnel will be asked to meet their complex needs through an ever-expanding discipline—space medicine. But this will require a rapidly advancing science to address what some are calling the next great age in space.This book gathers some of the most accomplished thought leaders in the field of human spaceflight today. Collectively, they helped build the international space station (ISS), develop the field of orbital medicine, guide the development of commercial orbital platforms, plan missions to the Moon and Mars, and forge the innovation necessary for the commercial spaceflight industry to thrive today. The result is an exceptional source of wisdom, experience, and insight surrounding the current biomedical, technical, industrial, legal, and social implications of what is emerging as a true renaissance period in human history.

  • Retinoids in Development and Disease

    • 1st Edition
    • Volume 161
    • English
    Retinoids in Development and Disease, Volume 161 in the Current Topics in Developmental Biology series focuses on the role of retinoids during development and disease. Topics covered include Retinoids, Retinol-Binding Protein 2 (RBP2), Retinol-Binding Protein 4 (RBP4): Obesity and Metabolic Disease, Early Retinoic Acid Signaling Organizes the Body Axis and Defines Domains for the Forelimb and Eye, Rethinking Retinoic Acid Self-Regulation: A Signaling Robustness Network Approach, Meiotic initiation in the fetal ovary without retinoic acid receptors: an unforeseen twist, Action of retinoic acid on progenitor cells in the testis, amongst many other topics.Additional sections cover Retinoic acid homeostasis and disease, Redefining the roles of endogenously produced retinoic acid in heart development and regeneration: lessons from genetic models, The Multifaceted Roles of Retinoids in Vision, Eye Development, and Retinal Degenerative Diseases, Essential roles for retinoid signaling in craniofacial development, and much more.

  • ADARs

    • 1st Edition
    • Volume 710
    • English
    ADARs, Volume 710 in this ongoing series, highlights new advances in the field, with this new volume presenting interesting chapters written by an international board of authors. Updates in this new release include Yeast as a discovery tool for hyperactive ADARs, X-ray crystallography of ADAR-RNA complexes, Enrichment capture enhances the ability to detect A-to-I editing, Editing specificity of ADAR isoforms, Novel chemical tools for detection methods of A to I sites, En Masse Evaluation of RNA Guides (EMERGe) for ADARs, Mouse models for defining physiological functions of ADARs, Nanopore sequencing to detect A-to-I editing sites, CellREADR: An ADAR-based RNA sensor, and more.Additional sections cover Site-directed RNA editing with MS2-ADAR systems, Sequencing and Bioinformatic Tools for Accurate Assessment of A to I editing in Complete Transcriptomes, Aptazyme-directed A to I RNA editing, and Obstacles in quantifying A-to-I editing by Sanger Sequencing.

  • Materials and Components of Biosensors in Healthcare

    Volume 2
    • 1st Edition
    • Md Saquib Hasnain + 2 more
    • English
    Materials and Components of Biosensors in Healthcare: Volume Two provides comprehensive coverage and a detailed examination of the various materials and components used in the development of biosensors. The book begins with an introduction and then discusses the biochemical, inorganic, and biopolymeric components used in biosensor assembly. It goes on to detail a range of materials such as nanoparticles, biological cellular structures, electrochemical, and electromagnetic materials and how they are used in biosensors.Combined with Fundamentals of Biosensors in Healthcare, Volume One, and Applications of Biosensors in Healthcare, Volume Three, this trio provides holistic reference sources suitable for researchers, graduate students, postgraduates, and industry professionals involved in biosensing, biosensors, and biomedical applications.

  • Epigenetic Regulation of Cancer - Part D

    • 1st Edition
    • Volume 390
    • English
    Epigenetic Regulation of Cancer, Part D, Volume 390 in the International Review of Cell and Molecular Biology series, highlights new advances in the field, with this new volume presenting interesting chapters on a variety of hot topics, including Revisiting Epigenetic Regulation in Cancer: Evolving Trends and Translational Implications, Epigenetic Alteration in Cervical Cancer Induced by Human Papillomavirus, Integrative analysis of transcriptome, chromatin accessibility, cell surface antigen in single cell level for AML, Role of miRNAs as epigenetic regulators of immune checkpoints in lung cancer immunity, and much more.Other chapters cover The translational potential of epigenetic modulatory bioactive phytochemicals as adjuvant therapy against cancer, Strategies for improving chemotherapeutic sensitivity and the epigenetic regulation of doxorubicin resistance, and more.

  • Revolutionizing Medical Systems using Artificial Intelligence

    A Breakthrough in Healthcare
    • 1st Edition
    • Ashish Kumar + 1 more
    • English
    Revolutionizing Medical Systems using Artificial Intelligence: A Breakthrough in Healthcare provides an overview of various machine learning and deep learning techniques, addressing the needs of patients and the necessity for medical aid at early stages of disease. The book reviews, analyzes, and compares the different methodologies utilized for the prediction and detection of diseases. In addition, it explores the possible deployment of these advancements in medical systems, from paper to practice. With the advent of technology, tele consultation, telemedicine, and mobile health care, it is now possible to provide continuous monitoring of the health of patients.This title fulfills the needs of connected healthcare systems, providing insights into the role of Artificial Intelligence in the prognosis, diagnosis, and analysis of several diseases. It will be a valuable resource for health professionals, scientists and researchers, health practitioners, students, and all those who wish to broaden their knowledge in the challenging field of artificial intelligence in medical systems and diseases.

  • Hypothalamus

    • 1st Edition
    • Volume 127
    • English
    Vitamins and Hormones series, highlights new advances in the field, with this new volume presenting interesting chapters. Each chapter is written by an international board of authors.

  • Animal Models of Disease Part C

    • 1st Edition
    • Volume 192
    • English
    Animal Models of Disease, Part C, Volume 192 in the Methods in Cell Biology series, highlights advances in the field, with this new volume presenting interesting chapters on a variety of timely topics, including Characterizing tumor-infiltrating group 1 innate lymphoid cells in PyMT breast tumors, The current models unravel the molecular mechanisms underlying the intricate pathophysiology of Alzheimer’s disease using Zebrafish, Colitis mouse model, Matching model with mechanism: appropriate animal models for studying various aspects of diabetes pathophysiology, Human cancer cells xenografts to assess the efficacy of granulysin-based therapeutics, and much more.Additional sections cover Antimicrobial regime for gut microbiota depletion in experimental mice models, Evaluating polyglutamine protein aggregation and toxicity in transgenic Caenorhabditis elegans models of Huntington's disease, A model of intraperitoneal ovarian cancer to study tumor responses to radioimmunotherapy, Metallic nanoparticles biodistribution for the study of lymphoma in animal models, Stereotactic injection of murine brain tumor cells for neuro-oncology studies, Evaluating amyloid-beta aggregation and toxicity in transgenic Caenorhabditis elegans models of Alzheimer's disease, and much more.

  • Artificial Intelligence in Microbiology: Scope and Challenges volume-II

    • 1st Edition
    • Volume 56
    • English
    Artificial Intelligence in Microbiology: Scope and Challenges, Volume-II, Volume 56 covers changes due to the emergence of Artificial Intelligence (AI). AI is being used to analyze massive data in a predictable form, about the behavior of microorganisms, to solve microbial classification-relat... problems, and more. Chapters include Taking on the resistance: AI and battle against antimicrobial resistance, AI-powered insights into microbial communities for bioremediation strategies, Efficient and cost-effective production of viral vaccines via AI, Production and development of novel drug targets through AI, Use of AI in neuroscience, Role of Artificial Intelligence in studying metagenomics of Microbes: Decoding the microbial Sphere, and more.Other chapters explore Exploring the functional role of bacterial proteins via AI, Application of AI in Aquaculture/Fisherie... Disease identification, detection, diagnosis, drug development, Artificial Intelligence in drug discovery & development; scope and challenges, Production of bacteriocins by AI: as food preservative, Exploring the Role of Artificial Intelligence in the Microbial remediation of heavy metals, Uses of Artificial Intelligence in the Agricultural Pest Management, Microbial fermentation processes using Artificial Intelligence, and more.

  • Artificial Intelligence in e-Health Framework, Volume 1

    AI, Classification, Wearable Devices, and Computer-Aided Diagnosis
    • 1st Edition
    • Sudip Paul + 1 more
    • English
    Artificial Intelligence in e-health Framework, Volume One: AI, Classification, Wearable Devices, and Computer-Aided Diagnosis presents a variety of AI techniques and applications for solving issues in the healthcare industry. As Artificial Intelligence is increasingly incorporated into medical systems and methods, it is critical to understand the formulations and basics of machine and deep learning as well as how to implement these advances into practice. This book specifically explores Artificial Intelligence developments in disease diagnosis, health monitoring, medical image recognition, and diagnostics, as well as e-health records management.This is a valuable resource for health professionals, scientists, researchers, students, and all who wish to broaden their knowledge in this advancing technology.

  • Nuclear Proteins

    • 1st Edition
    • Volume 143
    • English
    Advances in Protein Chemistry and Structural Biology, Volume 143 in the series, covers reviews of methodology and research in all aspects of protein chemistry, including purification/express... proteomics, modeling and structural determination and design. Chapters in this new release include Therapeutic insight into the role of nuclear protein HNF4α in liver carcinogenesis, Structural mechanism of nucleoporins in cancer disease, Identification of nuclear matrix proteins (novel genes) in bladder cancer using Bioinformatic approaches, A comparative study of nuclear proteins of different cancers - A systematic review, Role of lamins in cellular physiology and cancer, and much more.Other chapters cover Nuclear Hormone Receptors as Drug Targets: Advancements and Future Prospects, Proteins binding to tandemly repeated DNA: familiar strangers, HMGB1, R-loops and genome stability, Nuclear tau accumulation in Alzheimer's Disease, and Histone deacetylase's (HDACs) regulates Tau function in Alzheimer's Disease.

  • Applications of Biosensors in Healthcare

    Volume 3
    • 1st Edition
    • Md Saquib Hasnain + 2 more
    • English
    Applications of Biosensors in Healthcare: Volume 3 details and explores the various ways biosensors are used in healthcare, disease management, and therapeutic delivery.This is the third volume out of three volumes covering biosensors in healthcare. The volume discusses various types of biosensors and their use in diagnostics, health monitoring, disease detection, and therapeutic delivery. Combined with the Volume 1, Fundamentals of Biosensors in Healthcare, and Volume 2, Applications of Biosensors in Healthcare, the volumes provide a holistic reference source suitable for researchers, graduate students, postgraduates, and industry professionals involved in biosensing, biosensors, and biomedical applications.

  • Profiles of Drug Substances, Excipients, and Related Methodology

    • 1st Edition
    • Volume 50
    • English
    Profiles of Drug Substances, Excipients, and Related Methodology, Volume 50 includes comprehensive profiles of four drug compounds: Sofosbuvir, Nateglinide, Linagliptin, and Dronedarone, providing comprehensive knowledge on their physical and chemical properties, synthesis and degradation pathways, analytical techniques for identification and quantification, separation methods, and pharmacology of drug substances. Finally, this volume includes a review article related to the Applications of Cyclodextrins in Pharmaceutical and Related Fields, along with a chapter on Fenamates Degradation. This information is highly valuable to professionals in the field, but having it all in one place is a great benefit to readers.The Profiles series encompasses five review articles and database compilations on various topics, including the physical profiles, analytical profiles, ADME profiles, methodologies related to the characterization, and methods of chemical synthesis of drug substances and excipients.

  • Coffee

    • 1st Edition
    • Volume 114
    • English
    Coffee, Volume 112 gives the latest updates on one of the premier global traded commodities. With its annual income of approx. USD 200 billion, it supports the livelihoods of nearly 25 million smallholder farmers. In this updated edition, chapters cover The history and genetic diversity of arabica coffee, The importance of wild coffee species in a scenario of climate changes, Coffee plant architecture, Water and heat constraints to coffee ecophysiology and production, The impacts of irradiance on coffee growth and ecophysiology in a context of climate changes, Omic technologies contribution to unveil coffee resilience responses to climate changes, and much more.Additional chapters delve into Agroforestry as an alternative management system to improve coffee crop sustainability and bean quality, Could breeding of new arabica coffee varieties be a response to the climate change?, Selection, development, and management of robusta coffee genotypes under a climate change perspective, Grafting coffee for productivity and health during a changing climate, Coffee somatic embryogenesis: advances, limitations, and perspectives for mass propagation, and many other topics.

  • Microbiota-Gut-Brain Axis and CNS Disorders

    Recent Progress and Perspectives
    • 1st Edition
    • Neeraj Mishra + 1 more
    • English
    Microbiota-Gut-Brain Axis and CNS Disorders: Recent Progress and Perspectives on Human Disease summarizes the main findings on gut-brain axis in different types of CNS disorders, providing a complete overview of the field. The content helps unravel the complex interactions of the microbiota-gut-brain... in CNS disorders to pave a better understanding of microbiota-mediated pathogenesis, avenues for noninvasive prognosis, and therapeutic possibilities leveraging microbiota-gut-brain... modulations. Coverage includes the role of the microbiota-gut-brain axis and gut virome on human diseases including Alzheimer’s Disease, Parkinson’s Disease, Huntington’s Disease, Depression and Anxiety, Autism Spectrum Disorder, Multiple Sclerosis, Stroke, and others.This book will satisfy the urgent need for a broader view of the current associations between gut microbiota alterations and development of CNS disorders, including the use of novel therapeutic approaches for restoring the correct intestinal bacteria content. It is the perfect reference for translational and clinical gut and microbiome researchers tackling the challenges of delivering genes and drugs in a more targeted and efficient manner for the treatment of CNS disorders.

  • Translational Cardiology

    • 1st Edition
    • Jeffrey A. Bakal + 2 more
    • English
    Translational Cardiology provides a cardiology-specific instructional guide to translational medical research that will serve as a practical, step-by-step roadmap for taking a biomedical device, potential therapeutic agent, or research question from idea through demonstrated clinical benefit. Fundamentally, the volume aims to help bridge the gap between current research and practice. Written by a team of expert medical, biomedical engineering, and clinical research experts in cardiology, this book provides a clear process for understanding, designing, executing, and analyzing clinical and translational research.

  • Fundamentals of AI for Medical Education, Research and Practice

    • 1st Edition
    • Sameer Mohommed Khan
    • English
    Fundamentals of AI for Medical Education, Research and Practice provides a comprehensive introduction on all aspects of AI application in healthcare, ranging from medical education to diagnostic medicine. The book's chapters are grouped into six sections: an introduction to AI in healthcare, AI in medical education, AI healthcare in research, AI in clinical practice, and future directions and challenges, concluding with practical application of AI tools in health care. Written by an experienced physiologist and medical educationist who is actively involved in all aspects of teaching and learning, this book will prove to be immense benefit for medical researchers, practicing clinicians, academicians and medical students at all levels.

  • CRISPR-Cas-Based Genome Editing for Treating Human Diseases - Part B

    • 1st Edition
    • Volume 210
    • English
    CRISPR-Cas-Based Genome Editing for Treating Human Diseases, Part B represents CRISPR-Cas systems for genome editing. Currently, CRISPR-Cas systems have been proven to be a key technology for targeted genome editing, which is acting as a simple, rapid, and cost-effective solution. Chapters in this release include Current approaches in CRISPR –Cas systems for metabolic disorders, Recent progress in CRISPR –Cas systems for CRISPR for retinal diseases, Recent progress in CRISPR –Cas systems for cataract and blindness, Advances in CRISPR –Cas systems for muscular dystrophy, Recent development in CRISPR –Cas systems for cardiac disease, Current approaches in CRISPR –Cas systems for diabetes, and much more.Additional sections cover Advances in CRISPR –Cas systems for liver disease, Advances in CRISPR –Cas systems for lung disease, Advances in CRISPR –Cas systems for kidney diseases, Current progress in CRISPR –Cas systems for rare disease, Advances in CRISPR –Cas systems for heredity disease, Recent progress in CRISPR –Cas systems for neurological disorders, and CRISPR challenges in clinical developments.

  • Immuno-oncology and immunotherapy Part C

    • 1st Edition
    • Volume 191
    • English
    Immuno-oncology and immunotherapy, Part C, Volume 191 in the Methods in Cell Biology series, highlights new advances in the field, with this new volume presenting interesting chapters on a variety of timely topics, including Extraction and quantification of histones from human cells, Expression and characterization of Phosphatidylserine-t... antibodies for biochemical and therapeutic applications, ILC differentiation from HSCs in vitro, Methods to expand human Treg cells and assay their function, Monitoring rapid activation of human gamma/delta T cells by multicolor flow cytometry, Methods to induce T cell exhaustion in vitro, Ex vivo assessment of human neutrophil motility and migration, and much more.Additional chapters focus on Flow cytometry-based monitoring of myeloid-derived suppressor cells in the peripheral blood of patients with solid tumors, Deciphering human blood and tumor neutrophil heterogeneity: Methods for isolation and assessing suppression of T-cell proliferation, Splenocyte anticancer citotoxicity assessment after prophylactic vaccination or drug treatment of tumor-bearing mice, Therapeutic treatment of tumor-bearing mice with drug-killed cancer cells: a method to confirm immunogenic cell death and assess its therapeutic effectiveness, and much more.

  • Grapevine

    Added-Value and Applications
    • 1st Edition
    • Volume 113
    • English
    Grapevine: Added-Value and Applications, Volume 111 in the Advances in Botanical Research series, highlights new advances in the field, with this new volume presenting interesting chapters on exciting and timely topics such as Biorefinery based bioproducts and future prospective of vineyard and winery waste, Side-streams of wine industry: insights and learned lessons for making real the vision of reliable pharmacological applications, Grapevine as a natural resource in the cosmetic industry, Biology of the main grapevine viruses and their effects on vine growth, yield, and grape chemical composition, Table grapes: Health implications and approaches to improve the quality during the cultivation, and more.Additional sections cover topics such as Controlling authenticity throughout the wine production chain and Wine consumption versus health: the dilemma.

  • Advances in Clinical Chemistry

    • 1st Edition
    • Volume 124
    • English
    Advances in Clinical Chemistry, Volume 124 provides the fundamentals of physiologic and pathophysiologic biochemistry in general and clinical chemistry. Complex molecular pathways are elucidated using historical, current, and emerging technologies such as biosensor design and development. Identification of novel biomarkers and accurate and precise analysis are key to cutting-edge patient care, diagnostics, and treatment. This series strategically focuses on new tools for the detection of novel biomarkers, especially in light of an aging worldwide population faced with increased prevalence of chronic disease, many of which lack early diagnostic tools that are so essential to patient care and socioeconomic outcome.

  • Proteomics, Multi-Omics and Systems Biology in Optic Nerve Regeneration

    • 1st Edition
    • Sanjoy K. Bhattacharya
    • English
    Proteomics, Multi-Omics and Systems Biology in Optic Nerve Regeneration is a comprehensive reference that covers all vistas of standardization of axon regeneration, as well as all multi-omics and system level data and integration tools. By adopting a translational approach, the book bridges current research in the field to clinical applications, and readers can expect to learn standardization approaches for axon regeneration, multi-omics datasets, different databases, search engines, multiple dataset integrative tools, pathway convergence approaches and tools, outcome and outcome measures that unify bench research with clinical outcome.The axon regeneration from existing neurons in central nervous system (CNS) have become a potential possibility in the last decade. The potential possibility of long-distance axon growth has opened the possibility of re-connectivity of axons of retinal ganglion cell neurons within the lateral geniculate nucleus in the brain. The long-distance axon regeneration and re-connectivity is a promise to restore lost vision in the optic nerve. Further, long-distance regeneration and re-innervation is equally helpful for other fields such as spinal cord injuries.

  • Artificial Intelligence Applications for Brain–Computer Interfaces

    • 1st Edition
    • Abdulhamit Subasi + 3 more
    • English
    Artificial Intelligence Applications for Brain-Computer Interfaces focuses on the advancements, challenges, and prospects of future technologies involving noninvasive brain-computer interfaces (BCIs). It includes the processing and analysis of multimodal signals, integrated computation-acquisit... devices, and implantable neuro techniques. This book not only provides cross-disciplinary research in BCI but also presents divergent applications on telerehabilitation, emotion recognition, neuro-rehabilitation... cognitive workload assessments, and ambient assisted living solutions. In 15 chapters, this book describes how BCIs connect the brain with external devices like computers and electronic gadgets. It analyzes the neural signals from the brain to obtain insights from the brain patterns using multiple noninvasive wearable sensors. It gives insight into how sensor outcomes are processed through machine-intelligent models to draw inferences. Each chapter starts with the importance, problem statement, and motivation. A description of the proposed methodology is provided, and related works are also presented. Each chapter can be read independently, and therefore, the book is a valuable resource for researchers, health professionals, postgraduate students, postdoc researchers, and academicians in the fields of BCI, prosthesis, computer vision, and mental state estimation, and all those who wish to broaden their knowledge in the allied field.

  • Digital Healthcare, Digital Transformation and Citizen Empowerment in Asia-Pacific and Europe for a Healthier Society

    • 1st Edition
    • Patricia Ordonez de Pablos + 2 more
    • English
    Digital Healthcare, Digital Transformation and Citizen Empowerment in Asia-Pacific and Europe for a Healthier Society explores the potential of advanced IT in healthcare. This book shares insights on leveraging IT tools to address global disruptions like the pandemic, offering case studies from various regions, innovative topics in digital healthcare, lessons from the COVID-19 pandemic, and recommendations for policymakers worldwide. This title is a valuable resource for researchers, clinicians, CEOs, and policymakers seeking to learn from both failures and successes and harness the potential of advanced information technologies to enhance healthcare systems and services.

  • Global Oculoplastics

    A Guide to the Care of Patients in Resource-Poor Environments
    • 1st Edition
    • Morris E Hartstein + 1 more
    • English
    Global Oculoplastics provides details on addressing a large range of oculofacial plastic procedures with a focus on situations in the resource-poor setting where there may be minimal equipment or supplies. Through comprehensive descriptions, photographs, diagrams, and illustrations, practitioners will gain practical knowledge essential for providing high-quality care under challenging conditions. In addition, for those wishing to effect systemic change, there are chapters about working successfully in complicated medical situations worldwide.This book is organized into two distinct parts. Part 1 delves into the foundational aspects of global ophthalmology, addressing why cultural sensitivity, ethics, and collaboration with local partners are crucial. It also prepares professionals for working in environments with limited resources, such as unreliable electricity, water, and sterilization facilities.Part 2 shifts focus to the practical application of oculoplastic techniques. It covers various conditions encountered during global missions and offers guidance on delivering effective surgical care with limited resources and implants.This book is designed to be a critical resource for practitioners facing the daily challenges of addressing complex oculofacial issues in resource-poor settings. Its straightforward, yet thorough, "how-to" method descriptions will be particularly useful for surgeons tackling a wide range of oculoplastic conditions.

  • Endoscopy-Past, Present, and Future

    The NYSGE at 50
    • 1st Edition
    • Jonathan Cohen + 1 more
    • English
    Endoscopy-Past, Present, and Future: The NYSGE at 50 commemorates a significant milestone - the 50th Anniversary of NYSGE. In honor of this occasion, prominent voices within the Society explore pivotal advancements in the realm of gastrointestinal endoscopy, a journey that has unfolded since the group's inception in 1974. These essays intricately weave the narrative of the indispensable role NYSGE members have played in shaping the landscape. While the spotlight is cast on the pioneering strides made by NYSGE's endoscopists and researchers, the volume also examines how these breakthroughs intertwine with the contemporary state of various endoscopic disciplines.The book's chapters take readers on a comprehensive journey through the evolution of gastroenterology and endoscopy. Opening with a historical overview, the first chapter delves into the visionary founding of NYSGE and its subsequent growth. Highlighting figures like Florence Lefcourt and Doris Barnie, the chapter underscores their pivotal roles in establishing the society. It traces the development of the nurses program, NYSGE courses, and global collaborations, offering a glimpse into transformative advancements on the horizon. Following chapters spotlight pivotal achievements, such as the trajectory of polypectomy from its inception to televideo mentoring, and more.

  • How to Treat Low Back Pain

    A Guide for Treating causes of Low Back Pain for Physicians and APPs
    • 1st Edition
    • Timothy R. Deer + 1 more
    • English
    How to Treat Low Back Pain: A Guide for Treating Causes of Low Back Pain for Physicians and APPs focuses on current technology and cutting-edge treatment options, all validated by data. Each chapter presents a thorough review of patient selection, procedure technique, and potential adverse complications for each recommended treatment. Written by experts in the field for practitioners and clinicians treating low back pain, and with anatomic artwork and illustrations throughout, the book covers all aspects of lower back pain, the leading cause of disability in developed countries, with the number of people affected worldwide increasing annually.In recent years, there has been a substantial increase in health care costs to treat low back pain, and most of these treatments simply provide symptomatic relief with few strategies that actually contribute to correcting the underlying cause.

  • Kaufman’s Atlas of Mouse Development Supplement

    With Coronal Sections
    • 2nd Edition
    • Gillian Morriss-Kay + 1 more
    • English
    Kaufman's Atlas of Mouse Development Supplement, Second Edition continues the stellar reputation of the original Atlas by providing updated, in-depth anatomical content and morphological views of organ systems. The book explores the developmental origins of the organ systems, following the original atlas as a continuation of the standard in the field for developmental biologists and researchers across biological and biomedical sciences studying mouse development. In this new edition, each chapter has been updated to include the latest research, along with while new chapters on the functional aspects of mouse and human heart development, the immune system, and the inner ear.These additions ensure an up-to-date resource for all biomedical scientists who use the mouse as a model species for understanding the normal and abnormal development of human systems.

  • Interventional Management of Migraines and Other Headache Disorders

    • 1st Edition
    • Ivan Urits + 1 more
    • English
    Interventional Management of Migraines and Other Headache Disorders provides a comprehensive overview of interventional treatment options available for migraine headaches and other headache disorders, including their mechanisms of action, indications, contraindications, and efficacy. It covers the fundamental principles of interventional procedures, including patient selection, preparation, and monitoring during and after treatment. This book offers practical instructions to clinicians and healthcare professionals for the selection, administration, and evaluation of interventional treatments for headaches. Further, it addresses the multidisciplinary aspects of migraine management, including collaboration between neurologists, pain specialists, anesthesiologists, and other professionals involved in patient care.

  • Precision Medicine for Long and Safe Permanence of Humans in Space

    • 1st Edition
    • Chayakrit Krittanawong
    • English
    Precision Medicine for Long and Safe Permanence of Humans in Space serves as a reference to assist with the diagnosis of medical conditions (e.g., microgravity, space radiation), monitoring inflight, clinical decision-making inflight, disease prediction and prevention (pre- or postflight), and the facilitation of precision space medicine. This book defines the basic concepts of space health, fundamental physics, and biology in space and highlights the current applications, current challenges, and future directions in space medicine. Each chapter discusses precision medicine to a specific medical subspecialty, including cardiovascular disease, neurology, nephrology, endocrinology, ophthalmology, hepatology, hematology, pulmonology, emergency medicine, nutrition, dermatology, immunology, mental health, regenerative medicine, surgery, vascular surgery, anesthesiology, urology, OB-GYN, and male and female reproductive issues in space. Additionally, this book discusses current artificial intelligence (AI) technology in space, AI in commercial space industry, and recent space health progress worldwide (e.g., NASA, China, Japan, the Middle East). This book serves as an ideal companion for healthcare professionals, scientists, researchers, postdoctoral fellows, students, or anyone interested in space travel.

  • Protistology

    • 1st Edition
    • Sina M. Adl
    • English
    Protistology provides a comprehensive overview on recent developments in understanding the diversity of cell biology, genomic processes, parasite-host interactions, and the evolution of eukaryotes. The book is the first modern treatise on these organisms, walking readers through protistology’s diversity and classification. This book is an ideal supplemental text for upper-level undergraduates and graduate students in microbial ecology, freshwater and marine biology, soil ecology, environmental sciences, or those looking to initiate a course in protistology.

  • Sex and Gender Differences in Cardiovascular-Renal-Metabolic Physiology and Pathophysiology

    Sex, Gender and Function
    • 1st Edition
    • Jane Reckelhoff + 2 more
    • English
    Sex and Gender Differences in Cardiovascular-Renal... Physiology and Pathophysiology: Sex, Gender and Function, the latest release in the Fundamentals of Physiology series, provides a fundamental overview on sex and gender differences in all aspects of physiology. The book shares information on sex and gender differences in a variety of topics in a single comprehensive volume. This book, published in association with the International Union of Physiological Sciences acts as a primer of information scientists can build upon with their own research in sex and gender-based research.

  • Deep Learning in Genetics and Genomics

    Volume 1: Foundations and Introductory Applications
    • 1st Edition
    • Khalid Raza
    • English
    Deep Learning in Genetics and Genomics vol. 1, Foundations and Applications, the intersection of deep learning and genetics opens up new avenues for advancing our understanding of the genetic code, gene regulation, and the broader genomics landscape. The book not only covers the most up-to-date advancements in the field of deep learning in genetics and genomics, but also a wide spectrum of (sub) topics including medical and clinical genetics, predictive medicine, transcriptomic, and gene expression studies. In 21 chapters Deep Learning in Genetics and Genomics vol. 1, Foundations and Applications describes how AI and DL have become increasingly useful in genetics and genomics research where both play a crucial role by accelerating research, improving the understanding of the human genome, and enabling personalized healthcare. From the fundamentals concepts and practical applications of deep learning algorithms to a wide range of challenging problems from genetics and genomics, Deep Learning in Genetics and Genomics vol. 1, Foundations and Applications creates a better knowledge of the biological and genetics mechanisms behind disease illnesses and improves the forecasting abilities using the different methodologies described. This title offers a unique resource for wider, deeper, and in-depth coverage of recent advancement in deep learning-based approaches in genetics and genomics, helping researchers process and interpret vast amounts of genetic data, identify patterns, and make discoveries that would be challenging or impossible using traditional methods.

  • Deep Learning in Genetics and Genomics

    Volume 2: Advanced Applications
    • 1st Edition
    • Khalid Raza
    • English
    Deep Learning in Genetics and Genomics: Vol. 2 (Advanced Applications) delves into the Deep Learning methods and their applications in various fields of studies, including genetics and genomics, bioinformatics, health informatics and medical informatics generating the momentum of today's developments in the field. In 25 chapters this title covers advanced applications in the field which includes deep learning in predictive medicines), analysis of genetic and clinical features, transcriptomics and gene expression patterns analysis, clinical decision support in genetic diagnostics, deep learning in personalised genomics and gene editing, and understanding genetic discoveries through Explainable AI. Further, it also covers various deep learning-based case studies, making this book a unique resource for wider, deeper, and in-depth coverage of recent advancement in deep learning based approaches. This volume is not only a valuable resource for health educators, clinicians, and healthcare professionals but also to graduate students of genetics, genomics, biology, biostatistics, biomedical sciences, bioinformatics, and interdisciplinary sciences.

  • Mitophagy in Health and Disease

    Mechanisms, Health Implications, and Therapeutic Opportunities
    • 1st Edition
    • John J. Lemasters
    • English
    Mitophagy in Health and Disease: Mechanisms, Health Implications, and Therapeutic Opportunities is a complete reference to this key cellular process involved in homeostasis. The book addresses the machinery and mechanisms of mitophagy, including an overview of mito-biogenesis and dynamics and specific types of mitophagy. Other sections cover mitophagy across the human lifespan, from development to aging, discussing the interplay between inflammation and several conditions. The final part covers therapeutic opportunities presented by targeting mitophagy, including inducers and inhibitors, targeting strategies, and studies specific to cardioprotection and neurodegenerative diseases prevention.This is the ideal reference for cellular and molecular biologists needing a consistent and thorough overview of the subject, as well as research physicians in areas where mitochondria play a key role.

  • Time-Resolved Methods in Structural Biology

    • 1st Edition
    • Volume 709
    • English
    Time-Resolved Methods in Structural Biology series, highlights new advances in the field, with this new volume presenting interesting chapters. Each chapter is written by an international board of authors.

  • Advances in Biomembranes and Lipid Self-Assembly

    • 1st Edition
    • Volume 40
    • English
    Advances in Biomembranes and Lipid Self-Assembly, Volume 40 highlights new advances in the field, with this new volume presenting interesting chapters written by an international board of authors.

  • T Cell Metabolism and Cancer Immunotherapy

    • 1st Edition
    • Jianxun Song
    • English
    T Cell Metabolism and Cancer Immunotherapy delves into the intricate regulation of T-cell immunity and tolerance. As research advances in cell-based therapies, the potential of engineered immune cells to treat cancers and other diseases is becoming increasingly evident due to their powerful capabilities. Additionally, the book offers valuable insights into developing and optimizing strategies for bacterium-based immunotherapies. Despite great advancement in immunotherapy such as adoptive T cell transfer-based regimen, the clinical outcomes remain less satisfactory due to a variety of factors that lessen its therapeutic efficacy. By determining the role and importance of T cell metabolism in the regulation of T lymphocytes that are related to the development and managements of aberrant immunity, T Cell Metabolism and Cancer Immunotherapy designs and develops novel and more effective strategies for improving regimens for patients with aberrant immunity. Within ten chapters the content not only reveals targets of T cell metabolism as critical determinants of immune regulation, but also uncovers unique therapeutic opportunities to improve immunotherapy through targeting T cell metabolism. This fills a significant gap in the knowledge of scientists working in the field of onco-immunology/immu... and students learning about T cells, metabolism, immunomodulation, and immunotherapy.

  • Electrocardiography of Channelopathies

    A Primer for the Clinical Cardiologist
    • 1st Edition
    • Manlio F. Márquez-Murillo
    • English
    Electrocardiography of Channelopathies: A Primer for the Clinical Cardiologist introduces readers to the inherited arrhythmia syndromes that are a leading cause of sudden cardiac death. As the ECG is the cornerstone of identifying inherited arrhythmia syndromes, this cutting-edge book is a critical resource to guide cardiologists in using the technology for optimum diagnosis and treatment of their patients. It clearly delineates the differences between each syndrome to improve accuracy and health outcomes. Its easy portability belies a vast knowledge base for use by clinicians in the moment as well as by researchers in the laboratory.This book illuminates diseases such as Short and Long QT Syndromes, Andersen-Tawil Syndrome, Brugada Syndrome, Polymorphic Ventricular Tachycardia, and Early Repolarization syndrome. Electrocardiography of Channelopathies: A Primer for the Clinical Cardiologist will no doubt become a go-to reference for experienced clinicians seeking confirmation of their diagnoses, as well as those newer to the field seeking guidance in ECG interpretation.

  • Digital Pathology

    Implementation in Clinical Practice with AI applications
    • 1st Edition
    • Meera Hameed + 1 more
    • English
    Digital Pathology: Implementation in Clinical Practice with AI Applications covers digital pathology applications in a clinical pathology laboratory setting, providing guidance and various tools for practical implementation. This comprehensive and detailed description of nuts and bolts of digital pathology implementation is unique and comes from the experience of high throughput scanning from a large surgical pathology laboratory. This is a valuable reference to prepare the end users not only about thoughtful launch of digital pathology but also to prepare for the future use of AI mediated decision support tools as the field advances.This book covers the entire range of this topic and can be used as a practical reference for individuals that wish to be part of the evolution of diagnostic pathology. Sections include pre-analytic, analytic, and post-analytic processes, encompassing hardware, software, space, staffing, quality control, laboratory information system applications, clinical validation, use cases and future applications, including computer assisted diagnosis and decision support tools.

  • Immune Therapy for Pancreatic and Colon Cancers

    • 1st Edition
    • Ganji Purnachandra Nagaraju + 2 more
    • English
    Immune Therapy for Pancreatic and Colon Cancer expands the knowledge on pathways, immune modulators, immune check points, and monoclonal antibodies that can lead to appropriate cancer treatment. With a strong focus on the development of immune therapies to improve the survival rates of pancreatic and colon cancer, this book also shows the latest trends in immune targeted approaches for cancer treatment. Sections describe the role of and the immune response to pancreatic and colon cancer, gives insights to past and current immunotherapies, including metabolic reprogramming, immune blockade therapy and immune modulation.This book is a valuable resource for health professionals, scientists and researchers, students, and all those who wish to broaden their knowledge of the advances in immunotherapy in pancreatic and colon cancer, inspire them and guide their design of novel experimental projects and translational studies.

  • Lanthanides in Enzymology and Microbiology

    • 1st Edition
    • Akio Tani + 2 more
    • English
    Lanthanides in Enzymology and Microbiology, a new volume in the Foundations and Frontiers in Enzymology Series, offers a detailed discussion of lanthanides and lanthanide-dependent enzyme biology. In this book, more than a dozen global experts consider lanthanide enzymology fundamentals, organismal utilization of lanthanides, distribution and diversity of lanthanide-dependent enzymes, regulation of intracellular levels of lanthanides, gene expression regulation via lanthanides, as well as likely applications of lanthanide binding proteins. Lanthanide-dependent methanol and alcohol dehydrogenase metabolism are considered in both methylotrophs and non-methylotrophs, alongside various application areas, from recovery of rare earth elements to developing lanthanide ion binding peptides and biosynthesis of terpolymers through reverse-oxidation pathways. In providing this deep context and pathways for future research, this book acts as an invaluable resource in this emerging field for researchers and students of biochemistry, biotechnology, and environmental microbiology alike.

  • Gait, Balance, and Mobility Analysis

    Theoretical, Technical, and Clinical Applications
    • 1st Edition
    • Samuel Stuart + 1 more
    • English
    Gait, Balance, and Mobility Analysis: Theoretical, Technical, and Clinical Applications provides a comprehensive overview of gait and movement analysis techniques, from traditional motion capture to modern wearable technologies. The book contains both a technical element that focuses on biomechanics and engineering concepts for gait analysis and the application of gait analysis with clinical populations. Beginning with a comprehensive background on the underlying neural control of gait and mobility in humans and physiological control of balance, the book then covers analysis methods and techniques for laboratory, clinic or remote patient assessment.It then examines how gait, mobility and balance are impacted by musculoskeletal, neurological, and cardio-respiratory conditions. Lastly, it discusses future directions and provides recommendations for future studies. Combining the expertise of engineers and clinicians, this book takes a multidisciplinary approach to show how and why gait, balance and mobility can be used to tackle important clinical questions for various conditions.

  • Artificial Intelligence in Urologic Malignancies

    • 1st Edition
    • Himanshu Arora
    • English
    Artificial Intelligence in Urologic Malignancies describes current artificial intelligence technology, with an emphasis on prostate cancer applications. The book provides guidance on how artificial intelligence can improve therapeutics, how the power of artificial intelligence integrated with current standard therapy and research can enhance decision-making, and proposes future directions on how to integrate artificial intelligence within clinical applications. This is the perfect reference for scientists and researchers interested in the basic translational research opportunities such as drug discovery, pharmacogenetics, and experimental therapeutics, as well as clinicians interested in how AI applications are integrated with applications.

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