Role of Sex and Gender in Aging and Longevity
- 1st Edition - August 6, 2025
- Imprint: Academic Press
- Editor: Calogero Caruso
- Language: English
- Paperback ISBN:9 7 8 - 0 - 4 4 3 - 2 7 3 9 8 - 8
- eBook ISBN:9 7 8 - 0 - 4 4 3 - 2 7 3 9 9 - 5
Role of Sex and Gender in Aging and Longevity aims to shed light on the complex interplay between sex and gender differences in the aging process and longevity of indivi… Read more
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Role of Sex and Gender in Aging and Longevity aims to shed light on the complex interplay between sex and gender differences in the aging process and longevity of individuals. While biological sex differences have long been recognized as influencing various aspects of aging, this book includes how gender also plays a significant role in shaping these processes, accelerating aging, or favoring longevity. By acknowledging the influence of both biological and socially constructed factors, this book offers a comprehensive understanding of why individuals may experience different aging trajectories and have divergent longevity outcomes. This book explores the intricate ways in which gender norms, roles, and expectations shape individual experiences of aging and delves into the social determinants of health that can interact with biological factors to influence the aging process and longevity outcomes. By examining these interactions, this book aims to provide a nuanced understanding of the multifaceted nature of aging and longevity and how sex and gender contribute to these complex phenomena, laying the groundwork for future aging research and providing significant implications for disease prevention, screening, diagnosis, and treatment of age-related conditions.
• Explores the distinct significance of sex and gender and their interrelation with aging and longevity
• Offers an in-depth overview of the sex- and gender-specific biological and medical aspects of human aging and longevity
• Provides the tools required to understand the challenges posed by aging and longevity in individuals and how to approach solving them
• Offers an in-depth overview of the sex- and gender-specific biological and medical aspects of human aging and longevity
• Provides the tools required to understand the challenges posed by aging and longevity in individuals and how to approach solving them
Both basic and applied researchers in aging, age-related diseases, and longevity
1. Role of sex and gender in aging and longevity: An introduction
2. Sex and longevity: A demographic perspective
3. Exposome, aging, and longevity: The role of sex and gender differences in health and mortality
4. The health-survival paradox: Women live longer but are frailer
5. Lifestyle and successful aging in men and women
6. Role of genetics and hormones in the differences in longevity between men and women
7. Sex, gender, and epigenetics of aging and longevity
8. Hormesis and sex factors in aging and central nervous system disorders
9. The role of sex and gender in the proinflammatory status in aging and longevity
10. Immune aging of men and women: Different susceptibility to infectious diseases and different response to vaccines
11. The role of sex and age in some pathobiological and pathophysiological processes
12. Sex and gender differences in pathophysiology, clinical aspects, and drug therapy. Focus on oncology
13. Sex and gender differences in cardiovascular diseases
14. Brain aging, neurodegenerative disorders, and sex differences
15. Endocrine disorders in male and female older people
16. Autoimmune diseases of older people are influenced by sex and gender
17. Allergic diseases: Differences related to sex and gender and age
18. Sex differences in biomarkers: Implications for age-related diseases
19. Laboratory parameters in male and female older people
20. Role of sex and gender in aging and longevity: State of the art and future perspectives
2. Sex and longevity: A demographic perspective
3. Exposome, aging, and longevity: The role of sex and gender differences in health and mortality
4. The health-survival paradox: Women live longer but are frailer
5. Lifestyle and successful aging in men and women
6. Role of genetics and hormones in the differences in longevity between men and women
7. Sex, gender, and epigenetics of aging and longevity
8. Hormesis and sex factors in aging and central nervous system disorders
9. The role of sex and gender in the proinflammatory status in aging and longevity
10. Immune aging of men and women: Different susceptibility to infectious diseases and different response to vaccines
11. The role of sex and age in some pathobiological and pathophysiological processes
12. Sex and gender differences in pathophysiology, clinical aspects, and drug therapy. Focus on oncology
13. Sex and gender differences in cardiovascular diseases
14. Brain aging, neurodegenerative disorders, and sex differences
15. Endocrine disorders in male and female older people
16. Autoimmune diseases of older people are influenced by sex and gender
17. Allergic diseases: Differences related to sex and gender and age
18. Sex differences in biomarkers: Implications for age-related diseases
19. Laboratory parameters in male and female older people
20. Role of sex and gender in aging and longevity: State of the art and future perspectives
- Edition: 1
- Published: August 6, 2025
- Imprint: Academic Press
- Language: English
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Calogero Caruso
Calogero Caruso is Professor Emeritus in the Department of Biomedicine, Neurosciences and Advanced Diagnostics at the University of Palermo. He has authored over 415 papers, mostly on ageing, age-related diseases, and longevity. He was founder and editor in chief of Immunity & Ageing from 2004 to 2018, Coordinator of the PhD program in Molecular Medicine and Biotechnology (formerly Pathobiology) from 1998-2018, and National Coordinator of Italian Ministerial Project on Centenarians and Longevity from 2016-2019. Finally, with Prof. Giuseppina Candore he is responsible for the local unit of the project “Improved Vaccination Strategies for Older Adults (ISOLDA)” funded by the European Commission. The national and international recognition of his scientific achievements in the field of Biogerontology is documented by funded projects, by the number of citations of his papers, by invitations to national and international congresses and meetings, by his activity as a project reviewer and by organization of international conferences.
Affiliations and expertise
Professor Emeritus, Department of Biomedicine, Neurosciences and Advanced Diagnostics, University of Palermo, ItalyRead Role of Sex and Gender in Aging and Longevity on ScienceDirect