Autoimmune Hemolytic Anemias
A Practical Guide
- 1st Edition - July 10, 2025
- Latest edition
- Authors: Wilma Barcellini, Bruno Fattizzo
- Language: English
Autoimmune Hemolytic Anemias: A Practical Guide is a comprehensive update of autoimmune hemolytic anemias, a rare disease that is sometimes difficult to diagnose and manage. This b… Read more
Autoimmune Hemolytic Anemias: A Practical Guide is a comprehensive update of autoimmune hemolytic anemias, a rare disease that is sometimes difficult to diagnose and manage. This book describes diagnosis, pathogenesis, classification, standard therapy, new treatments, as well as secondary forms, such as lymphoproliferative, immunodeficiency, Evans, and other autoimmune diseases. It is a practical guide to manage transfusions and monitoring complications, such as infections and thromboses, and preventive measures. This book is useful to researchers, clinicians, doctors and students working in hematology, transfusion centers, immunohematology labs, and internal medicine.
- Chapters include clinical case vignettes that discuss special situations such as pregnancy, acute settings, complications, and difficult cases for diagnosis and treatment
- Chapters include a summary or key points and practical recommendations
- Provides an overview of signs and symptoms of AIHA with a special attention to various subtypes including patient-reported outcomes
- Presents AIHA clinical and laboratory diagnosis, with focus on the differential diagnosis of hemolysis (kw Coombs, direct antiglobulin test, hemolytic markers, etc.)
Hematologist, immunologist, transfusionists, internists, Doctors and students working in Hematology, transfusion centers, immunohematology labs, internal medicine, pediatrics, clinical immunology, rheumatology, ICU
1. Introduction
2. Diagnosis of autoimmune hemolytic anemias and differential diagnosis of hemolysis
3. Classification of autoimmune hemolytic anemias
4. Clinical presentation of autoimmune hemolytic anemias
5. Standard treatment of autoimmune hemolytic anemias
6. Novel treatment strategies of autoimmune hemolytic anemias
7. Complications of AIHAs
8. Management of special situations
9. Conclusion
2. Diagnosis of autoimmune hemolytic anemias and differential diagnosis of hemolysis
3. Classification of autoimmune hemolytic anemias
4. Clinical presentation of autoimmune hemolytic anemias
5. Standard treatment of autoimmune hemolytic anemias
6. Novel treatment strategies of autoimmune hemolytic anemias
7. Complications of AIHAs
8. Management of special situations
9. Conclusion
- Edition: 1
- Latest edition
- Published: July 10, 2025
- Language: English
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Wilma Barcellini
Wilma Barcellini, an Associate Professor specializing in Blood Diseases, Oncology, and Rheumatology, serves as Director of the Pathophysiology of Anemia Unit at IRCCS Ospedale Maggiore Policlinico Foundation. She specializes in diagnosing and treating immuno-mediated cytopenias and rare anemias. Barcellini leads Research Projects funded by renowned institutions like IRCCS Ospedale Maggiore Policlinico Foundation, Istituto Superiore di Sanità, and the Ministry of Health. She's a distinguished member of the European Network for Rare and Congenital Anemias. In the 1980s and 1990s, she gained experience as a Visiting Scientist at the Laboratories of Immunology under Professors RH Zubler at the University Hospital Geneva, Switzerland, and A Dalgleish at St George's Hospital, University of London, UK.
Affiliations and expertise
IRCCS Ospedale Maggiore Policlinico Foundation, ItalyBF
Bruno Fattizzo
Bruno Fattizzo, a dedicated Hematologist and Assistant Professor at Policlinico Hospital and the University of Milan, Italy, centers his clinical and research endeavors on autoimmune cytopenias, notably autoimmune hemolytic anemia (AIHA), immune thrombocytopenia, autoimmune neutropenia, and Evans syndrome. His focus extends to bone marrow failure syndromes like paroxysmal nocturnal hemoglobinuria (PNH), aplastic anemia, and myelodysplastic syndromes (MDS). During a research stint at King's College Hospital in London, Fattizzo delved into bone marrow failure syndromes, specifically exploring the clinical and prognostic implications of small PNH clones. He boasts an authorship of over 135 publications in indexed journals. Fattizzo also spearheads clinical trials involving innovative drugs tailored for AIHA, PNH, and MDS, showcasing his commitment to advancing treatment modalities in these conditions.
Affiliations and expertise
IRCCS Ospedale Maggiore Policlinico Foundation and University of Milano, ItalyRead Autoimmune Hemolytic Anemias on ScienceDirect