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Elsevier

Books in Life sciences

  • Recent Advances in iPSC Disease Modeling

    • 1st Edition
    • Alexander Birbrair
    • English
    Recent Advances in iPSC Disease Modeling, Volume One addresses how induced pluripotent stem cells can be used to model various diseases. This new volume teaches readers about current advances in the field, describing the use of induced pluripotent stem cells to model several diseases in vitro, and thus enabling us to study the cellular and molecular mechanisms involved in different pathologies. Further insights into these mechanisms will have important implications for our understanding of disease appearance, development and progression. The volume is written for researchers and scientists in stem cell therapy, cell biology, regenerative medicine and organ transplantation specialists. In recent years, remarkable progress has been made in the obtention of induced pluripotent stem cells and their differentiation into several cell types, tissues and organs using state-of-art techniques. Hence, these advantages have facilitated the identification of key targets and further defining on the molecular basis of several disorders.

  • Kidney Biomarkers

    Clinical Aspects and Laboratory Determination
    • 1st Edition
    • Seema S. Ahuja + 1 more
    • English
    Since laboratory testing and biomarkers are an integral part in the diagnosis and treatment of kidney disease, Kidney Biomarkers: Clinical Aspects and Laboratory Determination covers currently used biomarkers as well as markers that are in development. Laboratories are increasingly more involved in the follow-up confirmatory laboratory testing and this unique volume showcases the collaboration needed to solve diagnostic clinical puzzles between the laboratory and clinician. This volume provides guidance on laboratory test selection and results interpretation in patients. Sources of inaccurate results in the measurement of kidney biomarkers are discussed along with possibility of eliminating such interferences. Each chapter is organized with a uniform easy-to-follow format with insightful case examples highlighting the collaboration between clinical laboratorians and clinicians.

  • Biodiversity and Biomedicine

    Our Future
    • 1st Edition
    • Munir Ozturk + 2 more
    • English
    Biodiversity and Biomedicine: Our Future provides a new outlook on Earth’s animal, plant, and fungi species as vital sources for human health treatments. While there are over 10 million various species on the planet, only 2 million have been discovered and named. This book identifies modern ways to incorporate Earth’s species into biomedical practices and emphasizes the need for biodiversity conservation. Written by leading biodiversity and biomedical experts, the book begins with new insights on the benefits of biologically active compounds found in fungi and plants, including a chapter on the use of wild fruits as a treatment option. The book goes on to discuss the roles of animals, such as amphibians and reptiles, and how the threatened presence of these species must be reversed to conserve biodiversity. It also discusses marine organisms, including plants, animals, and microbes, as essential in contributing to human health. Biodiversity and Biomedicine: Our Future is a vital source for researchers and practitioners specializing in biodiversity and conservation studies. Students in natural medicine and biological conservation will also find this useful to learn of the world’s most bio-rich communities and the molecular diversity of various species.

  • A Comprehensive Overview of Irritable Bowel Syndrome

    Clinical and Basic Science Aspects
    • 1st Edition
    • Jakub Fichna
    • English
    A Comprehensive Overview of Irritable Bowel Syndrome: Clinical and Basic Science Aspects presents up-to-date knowledge in the field and provides a comprehensive summary of this area of study, including an overview on IBS, starting from its pathogenesis, including genetic, microbial and physiological background, through symptom recognition, diagnosis and IBS treatment, both non-pharmacological and pharmacological.

  • Obesity

    Global Impact and Epidemiology
    • 1st Edition
    • Raman Mehrzad
    • English
    Obesity continues to accelerate resulting in an unprecedented epidemic that shows no significant signs of slowing down any time soon. The World Health Organization reports that in 2016, nearly 2 billion adults were overweight and that worldwide obesity has nearly tripled since 1975. Obesity: Global Impact and Epidemiology is an important tool in proving a link to new knowledge, serving researchers and clinicians. The field of obesity is evolving very quickly and there is an abundance of scientific data that has emerged and is emerging constantly. Researchers and physicians need new updated information about the epidemiology and global impact of obesity that come from authors that have a wide perspective in the field. For health professionals and researchers, there is a need to understand how obesity begins. While a simple question, the answer is very complex.

  • Weed Science

    Cannabis Controversies and Challenges
    • 1st Edition
    • Godfrey Pearlson
    • English
    WHAT DO WE KNOW ABOUT MARIJUANA AND HOW DO WE KNOW IT? Marijuana is the most frequently consumed illicit drug worldwide, with over 158.8 million users, according to the UN. Responding to public pressure, the US federal government is likely to legalize recreational marijuana within the next few years. With increasing numbers of people using cannabis both medically and recreationally there are many looming questions that only science can answer. These include: What's likely to happen, both good and bad, if the US legalizes marijuana? What are some simple, science-based rules to separate fact from fiction and to help guide policy in the highly contentious marijuana debate? Exactly what is cannabis doing in the brain that gets us high? A journey through THC neuroscience Does cannabis really have medical benefits - what's the evidence? To what extent does cannabis impair driving? Can smoking marijuana in adolescence affect IQ or risk for developing schizophrenia? Is marijuana safe to use during pregnancy?

  • Human Brainstem

    Cytoarchitecture, Chemoarchitecture, Myeloarchitecture
    • 1st Edition
    • George Paxinos + 2 more
    • English
    Human Brainstem: Cytoarchitecture, Chemoarchitecture, Myeloarchitecture explores how the human brainstem has been impeded by the unavailability of an up-to-date, comprehensive, diagrammatic and photographic atlas. Now, with the first detailed atlas on the human brainstem in more than twenty years, this book presents an accurate, comprehensive and convenient reference for students, researchers and pathologists.

  • Systems and Synthetic Metabolic Engineering

    • 1st Edition
    • Yanfeng Liu + 2 more
    • English
    Systems and Synthetic Metabolic Engineering provides an overview of the development of metabolic engineering within medicine that is fueled by systems and synthetic biology. These newly developed, successful strategies of metabolic engineering guide the audience on how to propose and test proper strategies for metabolic engineering research. In addition to introductory, regulatory and challenges in the field, the book also covers dynamic control and autonomous regulation to control cell metabolism, along with computational modeling and industrial applications. The book is written by leaders in the field, making it ideal for synthetic biologists, researchers, students and anyone working in this area.

  • Biomarkers for Traumatic Brain Injury

    • 1st Edition
    • Alan H.B. Wu + 1 more
    • English
    Biomarkers for Traumatic Brain Injury provides a comprehensive overview on the selection and implementation of serum-based and saliva-based biomarkers for traumatic brain injury. The book presents an economic analysis for implementing TBI biomarkers into clinical practice. In addition, it discusses the analytical tools needed to implement TBI biomarkers, including specifications for testing instruments and interpretative software. Neurologists, emergency department physicians, intensivists, and clinical laboratorians will find this book a great resource from which to familiarize themselves with the issues and processes regarding TBI biomarkers. Approximately 2 million people in the U.S. sustain a traumatic brain injury (TBI) each year with over 250,000 hospitalizations and 50,000 deaths. There has been a significant rise in interest in diagnosing mild concussions, particularly in the sports world. While imaging has been the gold standard, these procedures are costly and not always available. There is great potential in using serum-based biomarkers, hence the book seeks to enlighten readers on new possibilities.

  • Sex and Cardiac Electrophysiology

    Differences in Cardiac Electrical Disorders Between Men and Women
    • 1st Edition
    • Marek Malik
    • English
    Sex and Cardiac Electrophysiology: Differences in Cardiac Electrical Disorders Between Men and Women is a comprehensive investigation into all aspects of sex differences in cardiac electrophysiology. As there are substantial differences between female and male patients in physiology, pathology triggering factors, disease progression, clinical approaches and treatment outcome, this book provides a comprehensive examination. In cardiology, the differences between women and men are more recognized, hence this title summarizes these important differences, providing the essential information needed for clinical specialists and researchers involved in the design and implementation of clinical studies.

  • Biometals in Autism Spectrum Disorders

    • 1st Edition
    • Andreas Grabrucker
    • English
    Biometals in Autism Spectrum Disorders focuses on trace metals and autism. Compared to other references examining ASDs or metallomics, this book presents findings of abnormal metal homeostasis in ASD, providing an overview of current findings on trace metal biology, its role in ASD etiology, and how abnormal trace metal biology may be a common factor of several genetic and non-genetic causes of ASDs that were once considered unrelated. This comprehensive resource opens new vistas for the development of new therapies based on the targeted manipulation of trace metal homeostasis that will generate new awareness surrounding trace metal levels during pregnancy.

  • Logic and Critical Thinking in the Biomedical Sciences

    Volume 2: Deductions Based Upon Quantitative Data
    • 1st Edition
    • Jules J. Berman
    • English
    All too often, individuals engaged in the biomedical sciences assume that numeric data must be left to the proper authorities (e.g., statisticians and data analysts) who are trained to apply sophisticated mathematical algorithms to sets of data. This is a terrible mistake. Individuals with keen observational skills, regardless of their mathematical training, are in the best position to draw correct inferences from their own data and to guide the subsequent implementation of robust, mathematical analyses. Volume 2 of Logic and Critical Thinking in the Biomedical Sciences provides readers with a repertoire of deductive non-mathematical methods that will help them draw useful inferences from their own data.Volumes 1 and 2 of Logic and Critical Thinking in the Biomedical Sciences are written for biomedical scientists and college-level students engaged in any of the life sciences, including bioinformatics and related data sciences.

  • Visually Memorable Neuroanatomy for Beginners

    • 1st Edition
    • Min Suk Chung + 1 more
    • English
    Visually Memorable Neuroanatomy for Beginners takes a close look at the anatomy of the human brain and teaches readers to identify and examine its structures in a relatable way. Unlike large textbooks that deliver a superficial overview of the subject, this book explores the anatomy and physiology of the brain using mnemonic techniques and informative comic figures that present brain regions at an introductory level, allowing readers to easily identify different parts of the brain. This volume is appropriate for undergraduate and graduate students, postdoctoral fellows, and researchers in the medicine, health sciences, and biological sciences. Beginning with the morphology of the brain and spinal cord, this book then explores the somatic nerve and autonomic nerve, the cranial nerve and spinal nerve, the function of the brain, and concludes with the development of the nervous system.

  • The Mediterranean Diet

    An Evidence-Based Approach
    • 2nd Edition
    • Victor R. Preedy + 1 more
    • English
    The Mediterranean Diet: An Evidence-Based Approach, Second Edition provides authoritative material on the many facets surrounding the complex interrelationships between diet, nutrition, health and well-being. The book discusses historical, cultural and scientific foundations, with chapters delving into nutritional adequacy, agricultural practices, food culture, mortality, quality of life, children and adolescents, behavior, cardiovascular diseases, diet quality, nutritional knowledge, nuts, minerals, olive oil, hydroxytyrosol, water, antioxidant nutritional status, ketogenics, adiposity, metabolic syndrome, type 2 diabetes, cardiovascular risk, nutrigenetics, epigenetics, the link between epigenetics and pregnancy, gene polymorphisms bone health, insulin signaling inflammatory gene expression, and more.

  • Statistics in Medicine

    • 4th Edition
    • Robert H. Riffenburgh + 1 more
    • English
    Statistics in Medicine, Fourth Edition, helps medical and biomedical investigators design and answer questions about analyzing and interpreting data and predicting the sample size required to achieve useful results. It makes medical statistics easy for the non-biostatistician by outlining common methods used in 90% of medical research. The text covers how to plan studies from conception to publication, what to do with data, and follows with step-by-step instructions for biostatistical methods from the simplest levels, to more sophisticated methods now used in medical articles. Examples from almost every medical specialty, and from dentistry, nursing, pharmacy and health care management are provided. This book does not require background knowledge of statistics or mathematics beyond high school algebra and provides abundant clinical examples and exercises to reinforce concepts. It is a valuable source for biomedical researchers, healthcare providers and anyone who conducts research or quality improvement projects.

  • Logic and Critical Thinking in the Biomedical Sciences

    Volume I: Deductions Based Upon Simple Observations
    • 1st Edition
    • Jules J. Berman
    • English
    Science is not a collection of facts. Science is the process by which we draw inferences from facts. Volume I of Logic and Critical Thinking in the Biomedical Sciences invites readers to linger over a collection of common observations to see what inferences can be drawn, when one applies a bit of deductive logic. If we just think about what we observe, it is often possible to discover profound biomedical insights.Volumes 1 and 2 of Logic and Critical Thinking in the Biomedical Sciences are written for biomedical scientists and college-level students engaged in any of the life sciences, including bioinformatics and related data sciences.

  • Epigenetics Methods

    • 1st Edition
    • Volume 18
    • Trygve O. Tollefsbol
    • English
    In recent years, the field of epigenetics has grown significantly, driving new understanding of human developmental processes and disease expression, as well as advances in diagnostics and therapeutics. As the field of epigenetics continues to grow, methods and technologies have multiplied, resulting in a wide range of approaches and tools researchers might employ. Epigenetics Methods offers comprehensive instruction in methods, protocols, and experimental approaches applied in field of epigenetics. Here, across thirty-five chapters, specialists offer step-by-step overviews of methods used to study various epigenetic mechanisms, as employed in basic and translational research. Leading the reader from fundamental to more advanced methods, the book begins with thorough instruction in DNA methylation techniques and gene or locus-specific methylation analyses, followed by histone modification methods, chromatin evaluation, enzyme analyses of histone methylation, and studies of non-coding RNAs as epigenetic modulators. Recently developed techniques and technologies discussed include single-cell epigenomics, epigenetic editing, computational epigenetics, systems biology epigenetic methods, and forensic epigenetic approaches. Epigenetics methods currently in-development, and their implication for future research, are also considered in-depth. In addition, as with the wider life sciences, reproducibility across experiments, labs, and subdisciplines is a growing issue for epigenetics researchers. This volume provides consensus-driven methods instruction and overviews. Tollefsbol and contributing authors survey the range of existing methods; identify best practices, common themes, and challenges; and bring unity of approach to a diverse and ever-evolving field.

  • State of the Art Evaluation of the Head and Neck, An Issue of Neuroimaging Clinics of North America

    • 1st Edition
    • Volume 30-3
    • Ashok Srinivasan
    • English
    This issue of Neuroimaging Clinics of North America focuses on State of the Art Evaluation of the Head and Neck and is edited by Dr. Ashok Srinivasan. Articles will include: Diffusion MR in the head and neck: Principles and applications; Perfusion imaging in the head and neck: Go with the flow; MR spectroscopy of the head and neck: Principles, applications and challenges; Technological improvements in head and neck MR: At the cutting edge; Dual Energy CT in head and neck imaging: Pushing the envelope; Role of Ultrasound in head and neck evaluation; PET imaging in the head and neck: Current state and future directions; Patient centric head and neck cancer radiation therapy: Role of advanced imaging; AI in head and neck imaging: Glimpse into the future; NIRADS: Principles and implementation; Common data elements in head and neck reporting; and more!

  • Novel Therapies in Head and Neck Cancer: Beyond the Horizon

    • 1st Edition
    • Volume 9
    • Maie A. St. John + 1 more
    • English
    Novel Therapies in Head and Neck Cancer: Beyond the Horizon, Volume Twelve, provides a high-level synthesis of the latest treatments and outcomes relating to head and neck cancer. Chemotherapy and immunotherapy for those cancer types are rapidly evolving, and an updated source based on the expertise of internationally renowned researchers is necessary. This book discusses the outcome of recent trials using chemotherapy, novel approaches for HPV+ SCCA, cases in which immunotherapy is more likely to be successful, and precision medicine based on target therapies. Additionally, new approaches for rare diseases in head and neck and novel drug delivery platforms are presented. This book will be a very useful source so that students, scientists and clinicians who can be facile with the data, build on what is known, and continue to offer cutting-edge, validated therapies to all patients.

  • Managing Health in the Genomic Era

    A Guide to Family Health History and Disease Risk
    • 1st Edition
    • Vincent Henrich + 2 more
    • English
    In Managing Health in the Genomic Era: A Guide to Family Health History and Disease Risk, Drs. Vincent C. Henrich, Lori A. Orlando, and Brian H. Shirts discuss the practical considerations surrounding the use of genomic and genetic tests to manage patient health, to provide adult disease risk assessment, to improve diagnosis, and to support effective interventions and treatment. In 10 chapters, evidence-based information and case studies are described and examine the central place of family health history (FHH) in genomic medicine, tools and strategies for compiling and analyzing family health history, how to identify existing and novel genetic markers, how to identify lineage specific (or rare) variants within families, and how to find effective interventions based on genetic testing results and FHH. Factors that influence clinical practice, including gene-environment interactions, FHH social networking, direct to consumer (DTC) genetic testing and data sharing, algorithms for analyzing genetic data, and patient counseling are discussed from the standpoint of clinical practice. Here, frontline healthcare providers will discover succinct commentary and key examples to assist with their local needs. Relevant principles of genetic biology and inheritance are explored and guidance on available support networks and online resources is also provided.

  • Intelligence-Based Medicine

    Artificial Intelligence and Human Cognition in Clinical Medicine and Healthcare
    • 1st Edition
    • Anthony C. Chang
    • English
    Intelligence-Based Medicine: Data Science, Artificial Intelligence, and Human Cognition in Clinical Medicine and Healthcare provides a multidisciplinary and comprehensive survey of artificial intelligence concepts and methodologies with real life applications in healthcare and medicine. Authored by a senior physician-data scientist, the book presents an intellectual and academic interface between the medical and the data science domains that is symmetric and balanced.The content consists of basic concepts of artificial intelligence and its real-life applications in a myriad of medical areas as well as medical and surgical subspecialties. It brings section summaries to emphasize key concepts delineated in each section; mini-topics authored by world-renowned experts in the respective key areas for their personal perspective; and a compendium of practical resources, such as glossary, references, best articles, and top companies.The goal of the book is to inspire clinicians to embrace the artificial intelligence methodologies as well as to educate data scientists about the medical ecosystem, in order to create a transformational paradigm for healthcare and medicine by using this emerging new technology.

  • Rapid Acting Antidepressants

    • 1st Edition
    • Volume 89
    • English
    The Advances in Pharmacology series presents a variety of chapters from the best authors in the field.

  • Reactive Oxygen Species (ROS), Nanoparticles, and Endoplasmic Reticulum (ER) Stress-Induced Cell Death Mechanisms

    • 1st Edition
    • Loutfy H. Madkour
    • English
    Reactive Oxygen Species (ROS), Nanoparticles, and Endoplasmic Reticulum (ER) Stress-Induced Cell Death Mechanisms presents the role of ROS‒mediated pathways cellular signaling stress, endoplasmic reticulum (ER) stress, oxidative stress, oxidative damage, nanomaterials, and the mechanisms by which metalloids and nanoparticles induce their toxic effects. The book covers the ecotoxicology of environmental heavy metal ions and free radicals on macromolecules cells organisms, heavy metals‒induced cell responses, oxidative stress, the source of oxidants, and the roles of ROS, oxidative stress and oxidative damage mechanisms. It also examines the nanotoxicity, cytotoxicity and genotoxicity mechanisms of nanomaterials and the effects of nanoparticle interactions. Antioxidant defense therapy and strategies for treatment round out the book, making it an ideal resource for researchers and professional scientists in toxicology, environmental chemistry, environmental science, nanomaterials and the pharmaceutical sciences.

  • Advances in Marine Biology

    • 1st Edition
    • Volume 86
    • English
    Advances in Marine Biology, Volume 86, the latest release in a series that has been providing in-depth and up-to-date reviews on all aspects of marine biology since 1963, updates on many topics that will appeal to postgraduates and researchers in marine biology, fisheries science, ecology, zoology and biological oceanography. Chapters in this new release include Marine Environmental DNA: Approaches, Applications, and Opportunities, and The Biology and Ecology of the Banana Prawns.

  • Receptor Tyrosine Kinases

    • 1st Edition
    • Volume 147
    • English
    Receptor Tyrosine Kinases, Volume 147 in the Advances in Cancer Research series, provides invaluable information on the exciting and fast-moving field of cancer research in the area of Receptor Tyrosine Kinases (RTKs) in the context of major basic science and translational advances, their importance in the development of a large number of anti-cancer drugs over the decades, and a peek into postulated advances in the coming decades for a number of RTK. Chapters in this new release are contributed by a group of International leading scientists who have a rich history in this field.

  • Rosenberg's Molecular and Genetic Basis of Neurological and Psychiatric Disease

    Volume 1
    • 6th Edition
    • Roger N. Rosenberg + 1 more
    • English
    Rosenberg’s Molecular and Genetic Basis of Neurologic and Psychiatric Disease, Sixth Edition: Volume One, provides a comprehensive introduction and reference to the foundations and key practical aspects relevant to neurologic and psychiatric disease. A favorite of over three generations of students, clinicians and scholars, this new edition retains and expands the informative, concise and critical tone of the first edition. This is an essential reference for general medical practitioners, neurologists, psychiatrists, geneticists, and related professionals, and for the neuroscience and neurology research community. The content covers all aspects essential to the practice of neurogenetics to inform clinical diagnosis, treatment and genetic counseling. Every chapter has been thoroughly revised or newly commissioned to reflect the latest scientific and medical advances by an international team of leading scientists and clinicians. The contents have been expanded to include disorders for which a genetic basis has been recently identified, together with abundant original illustrations that convey and clarify the key points of the text in an attractive, didactic format.

  • Meningiomas, Part II

    • 1st Edition
    • Volume 170
    • Michael W. McDermott
    • English
    Meningiomas, Volume 170, Part Two, discusses tumors that arise from the coverings of the brain and spinal cord. In this updated volume of the Handbook of Clinical Neurology, experts in the field - from basic scientists to skilled neurosurgeons, provide up-to-date synopses of each topic as it relates directly to this class of tumor. Surgical and radiation therapy, which remain the mainstays of treatment, are a major focus, but coverage also includes potential molecular avenues for the development of effective medical treatments. This book serves as a comprehensive review of the neurosurgical issues surrounding this extremely common brain tumor. Few procedures in surgery are more immediately formidable than an attack upon a large tumor of this type, hence the greatest challenge of treatment is the need to complete tumor removal without creating new neurologic deficit.

  • Maternal Effect Genes in Development

    • 1st Edition
    • Volume 140
    • English
    Current Topics in Developmental Biology series highlights new advances in the field, with this new volume presenting interesting chapters. Each chapter is written by one or more members of an international board of authors.

  • Rosenberg's Molecular and Genetic Basis of Neurological and Psychiatric Disease

    Volume 2
    • 6th Edition
    • Roger N. Rosenberg + 1 more
    • English
    Rosenberg’s Molecular and Genetic Basis of Neurologic and Psychiatric Disease, Sixth Edition: Volume Two provides a comprehensive introduction and reference to the foundations and practical aspects relevant to the majority of neurologic and psychiatric disease. This updated volume focuses on degenerative disorders, movement disorders, neuro-oncology, neurocutaneous disorders, epilepsy, white matter diseases, neuropathies and neuronopathies, muscle and neuromuscular junction disorders, stroke, psychiatric disease, and a neurologic gene map. A favorite of over three generations of students, clinicians and scholars, this new edition retains and expands on the informative, concise and critical tone of the first edition. This is an essential reference for general medical practitioners, neurologists, psychiatrists, geneticists, related professionals, and for the neuroscience and neurology research community at large. The content covers all aspects essential to the practice of neurogenetics to inform clinical diagnosis, treatment and genetic counseling.

  • Toxicology Cases for the Clinical and Forensic Laboratory

    • 1st Edition
    • Hema Ketha + 1 more
    • English
    Toxicology Cases for the Clinical and Forensic Laboratory brings together carefully selected case studies to teach important principles relating to drug and toxin exposures. Each case study includes contemporary clinical and forensic toxicologist studies that include a comprehensive analytical and clinical approach to patient management and address overdoses from designer drugs, to NSAIDS, to opioids, to stimulants. These cases present a comprehensive, analytical and clinical approach to managing a drug overdose. This is a must-have reference for clinical and forensic laboratory scientists, along with toxicology and pathology residents who need to know aspects of both.

  • Neuronal Chloride Transporters in Health and Disease

    • 1st Edition
    • Xin Tang
    • English
    In the past several years, there has been an exciting body of new research that links impairments in the expression or function of neuronal chloride transporters to a growing number of diseases spanning from autism to brain aging. This book introduces the core concepts and highlights the recent advances in understanding the physiology and pathophysiology of the KCC and NKCC families of neuronal chloride transporters. Neuronal chloride transporter biology is reviewed, including roles in setting the transmembrane chloride gradient and the chloride transport-independen... functions, such as regulating excitatory neurotransmission. Chapters are also dedicated to addressing the structure, post-translational modification, membrane trafficking, and protein interaction partners of neuronal chloride transporters, as well as the genetic and environmental factors that regulate their expression in neurons and the novel therapeutic approaches that target neuronal chloride transporters to treat neurological diseases. This new volume will provide readers with an up-to-date summary of the recent advances in neuronal chloride transporter research, with particular emphasis on some of the key emerging topics in the field.

  • Human Pluripotent Stem Cell Derived Organoid Models

    • 1st Edition
    • Volume 159
    • English
    Human Pluripotent Stem Cell Derived Organoid Models, Volume 159 highlights recent and emerging advances that describe organoid differentiation protocols for the different organ systems that implement organoids as tools to understand complexity and maturation, high content drug screening, disease modeling, development and evolution. Specific chapters in this new release include Pluripotent stem cell derived gastric organoids, Pluripotent stem cell derived esophageal organoids, Pluripotent stem cell derived small intestinal organoids, Pluripotent stem cell derived colonic organoids, Pluripotent stem cell intestinal organoids with an Enteric Nervous System, Pluripotent stem cell derived airway organoids, Pluripotent stem cell derived alveolar organoids, and much more.

  • Wheat - An Exceptional Crop

    Botanical Features, Chemistry, Utilization, Nutritional and Health Aspects
    • 1st Edition
    • Herbert Wieser + 2 more
    • English
    Wheat - An Exceptional Crop: Botanical Features, Chemistry, Utilization, Nutritional and Health Aspects presents the exceptional position of wheat among food crops. The book demonstrates the benefits and drawbacks of wheat from a wheat science, nutrition and technology perspective. Organized into 13 chapters, chapters 1 - 3 present a basic overview of wheat; chapters 4 - 6 explore the overall benefits of wheat for the general population, and chapters 7 - 13 assess wheat-related disorders that affect a small portion of the population. Wheat - An Exceptional Crop: Botanical Features, Chemistry, Utilization, Nutritional and Health Aspects is an exceptional reference for those working in and researching the fields of agronomy, food chemistry, food technology, nutrition, allergology and gastroenterology.

  • Transgenic Technology Based Value Addition in Plant Biotechnology

    • 1st Edition
    • Usha Kiran + 2 more
    • English
    Transgenic Technology Based Value Addition in Plant Biotechnology discusses the principles, methodology and applications of transgenic technologies. With step-by-step methods on genome editing techniques and a range of potential applications, from improving crop yield to increasing therapeutic efficacy, this book is a one-stop reference for plant gene editing technologies. It will be of particular interest to researchers interested in plant biotechnology and plant genetics, as well as agricultural scientists and those concerned with medicinal plants.

  • Artificial Intelligence in Cancer

    Diagnostic to Tailored Treatment
    • 1st Edition
    • Smaranda Belciug
    • English
    Artificial Intelligence in Cancer: Diagnostic to Tailored Treatment provides theoretical concepts and practical techniques of AI and its applications in cancer management, building a roadmap on how to use AI in cancer at different stages of healthcare. It discusses topics such as the impactful role of AI during diagnosis and how it can support clinicians to make better decisions, AI tools to help pathologists identify exact types of cancer, how AI supports tumor profiling and can assist surgeons, and the gains in precision for oncologists using AI tools. Additionally, it provides information on AI used for survival and remission/recurrence analysis. The book is a valuable source for bioinformaticians, cancer researchers, oncologists, clinicians and members of the biomedical field who want to understand the promising field of AI applications in cancer management.

  • Camptothecin and Camptothecin Producing Plants

    Botany, Chemistry, Anticancer Activity and Biotechnology
    • 1st Edition
    • T. Pullaiah + 4 more
    • English
    Camptothecin and Camptothecin Producing Plants: Botany, Chemistry, Anticancer Activity and Biotechnology provides updated information on camptothecin yielding plants, chemical diversity of camptothecin, extraction and exploitation methods, biosynthesis, biotechnological production and enhancement for drug delivery, and the pharmacological properties of the drugs. The book focuses on camptothecin anticancer properties based on recent developments of biotechnology. Topics emphasize anticancer activities, biosynthesis, potent derivatives currently undergoing experimental phases, and biotechnological methods to enhance the production. This book is a valuable source for cancer researchers, oncologists, biotechnologists, pharmacologists and members of the biomedical field who are interested in camptothecin and its applicability in cancer treatment.

  • Autophagy in Health and Disease

    • 1st Edition
    • Volume 172
    • English
    Autophagy in Health and Disease, Volume 175, presents the latest insights from renowned experts in the field who discuss the key role of autophagic responses in the preservation of cellular and organismal homeostasis and how defects in the molecular apparatus for autophagy drive or accompany disease. Specific chapters in this new release include Crosstalk between autophagy and cell death signaling: mechanisms and therapeutic relevance, C. elegans to model autophagy-related human disorders, Autophagy in Kidney Disease: advances and therapeutic potential, Autophagy in Chronic Lung Disease, Autophagy in motoneuronal disorders, Strategies employed by viruses to manipulate autophagy, and much more.

  • Advances in Clinical Chemistry

    • 1st Edition
    • Volume 98
    • English
    Advances in Clinical Chemistry, Volume 98, the latest installment in this internationally acclaimed series, contains chapters authored by world-renowned clinical laboratory scientists, physicians and research scientists. The serial discusses the latest and most up-to-date technologies related to the field of clinical chemistry. It is the benchmark publication for novel analytical approaches in the clinical laboratory.

  • Ureteroceles

    Contemporary Diagnosis and Management
    • 1st Edition
    • Michael P. Leonard + 1 more
    • English
    Ureteroceles: Contemporary Diagnosis and Management provides an evidence-based review of current diagnosis and management options for patients with ureteroceles. With the advent of antenatal ultrasound screening, ureteroceles are presenting earlier, often in asymptomatic patients, proving the need for active surveillance. With no fixed protocols and guidelines currently in the field, this important reference brings together recent techniques, such as in utero puncture, endoscopic laser fenestration, and laparoscopic clipping of the upper moiety ureter. Case studies illustrate various diagnostic and management options. This important reference provides all the necessary resources for ureterocele diagnosis and management needed by urology researchers, pediatric urologists, and general surgeons.

  • Encyclopedia of Bone Biology

    • 1st Edition
    • Mone Zaidi
    • English
    Encyclopedia of Bone Biology, Three Volume Set covers hot topics from within the rapidly expanding field of bone biology and skeletal research, enabling a complete understanding of both bone physiology and its relation to other organs and pathophysiology. This encyclopedia will serve as a vital resource for those involved in bone research, research in other fields that cross link with bone, such as metabolism and immunology, and physicians who treat bone diseases. Each article provides a comprehensive overview of the selected topic to inform a broad spectrum of readers from advanced undergraduate students to research professionals. Chapters also explore the latest advances and hot topics that have emerged in recent years, including the Hematopoietic Niche and Nuclear Receptors. In the electronic edition, each chapter will include hyperlinked references and further readings as well as cross-references to related articles.

  • Chemical Analysis of Food

    Techniques and Applications
    • 2nd Edition
    • Yolanda Pico
    • English
    Chemical Analysis of Food: Techniques and Applications, Second Edition, reviews the latest technologies and challenges in all stages of food analysis, from selecting the right approach, how to perform analytic procedures, and how to measure and report the results. The book is structured in two parts: the first describes the role of the latest developments in analytical and bio-analytical techniques, with the second reviewing innovative applications and issues in food analysis. The techniques discussed range from the non-invasive and non-destructive, such as infrared spectroscopy and ultrasound, to newly emerging areas, such as nanotechnology, biosensors and electronic noses and tongues. This thoroughly updated edition includes new chapters on ambient mass spectrometry, imaging techniques, omics approaches in food analysis, natural toxins analysis, food contact materials, nanomaterials and organic foods. All chapters are updated or rewritten to bring the content completely up-to-date.

  • Building the Future of Food Safety Technology

    Blockchain and Beyond
    • 1st Edition
    • Darin Detwiler
    • English
    Building the Future of Food Safety Technology: Blockchain and Beyond focuses on evaluating, developing, testing and predicting Blockchain’s impact on the food industry, the types of regulatory compliance needed, and other topics important pertaining to consumers. Blockchain is a technology that can be used to record transactions from multiple entities across a complex network. A record on a blockchain cannot be altered retroactively without the alteration of all preceding blocks and the consensus of the network. Blockchain is often associated with cryptocurrency, but it is being looked at more and more as a solution to food-supply problems.

  • Chemical Tools for Imaging, Manipulating, and Tracking Biological Systems: Diverse Methods Based on Optical Imaging and Fluorescence

    • 1st Edition
    • Volume 640
    • English
    This new volume of Methods in Enzymology continues the legacy of this premier serial with quality chapters authored by leaders in the field.

  • Placebo Effects in Neurologic Disease

    • 1st Edition
    • Volume 153
    • English
    Placebo Effects in Neurologic Disease, Volume 153, the latest release in the International Review of Neurobiology series, highlights new advances in the field, with this new volume presenting interesting chapters on Background and Methods in Placebo, Better than Nothing: A Historical Account of Placebos and Placebo Effects from Modern to Contemporary Medicine, Determinants of PE, Strategies for Minimizing PE in Research, Maximizing placebo response in the clinic, Statistical methods for handling PE, Nocebo and Lessebo effects, Ethics of deception, Pain, Parkinson's Disease, Cognitive impairment, Epilepsy, and much more.

  • Meningiomas, Part I

    • 1st Edition
    • Volume 169
    • Michael W. McDermott
    • English
    Meningiomas, Volume 169, Part One, serves as a comprehensive review of the neurosurgical issues surrounding this extremely common brain tumor. Few procedures in surgery are more immediately formidable than an attack upon a large tumor of this type. In this volume of the Handbook of Clinical Neurology, experts in the field - from basic scientists to skilled neurosurgeons - have provided up-to-date synopses of each topic as it relates to this class of tumor. Surgical and radiation therapy, which remain the mainstays of treatment, are a major focus, but coverage also includes potential molecular avenues for the development of effective medical treatments.

  • National Institute of Parasitic Diseases, China

    70 Years and Beyond
    • 1st Edition
    • Volume 110
    • English
    National Institute of Parasitic Diseases, China: 70 Years and Beyond, Volume 110 covers the major achievements gained in the research and control of parasitic diseases in China, e.g. schistosomiasis, malaria, lymphatic filariasis, echinococcosis, visceral leishmaniasis, soil-transmitted helminthiasis, foodborne clonorchiasis, angiostrongyliasis, taeniasis and cysticercosis, etc. The book introduces approaches that can be developed with big data analytic tools, how to use surveillance-respons... systems at national and regional levels, and tactics to promote the national parasitic resources center to support various research and control activities. Finally, a chapter on the roadmap for parasitic diseases control in China from 2020 to 2030 is presented.

  • Handbook of Food Nanotechnology

    Applications and Approaches
    • 1st Edition
    • Seid Mahdi Jafari
    • English
    Food Nanotechnology: Applications and Approaches is the definitive guide on all aspects of nano-sized ingredients and devices for the food sector. The book brings science and applications together on the nano-scale into nano-structured food materials, with an emphasis on their production, processing, engineering, characterization, and applications of food materials containing true nano-sized dimensions or nano-structures that enable novel/enhanced properties or functions. All chapters emphasize original results relating to experimental, theoretical, computational, and/or applications of nano-materials in food. Topics such as the application of nanotechnology in food processing operations, functional ingredients, quality control, nutraceutical delivery, and packaging of food products are very attractive and beneficial to both academics and practitioners. Finally, the safety of applying nano ingredients and nano devices is covered.

  • Avances en endocrinología quirúrgica

    • 1st Edition
    • Alexander L. Shifrin
    • Spanish

  • Essential and Toxic Trace Elements and Vitamins in Human Health

    • 1st Edition
    • George J. Brewer + 1 more
    • English
    Essential and Toxic Trace Elements and Vitamins in Human Health is a comprehensive guide to the wide variety of micronutrients that affect human health, including fat-soluble and water-soluble vitamins that support diverse biochemical functions, trace elements with established and suggested links to health maintenance, and elements with known human toxicity such as arsenic, cadmium, and lead. An essential reference text for nutritionists working in academia and functional food and supplement industries, dieticians, and clinicians, Essential and Toxic Trace Elements and Vitamins in Human Health provides an in-depth look at toxic trace elements and essential vitamins and minerals and their direct influence on the body’s overall health with expert research from renowned scientists.

  • Aquaculture Health Management

    Design and Operation Approaches
    • 1st Edition
    • Frederick S.B. Kibenge + 1 more
    • English
    Aquaculture Health Management: Design and Operation Approaches is an essential reference for the diverse aquaculture community. With the steadily increasing importance of healthy fish production and the expansion of the animal aquaculture industry to new geographic areas, new microbial and parasitic species with pathogenic potential continue to emerge. The book covers the broad spectrum of fish and shellfish health, the functional roles of pathogen emergence, and the impacts of nutrition and preventative medicine such as pre- and probiotics, as well as chemical treatments, relevant legislation and more. This reference takes a comprehensive approach to understanding overall fish health management, making it valuable to aquaculturists, practitioners in aquatic animal health, veterinarians and all those in industry, government or academia who are interested in aquaculture and fisheries and their sustainable futures.

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