Hormones and Synapse
- 1st Edition, Volume 114 - July 26, 2020
- Imprint: Academic Press
- Editor: Gerald Litwack
- Language: English
- Hardback ISBN:9 7 8 - 0 - 1 2 - 8 2 2 0 2 5 - 2
- eBook ISBN:9 7 8 - 0 - 1 2 - 8 2 2 0 2 6 - 9
Hormones and Synapse, Volume 114 in the Vitamins and Hormones series, highlights advances in the field, with this new volume presenting timely topics, including how growth ho… Read more
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Request a sales quoteHormones and Synapse, Volume 114 in the Vitamins and Hormones series, highlights advances in the field, with this new volume presenting timely topics, including how growth hormone promotes synaptogenesis, sex hormones and proteins involved in brain plasticity, corticotropin releasing factor modulates excitatory synaptic transmission, bisphenol a and memory: a role for dendritic spines, brain insulin resistance impairs hippocampal synaptic plasticity, estradiol induces synaptic rearrangements, stress and remodeling of hippocampal spine synapses, neurotrophin-3 modulates synaptic transmission, nongenomic neurosteroid modulation of hippocampal dendritic spines, neural sex steroids and hippocampal synaptic plasticity, origin of chemical synapses, neural sex steroids and hippocampal synaptic plasticity, and much more.
- Provides the authority and expertise of leading contributors from an international board of authors
- Presents the latest release in the Vitamins and Hormones series
- Includes the latest information on Hormones and Synapse
Undergraduates, graduates, academics and researchers in the field of vitamins and hormones
- Cover image
- Title page
- Table of Contents
- Copyright
- Former Editors
- Contributors
- Preface
- Chapter One: Evolutionary origins of chemical synapses
- Abstract
- 1: Introduction
- 2: A brief prehistory of the chemical synapse
- 3: Modes of neuronal integration: Electrical and chemical synaptic transmission
- 4: Formation of chemical synapses in action
- 5: Secretion and sensing elements at chemical synapses
- 6: Summary and outstanding questions
- Acknowledgments
- Chapter Two: Ultrastructural and molecular features of excitatory and glutamatergic synapses. The auditory nerve synapses
- Abstract
- 1: Introduction
- 2: The history of synapse ultrastructure
- 3: General features of the ultrastructure and molecular components of synapses
- 4: Key ultrastructural features of the glutamatergic synapses PSD that correlate to synaptic function
- 5: Molecular structure of auditory nerve synapses
- 6: Conclusions
- Acknowledgments
- Chapter Three: Corticotropin releasing factor modulates excitatory synaptic transmission
- Abstract
- 1: Introduction
- 2: Prefrontal cortex
- 3: Amygdala
- 4: Hippocampus
- 5: Cerebellum
- 6: Locus coeruleus
- 7: Raphe nuclei
- 8: Conclusions
- Chapter Four: Neurotrophin-3 modulates synaptic transmission
- Abstract
- 1: Neurotrophins
- 2: NT-3
- 3: NT-3 receptors
- 4: NT-3 modulation of synaptic transmission
- 5: Mechanisms of synaptic modulation
- 6: Conclusions and open questions
- Acknowledgments
- Chapter Five: Growth hormone (GH) and synaptogenesis
- Abstract
- 1: Introduction
- 2: Growth hormone (GH) and GH receptor (GHR)
- 3: Growth hormone and synaptogenesis during development
- 4: Effects of GH in axonal growth and synaptic function
- 5: Effects of GH in synaptic function during neuroprotection and neuroregeneration
- 6: Conclusion
- Acknowledgments
- Chapter Six: Neural sex steroids and hippocampal synaptic plasticity
- Abstract
- 1: Synthesis of sex steroids in the hippocampus
- 2: How to assess synaptic plasticity in the hippocampus
- 3: Paracrine mode of action of sex neurosteroids
- 4: Sex-specific responsiveness of hippocampal neurons to sex neurosteroids
- 5: Sex-specific differentiation of hippocampal neurons
- 6: Conclusions and future directions
- Acknowledgments
- Chapter Seven: Sex hormones and proteins involved in brain plasticity
- Abstract
- 1: Brain plasticity
- 2: Sex hormones and brain
- 3: Sex hormones and brain plasticity
- 4: Conclusions and future directions
- Chapter Eight: Synaptic effects of estrogen
- Abstract
- 1: Introduction
- 2: Physiological and pathophysiological roles of estrogen-induced synaptic plasticity
- 3: Methodological considerations
- 4: Effects of estradiol on spine and spine synapse density
- 5: Underlying mechanisms
- 6: Concluding remarks
- Chapter Nine: Estrogen receptor signaling through metabotropic glutamate receptors
- Abstract
- 1: Introduction
- 2: Metabotropic glutamate receptors
- 3: Estrogen receptor/mGluR interactions
- 4: mGluR interactions with other hormone receptors
- 5: Conclusions and future directions
- Chapter Ten: Estradiol induces synaptic rearrangements
- Abstract
- 1: Introduction
- 2: Estradiol receptors
- 3: Estrogens and spine density
- 4: Estrogens and “Two-step Wiring Plasticity”
- 5: Family of synaptic modulators
- 6: Conclusion
- Acknowledgment
- Chapter Eleven: Stress and remodeling of hippocampal spine synapses
- Abstract
- 1: Stress-induced loss of hippocampal spine synapses
- 2: Mechanisms of synapse loss
- 3: Synaptogenic hypothesis of major depressive disorder
- 4: Relevance of prevention in antidepressant therapy
- 5: Importance of electron microscopy
- Acknowledgments
- Chapter Twelve: Brain insulin resistance impairs hippocampal plasticity
- Abstract
- 1: Introduction
- 2: Insulin and brain
- 3: Effects of brain insulin resistance
- 4: Crosstalk between brain insulin resistance and Alzheimer's disease
- 5: Conclusions
- Acknowledgments
- Conflict of interests
- Chapter Thirteen: A potential role for dendritic spines in bisphenol-A induced memory impairments during adolescence and adulthood
- Abstract
- 1: Bisphenol-A (BPA): An endocrine disruptor
- 2: Effects of BPA on dendritic spine plasticity
- 3: Conclusions and future directions
- Edition: 1
- Volume: 114
- Published: July 26, 2020
- No. of pages (Hardback): 346
- No. of pages (eBook): 346
- Imprint: Academic Press
- Language: English
- Hardback ISBN: 9780128220252
- eBook ISBN: 9780128220269
GL
Gerald Litwack
Dr. Litwack has authored 3 textbooks on biochemistry and hormones (one with John Wiley & Sons and 2 with Academic Press/Elsevier) and he has edited more than 70 volumes in the Vitamins & Hormones series (Academic Press/Elsevier); he has edited 14 volumes entitled Biochemical Actions of Hormones (Academica Press); He has edited (with David Kritchevsky) Actions of Hormones on Molecular Processes (Academic Press)
Affiliations and expertise
Emeritus Founding Chair and Professor, Geisinger Commonwealth School of Medicine, United States
Emeritus Professor, Rutgers University, United StatesRead Hormones and Synapse on ScienceDirect