Skip to main content
Elsevier
View Cart

Diagnosis and Management in Dementia

The Neuroscience of Dementia, Volume 1

  • 1st Edition - August 11, 2020
  • Latest edition
  • Editors: Colin R. Martin, Victor R. Preedy
  • Language: English

Diagnosis and Management in Dementia: The Neuroscience of Dementia, Volume 1 consolidates different fields of dementia into a single book, covering a range of subjects, includ… Read more

World Book Day celebration

Where learning shapes lives

Up to 25% off trusted resources that support research, study, and discovery.

Explore resources

Description

Diagnosis and Management in Dementia: The Neuroscience of Dementia, Volume 1 consolidates different fields of dementia into a single book, covering a range of subjects, including Alzheimer’s disease, Lewy body dementia, mixed dementia, vascular dementia, physical activity, risk factors, mortality, biomarkers, SPECT, CT, MRI, questionnaires, nutrition, sleep, delirium, hearing loss, agitation, aggression, delusions, anxiety, depression, hallucinations, psychosis, senile plaques, tau and amyloid-beta, neuroinflammation, molecular biology, and more. With an impact on millions globally, and billions of research dollars being invested in dementia research, this book will stimulate research in the area and inform researchers.

Key features

  • Offers comprehensive coverage of a broad range of topics related to dementia
  • Serves as a foundational collection for neuroscientists and neurologists on the biology of dementia and brain dysfunction
  • Contains in each chapter an abstract, key facts, mini dictionary of terms, and summary points to aid in understanding
  • Provides unique sections on specific subareas, intellectual components, and knowledge-based niches that will help readers navigate key areas for research and further clinical recommendations
  • Features preclinical and clinical studies to help researchers map out key areas for research and further clinical recommendations
  • Serves as a "one-stop" source for everything you need to know about dementia

Readership

Neuroscientists/neurologists, psychologists, health scientists, public health workers, research scientists, pharmacologists, and physicians. It is suitable for graduate/postgraduate students, lecturers, and professors.

Table of contents

Part I: Dementia: introductory chapters and setting the scene

1. Mixed dementia: a neuropathological overviewJacques De Reuck

2. Vascular dementia: an overviewVirginia Cipollini, Fernanda Troili and Franco Giubilei

3. Small vessel disease and dementiaFrancesco Arba and Valentina Rinnoci

4. Linking amyotrophic lateral sclerosis and frontotemporal dementiaCouratier Philippe

5. Mortality in dementia: linking in the role of deliriumFlavia Barreto Garcez and Thiago Junqueira Avelino-Silva

6. Midlife diabetes and the risk of dementia: understanding the linkAdam H. Dyer and Sean P. Kennelly

7. Gait and dementiaOshadi Jayakody and Michele L. Callisaya

8. The role of blood pressure and hypertension in dementiaKeenan A. Walker and Rebecca F. Gottesman

9. Genetics of dementia: a focus on Alzheimer’s diseaseFrancesca Fernandez and Jessica L. Andrews

10. Clinical and pathological phenotypes in dementia: a focus on autosomal dominant frontotemporal dementiaInnocenzo Rainero, Alessandro Vacca and Elisa Rubino

11. Environmental and genetic risk factors for dementiaVanesa Bellou, Lazaros Belbasis and Evangelos Evangelou

12. Lipids, brain ageing, dementia, and lipidomicsAnne Poljak, Braidy Nady, Wong Matthew Wai Kin, Yue Liu, Mahboobeh Housseini and Sachdev Perminder Singh

13. The 5xFAD mouse model of Alzheimer’s disease Caroline Ismeurt, Patrizia Giannoni and Sylvie Claeysen

Part II: Biomarkers, psychometric instruments and diagnosis

14. Use of cerebrospinal fluid in diagnosis of dementiaAngelo Nuti, Cecilia Carlesi, Elena Caldarazzo Ienco, Gabriele Cipriani and Paolo Del Dotto

15. Salivary biomarkers in Alzheimer’s disease Jessica L. Andrews and Francesca Fernandez

16. Diacylglycerols: biomarkers of a sustained immune response in proteinopathiesPaul L. Wood and Randall J. Woltjer

17. Butyrylcholinesterase as a biomarker in Alzheimer’s diseaseDrew R. DeBay and Sultan Darvesh

18. Blood brain-derived neurotrophic factor as a biomarker of Alzheimer’s diseaseMarta Balietti

19. The neuroscience of dementia: diagnosis and management methods of amyloid positron emission tomography imaging and its application to the Alzheimer’s disease spectrumShizuo Hatashita

20. Diffusion-weighted imaging (DWI) tractography and Alzheimer’s diseaseNicola Amoroso

21. Transcranial magnetic stimulation in the cortical exploration of dementiaThanuja Dharmadasa, William Huynh and Matthew C. Kiernan

22. The role of retinal imaging in Alzheimer’s diseaseVictor T.T. Chan and Carol Y. Cheung

23. Prediction of Alzheimer’s diseaseAthanasios Alexiou, Stylianos Chatzichronis and Ghulam Md Ashraf

24. Addenbrooke’s Cognitive ExaminationJordi A. Matias-Guiu

25. Beyond the cutoffs: a Bayesian approach to the use of the Montreal Cognitive Assessment as a screening tool for mild cognitive impairment and dementiaAndrea Bosco, Alessandro O. Caffo, Giuseppina Spano and Antonella Lopez

26. Utility of ALBA screening instrument: the prodromal phase of dementia with Lewy bodiesWaleska Berríos and Angel Golimstok

27. The quick mild cognitive impairment screen and applications to dementia Ron an O’Caoimh, D. William Molloy and Roger Clarnette

28. The usefulness of evaluating performance of activities of daily living in the diagnosis of mild cognitive disordersPatricia De Vriendt, Elise Cornelis and Ellen Gorus

Part III: Pharmacological treatments for dementia

29. Cholinesterase inhibitors in dementias: an overviewPatrizia Mecocci, Lucia Paolacci and Virginia Boccardi

30. Choline-containing phospholipids and treatment of adult-onset dementia disordersFrancesco Amenta, Gopi Battineni, Enea Traini and Graziano Pallotta

31. Donepezil in the treatment of Alzheimer’s diseaseGabriella Marucci, Michele Moruzzi and Francesco Amenta

32. Memantine and Alzheimer’s disease: a comprehensive reviewSergio del Río-Sancho

33. A new neuroprotective strategy for the drug therapy of Parkinson’s disease: the Ca2þ/cAMP signaling as therapeutic targetAfonso Caricati-Neto, Fulvio Alexandre Scorza and Leandro Bueno Bergantin

34. Pitfalls and possible solutions for research and development of dementia therapiesThomas Muller €

35. All-trans retinoic acid in Alzheimer’s diseaseSiamak Beheshti

36. Dementia and usage of N-methyl-D-aspartate receptor antagonistsB.E. Glynn-Servedio

37. Swallowing impairment in Parkinson’s diseaseMaira Rozenfeld Olchik, Marina Padovani and Annelise Ayres

38. Linking astrocytes’ exosomes to Alzheimer pathogenesis and therapyAnna M. Chiarini, Ubaldo Armato, Claudio Eccher and Ilaria Dal Pr

39. Changing fate: therapeutic mechanisms focused on the switch of amyloid precursor protein processingSven Reinhardt and Kristina Endres

40. Acetylcholinesterase inhibitory agents in plants and their application to dementia: Alzheimer’s diseaseWillian Orlando Castillo-Ordonez and Nohelia Cajas-Salazar

41. Removal of blood amyloid-b as an effective and safe therapeutic strategyNobuya Kitaguchi, Kazunori Kawaguchi and Kazuyoshi Sakai

Part IV: Non-pharmacological treatments and procedures

42. Caring for people with dementia in the acute hospitalRobert Briggs, Paul Claffey and Sean P. Kennelly

43. Environmental enrichment as a preventative and therapeutic approach to Alzheimer’s diseaseKimberley E. Stuart, Anna E. King and James C. Vickers

44. Music therapy in dementia: the effects of music therapy and other musical interventions on behavior, emotion, and cognitionAlfredo Raglio and Lapo Attardo

45. Exploitation of aromatherapy in dementiadimpact on pain and neuropsychiatric symptomsDamiana Scuteri, Laura Rombol

46. Dancing in dementiaLee-Fay Low, Helen Parker, Kathryn Dovey and Alycia Fong Yan

47. Hypoxicehyperoxic conditioning and dementiaRobert T. Mallet, Johannes Burtscher, Eugenia B. Manukhina, H. Fred Downey, Oleg S. Glazachev, Tatiana V. Serebrovskaya and Martin Burtscher

48. Linking amyloid and depression in the development of Alzheimer’s disease: effects of neuromodulatory interventions by brain stimulationAkihiko Nunomura, Toshio Tamaoki, Kenji Tagai, Shinsuke Kito, Shunichiro Shinagawa and Masahiro Shigeta

49. Regional and local dementia care networksFranziska Laporte Uribe, Karin Wolf-Ostermann, Jochen Rene Thyrian and Bernhard Holle

50. Cognitive behavioral therapy use in Alzheimer’s disease: mitigating risks associated with the olfactory brainLarry D. Reid, Dylan Z. Taylor and Alicia A. Walf

51. Maximizing cognition in mild cognitive impairment and early stage dementiaBridget Regan, Yvonne Wells and Paul O’Halloran

52. Exercise, cognitive creativity, and dementiaEmily Frith and Paul D. Loprinzi

53. Person-centered communication among formal caregivers of persons with dementiaMarie Y. Savundranayagam and Pabiththa Kamalraj

Index

Product details

  • Edition: 1
  • Latest edition
  • Published: August 11, 2020
  • Language: English

About the editors

CM

Colin R. Martin

Colin R. Martin RN, BSc, MSc, PhD, MBA, YCAP, FHEA, C.Psychol, AFBPsS, C.Sci is Professor of Clinical Psychobiology and Applied Psychoneuroimmunology and Clinical Director of the Institute of Health and Wellbeing at the University of Suffolk, UK. He is a Chartered Health Psychologist and a Chartered Scientist. He also trained in analytical biochemistry, this aspect reflecting the psychobiological focus of much of his research within mental health. He has published or has in press well over 300 research papers and book chapters. He is a keen book author and editor having written and/or edited more than 50 books. These outputs include the prophetic insight into the treatment of neurological disease, Handbook of Behavior, Food and Nutrition (2011), Nanomedicine and the Nervous System (2012), Oxidative Stress and Dietary Antioxidants in Neurological Disease (2020), Zika Virus Impact, Diagnosis, Control and Models (2021), Factors Affecting Neurodevelopment: Genetics, Neurology, Behavior and Diet (2021), Diagnosis and Treatment of Spinal Cord Injury (2022), The Neurobiology, Physiology, and Psychology of Pain (2022) and The Handbook of Lifespan Cognitive Behavioral Therapy: Childhood, Adolescence, Pregnancy, Adulthood, and Aging (2023). Professor Martin is particularly interested in all aspects of the relationship between underlying physiological substrates and behavior, particularly in how these relationships manifest in both acute and chronic psychiatric disorder. He has published original research germane to significant mental health disorders including the areas of schizophrenia, anxiety, depression, self-esteem, alcohol and drug dependency, high secure forensic mental health and personality disorder. He has a keen interest in the impact of postviral illness and is actively involved in clinical research post-Covid pandemic and in particular, the impact of Long Covid on psychological, neurological, physiological and social functioning. He is involved in collaborative International research with many European and Non-European countries.
Affiliations and expertise
Visiting Professor of Perinatal Wellbeing, Institute for Health and Wellbeing, University of Suffolk, Ipswich, UK

VP

Victor R. Preedy

Victor R. Preedy BSc, PhD, DSc, FRSB, FRSPH, FRSC, FRCPath graduated with an Honours Degree in Biology and Physiology with Pharmacology. After gaining his University of London PhD, he received his Membership of the Royal College of Pathologists. He was later awarded his second doctorate (DSc), for his contribution to protein metabolism in health and disease. He is Professor of Clinical Biochemistry (Hon) at King’s College Hospital and Emeritus Professor of Nutritional Biochemistry at King’s College London. He has Honorary Professorships at the University of Hull, and the University of Suffolk. Professor Preedy was the Founding Director and then long-term Director of the Genomics Centre at King’s College London from 2006 to 2020. Professor Preedy has been awarded fellowships of the Royal Society of Biology, the Royal College of Pathologists, the Royal Society for the Promotion of Health, the Royal Institute of Public Health, the Royal Society for Public Health, the Royal Society of Chemistry and the Royal Society of Medicine. He carried out research when attached to the National Heart Hospital (part of Imperial College London), The School of Pharmacy (now part of University College London) and the MRC Centre at Northwick Park Hospital. He has collaborated with international research groups in Finland, Japan, Australia, USA, and Germany. To his credit, Professor Preedy has published over 750 articles, which includes peer-reviewed manuscripts based on original research, abstracts and symposium presentations, reviews and edited books.
Affiliations and expertise
Professor, Department of Clinical Biochemistry, King’s College Hospital, London, UK; Emeritus Professor, Faculty of Life Sciences and Medicine, King’s College London, UK; Visiting Professor, University of Hull, UK

View book on ScienceDirect

Read Diagnosis and Management in Dementia on ScienceDirect