Our Wired Nerves
The Human Nerve Connectome
- 1st Edition - July 23, 2020
- Imprint: Academic Press
- Author: Douglas W Zochodne
- Language: English
- Paperback ISBN:9 7 8 - 0 - 1 2 - 8 2 1 4 8 7 - 9
- eBook ISBN:9 7 8 - 0 - 1 2 - 8 2 1 4 8 8 - 6
The nervous system is a complex, sophisticated system that regulates and coordinates body activities. It is made up of two major divisions: the central nervous system consisting of… Read more
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Request a sales quoteThe nervous system is a complex, sophisticated system that regulates and coordinates body activities. It is made up of two major divisions: the central nervous system consisting of the brain and spinal cord and the peripheral nervous system. This consists of all other neural elements, including the peripheral nerves and the autonomic nerves. Peripheral nerves are the essential connections between the brain and spinal cord and the body. Without nerves there is no movement or sensation. Our Wired Nerves: The Human Nerve Connectome, reviews the essential anatomy and physiology of the peripheral nerve. It introduces the reader to what neuropathies are, how pain arises from damaged nerves and how nerves might be regenerated, including new and exciting ideas over how to coax their regrowth. Written by Dr. Douglas Zochodne leading expert in the field, and first book to focus on the Peripheral nerves it will surely be an essential reference for researchers and clinicians alike.
- Discusses the barriers to nerve regrowth and new strategies to reverse them
- Reviews of disorders of the peripheral nerves
- Exams reasons for nerve injuries
- Reviews recent discoveries in nerve research
Students studying peripheral neuropathy field, neuroscience, and central nervous system. Clinicians treating patients with peripheral neuropathies
- Cover image
- Title page
- Table of Contents
- Copyright
- Author’s biography
- Preface
- Acknowledgments
- Abbreviations
- Introduction
- The body brain connection: A fully infiltrated body
- References
- Chapter 1: Elegant wiring: Structural beauty of the peripheral nervous system
- Abstract
- How are nerves structured?
- Nodes of excitability
- Sockets and interfaces: Nerve terminals
- References
- Chapter 2: Constantly think physiology: Structure meets function
- Abstract
- Remarkable conduits
- Action potentials: How the connectome is activated
- Action potentials out of control: Fasciculations, pain and other troubles
- Other things move within axons: Axoplasmic transport
- Do I have good reflexes—What are these?
- Nerves and muscles: The motor units
- Movement and Walking: putting your nerves out there
- Exquisite sensation
- Considering taste
- Sensory nerves, not just bystanders
- References
- Chapter 3: Irreversible events: How nerves are injured
- Abstract
- Why don’t we hear about these?
- What kinds of nerve injuries are there?
- If a nerve injury occurs, this is the type you might prefer
- Nerve damage that does not recover well
- Nerve damage that rarely recovers
- References
- Chapter 4: Are there nerves? How to test the peripheral nervous system
- Abstract
- The neurological examination: Honed classicism
- Diagnostic shocks and needles
- Imaging portions of nerves
- Chop it out: Biopsy of a nerve
- Detective work: What blood can tell us about nerves
- References
- Chapter 5: What are neuropathies?
- Abstract
- Mononeuropathies in humans: Intense pain and disability
- What are polyneuropathies: Curious, common and various?
- References
- Chapter 6: Locked in
- Abstract
- References
- Chapter 7: The disrupted connectome and pain
- Abstract
- References
- Chapter 8: Hope and change: Regrowth of nerves
- Abstract
- The adult nervous system is remodeling
- First clean the mess
- Take my hand: Growth cones that lead the axon
- What do snake venom and mouse salivation have to do with nerves?
- Playing with fire: Inflammation and damaged nerves
- Neuron HQ central and damaged axons
- Are there new neurons?
- What is collateral sprouting?
- Persuading neurons not to be boring
- Behaving like a baby: Developmental molecules for regeneration
- Making new nerves: Summarizing the steps
- References
- Chapter 9: Clinics and biology: Nerve heroes and the Peripheral Nerve Society
- Abstract
- References
- Conclusions
- References
- Index
- Edition: 1
- Published: July 23, 2020
- No. of pages (Paperback): 270
- No. of pages (eBook): 270
- Imprint: Academic Press
- Language: English
- Paperback ISBN: 9780128214879
- eBook ISBN: 9780128214886
DW
Douglas W Zochodne
Dr. Douglas Zochodne is a Neurologist and Neuroscientist, Director of the Neuroscience and Mental Health Institute, and Past Divisional Director of Neurology at the University of Alberta (UofA). Dr. Zochodne’s career has included faculty positions at Queen’s University, Canada, the University of Calgary and more recently the University of Alberta. Dr. Zochodne’s roles have included Editor-in-Chief of the Canadian Journal of Neurological Sciences, and President of the Peripheral Nerve Society. He is a Fellow of the Canadian Academy of Health Sciences and his book “Our Wired Nerves: The Human Nerve Connectome” was published in 2020. He has devoted his career toward understanding the biology and diseases of the peripheral nervous system.
Affiliations and expertise
Neurologist and Neuroscientist, Director of the Neuroscience and Mental Health Institute, University of Alberta, Alberta, CanadaRead Our Wired Nerves on ScienceDirect