Skip to main content
Elsevier

Books in Life sciences

  • A Theory of the Formation of Animals

    • 1st Edition
    • W. T. Hillier
    • English
    A Theory of the Formation of Animals describes the details of formation of man, the structure, development, and physiology. This book is composed of seven chapters and begins with an introduction to a theory of animal formation, namely, the theory of dual constitution. This theory hypothesize that if new types of animal arise through the fusion of two animals of dissimilar kind, then one ought to find among the members of the animal kingdom some forms which might be called Type Animals. Two of these type animals are considered, the archi-annelid Polygordius and the herring (Clupea harengus). The final chapters describe the theoretical aspects of their skeleton and bones. This book is of value to zoologists, theorists, and researchers in the allied fields.

  • Clinical Methods of Neuro-Ophthalmologic Examination

    • 1st Edition
    • Alfred Kestenbaum
    • English
    Clinical Methods of Neuro-Ophthalmologic Examination presents the clinical methods of ophthalmologic examination that may be helpful in neurologic differential diagnosis. Neuro-ophthalmologic examination has developed in two directions: the more precise methods and the unrefined yet fairly exact methods, such as diagnostic measurement by means of a simple ruler. This book is based on lectures delivered by the author to neurologists and ophthalmologists. This book is composed of 13 chapters and begins with a presentation of anatomic details that are important for the understanding of the various signs and symptoms. The next chapters examine the development of simple perimetry into quantitative perimetry and angio-scotometry, as well as the pathology of the optic nerve. Considerable chapters are devoted to intensive discussions on group of diseases that affect in a parallel way the central nervous system and the eye, such as chiasmal and retrochiasmal lesions, nystagmus, symmetrical eye movement disturbance, palpebral fissure, hemicrania. The final chapter outlines a routine neuro-ophthalmologic... examination. This book is directed toward neurologists and ophthalmologists.

  • Current Topics in Comparative Pathobiology

    Volume 1
    • 1st Edition
    • Thomas C. Cheng
    • English
    Current Topics in Comparative Pathobiology, Volume 1 covers topics on the pathobiology of animals, invertebrate and vertebrate. The book discusses diseases of the insect integument; neoplasia in fish; and the status of paralytic shellfish poisoning. The text also describes small, free-living amebas with regard to its cultivation, quantitation, identification, classification, pathogenesis, and resistance. Pathobiologists, cellular biologists, parasitologists, and microbiologists will find the book invaluable.

  • Marihuana Biological Effects

    Analysis, Metabolism, Cellular Responses, Reproduction and Brain
    • 1st Edition
    • Gabriel G. Nahas + 1 more
    • English
    Marihuana Biological Effects: Analysis, Metabolism, Cellular Responses, Reproduction and Brain contains the proceedings of the Satellite Symposium of the 7th International Congress of Pharmacology held at Paris on July 22-23, 1978. Organized into four parts, this book begins with a discussion on the quantification of cannabinoids and their metabolites in the body fluids and tissues. Part II describes the cannabinoids and cellular metabolism. Parts III and IV explain the effects of cannabis on reproduction and brain.

  • Herbicides

    Analytical Methods for Pesticides, Plant Growth Regulators, and Food Additives, Vol. 4
    • 1st Edition
    • Gunter Zweig
    • English
    Analytical Methods for Pesticides, Plant Growth Regulators, and Food Additives, Volume IV: Herbicides contains detailed analytical procedures for analysis of 30 different herbicides and plant growth regulators. Each chapter of this 27-chapter volume covers the chemical and biological properties, history of development, methods of synthesis, and modified residue methods for different crops. Each chapter presents first the general information, followed by intensive discussion of the methods of occurrence and residue analysis. Methods of analysis covered in each chapter include chemical methods, gas-liquid chromatography, colorimetry, and enzymatic techniques. Agriculturists, analytical chemists, and toxicologists will find this book rewarding.

  • Symposium on Clinical Pharmacology

    Biochemical Pharmacology
    • 1st Edition
    • William A. Creasey + 2 more
    • English
    Symposium on Clinical Pharmacology reviews advances in clinical pharmacology, with emphasis on how to materially improve the efficacy of cancer chemotherapy. Topics range from absorption, protein binding, distribution, and excretion of antineoplastic drugs to factors affecting the biotransformation and activity of antitumor drugs. The transport of tumor-inhibitory agents across cell membranes is also examined, together with factors influencing drug selectivity and the mechanisms of clinical drug resistance. This volume is comprised of 23 chapters and begins with a brief summary of the different kinds of pharmacokinetic models and how detailed kinetic investigations of a drug in animals may provide further insight into modes of its clinical use. The next chapter considers the chief factors in determining the effective concentration of a drug at a receptor site as well as the duration and intensity of drug effect, citing antineoplastic agents as examples. The role of enzymatic activation and inactivation in drug selectivity is also discussed, along with the general mechanisms of clinical resistance to cancer chemotherapy; biochemical and pharmacological principles of combination chemotherapy; and the reaction and effects of nitrosoureas. This book will be of interest to clinicians, pharmacologists, and biochemists.

  • The Red Blood Cell

    Volume II
    • 2nd Edition
    • Douglas MacN. Surgenor
    • English
    The Red Blood Cell, Second Edition, Volume II provides a comprehensive treatment and review of basic biomedical knowledge about the circulating, adult red blood cell. This book discusses the transport through red cell membranes; carrier-mediated glucose transport across human red cell membranes; and metabolism of methemoglobin in human erythrocytes. The interaction of oxygen and carbon dioxide with hemoglobin at the molecular level; physiological role of the oxyhemoglobin dissociation curve; hemoglobinopathies; and thalassemia syndromes are also deliberated. This publication likewise covers the red cell genetic polymorphisms; biological life of the red cell; clinical indications for red cells and blood; and biophysical behavior of red cells in suspensions. Other topics include the electrokinetic behavior of red cells; erythrocyte as a biopsy tissue in the evaluation of nutritional status; and knowledge of red cell purine and pyrimidine metabolism coming from the study of human disease. This volume is recommended for students, researchers, teachers, and physicians aiming to acquire knowledge of the red blood cell.

  • Methods of Animal Experimentation

    Volume I
    • 1st Edition
    • William I. Gay
    • English
    Methods of Animal Experimentation, Volume I, provides information on the most common methods for using animals as tools in the search for new biological knowledge. The techniques described will facilitate the most efficient use of research animals and provide guidelines for their utmost comfort and welfare. The text is arranged according to specific research methods rather than to organ system or disease category. This approach gives the reader a broad view of the techniques involved in specific fields and describes the range of usefulness of these techniques. The first five chapters of the present volume describe basic information, methods, and principles involved in managing animals for experimental procedures. The remaining chapters deal with special techniques which have been demonstrated to be distinct, useful methods for using laboratory animals as a basic biomedical research tool. The descriptions of both fundamental and well-developed techniques of animal experimentation in various research fields should be useful to graduate students and experienced scientists who must consider variations in research approaches. The book is a source of information for the scientist administrator who is frequently confronted with different proposed approaches to biological research projects utilizing animals.

  • Radiation Protection and Recovery

    International Series of Monographs on Pure and Applied Biology: Modern Trends in Physiological Sciences
    • 1st Edition
    • Alexander Hollaender
    • English
    Modern Trends in Physiological Sciences, Volume 7: Radiation Protection and Recovery covers the biological, physiological, and biochemical methods created to protect living organisms from radiation damage. This book is composed of 12 chapters that evaluate the methods of protecting macromolecules in vitro against ionizing radiation damage. It addresses the degradation of polymethacrylic acid and the polymerization of vinyl monomers. Some of the topics covered in the book are the chemical protection to mammals against ionizing radiation; chemical protective agents; methods of protection and recovery in bacteria and fungi; and effect of cultural conditions and physiological state on radiosensitivity. Other chapters deal with the experimental modification of radiosensitivity and the role of phase state in inactivitation. These topics are followed by an analysis of the effect of the gaseous environment during irradiation. The chemical protection against inactivation and mutation is also presented. The last chapter is devoted to the environmental factors in radioresistance. The book can provide useful information to doctors, radiologists, students, and researchers.

  • Drug Design

    Medicinal Chemistry: A Series of Monographs, Vol. 10
    • 1st Edition
    • E. J. Ariëns
    • English
    Drug Design, Volume X covers promising and current developments in drug design. The book discusses procedures as applied in the practice of drug design; the structural aspects of the structure-activity relationships of neuroleptics; and promising perspectives in the highly actual field of bioactive peptides. The text also describes the application of the dynamic systems analysis to the antihypertensive drug action; polymeric drug delivery systems; and the design of biocompatible polymers. The structure-activity relationships of insect repellents as a basis for the design of such agents, as well as the approaches to the multivariate data analysis in structure-activity relationships, which is an essential aspect of drug design, are also encompassed. Chemists, pharmacologists, bioengineers, and people involved in drug design and manufacture will find the book invaluable.

  • Biological Organization at the Cellular and Supercellular Level

    A Symposium Held at Varenna, 24–27 September, 1962, under the Auspices of UNESCO
    • 1st Edition
    • R. J. C. Harris
    • English
    Biological Organization at the Cellular and Supercellular Level provides information on some of the most intriguing problems of cell biology. This book discusses the models for gene function as well as the simple mechanisms found in bacteria. Organized into 14 chapters, this book begins with an overview of the model for the regulation of DNA replication. This text then examines the specific properties of an organism, which arise from its catalytic constitution. Other chapters consider the experiments to test whether enzyme induction is accompanied by an increase in the rate of synthesis of the specific messenger RNA corresponding to the structural gene that controls the induced enzyme. This book discusses as well the comparison of the properties of the two types of CO2-sensitive flies, namely, the non-stabilized and the stabilized. The final chapter deals with the morphological or structural aspects of biological organization. This book is a valuable resource for geneticists, embryologists, and cancerologists.

  • Survey of Biological Progress

    Volume 2
    • 1st Edition
    • George S. Avery + 2 more
    • English
    Survey of Biological Progress, Volume II is an eight-chapter text that covers the advances in some biological subjects, including human genetics, plant morphogenesis, histochemistry, and plant reproduction. The opening chapter examines the kinetics of the effect of radiation on living systems. The succeeding chapters explore the developments in the field of human genetics and oceanography. These topics are followed by discussions on the regularity and the specific patterns exhibited in plant morphogenesis; the practical application of plant hormones in horticulture and agriculture; and the technical problems in histochemical studies. A chapter evaluates theoretical and experimental evidence on the fine structure of protoplasm. The final chapter looks into the environmental factors and physiological changes that can be associated with the production of sex structures of all kinds of plants. This book is of great value to biologists, geneticists, researchers, and biology teachers and students.

  • Progress in Chemical Toxicology

    Volume 5
    • 1st Edition
    • Abraham Stolman
    • English
    Progress in Chemical Toxicology, Volume 5 covers topics on the improved isolation and detection procedures and quantitation methods for volatile poisons, stimulants, hallucinogenic drugs, and marihuana. The book discusses the absorption, distribution, and excretion of drugs and poisons and their metabolites; the system for the toxicological analysis of drugs in biological specimens; and the isolation and analysis of phenothiazines. The text also describes the use of fluorescence in toxicology and the toxicology of new synthetic organic polymers used in containers for food, pharmaceutical compounds, and drinkable water. Some microcrystal tests for drugs and advances in polarography as applied to toxicological analysis are also considered. Biochemists, toxicologists, and scientists involved in the study of narcotics will find the book invaluable.

  • Heredity and Environment in the Functional Psychoses

    An Epidemiological–Clinical Twin Study
    • 1st Edition
    • Einar Kringlen
    • English
    Heredity and Environment in the Functional Psychoses involves an epidemiological clinical study of twins carried out at the University Psychiatric Institute in Oslo. The author reviews the history and nosological aspects of psychiatry. In his study of twin genetics, the author seeks to answer the questions "What is inherited?" and "How is it inherited?" In his review of 342 pairs of twins in the Central Register of Psychosis, his study had the following aims: to obtain true concordance figures for all types of functional psychoses; to study problems pertaining to nosology; and to study a larger sample of discordant pairs in order to clarify crucial environmental factors. His findings show that concordance figures for schizophrenia are 25-38 per cent in monozygotic twins and 4-10 per cent ion dizygotic twins. He points out that the difference in such concordance rates between the two types of twins is statistically significant. The data supports the (weak) assumption of a genetic factor in the etiology of schizophrenia. Behavioral scientists, psychiatrists, child psychologists, and researchers involved in genetics will find this book helpful and informative.

  • International Review of Connective Tissue Research

    Volume 1
    • 1st Edition
    • M. A. Epstein
    • English
    International Review of Connective Tissue Research, Volume 1 is a collection of papers that deals with fibroblast, the hormonal control of connective tissues, and calcification of skeletal tissues. One paper reports on the origin, morphology, structure, and the effect of drugs on fibroblasts such as the toxic substance found in sweet pea meal that causes human lathryrism. Another paper discuses hormonal control of connective tissue related to aging, arteriosclerosis, tumors, infection, fertility, and endocrine diseases. The author also describes the repair process of an injured connective tissue; it is characterized by edema, mucinous, and fibrous organization of the extracellular water—a process similar to regeneration and growth. One author describes the structure and general distribution of susceptible blood vessels, as well as, vascular degeneration in diabetes. Another author describes the calcification and formation of bones. He reviews Robison's theory of calcification, the seeding or nucleation concept of calcification, and the role of alkaline phosphatase in calcification. This volume will prove valuable for pathologists, endocrinologists, physiologists, molecular or cellular biologists, gerontologists, and researchers in gene therapy, pharmacology or micro-chemistry.

  • Molecular Cell Pathology

    • 1st Edition
    • G. W. Richter + 1 more
    • English
    International Review of Experimental Pathology, Volume 32: Molecular Cell Pathology discusses the applications and practical value of in situ hybridization; the interactions between endothelial cells and the cells of the immune system; and the molecular biology of cytokine effects on vascular endothelial cells. The text also describes the interphase nucleolar organizer regions in cancer cells; the disease associations, molecular biology, and pathophysiology of antineutrophil cytoplasmic autoantibodies; and the mechanisms and roles of apoptosis in pathology. The molecular events in measles virus infection of the central nervous system are also considered. Pathologists, microbiologists, and immunologists will find the book useful.

  • Mitochondrial Dysfunction

    Methods in Toxicology, Vol. 2
    • 1st Edition
    • Lawrence H. Lash + 1 more
    • English
    Methods in Toxicology, Volume 2: Mitochondrial Dysfunction provides a source of methods, techniques, and experimental approaches for studying the role of abnormal mitochondrial function in cell injury. The book discusses the methods for the preparation and basic functional assessment of mitochondria from liver, kidney, muscle, and brain; the methods for assessing mitochondrial dysfunction in vivo and in intact organs; and the structural aspects of mitochondrial dysfunction are addressed. The text also describes chemical detoxification and metabolism as well as specific metabolic reactions that are especially important targets or indicators of damage. The methods for measurement of alterations in fatty acid and phospholipid metabolism and for the analysis and manipulation of oxidative injury and antioxidant systems are also considered. The book further tackles additional methods on mitochondrial energetics and transport processes; approaches for assessing impaired function of mitochondria; and genetic and developmental aspects of mitochondrial disease and toxicology. The text also looks into mitochondrial DNA synthesis, covalent binding to mitochondrial DNA, DNA repair, and mitochondrial dysfunction in the context of developing individuals and cellular differentiation. Microbiologists, toxicologists, biochemists, and molecular pharmacologists will find the book invaluable.

  • Plate Tectonics & Crustal Evolution

    • 2nd Edition
    • Kent C. Condie
    • English
    Plate Tectonics & Crustal Evolution, Second Edition covers the role of plate tectonics in the geologic past in light of existing geologic evidence, and examples of plate reconstructions. The book discusses the important physical and chemical properties of the crust and upper mantle in terms of models for crustal origin and evolution. The text also describes sea-floor spreading; magma associations; plate tectonics and continental drift. The phanerozoic orogenic systems and the precambrian crustal development are also tackled. The book will be invaluable to students in the earth sciences and to various specialists in the geological sciences.

  • Blood Cells and Plasma Proteins

    Their State in Nature
    • 1st Edition
    • James L. Tullis
    • English
    Blood Cells and Plasma Proteins: Their State in Nature focuses on the properties, characteristics, reactions, and transformations of blood cells and plasma proteins. The selection first takes a look at the historical prologue on the discovery of the formed and fluid parts of human blood and chemical prologue on the characterization and separation of proteins by virtue of their interactions with neutral salts. The text then takes a look at interactions of proteins with each other and with heavy metals and interactions of proteins with alkaline earths, steroids, blood cells, and polysaccharides. The book then ponders on the components of human plasma concerned with coagulation and the biochemical, physiological, and pathological aspects of the coagulation mechanism. Discussions focus on evolution of the clotting mechanism, modern concepts of clotting, state of accelerator substances, and state of calcium. The text also tackles the nature of immune processes, antibodies in human gamma globulin, and physical characteristics of the gamma globulins. The selection is a valuable reference for readers interested in blood cells and plasma protein.

  • Toxic Phosphorus Esters

    Chemistry, Metabolism, and Biological Effects
    • 1st Edition
    • Richard D. O'Brien
    • English
    Toxic Phosphorus Esters: Chemistry, Metabolism, and Biological Effects aims to become a source book on organophosphate research and show how the understanding of the events following organophosphate poisoning of animals can be understood in terms of events at the molecular level. The manuscript first offers information on nonenzymic reactions and the reaction with cholinesterase in vitro. Discussions focus on hydrolysis, isomerization, oxidation, phosphorylation of the enzyme, and selectivity for different cholinesterases. The text then examines enzymic degradation and activation in vitro, effects in mammals, and effects on isolated whole tissues. The publication ponders on the effects in insects and plants, including results of poisoning, metabolism, resistance, antagonism and synergism, and phytotoxicity. The text also reviews selective toxicity, as well as excretion and storage, metabolism, design of new selective compounds, and nature of the target. The manuscript is a dependable reference for readers interested in the composition, reactions, and effects of toxic phosphorus esters.

  • International Review of General and Experimental Zoology

    Volume 2
    • 1st Edition
    • William J. L. Felts + 1 more
    • English
    International Review of General and Experimental Zoology, Volume 2 is a collection of world literature concerning developments in general and experimental zoology. This book is composed of six chapters, and begins with a survey of the biochemical and serological techniques and their application in experimental taxonomy. The succeeding chapters review the field of general and comparative endocrinology in lower vertebrates, as well as the problems of understanding the fine structure of the synaptic cleft of presumed chemically transmitting synapses. These topics are followed by discussions on structural and functional aspects of the avian lungs and air sacs; the metabolic aspect of heat transfer in biological systems; and the external energy transfer from the organism to the surrounding environment. The final chapter focuses on the experimental studies of neurocranium morphology and growth. This book will prove useful to zoologists and taxonomists.

  • Agricultural Decision Making

    Anthropological Contributions to Rural Development
    • 1st Edition
    • Peggy F. Barlett
    • English
    Agricultural Decision Making: Anthropological Contributions to Rural Development presents the impact of farmers' choices in agricultural production. This book discusses how individual decisions determine household profits and well-being, capital requirements, land use, and the adoption of technology. Organized into three parts encompassing 14 chapters, this book begins with an overview of the theoretical and methodological questions concerning the use of formal models in evaluating the alternatives open to farmers. This text then explores the patterns of agricultural choices within one rural community. Other chapters consider the implications of decision-making research for agricultural development policy and explore the decision-making context of aid programs. This book discusses as well the impacts of nonagricultural alternatives on agricultural decisions. The final chapter deals with various policy and development programs for agricultural development. This book is a valuable resource for economic anthropologists, historians, economists, agricultural economists, rural sociologists, psychologists, farmers, and research workers.

  • International Review of Forestry Research

    Volume 2
    • 1st Edition
    • John A. Romberger + 1 more
    • English
    International Review of Forestry Research, Volume 2 is a collection of reviews and summaries of world literature concerning trees, forests, and forestry. This volume is divided into six chapters, and begins with a brief presentation of the historical developments of forest science and forestry research in East Asia. The succeeding chapters evaluate the influence of spacing on the growth and development of different coniferous tree species, as well as the influence of silvicultural practices on wood quality. These topics are followed by discussions on the various aspects of forest meteorology and the optimal conditions for vigorous root growth. The final chapter looks into the successions of organisms in discoloration and decay processes in living trees. This book will prove useful to forest scientists, research workers, teachers, advanced students, administrators, economists, and forest and land managers.

  • The Nervous System

    Autonomic Nervous System Drugs
    • 1st Edition
    • Walter S. Root + 1 more
    • English
    Physiological Pharmacology: A Comprehensive Treatise, Volume III: The Nervous System — Part C: Autonomic Nervous System Drugs focuses on the effects of drugs on the nervous system, including cardiovascular effects and metabolism. The selection first offers information on the cardiovascular effects of choline esters and the effects of choline esters on smooth muscles and secretions. Topics include actions of acetylcholine, physiological role of choline esters, and actions of cholinergic drugs on smooth muscles and secretions. The book also takes a look at the pharmacologic, toxicologic, and therapeutic properties of anticholinesterase agents, including the chemistry and metabolism of anticholinesterase substances and mechanisms of action of anticholinesterase agents and role of cholinesterases. The publication examines muscarinic blocking drugs and ganglion-blocking drugs. Discussions focus on actions on the secretory glands and cardiovascular system; distribution, metabolism, and excretion of atropine; substances that block ganglionic transmission; and cardiovascular effects. The text also elaborates on neuromuscular blocking drugs. The selection is a dependable reference for readers interested in the effects of drugs on the nervous system.

  • Essays in Toxicology

    Volume 5
    • 1st Edition
    • Wayland J. Hayes
    • English
    Essays in Toxicology, Volume 5 covers essays in toxicology. The book presents essays on nitrosamines; a laboratory model ecosystem to evaluate compounds producing biological magnification; and the metabolism of DDT in human. The text also includes essays on the toxins of Clostridium botulinum; the use of breath analysis in clinical toxicology; and the biochemical toxicology of methanol. Toxicologists, biochemists, microbiologists, pharmacologists, and people involved in the research of toxicology will find the book invaluable.

  • Biology in Profile

    A Guide to the Many Branches of Biology
    • 1st Edition
    • P. N. Campbell
    • English
    Biology in Profile: A Guide to the Many Branches of Biology is a 20-chapter text that describes the profile and biological phenomena of selected branches of biology. Each chapter discusses the scope, growth areas, and specialties of the specific branch of biology. This book includes 20 branches of biology, such as zoology, botany, microbiology, physiology, ecology, ethology, psychology, parasitology, pharmacy, and pharmacology. Other branches covered include toxicology, nutrition, food science, endocrinology, immunology, genetics, virology, biophysics, biochemistry, and molecular biology. This book will be of value to students and other scientists who are not practicing biologists.

  • Neurologic Emergencies in Infancy and Childhood

    • 2nd Edition
    • John M Pellock + 1 more
    • English
    This second edition of Neurologic Emergencies in Infancy and Childhood is written in response to colleagues who have requested an updated version of the book because of numerous advances in child neurology and medicine in general since the first offering. The chapters were designed for easy use in emergency and general medical situations and all chapters have been revised, rewritten, or replaced. This book is organized into 21 chapters written by 31 contributors. A separate section on spinal cord disorders has greatly expanded the previous chapter on myelomeningocele and it includes a discussion on spinal cord trauma and other causes of paraplegia. A separate chapter on psychiatric emergencies possibly presenting with neurologic signs or symptoms has been added. The chapters also contain information concerning drug dosages and the use of newer agents, including antibiotics, antiepileptics and other drugs. This book will be of interest to persons dealing with studies on the management of neurologic emergencies.

  • Neural Models of Plasticity

    Experimental and Theoretical Approaches
    • 1st Edition
    • John H. Byrne + 1 more
    • English
    Neural Models of Plasticity: Experimental and Theoretical Approaches is an outgrowth of a conference that was held at Woods Hole, Massachusetts, in the spring of 1987. The purpose of that conference was to review recent developments in both areas and to foster communication between those researchers pursuing theoretical approaches and those pursuing more empirical approaches. Contributions have been solicited from individuals who represent both ends of the spectrum of approaches as well as those using a combination of the two. These indicate that our knowledge of the plastic capabilities of the nervous system is accelerating rapidly due to rapid advances in the understanding of basic subcellular and molecular mechanisms of plasticity, and because of the computational capabilities and plastic properties that emerge from neural networks and assemblies. The book contains 19 chapters and opens with a study on the role of the neuromodulator in associative learning of the marine mollusk Hermissend. Subsequent chapters examine topics such as learning and memory in Aplysia; the Hebb rule for synaptic plasticity; olfactory processing and associative memory in the mollusk Limax maximus; simulation of a classically conditioned response; and the neural substrates of memory, focusing on the role of the hippocampus.

  • The Nervous System

    Central Nervous System Drugs
    • 1st Edition
    • Walter S. Root + 1 more
    • English
    Physiological Pharmacology: A Comprehensive Treatise, Volume II: The Nervous System — Part B, Central Nervous System Drugs focuses on the effects of drugs on the functions of the central nervous system. The selection first offers information on depressant and anticonvulsant drugs. Topics include neurophysiological substrate of drug action; pharmacological properties of selected muscle relaxants; anticonvulsants and their mechanisms; and definitive seizure mechanisms. The book also takes a look at antitussive drugs and psychic energizers and antidepressant drugs. The publication examines emetic and antiemetic drugs, as well as neural mechanisms of emesis, emetic syndromes and agents, and antiemetic agents. The text also reviews the effects of drugs on the eyes and synoptic transmission in the central nervous system. Discussions focus on the effect of drugs used in the therapy of ocular disease; undesirable eye effects of ophthalmic and other drugs; and chemical transmitters in the central nervous system. The selection is a dependable reference for readers interested in the effects of drugs on the central nervous system.

  • Electrophysiological Methods

    Physical Techniques in Biological Research
    • 1st Edition
    • William L. Nastuk
    • English
    Physical Techniques in Biological Research Volume VI: Electrophysiological Methods presents the analytical methods and experimental techniques in electrophysiological research. It discusses the handling and analysis of information by computer methods. It addresses the methods of analysis of waveforms, signal characterization and detection. Some of the topics covered in the book are the fundamentals of digital and analog computers; analysis of complex waveforms; operational amplifiers; signal processing and parameter estimation; the core conductor model; voltage clamp techniques; cable theory; automatic computation equipment; and electric accounting machinery. The wave shape generation are covered. The characterization of systematic functions is discussed. The text describes the nerve containing axial wire. A study of the internal thin and outer diffuse electrodes is presented. A chapter is devoted to the simple one dimensional model. Another section focuses on the cylindrical model with radial symmetry and accuracy of membrane potential measurement. The book can provide useful information to experimenters, students, and researchers.

  • Electrophysiological Methods

    Physical Techniques in Biological Research
    • 1st Edition
    • William L. Nastuk
    • English
    Electrophysiological Methods presents a compilation of essays relating to the field of electricity. One topic is the introduction and analysis of electrical stimulation. Other types of stimulation are thermal stimulation, light stimulation, touch stimulation, and auditory stimulation. Microelectrodes act as links by which small regions in biological tissues are electrically joined to amplifying and recording devices. This topic is explored more thoroughly in the book. The physiological activity of cells in nerves, muscles, secretory organs, and other biological structures is accompanied by electrical changes which appear across the cell membrane. This occurrence is another topic in the text. Intracellular techniques employed to record transmembrane potentials and to stimulate cells are likewise presented. A section of the book presents microelectrophoresis which is a method wherein electrical flow is employed to manipulate the ejection of chemical substances from fine microelectrodes or micropipettes. The book will provide useful information to neurologist, cytologist, doctors, students, and researchers in the field of medicine.

  • Electron-Microscopic Structure of Protozoa

    International Series of Monographs on Pure and Applied Biology: Zoology
    • 1st Edition
    • D. R. Pitelka
    • G. A. Kerkut
    • English
    Electron-Microscopic Structure of Protozoa mainly discusses the structure and taxa of protozoa. This text first discusses protozoa as cells, wherein the author emphasizes that these unicellular organisms be compared with a whole metazoan organism than with any of its component cells. This book then studies the protozoan superclass Rhizopoda, subphylum Actinopoda, slime molds, and subphylum Sporozoa, as well as toxoplasma. Phytoflagellates, zooflagellates, and ciliates are also tackled. This book concludes by explaining membrane differentiations, fibrous structures, and relationships of protozoa. This publication will be invaluable to biologists and other scientists interested in studying protozoa.

  • Sectional Anatomy and Tomography of the Head

    • 1st Edition
    • Guy D. Potter
    • English
    Sectional Anatomy & Tomography of the Head focuses on the anatomical section of the head and its description. It discusses the slowly developing appearance of the head which includes the face, orbit, ears, sinuses, and base of the skull. It addresses the functions and structures of such parts. Some of the topics covered in the book are the anatomic section, radiographs, line drawings, and tomography of the coronal head, the lateral head, axial head, and oblique head. The frontal, lateral, axial, and oblique positions of the head are covered. A study of the axial features of the head is also presented. A chapter is devoted to the bone structures of the oblique area of the head. Another section focuses on the description of orbit, optic canal, nasal fossa, and temporal bone. The book can provide useful information to doctors, neurosurgeons, students, and researchers.

  • The Control of Chromatophores

    International Series of Monographs on Pure and Applied Biology
    • 1st Edition
    • M. Fingerman
    • English
    The Control of Chromatophores focuses on the color changes in animals, particularly among the invertebrates. Cells containing pigment that can disperse or concentrate, thereby changing the tint of the organism in which they lie, are known as chromatophores. Well-developed, functional chromatophore systems are common among cephalopods, crustaceans, and poikilotherm vertebrates. Rare instances are found among other groups such as annelids, echinoderms, and insects. After an introduction to the types, chemistry, and functional significance of chromatophores, this text concentrates on the chromatophores of crustaceans, insects, cephalopods, echinoderms, and vertebrates. This book is recommended for students and biologists conducting work on chromatophores and color changes.

  • International Review of Neurobiology

    Supplement 1
    • 1st Edition
    • Carl C. Pfeiffer
    • English
    International Review of Neurobiology, Supplement 1: Neurobiology of the Trace Metals Zinc and Copper represents a first report in the study of the neurobiology of zinc and copper. Topics covered by this supplementary volume include the effects of zinc deficiency; the link between acute stress and trace element metabolism; the effects of trace elements on behavior; the pathophysiology of zinc; and the role of copper in schizophrenia. This book consists of seven chapters and begins with a historical overview of zinc deficiency syndrome in humans, followed by a discussion on the metabolism of zinc, effects of its deficiency, and its biochemical functions. Gross congenital malformations in zinc-deficient rats are highlighted. The reader is then introduced to the effect of acute stress on the metabolism of a trace element; the importance of trace elements to development and behavior; and the biological effect(s) of zinc. The next chapter is devoted to idiopathic hypogeusia with dysgeusia, hyposmia, and dysosmia, its symptoms, clinical pathology, and treatment. This monograph will be of value to neurobiologists, biochemists, and nutritionists.

  • Advances in Cellular Neurobiology

    Volume 5
    • 1st Edition
    • Sergey Fedoroff
    • English
    Advances in Cellular Neurobiology, Volume 5 focuses on cellular neurobiology, drawing on some aspects of biochemistry, endocrinology, embryology, morphology, genetics, pharmacology, pathology, and physiology. This book deals with humoral influences on brain development. Organized into three sections encompassing 10 chapters, this volume begins with an overview of the proposed functions for neurohumoral agents, including cell division, neural tube closure, palate formation, myoblast differentiation, and regulation of cell movements. This text then examines how growth factors regulate autonomic nerve development. Other chapters consider the morphology, physiology, and biochemistry of the neuronal cytoskeleton. This book discusses as well the connective tissue components in the normal peripheral nervous system and in two pathological conditions. The final chapter deals with the advantages and preparation of monoclonal antibodies in the identification of neurons. This book is a valuable resource for neurobiologists and researchers. Scientists in all fields of life sciences will also find this book useful.

  • Neuropeptide Analogs, Conjugates, and Fragments

    Methods in Neurosciences, Vol. 13
    • 1st Edition
    • P. Michael Conn
    • English
    Methods in Neurosciences, Volume 13: Neuropeptide Analogs, Conjugates, and Fragments covers the synthesis and characterization of peptide analogs, conjugates, and fragments, their use as ligands for receptors, and their role in the development and use of antisera. The book discusses techniques such as novel synthetic approaches; biotinylation; purification and characterization; radioligand techniques and assay development; use of agonists and antagonists; distinguishing receptor subtypes; conjugation to carrier proteins; antiidiotypic antibody development; and radiolabeling. Neuroscientists, biochemists, neurochemists, and pharmacologists will find the book useful.

  • Screening Methods in Pharmacology

    Volume II
    • 1st Edition
    • Robert Turner + 1 more
    • English
    Screening Methods in Pharmacology, Volume II is a collection of papers that presents practical techniques and information on the selection of a screening program for a particular pharmacological activity. The book contains the most reliable, simplest, and the most preferred screening methods in pharmacology. The text presents screening methods for alpha and beta Adrenergic blocking agents; compounds for antianginal activity; topical products for excessive eccrine sweating; antidepressant agents; and agents with analgesic and analgesic antagonist activity. Pharmacologists, pharmacists, researchers, and physicians will find this book a good source of information.

  • The Physiology of Synapses

    • 1st Edition
    • John Carew Eccles
    • English
    The Physiology of Synapses covers the considerable advances in understanding the complex physiology of synapses. This book is divided into 16 chapters that emphasize the mechanism of synaptic transmission. The first chapters describe the structural and physiological features of chemically transmitting synapses. The subsequent chapters deal with the excitatory postsynaptic responses to presynaptic impulse and the release of transmitter by presynaptic impulses. These topics are followed by discussions of the impulse generation by the excitatory postsynaptic potential; the postsynaptic electrical events produced by chemically transmitting inhibitory synapses; the ionic mechanism generating the inhibitory postsynaptic potential. The last chapters consider the mechanism of inhibitory transmitter substances, pathways responsible for postsynaptic inhibitory action, and the trophic and plastic properties of synapses. This book will prove useful to physiologists, neurologists, and researchers.

  • Brain Receptor Methodologies

    Amino Acids. Peptides. Psychoactive Drugs
    • 1st Edition
    • Paul J. Marangos + 2 more
    • English
    Brain Receptor Methodologies: Part B Amino Acids. Peptides. Psychoactive Drugs is the second of the two-part first volume of the Neurobiological Research series, which provides a comprehensive view of various subdisciplines within neurobiology. The first volume (Parts A and B) deals with the area of neurotransmitter and neuromodulator receptors in brain; future volumes will cover the subdisciplines of neuroanatomy, neurophysiology, brain-specific macromolecules, neurochemistry, and behavioral neurobiology. It is hoped that the series will be of equal value for both basic as well as clinical scientists Part B continues from Part A with the remainder of Section II, specific receptor binding methodologies. Subsection II,B deals with receptors for amino acids and neuropeptides and covers areas including GABA, glycine, carnosine, opiates, bombesin, CCK, TRH, and substance P. Amino acids probably represent the majority of brain neurotransmitter substances, at least relative to the amines and acetylcholine, although with the exception of GABA, the amino acids remain relatively uncharacterized in brain. Their further study should receive high priority.

  • Histological Techniques for Electron Microscopy

    • 2nd Edition
    • Daniel C. Pease
    • English
    Histological Techniques for Electron Microscopy, Second Edition, offers a practical guide for those who would study cells or tissues with an electron microscope. The book contains 11 chapters and begins with a discussion of the organization and management of an electron microscope laboratory. This is followed by separate chapters on tissue preservation; fixatives and their variations; methacrylate embedding and cross-linked plastics, microtomes and microtomy; and section mounting. Subsequent chapters deal with the techniques of "staining" for electron microscopy, photography; mounting, shadowing, and replication; and negative staining.

  • Essays in Toxicology

    Volume 2
    • 1st Edition
    • Frank R. Blood
    • English
    Essays in Toxicology, Volume 2 covers essays on toxicology and related topics. The book presents essays on fungal toxins, such as mycotoxin, aflatoxin, moldy corn toxicoses, alimentary toxic aleukia, ochratoxin, sporidesmin, zearalenone and other estrogenic compounds, pink rot dermatitis, and slaframine. The text also includes essays on hyperbilirubinemia and cholestasis induced by alpha-naphthylisothi... taurolithocholic acid, and 2-ethyl-2-phenyl butyramide, as different forms of liver injury produced in animals. The evolution of pesticide analyses is also encompassed. Biochemists, physiologists, pathologists, and microbiologists will find the book invaluable.

  • The Plasma Proteins

    Structure, Function, and Genetic Control
    • 2nd Edition
    • Frank W Putnam
    • English
    The Plasma Proteins: Structure, Function, and Genetic Control, Second Edition, Volume II describes the plasma proteins in a systematic and integrated way, with emphasis on structure, function, and genetic control. The text presents the perspectives and a global look at plasma proteins; well-characterized major proteins; and integrated systems of plasma proteins. The emphasis of the studies is mainly on human proteins. Clinical relevance is introduced in terms of principles rather than detail. Biochemists, molecular biologists, physiologists, and laboratory researchers in the field of medicine will find the book useful.

  • Calcium and Cell Function

    • 1st Edition
    • Wai Yiu Cheung
    • English
    Calcium and Cell Function, Volume V emphasizes the roles of calcium in cellular functions. This book consists of eight chapters. Chapter 1 presents evidence for the role of calmodulin in cell proliferation. The role of calcium in the control of cyclic AMP metabolism in glial and pituitary tumor cells is analyzed in Chapter 2. Chapter 3 explains the evidence that calmodulin regulates neurotransmitter synthesis, while Chapter 4 deliberates the role of calcium in adipocytes. Chapter 5 is devoted to the modulatory function of lipomodulin in cellular phospholipid metabolism. The pharmacological properties of naphthalenesulfonami... as calmodulin antagonists, phophorylase kinase, and phospholipidsensitiv... calcium-dependent protein kinase are reviewed in the last chapters. This volume is valuable to biologists and medical practitioners interested in calcium and cell function.

  • Cellular and Molecular Mechanisms of Inflammation

    Vascular Adhesion Molecules
    • 1st Edition
    • Charles G. Cochrane + 1 more
    • English
    Cellular and Molecular Mechanisms of Inflammation: Vascular Adhesion Molecules presents the study of the structure and function of constitutive and inducible cell surface structures, which contribute to the temporal and spatial patterns, and cellular selectivity of leukocyte-vessel wall interactions. The book addresses the rapidly expanding field of vascular adhesion molecules. Contributed articles discuss SELECTINS, a family of structurally related glycoproteins that contain lectin like domains that confer leukocyte-selective adhesive functions, which include ELAM-1 (Endothelial-Leukocy... Adhesion Molecule-1), GMP-140 (PADGEM, CD62), and LAM-1 (gp 90m e l, LEC-CAM-1, LECAM-1). Other adhesive molecules such as CD44 and members of the immunoglobulin family of cell surface glycoprotiens, including ICAM-1 (CD54), VCAM-1/ INCAM-110 and LP AM-1 are also considered. The text will be very useful to cytologists, molecular biologists, physiologists, and pharmacologists.

  • Clinical Neuroendocrinology

    • 1st Edition
    • G. M. Besser + 1 more
    • English
    Clinical Neuroendocrinology, Volume II discusses neuroendocrine science and its application to the analysis of human physiology and behavior. This book stresses the importance of the interrelationships between central and peripheral signals, neurotransmitters and neuromodulators, and target glands and peripheral tissues to ensure coordination of somatic and behavioral development and function. The ""centralist"" concepts of the importance of brain hormones are revised in this text, emphasizing that neurohumoral factors isolated from brain tissues, and initially considered to be primarily involved in the central nervous system regulation of the endocrine system, also exist outside the brain and spinal cord. This volume is valuable to neuroendocrinologist... but is also a good source for those involved in basic and clinical research and patient management.

  • Special Methods

    Physical Techniques in Biological Research
    • 1st Edition
    • William L. Nastuk
    • English
    Physical Techniques in Biological Research, Volume IV: Special Methods presents the methods of determining body fluid volume. This book is composed of six chapters that discuss the techniques of vascular perfusion and evaluate the nature of the electrode reaction. It also demonstrates the certain characteristics of the oxygen cathode. Some of the topics covered in the book are the methods for pressure measurement; techniques in gas volume measurement; modes of gas flow measurement; applications of pressure, volume, and flow measurements; and procedures for gas analysis. Other chapters deal with the contents of perfusion media, the determination of extracellular fluid volume, and an analysis of the components of perfusion apparatus. Applications of ultrasonic fields to the study and alterations of biological systems are presented. The last chapter is devoted to the developments made in the use of flame photometry and its description. The book can provide useful information to doctors, students, and researchers.

  • Drugs and Driving

    • 1st Edition
    • Herbert Moskowitz
    • English
    Drugs and Driving is a compendium of papers from a symposium of the same title presented at the U.S. Transportation Research Board. This collection reviews the effects of five classes of drugs on driving (amphetamines, tranquilizers, barbiturates, narcotics, cannabis), the other studies being made on drugs and driving, as well as some countermeasure programs against drunk driving. The papers report that amphetamines can induce risky driving behavior, tranquilizers can increase traffic accident risks, barbiturates can degrade driving skills especially when the drug is combined with alcohol, while marijuana use can impair important driving skills. Another paper evaluates drug use and driving risk among high school students in Toronto: results show that the total effect of infrequent use of drugs on accidents is small compared to alcohol use. A study of out-patients in Finland notes that the combined used of alcohol and drugs tend to increase accident frequency. One paper refutes that Alcohol Safety Action Programs in the United States are ineffective. This collection can be helpful for sociologist, psychologists, psychiatrists, traffic safety officers, and heads of urban safety and traffic divisions.

  • Bioreduction in the Activation of Drugs

    Proceedings of the Second Biochemical Pharmacology Symposium, Oxford, UK, 25-26 July 1985
    • 1st Edition
    • P. Alexander + 2 more
    • English
    Bioreduction in the Activation of Drugs covers the proceedings of the Second Biochemical Pharmacology Symposium. The book presents papers that cover the applications of bioreduction in drug activation, along with its concerns. The text first presents materials about enzymology, such as overview of enzyme systems involved in bioreduction of drugs and in redox cycling, and reductive role of glutathione in the redox cycling of oxidizable drugs. Next, the book covers papers on bacterial and parasites infection, which include reduction by the gut microflora of animals and human and reduction of nitroimidazoles in vitro and DNA damage. The remaining articles deal with cancer treatment, such as hypoxia-mediated nitro-heterocyclic drugs in the radio- and chemotherapy of cancer, and the biological properties of reduced nitroheterocyclics and possible underlying biochemical mechanisms. The text will be of great use to researchers and practitioners of medicine, pharmacology, and biochemistry.

  • Modern Trends in Diseases of the Ear, Nose and Throat

    Modern Trends Series
    • 1st Edition
    • Maxwell Ellis
    • English
    Modern Trends in Diseases of the Ear, Nose, and Throat presents a critical review of speech therapy for children with cleft palate. The book discusses the development and treatment of cancer of the larynx, as well as the condition of a patient after laryngectomy. Some of the topics covered in the text are the radiology of the ear, nose, and throat; the description of the pharyngeal diverticulum and laryngeal paralysis; and the mechanisms of larynx stenosis. The development of tuberculosis of the upper air passages; the physiology of the esophagus; and the diagnosis of facial paralysis are also considered. The book further tackles the intracranial complications of the aural infections; the characteristics of chronic otorrhea; and the description of the upper respiratory tract infection in children. The orbital complications of sinus infections and the tumors of the nasopharynx are also presented. A chapter is devoted to the chemotherapy of acute aural infection. The book can provide useful information to surgeons, doctors, students, and researchers.

Related subjects