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Molecular Cell Pathology
- 1st Edition - October 22, 2013
- Editors: G. W. Richter, Kim Solez
- Language: English
- Paperback ISBN:9 7 8 - 1 - 4 8 3 2 - 0 4 9 8 - 7
- eBook ISBN:9 7 8 - 1 - 4 8 3 2 - 1 8 4 1 - 0
International Review of Experimental Pathology, Volume 32: Molecular Cell Pathology discusses the applications and practical value of in situ hybridization; the interactions… Read more
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Request a sales quoteInternational Review of Experimental Pathology, Volume 32: Molecular Cell Pathology discusses the applications and practical value of in situ hybridization; the interactions between endothelial cells and the cells of the immune system; and the molecular biology of cytokine effects on vascular endothelial cells. The text also describes the interphase nucleolar organizer regions in cancer cells; the disease associations, molecular biology, and pathophysiology of antineutrophil cytoplasmic autoantibodies; and the mechanisms and roles of apoptosis in pathology. The molecular events in measles virus infection of the central nervous system are also considered. Pathologists, microbiologists, and immunologists will find the book useful.
Contributors
Applications of in Situ Hybridization
I. Introduction
II. Methodology
III. Applications
IV. Practical Value for Histopathology
References
Interactions between Endothelial Cells and the Cells of the Immune System
I. Introduction
II. Interactions between Endothelial Cells and Immune System Cells in the Control of Coagulation
III. Lymphocyte/Endothelial Cell Interactions in Lymphocyte Recirculation
IV. Interactions between Endothelial Cells and Immune System Cells in the Regulation of Mononuclear Cell Migration into Inflammatory Lesions
V. The Role of Cytokines in the Activation of Endothelial Cells at Sites of Inflammation
VI. The Effects of Cytokines on Endothelial Cell Expression of MHC Antigens and Their Possible Role in Endothelial Cell Antigen Presentation
VII. Endothelial Cell Proliferation and Angiogenesis
VIII. Effects of Endothelial Cell Products on the Function of Immune System Cells
IX. Conclusions
References
Molecular Biology of Cytokine Effects on Vascular Endothelial Cells
I. Introduction
II. Molecular Basis of Cytokine Responsiveness of Vascular Endothelial Cells
III. Regulation and Induction of Endothelial Gene Expression by Cytokines
IV. Endothelial Gene Expression in in Vivo and in Situ Hybridization
V. Future Directions of Research
References
Interphase Nucleolar Organizer Regions in Cancer Cells
I. Introduction
II. Silver Staining Techniques for the Visualization of NORs
III. General Factors Influencing the Specificity of the Silver Stain for NORs
IV. Molecular Components Responsible for Silver Staining
V. NORs Not Stained by the Ag-NOR Techniques
VI. Localization of NORs in Interphase Nucleoli
VII. Structure and Function of Interphase NORs
VIII. Nucleolar Morphology
IX. Interphase NOR Distribution
X. Distribution of Silver-Stained Interphase NORs in Neoplastic Cells
XI. Is the High Number of Interphase NORs a Peculiar Feature of Cancer Cells
XII. Relationship between Interphase NOR Distribution and Neoplastic State of the Cell
XIII. Structural Changes of Ribosomal Genes in Cells Stimulated to Proliferate
References
Antineutrophil Cytoplasmic Autoantibodies: Disease
I. Introduction
II. Clinical and Pathologic Spectrum of ANCA-Associated Diseases
III. Elucidation of ANCA Antigen Specificity
IV. Pathogenetic Potential of ANCAs
V. Conclusion
References
Apoptosis: Mechanisms and Roles in Pathology
I. Introduction
II. Morphology
III. Mechanisms
IV. Roles in Pathology
V. Conclusions
References
Molecular Events in Measles Virus Infection of the Central Nervous System
I. Introduction
II. Clinical and Epidemiological Features
III. Pathology of Measles-Infected Brain Tissue
IV. Properties of Measles Virus
V. Viral Protein Expression
VI. Viral Gene Expression
VII. Role of Antibodies in Viral Persistence
VIII. CNS Damage by Measles Virus
IX. Concluding Remarks
References
Index
- No. of pages: 296
- Language: English
- Edition: 1
- Published: October 22, 2013
- Imprint: Academic Press
- Paperback ISBN: 9781483204987
- eBook ISBN: 9781483218410
KS
Kim Solez
Affiliations and expertise
Department of Laboratory Medicine and Pathology, University of Alberta, EdmontonRead Molecular Cell Pathology on ScienceDirect