Marihuana Biological Effects
Analysis, Metabolism, Cellular Responses, Reproduction and Brain
- 1st Edition - October 30, 1979
- Latest edition
- Editors: Gabriel G. Nahas, William D. M. Paton
- Language: English
Marihuana Biological Effects: Analysis, Metabolism, Cellular Responses, Reproduction and Brain contains the proceedings of the Satellite Symposium of the 7th International Congress… Read more
Marihuana Biological Effects: Analysis, Metabolism, Cellular Responses, Reproduction and Brain contains the proceedings of the Satellite Symposium of the 7th International Congress of Pharmacology held at Paris on July 22-23, 1978. Organized into four parts, this book begins with a discussion on the quantification of cannabinoids and their metabolites in the body fluids and tissues. Part II describes the cannabinoids and cellular metabolism. Parts III and IV explain the effects of cannabis on reproduction and brain.
Contents
List of Participants
Foreword
Introduction
Marihuana and The Cell—Gabriel Nahas
I. Quantification of Cannabinoids and their Metabolites in Body Fluids and Tissues: Pharmacokinetics
Introduction to Quantification of Cannabinoids and their Metabolites in Biological Fluids
Applications of Mass Spectrometry in Cannabinoid Research
Identification and Measurement of Cannabinoids and their in Vivo Metabolites in Liver by Gas Chromatography—Mass Spectrometry
Relation Between Effects of Cannabinoid Derivatives On The Twitch Response of the Isolated Guinea Pig Ileum and their Psychotropic Properties
Delta-7-Tetrahydrocannabinol, A Non-Psychotropic Cannabinoid: Structureactivity Considerations in the Cannabinoid Series
The Radioimmunoassay of Cannabinoids; Its Clinical, Pharmacological and Forensic Applications
Determination of Cannabinoids in Urine by Emit Homogenous Enzyme Immunoassay
In Vitro Metabolism of Tetrahydrocannabinol by Rhesus Monkey Liver and Human Liver
Pharmacokinetics and Disposition of Delta-9-Tetrahydrocannabinol and Its Metabolites
Summary of Session
II. Cannabinoids and Cellular Metabolism
A. Isolated Cell Preparations
Inhibitory Effects of Delta-9-Tetrahydrocannabinol and Other Psychotropic Drugs On Cultured Lymphocytes
Inhibition by Thc of Thymidine Transport: A Plasma Membrane Effect
Effect of Delta-9-Tetrahydrocannabinol in Nucleoside and Amino Acid Uptake in Reuber H35 Hepatoma Cells
Cannabinoids: The Influence On Cell Proliferation and Macromolecular Biosynthesis
Difference in Response to Vitamin C Between Marihuana and Tobacco Smoke Exposed Human Cell Cultures
Marihuana and Cell Function—R. A. Carchman
Effect of (—) Delta-9-THC On ATPase Systems From Various Sources
(—)Trans-Delta-9-Tetrahydrocannabinol: Synaptosomal Phospholipids, Synaptosomal Plasma Membrane (Na+-K+)-ATPase, and Thiopentone Anaesthesia in Mice
Biochemical Alterations Induced by Cannabinoids in the Leydig Cells of the Rat Test Is in Vitro: Effects On Testosterone and Protein Synthesis
Influence of Delta-9-Tetrahydrocannabinol On Contraction Rate and Enzymatic Activity of Embryonic Heart Cells
B. In Vivo Preparations
Effects of Cannabis On Lungs
An Experimental Animal Model For Quantifying the Biologic Effects of Marijuana on the Defense System of the Lung
Cannabinoids and Membrane-Bound Enzymes
The Effects of Cannabinoids On Rat Brain Synaptosomes
The Effect of in Vivo Treatment With ( — ) Delta-1-Tetrahydrocannabinol, and other Psychoactive Drugs On the in Vitro Uptake of Biogenic Amines
Long Term Effects of Delta-9-Tetrahydrocannabinol in Mice
Hypoploid Metaphases in Cultured Lymphocytes of Marihuana Smokers
Observations in Chronic Hashish Users: Nuclear Aberrations in Blood and Sperm and Abnormal Acrosomes in Spermatozoa
Summary of Session II
III. Cannabis and Reproduction
Effects of Cannabis On Sex Hormones and Testicular Enzymes of The Rodent
Effects of Cannabinoids On Spermatogenesis in Mice
Effects of Marihuana Inhalation On Spermatogenesis of The Rat
Changes in Human Spermatozoa Associated With High Dose Marihuana Smoking
Effects of Cannabinoids On Reproductive Organs in the Female Fischer Rat
Effect of Delta-9-Tetrahydrocannabinol (Thc) On Female Reproductive Function
The Effect of A Crude Marihuana Extract On Embryonic and Foetal Development of the Rabbit
Effects of Cannabis On Fetal Development of Rodents
Reproduction in Rhesus Monkeys Chronically Exposed to Delta-9-THC
Summary of Session III
IV. Cannabis and The Brain
Ultrastructural and Biochemical Changes in Cns Induced by Marihuana
Brain Biochemical Alterations in Neonates of Dams Treated Orally Withdelta
Cannabis and The Brain With Special Reference to The Limbic System
Cannabis and Brain-Stimulation Reward
Cannabis and The Development of Tolerance
Pharmacological Similarities and Interactions Between Cannabis and Opioids
Delta-9-Tetrahydrocannabinol and the Quasi-Morphine Withdrawal Syndrome
Cannabis and Epilepsy
Marihuana and Epilepsy: Paradoxical Anticonvulsant and Convulsant Effects
Effects of Cannabis On Human EEGn
Effects of Marihuana On Pain and Verbal Memory: A Sensory Decision Theory Analysis
Residual Effects of High-Dose Cannabis Treatment On Learning, Muricidal Behavior ad Neurophysiological Correlates in Rats
Social Behavior of Rhesus Monkeys Chronically Exposed to Moderate Amounts of Delta-9-Tetrahydrocannabinol
Chronic Marihuana Smoking: Its Effect On Function and Structure of the Primate Brain
Summary of Session IV
Concluding Summary
Appendix—Cannabis and Alcohol: The Green and The Red
Author Index
Subject Index
- Edition: 1
- Latest edition
- Published: October 30, 1979
- Language: English
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