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Essays in Toxicology
Volume 5
1st Edition - January 1, 1974
Editor: Wayland J. Hayes
eBook ISBN:9781483216454
9 7 8 - 1 - 4 8 3 2 - 1 6 4 5 - 4
Essays in Toxicology, Volume 5 covers essays in toxicology. The book presents essays on nitrosamines; a laboratory model ecosystem to evaluate compounds producing biological… Read more
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Essays in Toxicology, Volume 5 covers essays in toxicology. The book presents essays on nitrosamines; a laboratory model ecosystem to evaluate compounds producing biological magnification; and the metabolism of DDT in human. The text also includes essays on the toxins of Clostridium botulinum; the use of breath analysis in clinical toxicology; and the biochemical toxicology of methanol. Toxicologists, biochemists, microbiologists, pharmacologists, and people involved in the research of toxicology will find the book invaluable.
List of Contributors
Preface
Contents of Previous Volumes
1. Nitrosamines
I. Introduction
II. Discovery of the Carcinogenic Effects of Nitrosamines
III. What May Be Learned from Study of Nitrosamines
References
2. A Laboratory Model Ecosystem to Evaluate Compounds Producing Biological Magnification
I. Introduction
II. Development of a Laboratory System for Evaluation of Micropollutants
III. Problems Investigated
References
3. The Metabolism of DDT in Man
I. Background and Rationale of the Present Study of DDT Metabolism in Man
II. Subjects, Materials, and Methods
III. Absorption and Storage of Ingested DDT
IV. Chemical Conversions of Ingested DDT and DDT Metabolites
V. Relation of Blood Concentrations of DDT Isomers and Metabolites to the Adipose Stores of These Chemicals
VI. Loss of Fat-Stored DDT and DDT Metabolites
VII. Summary and Commentary
References
4. The Toxins of Clostridium botulinum
I. Introduction
II. Nature and Distribution of Clostridium botulinum
III. Toxin Production
IV. Qualitative and Quantitative Assays for Botulinum Toxins
V. Purification and Properties of the Toxins
VI. Studies on the Relation of Functional Groups to Toxicity
VII. Mechanism of Action of the Toxins
VIII. Diagnosis, Treatment, and Prevention of Botulism
References
5. The Use of Breath Analysis in Clinical Toxicology