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Elsevier

Books in Life sciences

  • Alcohol and Abnormal Protein Biosynthesis

    Biochemical and Clinical
    • 1st Edition
    • Marcus A. Rothschild + 2 more
    • English
    Alcohol and Abnormal Protein Biosynthesis: Biochemical and Clinical focuses on the methods for measuring protein metabolism and the effects of alcohol and altered protein intake as they affect the heart, liver, skeletal muscle, and the brain. Organized into six sections, this book begins with an overview on malnutrition and alcoholism, as well as available techniques for the study of protein synthesis. Subsequent section details the adaptation of protein synthesis and transport to alcohol and malnutrition. Section three discusses the skeletal and cardiac muscle protein metabolism. The last three sections describe the reaction of hepatic protein synthesis to malnutrition and alcohol; effects of alcohol on brain RNA metabolism; and alcohol associated cardiac and hepatic disease.

  • Biologically Active Amines Found in Man

    Their Biochemistry, Pharmacology, and Pathophysiological Importance
    • 1st Edition
    • Franz Franzen + 1 more
    • English
    Biologically Active Amines Found in Man: Their Biochemistry, Pharmacology, and Pathophysiological Importance deals with the biochemistry, pharmacology, and pathophysiology of biologically active amines present in the human body. Emphasis is placed on amines derived by decarboxylation of α-amino acids in human beings and some of their especially interesting metabolites. This book consists of four chapters and opens with an overview of biogenic amines and their origin, followed by a discussion on their biochemistry, pharmacology, and pathophysiology. The metabolism and inactivation of biologically active amines such as tyramine, dopamine, noradrenaline, adrenaline, tryptamine, serotonin, and histamine are examined, along with their incorporation into the body protein and their rate of turnover. The influence of biologically active amines on the function of the kidneys, microcirculation, and respiratory metabolism is also considered. Finally, illnesses in which indigenous amines have known or possible/probable pathophysiological significance are described. This monograph will be of interest to biologists, biochemists, pharmacologists, and pathophysiologists.

  • Protides of the Biological Fluids

    Proceedings of the Twentieth Colloquium, Brugge, 1972
    • 1st Edition
    • H. Peeters
    • English
    Protides of the Biological Fluids: Twentieth Volume is a collection of studies about three selected topics from the general field of protein chemistry. The book is divided into four sections. Section A covers monoclonal immunoglobulins and its properties and structure; the amyloid substance; and antibody function. Section B covers active polypeptides derived from plasma proteins; the kinin system; the angiotensin and renin system; anaphylatoxins; and protease inhibitors. Section C covers microcalorimetry in biological systems; biological system and its relation with thermodynamics; and the application of microcalorimetry to biological systems. The book also includes a Section D, which does not consider any of the selected topics, but instead focuses on other techniques such as the double line method; radioimmunoassay of alpha-fetoprotein; and the IgM latex test. The text is recommended for students and reseearchers in the fields of biology, biochemistry, and other related fields, especially those who wish to learn more about monoclonal immunoglobulins, fibrinopeptides, and the effect of microcalorimetry in biological systems.

  • Advances in the Biosciences

    International Conference on Prostaglandins, Vienna, September 25 to 28, 1972
    • 1st Edition
    • Stig M. Bergström
    • English
    Advances in the Biosciences 9 is a collection of presented papers on the International Conference on Prostaglandins, held in Vienna, Austria on September 25 to 28, 1972. The book consists of 114 chapters of various topics in the field of prostaglandins. The meeting touches on several main topics such as new active analogs of prostaglandins; effect of aspirin and indomethasin and other compounds relative to the study of the role of the prostaglandins in the living organism; and the evaluation of the various analytical methods for the determination of the extremely minute amounts of prostaglandin occurring in the living organism. Biologists, pharmacologists, endocrinologists, physicians, biochemists, and medical technologists will find the contents of this book invaluable.

  • Modelling and Control of Biotechnological Processes

    Proceedings of the 1st IFAC Symposium, Noordwijkerhout, The Netherlands, 11 – 13 December 1985
    • 1st Edition
    • A. Johnson
    • English
    Modelling and Control of Biotechnological Processes contains the proceedings of the International Federation of Automatic Control's First Symposium on Modeling and Control of Biotechnological Processes held in Noordwijkerhout, The Netherlands, on December 11-13, 1985. The papers explore modeling and control of biotechnological processes such as fermentation and biological wastewater treatment. This book consists of 37 chapters divided into 11 sections and begins with a discussion on the control of fermentation processes; modeling of biotechnical processes; and application of measurement and estimation techniques to biotechnology. The following sections focus on adaptive control theory, applications of adaptive control, and control and modeling of bioreactors. The reader is also introduced to measurement techniques and sensors, with emphasis on pyrolysis mass spectrometry; rapid bioelectrochemical methods; and a self-tuning controller for multiloop controlled fed-batch fermentation. The remaining sections deal with parameter identification and estimation; Kalman filtering techniques; optimization of production processes; modeling of microkinetics; and optimization theory. This monograph will be of interest to researchers and practitioners in the field of biotechnology.

  • Acetylcholine

    An Approach to the Molecular Mechanism of Action
    • 1st Edition
    • M. J. Michelson + 1 more
    • P. Alexander + 1 more
    • English
    Acetylcholine: An Approach to the Molecular Mechanism of Action is an in-depth study of neurotransmitter system, with much focus on acetylcholine and its action and the cholinergic synapse. The book, divided into seven chapters, covers the following topics: the function of the cholinergic synapse; the movement of ions across membranes; the excitatory postsynaptic potential; the nature of cholinoreceptors and cholinesterases; the structure of its active centers; and the pattern of arrangement of the receptors of the cholinoreceptive membrane. The book also covers the quantitative evaluation of the action of neurotransmitters; the reactive capacity of the acetylcholine molecule and its effects on nerve endings and nerve fibers; and the release of mediators and hormones. The text is recommended for those who specialize in the fields of biology, medicine, biochemistry, and pharmacology, especially those wish to study about the neurotransmitter system, cholinoreceptors, the cholinergic synapse, the acetylcholine, and its action.

  • Structure and Function of Oxidation–Reduction Enzymes

    Proceedings of the Wenner-Gren Symposium Held at the Wenner-Gren Center, Stockholm, 23–27 August, 1970
    • 1st Edition
    • Ã…. Ã…keson + 1 more
    • English
    Structure and Function of Oxidation–Reduction Enzymes is a collection of papers presented at the Wenner-Gren Symposium held at the Wenner-Gren Center, Stockholm on August 23-27, 1970. It provides important understanding of the structure and function of oxidation-reduction enzymes: iron, flavin, and nicotinamide enzymes. This book discusses the functional differences among varying structures such cytochrome c, haemoglobins, dehydrogenases, flavins, oestrogens, and peroxidases. It concludes by presenting future expectations, including some questions that need to be addressed. This volume will be of great value to those interested in the present-day research on oxidation-reduction enzymes.

  • Immunological Surveillance

    • 1st Edition
    • Macfarlane Burnet
    • English

  • Alligator Metabolism Studies on Chemical Reactions in Vivo

    • 1st Edition
    • Roland A. Coulson + 1 more
    • English
    Alligator Metabolism: Studies on Chemical Reactions in Vivo presents a summary of research in vivo on the metabolism of alligators. The volume contains updates of earlier investigations which were presented in Biochemistry of the Alligator, a Study of Metabolism in Slow Motion (1964). Since then, with the aid of better equipment and better methods, it seemed time to correlate and summarize the findings of researchers who have used this remarkable experimental animal with profit. The primary purpose of almost all the research was not to determine the nature of the alligator, but to understand biochemical reactions in vivo and the alligator was a means to that end. The book begins with a chapter on natural history for those scientists, wild-life experts, alligator farmers, zoo keepers etc., whose primary interest is in the nature and habits of the intact alligator. This is followed by separate chapters that deal with metabolic rate, anaerobic glycolysis, digestion-growth-pro... synthesis, carbohydrate metabolism, amino acid metabolism, respiration and acid-base balance, and kidney function.

  • Assay of Protein and Polypeptide Hormones

    International Series of Monographs in Pure and Applied Biology Modern Trends in Physiological Sciences
    • 1st Edition
    • H. Van Cauwenberge + 1 more
    • P. Alexander + 1 more
    • English
    International Series of Monographs in Pure and Applied Biology, Modern Trends in Physiological Sciences, Volume 33: Assay of Protein and Polypeptide Hormones focuses on the assays of protein and polypeptide hormones. The selection first discusses the general principles of protein and polypeptide hormone assays, including conditions and basic factors for bioassays and status of biological assays. The book looks at the assays of hypophyseal hormones, such as growth hormones, adrenocorticotropin (ACTH), thyrotropin, gonadotropins, prolactin, vasopressin, and oxytocin. Concerns include radioimmunoassay, standards of thyrotropin, immunoassay of hypophyseal gonadotropins, and bioassay of prolactin. The book evaluates the assays of pancreatic hormones, such as insulin and glucagon. Chemical structure and properties of insulin and radioimmunoassay of glucagon are explained. The text also focuses on the assays of erythropoietin, renin, human chorionic gonadotropin, and human placental lactogen (HPL). Concerns include augmentation of red cell volume; biological application of renin assays; and similarities and differences between hypophyseal somatotropin and HPL. The selection is a valuable source of data for readers interested in the assays of protein and polypeptide hormones.

  • The Biochemistry of Development

    International Series of Monographs on Pure and Applied Biology
    • 1st Edition
    • Jean Brachet
    • P. Alexander + 1 more
    • English
    The Biochemistry of Development focuses on advances in chemical embryology. The book first discusses gametogenesis, including the processes of oogenesis and spermatogenesis. The text describes fertilization and related aspects, such as physical, morphological, and metabolic changes during fertilization. The selection also underscores the process of cleavage. Concerns include morphology and cytochemistry of dividing eggs; importance of nucleic acids and proteins; formation of the furrow; and biochemistry of cleavage. The text also looks at the chemical embryology of invertebrate eggs. Examinations are done on the eggs of worms, mollusks, sea urchins, and ascidians. The book also evaluates the chemical embryology of vertebrate eggs. RNA and protein metabolism of intact eggs; chemical nature of inducing substances; and physical properties of inducing agents are underscored. The text also offers information on the biochemistry of differentiation and the biochemical interactions between the nucleus and the cytoplasm during morphogenesis. The selection is highly recommended for readers wanting to study chemical embryology.

  • A Laboratory Manual of Analytical Methods of Protein Chemistry

    • 1st Edition
    • P. Alexander + 1 more
    • English
    A Laboratory Manual of Analytical Methods of Protein Chemistry, Volume 5 presents the laboratory techniques for protein and polypeptide study. This book discusses the staining procedure for histones, which has a high degree of selectivity for basic proteins and the unique ability to visualize qualitative differences in terms of color changes. Organized into four chapters, this volume begins with an overview of the formalin-mediated ammoniacal-silver staining procedure as a selective stain for basic proteins and its application per cell and per extract. This text then examines the optical rotatory dispersion (ORD), which has advanced into a powerful tool for describing the conformations and conformational changes of biopolymers. Other chapters consider the application of ultrasensitive calorimetry to thermodynamic problems. This book discusses as well the principle of the technique, its instrumentation, and experimental procedures. The final chapter deals with the hydrodynamic densities and preferential hydration values for protein precipitates in concentrated salt solutions. This book is a valuable resource for chemists and biochemists.

  • International Congress for Microbiology

    Moscow, 1966
    • 1st Edition
    • Sam Stuart
    • English
    IX International Congress for Microbiology discusses the genetic regulation of microbial metabolism. This book presents the recommendations and suggestions on the nomenclature and classification of viruses. Organized into eight parts encompassing 72 chapters, this compilation of papers starts with an overview of the genetic code, which expresses the relationship between nucleotide triplets in messenger RNA and amino acids in proteins. This text then discusses the two aspects of the regulation of the physiology of Escherichia coli. Other chapters explore the ergot alkaloids and examine the problem of ergot alkaloid production and biosynthesis. This book discusses as well the antibiotic inhibitors of protein synthesis that are major clinical drugs, including chloramphenicol, tetracycline, streptomycin, erythromycin, and other aminoglycosides. The final chapter deals with karyological investigation of the cells during transformation by Rous virus (RSV), which shows that these cells retain a diploid character. This book is a valuable resource for epidemiologists, microbiologists, and experts in infectious diseases.

  • Amines and Schizophrenia

    • 1st Edition
    • Harold E. Himwich + 2 more
    • English
    Amines and Schizophrenia is a collection of articles that survey and discuss the biochemical basis present, if any, in schizophrenia, focusing on the role of certain amines. The book discusses certain hypotheses dealing with the field of bio-chemistry as the basis for diseases such as schizophrenia, manic-depressive psychosis, and related diseases. Discussions start with the properties of mescaline, because the psychotic effect of the drug has some aspects similar to that of a schizophrenic syndrome. One paper examines the presence of certain amines, such as norepinephrine, dopamine, and serotonin in the brain, including their role in the synaptic transmission of nerve impulses in the central nervous system. Other papers review the role of derangements of tryptophan metabolism in psychotic behavior; the metabolic interrelationships of tryptophan and methionine in mental illness; and the results obtained with psychomimetic and non-psychomimetic congeners of three classes of indoleamines including LSD. The book gives more details on the actions of various biological amines on single neurons in the limbic system of the brain. The text also evaluates the use of hallucinogenic drugs in considering their heuristic value in the study of the biochemical basis of mental function. The selection will prove relevant for psychologists, psychiatrists, drug researchers, pharmacologists, and chemical laboratory workers and technicians.

  • Vaccines

    New Approaches to Immunological Problems
    • 1st Edition
    • Ronald W. Ellis
    • English
    Vaccines: New Approaches to Immunological Problems presents the advances in the range of strategies and approaches for producing vaccines. The book is comprised of 20 chapters that cover the properties of different vaccines. The coverage of the text includes vaccines for cholera, malaria, helminth, and influenza. The book also discusses topics about the key elements of modern technologies that can be applied to different vaccines, such as active immunization strategies using anti-idiotypic antibodies; passive immunoprophylaxis with human monoclonal antibodies; and immunological adjuvants and their mode of action. The text will be of great use to scientists involved in the research and development of vaccines, such as molecular biologists, biochemists, and virologists.

  • Histochemistry

    An Explanatory Outline of Histochemistry and Biophysical Staining
    • 1st Edition
    • Richard W. Horobin
    • English
    Histochemistry: An Explanatory Outline of Histochemistry and Biophysical Staining describes the histochemical staining of cells and tissues as a major tool applied in biological and medical investigations, both in basic research and in practical applications such as clinical diagnosis. The book may be considered as a guide to understanding the scientific basis of staining procedures and alternate actions to take when common methods do not proceed as expected. The first chapter gives general theoretical ideas from which most part of the book is largely organized around. As the book considers the arts and crafts making up the practice of histochemistry and biological staining, emphasis is given to the common physicochemical aspects of the technically diverse methodologies involved. Hence, the author has drawn ideas and information from physicochemically and biochemically related fields, such as chromatography, pharmacology, photography, tanning, and textile dyeing. The bulk of the book is structured around groups of practical procedures, such as fixation, staining with dyestuffs, metal impregnation, and selective extraction as a test of significance. Lastly, general essays on the usefulness of staining theories and on the problems arising from reagent impurities are given as examples. The text is suitable for students and researchers in the fields of physiology, biochemistry, and pharmacology. Clinical laboratory scientists and those involved in the life sciences and biotechnology will benefit from reading the book.

  • Urea as a Protein Supplement

    • 1st Edition
    • Michael H. Briggs
    • English
    Urea as a Protein Supplement presents the significant advances that have been made in ruminant nutrition. This book examines the role of the rumen flora and fauna as synthesizers of protein from non-protein nitrogen sources such as ammonium compounds and urea. Organized into four parts encompassing 23 chapters, this book starts with an overview of the use of urea and other non-protein nitrogen sources in ruminant nutrition. This text then explores the various methods that may be used for the preparation of urea, which involves the dehydration of ammonium carbamate produced by the reaction of carbon dioxide and ammonia at high pressure and temperature. Other chapters consider the ways in which urea could be utilized to increase protein supplies. The final chapter deals with the hydrolysis of urea by urease to ammonia and carbon dioxide, which has been used as a method for determining urea for many years. Agricultural scientists and farmers will find this book useful.

  • Enzyme Chemistry of Phenolic Compounds

    Proceedings of the Plant Phenolics Group Symposium, Liverpool, April 1962
    • 1st Edition
    • J. B. Pridham
    • English
    Enzyme Chemistry of Phenolic Compounds documents the proceedings of the Plant Phenolics Group Symposium held at Liverpool on April 11-12 1962. This book focuses on the interaction of enzymes and phenolic compounds, oxidation-reduction systems in plants and microorganisms, and phenolase complex. Other topics discussed include purification of phenol oxidases; enzyme-substrate specificity in potato polyphenol oxidase; tocopherols; and role of ubiquinone and plastoquinone in plant metabolism. Hydrolytic enzymes; enzyme inhibition by phenolic compounds; tannin inhibition of plant mitochondria; and aromatic acid-reducing systems in fungi are also deliberated in this selection. This publication is beneficial to students and biochemists researching on enzyme and phenolic compounds.

  • Proceedings of the Fifth International Seaweed Symposium, Halifax, August 25–28, 1965

    • 1st Edition
    • E. Gordon Young + 1 more
    • English

  • The Biochemistry of Poliomyelitis Viruses

    A Synopsis of Poliomyelitis Infection and Research
    • 1st Edition
    • Ernest Kovács
    • P. Alexander + 1 more
    • English
    The Biochemistry of Poliomyelitis Viruses deals with the interrelationships and differences of positions in the field of poliomyelitis research. This volume presents a general introduction to viruses as to their descriptions and biological, biochemical, and epidemiological aspects. Clinical poliomyelitis, test measurements in the cerebrospinal fluid, and the actions of the poliomyelitis virus are explained. The isolation of the poliomyelitis virus and some aspects of its immunology and serology through refinements of serologic tools and special techniques, plus the state of poliovirus purification, are noted. This book also gives assumptions about the virus' synthetic activities in vivo based on experiments conducted in other viral diseases other than the polio virus. This text also notes that important discoveries such as those made by Gierer and Schramm or Fraenkel-Conrat provide updated poliomyelitis research. Other research studies are taken into consideration and emphasis is given to the biochemical concept of the polio infection and the related features induced during infection such as the presence of tumors. The most promising trend in research is in the study of enzymes of infected cells leading to an understanding of the biochemistry of viral diseases. The use of inference microscopy and X-ray analysis of cell mass is recommended. This book will prove invaluable for microbiologists, disease investigators, clinical workers, and research scientists.

  • Mechanisms of Release of Biogenic Amines

    Proceedings of an International Wenner-Gren Center Symposium Held in Stockholm, February 1965
    • 1st Edition
    • U. S. Von Euler + 2 more
    • English
    Wenner-Gren Center International Symposium Series, Volume 5: Mechanisms of Release of Biogenic Amines provides information pertinent to the fundamental aspects of the release of biogenic amines. This book discusses the physiology, biochemistry, and pharmacology of the biogenic amines. Organized into 39 chapters, this volume begins with an overview of the release of amines, which is implicated in functional disturbances characteristic of different diseases. This text then examines the concepts of cell structure that are significant to the release of neurohumoral agents. Other chapters consider the fluorescence reaction, which made it possible to work out a practical histochemical procedure. This book describes as well a few examples in which the monoaminergic transmitter is not revealed as a diffuse cytoplasmic fluorescence. The final chapter deals with acetylcholine as the only brain amine investigated, which could be influenced by the tremorgenic agents during the period of tremor. This book is a valuable resource for biochemists, morphologists, pharmacologists, and physiologists.

  • The Provision and Use of Library and Documentation Services

    Some Contributions from the University of Sheffield Postgraduate School of Librarianship
    • 1st Edition
    • W. L. Saunders
    • English
    The Provision and Use of Library and Documentation Services is a collection of papers that deals with library interdependent considerations of use and service. One paper discusses the value, organization, and exploitation of trade literature, citing the importance of maintaining a file of trade catalogues to narrow the gap between industrial activity and academic research. Another paper reports a high library membership (80% - 100%) on a survey of library provision and services in four correctional institutions in London. The author notes that professional advice should also be available to help the prisoner read effectively. One author reviews the library services for undergraduates particularly problems of inadequate services and facilities. Other authors discuss the pattern of borrowing in several libraries which generalizes the borrowing behavior of academic communities, such as the rising levels of foreign language and "off-subject" borrowing. Of interest is one author's analysis of the way scientists use libraries in terms of finding information, reading, and use of facilities. His conclusion: scientists have no clear-cut opinion on the best method of acquiring information. This book is suitable for librarians, administrators of private or public library systems, for students and academicians in the field of library science.

  • Proceedings of the First International Congress of Parasitology

    Roma, 21-26 September 1964
    • 1st Edition
    • Augusto Corradetti
    • English

  • Cell Biology of the B Cell Receptor

    • 1st Edition
    • Volume 123
    • Hidde Ploegh
    • English
    Advances in Immunology, a long-established and highly respected publication, presents current developments as well as comprehensive reviews in immunology. Articles address the wide range of topics that comprise immunology, including molecular and cellular activation mechanisms, phylogeny and molecular evolution, and clinical modalities. Edited and authored by the foremost scientists in the field, each volume provides up-to-date information and directions for the future.

  • Brucellosis

    • 1st Edition
    • M. Monir Madkour
    • English
    Brucellosis presents an overview of the conditions associated with the subject matter. It discusses the disease of protean manifestations affecting all types of tissues and organs in the body. It addresses the different facet of the disease studied in isolation. Brucellosis is a zoonotic disease common around the world. Some of the topics covered in the book are the historical origin of different species of Brucella strain; epidemiological features of brucellosis; occupational hazards of working in the meat processing environment; identification and taxonomy of bacteria carrying the Brucella strain; and methods for the identification of cultures. The pathology and immunology of brucellosis in humans are fully covered. The histopathological aspects of the brucella organisms are discussed in detail. The text describes in depth the cardiovascular complications of the disease. The diagnosis of brucella thrombophlebitis is completely presented. A chapter is devoted to the respiratory and gastrointestinal manifestations of brucella organisms. The book can provide useful information to veterinarians, doctors, chemists, students, and researchers.

  • The Separation and Isolation of Proteins

    a Laboratory Manual of Analytical Methods of Protein Chemistry (Including Polypeptides)
    • 1st Edition
    • P. Alexander + 1 more
    • English
    A Laboratory Manual of Analytical Methods of Protein Chemistry (Including Polypeptides), Volume 1: The Separation and Isolation of Proteins deals with the techniques used in the separation and isolation of proteins, including fractionation and characterization by dialysis, multi-membrane electrodecantation, and zonal density gradient electrophoresis. The fractionation of proteins by adsorption and ion exchange is also described. This book is comprised of seven chapters and begins with a discussion on procedures for the separation of proteins, paying particular attention to the liberation of proteins from cellular material; removal of lipids from lipoproteins; and denaturation, fractionation, and purification of proteins. The next chapter focuses on the isolation of biologically active proteins such as cytochrome, bacterial amylases, and bacterial proteinases. The reader is methodically introduced to fractionation of proteins by adsorption and ion exchange; fractionation and characterization by dialysis; multi-membrane electrodecantation; and continuous and discontinuous partition. The final chapter explains how zonal density gradient electrophoresis works as a separation method for natural mixtures of proteins, their degradation products, and other substances carrying electric charges in solution or suspension. This volume will be of interest to chemists working with proteins.

  • The Evolution of the Microscope

    • 1st Edition
    • S. Bradbury
    • English
    The Evolution of the Microscope covers some of the features of the history of the microscope and the rationale of the design features found in microscopes. The book discusses the first microscopes, the compound microscope in England (1650-1750), simple or single-lens microscopes, and the development of the achromatic microscope. The text also describes the microscope in Victorian times as well as the optical microscope since 1880. The search for greater resolving power such as the ultra-violet and electron microscopes is considered. Scientists and microscopists will find the book invaluable.

  • Postharvest Decay

    Control Strategies
    • 1st Edition
    • Silvia Bautista-Baños
    • English
    Written by a diverse group of research professionals, Postharvest Decay: Control Strategies is aimed at a wide audience, including researchers involved in the study of postharvest handling of agricultural commodities, and undergraduate and graduate students researching postharvest topics. Growers, managers, and operators working at packinghouses and storage, retail, and wholesale facilities can also benefit from this book. The information in this book covers a wide range of topics related to selected fungi, such as taxonomy, infection processes, economic importance, causes of infection, the influence of pre-harvest agronomic practices and the environment, the effect of handling operations, and the strategic controls for each host-pathogen, including traditional and non-traditional alternatives.

  • Emerging Infectious Diseases

    Clinical Case Studies
    • 1st Edition
    • Volume 1
    • Onder Ergonul + 3 more
    • English
    More than 30 newly emerged microorganisms and related diseases have been discovered in the past 20 years. Since these infections are so new, even infectious diseases experts and clinical microbiologists need more information. This book covers recently emerged infectious diseases based on real cases and provides comprehensive information including different aspects of the infections. Written in a ‘teaching’ style, this book is of interest to every medical specialist and student.

  • Immunology in Clinical Medicine

    • 3rd Edition
    • J. L. Turk
    • English
    Immunology in Clinical Medicine is an introduction to immunology in clinical medicine, with emphasis on immunological concepts underlying disease processes. The effect of drugs known to suppress immunological processes are considered especially in relation to whether they operate by really suppressing immunological processes or whether they have other actions. Comprised of 17 chapters, this book begins with an overview of the nature of the immune response, followed by a discussion on reactionS in the tissues mediated by humoral antibodies. The reader is then introduced to reactions in the tissues caused by the cell-mediated immune response; immunological processes in infective diseases; and the concept of autoimmunity and its relation to disease. Subsequent chapters focus on the immunology of diseases such as cancer, skin diseases, connective tissue diseases, and diseases of the intestinal tract, respiratory tract, liver, and amyloidosis. The final chapter is devoted to the role of the clinical immunologist in patient care and therapy. This monograph is intended for students and practitioners of clinical medicine.

  • Essentials of ABO -Rh Grouping and Compatibility Testing

    Theoretical Aspects and Practical Application
    • 1st Edition
    • W. John Lockyer
    • English
    Essentials of ABO-Rh Grouping and Compatibility Testing: Theoretical Aspects and Practical Application focuses on overall safety in blood transfusion, including accurate ABO and Rh-D grouping of both patient and donor. The book first elaborates on the ABO blood group system and the Rh blood group system and hemolytic disease of the newborn. Discussions focus on the Rh-D antigen, Rh genotyping, Rh testing of blood donors and recipients of blood, antenatal and postnatal serology in cases other than Rh and ABO hemolytic disease, selection and preparation of Rh anti-D grouping reagent, dangerous group O donor blood, alternative sources of anti-A and anti-B blood grouping reagent, and development of the A and B red cell antigens. The manuscript then takes a look at compatibility testing (crossmatching) and transfusion reaction investigations, as well as compatibility testing and preparation of blood for patients with antibodies to serum proteins; compatibility testing of patients with known irregular antibodies; non-urgent compatibility testing of blood; and compatibility testing for patients requiring platelets. The publication takes a look at practical procedures, including grades of agglutination, control of anti-human globulin serum, preparation of low ionic strength saline, and preparation of platelet concentrates. The text is a valuable source of information for researchers interested in ABO-Rh grouping and compatibility testing.

  • Bacteriology for Nurses

    • 2nd Edition
    • Geoffrey A. Taylor
    • English
    Bacteriology for Nurses provide nurses and others who are associated with medicine with a simple outline of basic bacteriology and the applications of bacteriology to medicine and to nursing. The fundamentals of medical bacteriology, namely the anatomy and physiology of bacteria, infection, and the body defenses against infection are discussed. The bacteria which cause common diseases of various sites in the body, such as the respiratory tract and the gastrointestinal tract, are considered together. Only common and important infections are included. Comprised of 15 chapters, this book begins with a historical background on bacteriology, followed by a discussion on the biology of bacteria. A classification of bacteria is then presented, and infections caused by bacteria are described. Subsequent chapters focus on body defenses against bacterial infections; rickettsiae and viruses; pyogenic and chronic bacterial infections; and collection of bacteriological specimens as part of bacteriological diagnosis. Infections of the respiratory tract, gastrointestinal tract, and the nervous system are also analyzed. The final chapter is devoted to elementary parasitology. This monograph will be of interest to nurses as well as immunologists, bacteriologists, pathologists, physiologists, clinicians, and research workers in the field of medicine.

  • Human Chromosomes

    An Illustrated Introduction to Human Cytogenetics
    • 1st Edition
    • Audrey Bishop + 1 more
    • English
    Human Chromosomes: An Illustrated Introduction to Human Cytogenetics focuses on the processes, methodologies, and approaches involved in the study of human chromosomes. The publication first offers information on the cell and its activity, particularly noting that the cell is the basic unit that forms the organs and tissues of the human body. The differentiation of cells and the process of cell division are discussed. The text then focuses on the culture of human cells for the investigation of the chromosomes. The book elaborates on the identification of human chromosomes, including further methods of identification and the use of radioactive isotopes. The publication also ponders on the numerical changes in the karyotype, structural changes, and X chromosomes. Discussions focus on the processes of mitosis and meiosis, translocation, deletion, duplication, and ring formation, and the behavior, transformation, and characteristics of X chromosome. The text is a valuable reference for researchers interested in the study of human chromosomes.

  • MCQ Tutor for Students of Microbiology

    • 1st Edition
    • John Gordon
    • English
    MCQ Tutor for Students of Microbiology provides a series of multiple choice questions with annotated answers, mainly in bacteriology but also including parasitology, virology, and immunology. This book focuses on clinical applications. Organized into four parts, this book begins with an overview of the pre-clinical aspects of microbiology and host defense mechanisms. This text then deals with microbial systematics as well as the detailed properties of the various microorganisms. Other parts cover the nature and manifestation of a wide spectrum of infective diseases. This book discusses as well the laboratory diagnosis, treatment, and prevention of infective diseases. The final part deals with other examples of other forms of multiple choice question. This book is intended to be suitable for medical students in the second and third undergraduate years as an aid to preparation for their third MB examination. Students of medical and laboratory sciences as well as candidates for diploma and college examinations will also find this book useful.

  • The Alkaloids

    Chemistry and Physiology
    • 1st Edition
    • R. H. F. Manske + 1 more
    • English
    The Alkaloids: Chemistry and Physiology, Volume IV contains an account of the chemistry and biosynthesis of the various classes of isoquinolines. This book discusses the extraction and separation of the anhalonium alkaloids, other natural simple isoquinolines, and anhalonium isoquinolines. The location of the alkaloids in tissues of the cacti, monophenolic bases of the laudanosine type, and extraction of cactus alkaloids are elaborated in detail. This text also describes the several types of alkaloids such as protoberberine, aporphine, protopine, phthalideisoquinolin... and bisbenzylisoquinolin... The cularine, a-naphthaphenanthrid... erythrophleum, aconitum, and delphinium alkaloids are likewise included. This publication is recommended for chemists, specialists, and students interested in isoquinolines.

  • Amino Acids, Proteins and Cancer Biochemistry

    • 1st Edition
    • Jesse P. Greenstein
    • John T. Edsall
    • English
    Amino Acids, Proteins, and Cancer Biochemistry focuses on the contributions of Jesse P. Greenstein to biological chemistry, including kinetics, protein mixtures, metabolism, tumors, and biosynthesis. The selection first offers information on quantitative nutritional and in vivo metabolic studies with water-soluble, chemically defined diets and internal hydrogen bonding in ribonuclease. Discussions focus on the effects of deuterium on transition temperature, kinetics of deuterium-hydrogen exchange, applications of chemically denned diets, formulation of water-soluble, chemically defined diets, and large-scale preparation of optically pure amino acids. The manuscript then examines the chromatographic evaluation of protein mixtures and observations on the activation of amino acids and biosynthesis of peptide bonds, including synthesis of phenylacetylglutamin... and benzoylglycine, studies on amino acyl adenylates, and synthesis of glutamine. The publication ponders on free amino acids and related substances in normal and neoplastic tissues; nucleic acids of normal tissues and tumors; and carbohydrate metabolism in ascites tumor and HeLa cells. Topics include carbohydrate metabolism of ascites tumor cells, comparative biochemistry of glycolysis, DNA and the genetic concept of cancer, and constancy of free amino acid patterns of tissues. The selection is a valuable source of data for biochemists and researchers interested in amino acids, proteins, and cancer biochemistry.

  • An Introduction to Biochemistry

    • 2nd Edition
    • William Robert Fearon
    • English
    An Introduction to Biochemistry, Second Edition provides information pertinent to the fundamental aspects of biochemistry. This book presents several analytical methods, including the citrulline reaction for proteins and the diffusion test for acetone. Organized into two parts encompassing 25 chapters, this edition begins with an overview of the general composition of the organism and the chemical characteristics of the chief organic and inorganic compounds that enter into its structure. This text then examines the chemical composition of the tissues and physiological systems. Other chapters consider the occurrence and identification of several pathological constituents of urine, which presents features of biochemical interest. This book discusses as well the significance and analytical reactions of the bile acids and esters. The final chapter deals with the internal environment, which in the higher animal is represented by the blood and the cerebrospinal and other tissue fluids. This book is a valuable resource for biochemists.

  • Biophysical Chemistry

    Thermodynamics, Electrostatics, and the Biological Significance of the Properties of Matter
    • 1st Edition
    • John T. Edsall + 1 more
    • English
    Biophysical Chemistry, Volume I: Thermodynamics, Electrostatics, and the Biological Significance of the Properties of Matter focuses on the biological aspects of the properties of matter, putting emphasis on the chemical elements, water and carbon dioxide, complex molecules, and proteins. The publication first elaborates on biochemistry and geochemistry, water and its biological significance, and the problems of protein structure. Discussions focus on the number of peptide chains in the molecule and nature of terminal groups, latent heat of fusion, characteristics of the amino acids derived from proteins, expansion of water in freezing, and the relative abundance of chemical elements in the universe. The text then takes a look at thermodynamics and the application to polar molecules and ionic solutions of electrostatics, including free energy of a charged sphere, image charges, salting-out effect, expressions for the change of fundamental thermodynamic functions, and chemical potentials. The book examines the conductivity of electrolytes, acid-base equilibria, and polybasic acids, bases, and ampholytes, including proteins. Topics include ionization of cysteine, isoelectric points of polyvalent ampholytes, hemoglobin, nature of acids and bases, measurement of conductivity, electrolytes as conductors, and the moving boundary method of determining transference numbers. The manuscript is a dependable reference for chemists and researchers interested in thermodynamics, electrostatics, and the biological value of the properties of matter.

  • Polysaccharides Peptides and Proteins

    Pharmaceutical Monographs
    • 1st Edition
    • R. T. Coutts + 1 more
    • J. B. Stenlake
    • English
    Pharmaceutical Monographs, Volume 4: Polysaccharides Peptides and Proteins provides information pertinent to a wide variety of naturally-occurring macromolecules that are either peptide, protein, or polysaccharide in nature, which are important as medicinal and pharmaceutical agents. This monograph presents the basic physical and chemical properties of polysaccharides. Organized into four chapters, this volume begins with an overview of the pharmaceutical importance of the class of compounds known as polysaccharides. This text then provides data on the structure of the polysaccharides that is obtained by isolating and identifying the product formed on hydrolysis of the molecule itself. Other chapters consider plant gums and mucilages as important medicinal and pharmaceutical products. This monograph discusses as well the autohydrolysis of gum arabic. The final chapter deals with the clinical applications of various peptide-type antibiotics. This monograph is a valuable resource for undergraduate students of pharmacy and allied subjects.

  • The Kidney

    Morphology, Biochemistry, Physiology
    • 1st Edition
    • Charles Rouiller + 1 more
    • English
    The Kidney: Morphology, Biochemistry, Physiology, Volume I focuses on present knowledge about the kidney under normal and pathological conditions, as manifested by morphological, biochemical, and physiological studies. The selection first takes a look at the embryonic kidney and the general anatomy and histology of the kidney. Discussions focus on the morphogenesis of transient kidneys, physiology of the fetal nephron, renal malformations, vascularization of the kidney, uriniferous tubules, and innervation of the kidney. The book then examines the histochemistry of the kidney and ultrastructure of the normal and pathological glomerulus. The manuscript ponders on electron microscopy of uriniferous tubules and ultrastructural pathology of tubules and interstitial tissue. Topics include proximal convoluted tubule, basement membranes of the tubules, capillaries, interstitial cells, morphology and functions of the tubular epithelium, fixation and preparation of tissues for electron microscopy, and structure of the submammalian vertebrate tubule. The selection is highly recommended for morphologists, biochemists, physiologists, pathologists, pharmacologists, and clinicians.

  • Mammalian Protein Metabolism

    Volume I
    • 1st Edition
    • H. N. Munro + 1 more
    • English
    Mammalian Protein Metabolism, Volume I focuses on the processes, methodologies, biosynthesis, protein formation, and reactions involved in mammalian protein metabolism. The selection first elaborates on the origin and growth of concepts of protein metabolism, including the development of nitrogen balance as a technique for the study of protein metabolism; identification of proteins as a chemical class; discovery of nitrogen and its biological consequences; and recognition of the importance of nitrogenous compounds. The text then examines protein digestion and absorption in nonruminants and digestion and absorption of nitrogenous compounds in ruminants. Topics include passage of nitrogenous compounds from the rumen; utilization of nitrogenous compounds in the rumen; and endogenous nitrogen entering the reticulum and rumen. The book examines free amino acids and peptides in tissues, metabolic fate of amino acids, protein biosynthesis in mammalian tissues, and metabolism of plasma proteins. Discussions focus on the distribution of proteins between plasma and lymph, interpretation of plasma radioactivities, amino acid activating enzymes, ribosomes and protein synthesis, pathways of amino acid degradation, and synthesis of urea. The selection is a dependable source of data for researchers interested in mammalian protein metabolism.

  • Basic Immunology

    • 1st Edition
    • E. R. Gold + 1 more
    • English
    Basic Immunology focuses on substances that take part in serological reactions, including antigens, antibodies, and the physicochemical nature of immunological reactions. The selection first elaborates on the basic notions of immunity, antigens, immunoglobulins, and the production of antibody. Discussions focus on factors which increase the immune response, production of antibody, biological properties of immunoglobulins, evolution and control of immunoglobulin structure, antigenicity, specific immunity, and resistance. The text then takes a look at the complement system, antigen-antibody reactions, and immediate hypersensitivity. The book ponders on cell-mediated immunity and delayed hypersensitivity, transplantation immunology, and tumor immunology. Topics include production of immunity to neoplasms, immunological aspects of carcinogenesis and growth of established tumors, immunotherapy for experimental neoplasms, donor selection in human-organ transplantation, elicitation of delayed hypersensitivity, and the role of humoral factors in the transfer of delayed hypersensitivity. The selection is a valuable reference for medicine students and researchers interested in basic immunology.

  • Woman's Change of Life

    • 1st Edition
    • Isabel Hutton
    • English
    Woman's Change of Life provides information pertinent to the nature of the menopause and the climacteric is provided. This book presents an outline of a way of life suitable for the important phase in climacteric. Organized into 10 chapters, this book begins with an overview of the prevailing ignorance and fear that surround the whole subject of menopause. This text then provides advice for living and working according to a simple hygienic routine during any trying phase that may arise and thus make it possible to lead a full and efficient life throughout the menopause. Other chapters describe how women can keep fit by means of a wise diet, hydrotherapy, and exercise. This book discusses as well the aspect of marital life in its relation to the climacteric. The final chapter describes the normal climacteric symptoms and explains the necessity of seeking a doctor's help. This book is a valuable resource for physicians and women.

  • Evolving Genes and Proteins

    A Symposium Held at the Institute of Microbiology of Rutgers • the State University with Support from the National Science Foundation
    • 1st Edition
    • Vernon Bryson + 1 more
    • English
    Evolving Genes and Proteins covers the proceedings of the "Evolving Genes and Proteins" symposium, held at the Institute of Microbiology of Rutgers, The State University on September 17 and 18, 1964, with support from the National Science Foundation. The book focuses on the structural and functional features of proteins and nucleic acids. The selection first offers information on lysine biosynthesis and evolution, lipid patterns in the evolution of organisms, and evolution of heme and chlorophyll. Discussions focus on the evolution of the genes of the porphyrin biosynthetic chain, polyunsaturated fatty acids in plants and animals, and diagnostic radiocarbon tracers. The text then examines evolutionary divergence and convergence in proteins; evolution of hemoglobin in primates; and constancy and variability of protein structure in respiratory and viral proteins. The publication takes a look at the comparative aspects of the structure and function of phosphoglucomutase, evolution of dehydrogenases, and enzymatic homology and analogy in phylogeny. The text also ponders on the evolution of an enzyme, role of mutations in evolution, enzyme catalysis and color of light in bioluminescent reactions, and evolution of the lactose utilization gene system in enteric bacteria. The selection is a valuable reference for microbiologists and readers interested in the study of genes and proteins.

  • Analytical Microbiology

    • 1st Edition
    • Frederick Kavanagh
    • English
    Analytical Microbiology focuses on the processes, methodologies, developments, and approaches involved in analytical microbiology, including microbiological, antibiotic, and amino acid assays and dilution methods. The selection first offers information on the theory of antibiotic inhibition zones, microbiological assay using large plate methods, and dilution methods of antibiotic assays. Discussions focus on serial dilution assay, requirements for accurate assay, microbiological assay of riboflavin, laws of adsorption and partition, mechanisms of antibiotic action, and biological considerations affecting the use of statistical methods. The text then ponders on the elements of photometric assaying and automation of microbiological assays. The manuscript elaborates on antibiotic substances, vitamins, and amino acids. Topics include assay organisms, validity, specificity, reliability, and calculation of results of amino acid assays, bacitracin, chloramphenicol, dihydrostreptomycin, erythromycin, neomycin, and streptomycin. The selection is a dependable reference for researchers interested in analytical microbiology.

  • The Peptides

    Methods of Peptide Synthesis
    • 1st Edition
    • Eberhard Schröder + 1 more
    • English
    The Peptides, Volume I: Methods of Peptide Synthesis focuses on detailed description of protecting groups, individual amino acids, and coupling reactions. The publication first offers information on amino-protecting and carboxyl-protecting groups, including carboxyl protection by salt formation, esterification, and amide formation and acyl-type, alkyl-type, and urethane protecting groups. The text then examines the formation of the peptide bond and amino acids. Discussions focus on amino acids with the alcoholic hydroxyl group, sulfur amino acids, basic and acidic amino acids, synthesis of peptides by activation of the amino group, and peptide synthesis by activation of the carboxyl group. The manuscript elaborates on the synthesis of cyclic peptides, depsipeptides, peptoids, and the plastein reaction. Topics include synthesis of plastein-active peptides, glycopeptides, phosphopeptides, and S-peptides. The publication is a dependable source of data for readers interested in the methods of peptide synthesis.

  • The Alkaloids

    Chemistry and Physiology
    • 1st Edition
    • R. H. F. Manske
    • English
    The Alkaloids: Chemistry and Physiology, Volume V: Pharmacology deals with the chemistry and pharmacology of the alkaloids. This book discusses the general pharmacology of morphine, cryptopine-like compounds, toad poisons, and respiratory stimulants. The appraisal of the utility of alkaloids as antimalarials, uterine stimulants, metabolism of cocaine, and optical isomerism-activity relationship are also elaborated. This publication likewise covers the parasympathetic blocking agents as mydriatics, methods of measuring mydriatic activity, alkaloids exhibiting curariform activity, and minor alkaloids of unknown structure. Other topics include the fate of morphine, tropane group, factors affecting cocaine anesthesia, and sympathomimetic mydriatics. This volume is intended for chemists and pharmacologists concerned with alkaloids.

  • Chemistry and Methods of Enzymes

    • 3rd Edition
    • James B. Sumner + 1 more
    • English
    Chemistry and Methods of Enzymes, Third Edition focuses on the processes, methodologies, and reactions in enzyme chemistry, as well as kinetics, nucleases, esterases, and carbohydrates. The publication first underscores the general properties of enzymes, including chemical nature, occurrence, numerical characterization of enzyme concentration, kinetics of enzyme reactions, preparation of commercial enzymes, purification and preservation of enzymes, relations of vitamins to enzymes, and zymogens and kinases. The text then takes a look at esterases and carbohydrates. Topics include pectin depolymerase, heparinase, xylanase, chitinase, dextranase, trehalase, nucleotide phosphatases, glucosulfatase, and gastric lipase. The manuscript examines nucleases, nuclein deaminases, amidases, proteolytic enzymes, and hydrases. Discussions focus on enolase, aconitase, peptidases as metalloproteins, glutaminases, aspartase, urease, adenosine deaminase, and nucleoside phosphorylase. The book also elaborates on iron and copper enzymes, dehydrogenases containing coenzymes I and II, and yellow enzymes. The text is a dependable source of data for chemists and researchers wanting to dig deeper into the chemistry and methods of enzymes.

  • The Biochemistry and Physiology of Bone

    • 1st Edition
    • Geoffrey H. Bourne
    • English
    The Biochemistry and Physiology of Bone focuses on the advancements of techniques, methodologies, and approaches involved in bone studies, including general anatomy, tissues, collagen fibers, and calcification. The selection first offers information on the general anatomy and histology of bone and bone as a mechanical engineering problem. Topics include strength of healing fractures, nervous influences on bone, growth of the skull, bone strength, primary constituents of bony tissue, and types and organization of bony tissue. The text then elaborates on the ground substance of connective tissue and cartilage, organic matrix of bone, and collagen fibers of connective tissue. The publication takes a look at the ultrastructure and distribution of mineral salts in bone tissue, osteoblast, and osteoclast. Discussions focus on microscopical appearances, integration of morphological and histochemical studies, cytochemistry, distribution of inorganic salts in bone tissue, relation of collagen to its environment, and structure of collagen fibers. The publication also examines pathological calcification, effects of radiation on bone, parathyroid glands and bone, and anterior pituitary regulation of skeletal development. The selection is a dependable source of data for researchers interested in the biochemistry and physiology of bone.

  • Determination of the Size and Shape of Protein Molecules

    A Laboratory Manual of Analytical Methods of Protein Chemistry (Including Polypeptides), Vol. 3
    • 1st Edition
    • P. Alexander + 1 more
    • English
    Analytical Methods of Protein Chemistry, Volume 3: Determination of the Size and Shape of Protein Molecules provides information pertinent to the analysis and isolation of protein. This book deals with the measurement of the macromolecular properties of proteins. Organized into seven chapters, this volume begins with an overview of the theory and practice of the electron microscope to allow an understanding of the type of object that may be examined. This text then describes the methods of making protein molecules conform to such an ideal, which are the techniques of specimen preparation. Other chapters consider the determinations of osmotic pressures of proteins. This book discusses as well the experimental basis for the theory of the diffusion process in liquids. The final chapter deals with the technical problem characteristics of light-scattering. This book is a valuable resource for electron microscopists, protein chemists, biologists, physicist, physico-chemists, scientists, and research workers.

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