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Elsevier

Books in Life sciences

  • Stability and Stabilization of Biocatalysts

    • 1st Edition
    • Volume 15
    • F.J. Plou + 2 more
    • A. Ballesteros
    • English
    Six years after the symposium on Stability and Stabilization of Enzymes, a second symposium, Stability and Stabilization of Biocatalysts, on which this book is based, was organized. At the symposium, 210 participants representing all continents came together to learn from 150 oral and poster communications.The volume brings up-to-date the work already going on, and identifies possible breakthroughs in the research. This timely book therefore presents cutting edge developments in topics such as non-covalent processes in solution, protein engineering and thermophile enzymes, immobilized enzymes, non-conventional media, and whole cells.An excellent addition to the available literature, it will make a useful contribution to this key area of applied biocatalysis.

  • Cumulative Subject Index

    • 1st Edition
    • Volume 56
    • Gerald Litwack + 1 more
    • English
    First published in 1943, Vitamins and Hormones is the longest-running serial published by Academic Press. In the early days of the Serial, the subjects of vitamins and hormones were quite distinct. Now, new discoveries have proved that several of the vitamins function as hormones and many of the substances inferred by the title of the Serial function in signal transduction processes. Accordingly, the Editor-in-Chief has expanded the scope of the serial to reflect this newer understanding of function-structure relationships in cellular communication. The Editorial Board now reflects expertise in the field of hormone action, vitamin action, X-ray crystal structure, physiology, and enzyme mechanisms. Under the capable and qualified editorial leadership of Dr. Gerald Litwack, Vitamins and Hormones continues to publish cutting-edge reviews of interest to endocrinologists, biochemists, nutritionists, pharmacologists, cell biologists, and molecular biologists.The 56th volume of Vitamins and Hormones is a cumulative index of volumes 30 through 55.

  • Nitric Oxide in Brain Development, Plasticity, and Disease

    • 1st Edition
    • Volume 118
    • R.R. Mize + 3 more
    • English
    Nitric oxide, "Molecule of the Year" in 1995, continues to be one of the most widely studied molecules in brain research. This excellent volume elucidates the implications of this gas in a variety of brain processes.The volume is divided into five sections, describing: the mechanisms underlying the release and action of Nitric Oxide in the CNS, and the distribution of Nitric Oxide in the brain using various techniques; how Nitric Oxide interacts with and regulates the N-methyl-D-aspartate receptor; the role of Nitric Oxide in pathway refinement and synapse stabilization in the developing CNS; the role of Nitric Oxide in adult brain plasticity including long-term potentiation and depression; and the role of Nitric Oxide in brain injury such as occurs during ischemia and other events produced by glutamate neurotoxicity, and in neuroprotective mechanisms that promote neuron survival.Nitric Oxide in Brain Development, Plasticity, and Disease is the first Progress in Brain Research volume to be published in abstracted form on the World Wide Web. It includes title pages, abstracts, selected figures, and complete references. It also includes a digital brain atlas for readers to view a mouse brain in a three-dimensional full-color rendition, and much more.

  • Neuronal Degeneration and Regeneration: From Basic Mechanisms to Prospects for Therapy

    • 1st Edition
    • Volume 117
    • F.W. Van Leeuwen + 4 more
    • English
    This book is the result of the 20th International Summer School in Brain Research, organized in August 1997 in Amsterdam, by the Netherlands Institute for Brain Research at the Royal Netherlands Academy of Sciences. It is the first book that provides a complete overview of the field of neurodegeneration and regeneration including spinal cord injury, neurodegenerative diseases and therapy. Divided into five sections, the first two sections give an overview of fundamental research on nerve cell death, neuronal survival, neurite outgrowth and guidance. Extensive attention is given to the role of neurotrophins, their receptor tyrosine kinases and cell-adhesion molecules in development and regeneration of the nervous system. The third section of the book is devoted to research involving human neurodegenerative diseases and emerging treatment strategies. Section four focusses on recent advances in the understanding of pathophysiological mechanisms underlying neurodegenerative diseases, including Alzheimer's, Parkinson's and Huntington's diseases along with prion diseases. Novel insights into the neuropathological hallmarks of these diseases, as well as into transgenic animal models, the involvement of environmental factors, and genomic and mRNA changes that can cause neurodegeneration. The final section of this volume reveals recent developments in the use of cell and gene therapy to treat neurodegenerative disease and lesion-related deficits. Implantation of genetically modified cells, direct gene transfer with viral vectors and the first clinical trials with encapsulated genetically modified cells in patients suffering from amyotrophic lateral scelerosis are examples of new therapeutic strategies treating neurodegenerative diseases.The book is of particular interest to departments of neuroscience, neurological clinics and departments, the pharmalogical industry and medical libraries.

  • Ion Channels, Part C

    • 1st Edition
    • Volume 294
    • John N. Abelson + 1 more
    • English
    General Description of the Volume:This volume and its companion Volume 293 present techniques for the study of ion channels, ranging from the molecular to the physiological level. These volumes supplement Volume 207 of Methods in Enzymology. General Description of the Series:The critically acclaimed laboratory standard for more than forty years, Methods in Enzymology is one of the most highly respected publications in the field of biochemistry. Since 1955, each volume has been eagerly awaited, frequently consulted, and praised by researchers and reviewers alike. Now with more than 300 volumes (all of them still in print), the series contains much material still relevant today--truly an essential publication for researchers in all fields of life sciences.

  • Current Topics in Developmental Biology

    • 1st Edition
    • Volume 41
    • English
    This Series provides a comprehensive survey of the major topics in the field of developmental biology. The volumes are valuable to researchers in animal and plant development, as well as to students and professionals who want an introduction to cellular and molecular mechanisms of development. The Series has recently passed its 30-year mark, making it the longest-running forum for contemporary issues in developmental biology.

  • Heart Development

    • 1st Edition
    • Richard P. Harvey + 1 more
    • English
    This book examines recent studies revealing that the same genes are responsible for development of parallel features between species, and that the heart develops similarly across all species. It includes research being conducted concerning cardiac development, tissue interaction, and organ formation. The text attempts to provide a greater understanding of the underlying causes of heart failure, heart muscle diseases, congenital malformations, and other heart diseases and defects.

  • Cell Lineage and Fate Determination

    • 1st Edition
    • Sally A. Moody
    • English
    Cell Lineage and Fate Determination provides a comprehensive view of the mechanisms regulating cell lineage and fate determination in an effort to understand how the fertilized egg is transformed into a complex of specialized tissues. It presents basic information on eight different animal models and recent developmental biological research done in each model. The book provides a focused forum presenting key information for researchers studying various aspects of developmental and cellular biology. Extensive use of tables and black-and-white and color figures helps illustrate each model. The book concludes by discussing future goals for bringing cellular, molecular, and genetic research to clinical applications and tissue replacement therapies.

  • Current Topics in Developmental Biology

    • 1st Edition
    • Volume 44
    • English
    Current Topics in Developmental Biology provides a comprehensive survey of the major topics in the field of developmental biology. The volumes are valuable to researchers in animal and plant development, as well as to students and professionals who want an introduction to cellular and molecular mechanisms of development. The series has recently passed its 30-year mark, making it the longest-running forum for contemporary issues in developmental biology.

  • Investigating Biological Systems Using Modeling

    Strategies and Software
    • 1st Edition
    • Meryl E. Wastney + 4 more
    • English
    Investigating Biological Systems Using Modeling describes how to apply software to analyze and interpret data from biological systems. It is written for students and investigators in lay person's terms, and will be a useful reference book and textbook on mathematical modeling in the design and interpretation of kinetic studies of biological systems. It describes the mathematical techniques of modeling and kinetic theory, and focuses on practical examples of analyzing data. The book also uses examples from the fields of physiology, biochemistry, nutrition, agriculture, pharmacology, and medicine.

  • Current Topics in Developmental Biology

    • 1st Edition
    • Volume 43
    • English
    This Series provides a comprehensive survey of the major topics in the field of developmental biology. The volumes are valuable to researchers in animal and plant development, as well as to students and professionals who want an introduction to cellular and molecular mechanisms of development. The Series has recently passed its 30-year mark, making it the longest-running forum for contemporary issues in developmental biology.

  • The Epilepsies

    Etiologies and Prevention
    • 1st Edition
    • Prakash Kotagal + 1 more
    • English
    Tremendous advances in our understanding of epilepsy have occurred in the last two decades. Techniques such as electroencephalograp... neuroimaging, neurosurgery and neuropsychology are giving us a better understanding of the pathogenesis of epilepsy. Additionally major breakthroughs are taking place in the laboratories of scientists studying genetics, embryogenesis, neuropathology, neurochemistry and pharmacology. These advances provide a much better understanding of why patients develop epilepsy, reshaping the way in which the epileptic patient is cared for. This book presents the most current information on the various etiologies of epilepsy, their treatments, and their possible prevention. Kotagal and Lüders have assembled 80 internationally known experts to compile this authoritative, comprehensive, and well-rounded work.The Epilepsies is a one-of-a-kind reference that will be of interest to specialists and basic scientists involved in the study of epilepsy, adult and pediatric neurologists, neurosurgeons, residents and fellows in these areas, and pediatricians who frequently encounter children with neurological problems. This major work brings together the most up-to-date research on the causes of epilepsy and other associated diseases which cause seizures. It presents data on infections, trauma, mesial temporal sclerosis, cerebral dysgenesis, brain tumors, vascular lesions, stroke, as well as genetic, metabolic and toxic causes of epilepsy. The book also looks at drug treatment and new surgical techniques that have proven useful in alleviating epileptic and other related seizures.

  • Veterinary Vaccines and Diagnostics

    • 1st Edition
    • Volume 41
    • English
    This volume of Advances in Veterinary Medicine, derived in part from the First Veterinary Vaccines and Diagnostic Conferences, deals with vaccines, an especially active area of veterinary research and controversy.

  • Intertidal Fishes

    Life in Two Worlds
    • 1st Edition
    • Michael H. Horn + 2 more
    • English
    Intertidal Fishes describes the fishes inhabiting the narrow strip of habitat between the high and low tide marks along the rocky coastlines of the world. It analyzes the specialized traits of these fishes that have adapted to living in the dynamic and challenging space where they are alternately exposed to the air and submerged in water with the ebb and flow of the tides. This book provides a comprehensive account of fishes largely overlooked in many previous studies of intertidal organisms and emphasizes how they differ from fishes living in other deeper-water habitats. Coverage includes air breathing, movements and homing, sensory systems, spawning and parental care, feeding habits, community structure, systematic relationships, distribution patterns, and the fossil record in the intertidal zone.

  • The Gene Knockout Factsbook, Two-Volume Set

    • 1st Edition
    • Tak W. Mak
    • English
    The FactsBooks Series has established itself as the best source of easily-accessible and accurate facts about protein groups. Described as "a growing series of excellent manuals" by Molecular Medicine Today, and "essential works of reference" by Trends in Biochemical Sciences, the FactsBooks have become the most popular comprehensive data resources available. Using an easy-to-follow format and drawing from meticulous research, the Factsbooks will keep you up-to-date with the latest advances in structure, amino acid sequences, physicochemical properties, and biological activity. The Gene Knockout FactsBook contains entries, grouped into subject disciplines, covering immunology, neurobiology, development, cancer, and other knockouts. It describes more than 600 gene knockouts described and listed in alphabetical order for easy reference.

  • Encyclopedia of Human Nutrition

    • 1st Edition
    • Lindsay Allen + 2 more
    • English
    This encyclopedia provides comprehensive coverage of all aspects of human nutrition, including clinical applications. Most of the chapters represent brand new expositions of the field, yet the Encyclopedia also includes relevant sections from the Encyclopaedia of Food Science, Food Technology, and Nutrition, which have been revised, updated, and rewritten, plus that reference work's award-winning index system. Virtually everyone will find the Encyclopedia of Human Nutrition easy to use--from the experienced researcher requiring a specific piece of information to the general reader who needs an overview of a new and unfamiliar topic. The work is highly structured and cross-referenced, and leads the reader to the required information as quickly and as intuitively as possible. Of the more than 270 articles, each offers "links" to related articles and also lists "Further Reading Topics," directing the reader to important texts in that area. The Encyclopedia takes a truly international approach where relevant. It details various national conventions and standards and explains nutritional policy differences between the developed and developing world. Nutritionists, clinical nutritionists, dietitians, and allied health workers are sure to benefit and make great use of this resource.

  • Encyclopedia of Reproduction

    • 1st Edition
    • Michael K. Skinner + 2 more
    • English
    The more than 550 articles in the Encyclopedia of Reproduction encompass every aspect of the biology of reproduction throughout the entire animal kingdom, covering invertebrates to humans. Each article includesa glossary and an introduction, as well as illustrations and a bibliography. Extensive aids to the reader are provided through a detailed subject index, cross references to related articles, and an index of articles by category. The Encyclopedia isdesigned to answer any and all questions related to this fundamentally important field, in non-mammalian as well as mammalian systems, from the most basic to the latest advances in assisted reproduction in humans.

  • Fundamentals of Weed Science

    • 2nd Edition
    • Robert L Zimdahl
    • English
    The topics covered in this Second Edition include the characteristics of weeds, weed reproduction and dispersal, weed ecology, allelopathy, plant competition, various means of controlling weeds, and weed management systems. This book discusses new developments in weed science and relevant aspects of the science's historical development. It focuses on weed biology and ecology along with the use of herbicides and chemical weed control.

  • Enzymology of Disturbed Soils

    • 1st Edition
    • Volume 26
    • S. Kiss + 2 more
    • English
    The disturbance of soils, like other phenomena of environmental pollution, encountered in so many areas all over the world, has become a subject of extensive concern and has led to a vast amount of literature in the field of enzymology, too.The book is the first comprehensive and updated review of the enzymological literature on three great categories of disturbed soils, including their remediation. The volume consists of three sections: I. Enzymology of oil-contaminated soils; II. Enzymology of soils affected by industrial emissions; and III, enzymology of technogenic soils. Within each section the reviewed studies are grouped by country.The volume will be of great value to soil scientists, environmental scientists, conservationists, and many other scientists in these and related fields.

  • Handbook of Behaviorism

    • 1st Edition
    • William O'Donohue + 1 more
    • English
    Handbook of Behaviorism provides a comprehensive single source that summarizes what behaviorism is, how the various "flavors" of behaviorism have differed between major theorists both in psychology and philosophy, and what aspects of those theories have been borne out in research findings and continue to be of use in understanding human behavior.

  • Cumulative Subject Index, Volumes 20-39

    • 1st Edition
    • Volume 40
    • English
    Volume 40 of Advances in Genetics brings together a complete listing of subjects covered in Volumes 20-39 of this premier series. In one easy-to-use source, the interested librarian, student, and researcher can find references to specific articles on topics such as tumor suppressor genes, chromosome rearrangements, apoptosis, bax genes, the human genome project, muscular dystrophy, gene therapy, transcription factors, and transgenic mouse models. This cumulative subject index will serve not only as a complete overview of the major topics published in Advances in Genetics, but also as an indicator of the progress made in genetic research over the years.

  • Vitamins and Hormones

    • 1st Edition
    • Volume 55
    • Gerald Litwack + 1 more
    • English
    Under the capable and qualified editorial leadership of Dr. Gerald Litwack, Vitamins and Hormones continues to publish cutting-edge reviews of interest to endocrinologists, biochemists, nutritionists, pharmacologists, cell biologists, and molecular biologists. First published in 1943, Vitamins and Hormones is the longest-running serial published by Academic Press. In the early days of the Serial, the subjects of vitamins and hormones were quite distinct. Now, new discoveries have proved that several of the vitamins function as hormones and many of the substances inferred by the title of the Serial function in signal transduction processes. Accordingly, the Editor-in-Chief has expanded the scope of the Serial to reflect this newer understanding of function- structure relationships in cellular communication. The Editorial Board now reflects expertise in the field of hormone action, vitamin action, X-ray crystal structure, physiology, and enzyme mechanisms. Volume 55 of Vitamins and Hormones covers steroid hormone action, and includes two additional contributions on calcium and on peptide hormones.

  • Advances in Botanical Research

    • 1st Edition
    • Volume 29
    • English
    Advances in Botanical Research is a multi-volume publication that brings together reviews by recognized experts on subjects of importance to those involved in botanical research. For more than thirty years, Advances in Botanical Research has earned a reputation for excellence in the field. For those working on plant pathology, Advances in Plant Pathology has also carved a niche in the plant sciences during its decade of publication. Academic Press has merged Advances in Plant Pathology into Advances in Botanical Research. The plant science community will find that the merger of these two serials will provide one comprehensive resource for the field. To ensure complete coverage, John Andrews and Inez Tommerup, the editors of Advances in Plant Pathology, have joined the editorial board of the new series, which will include equal coverage of plant pathology and botany in both thematic and mixed volumes. The first few volumes of the new series will be slanted toward botany or plant pathology; however, future eclectic volumes will be fully integrated.The resulting synergy of these two serials greatly benefits the plant science community by providing a more comprehensive resource under one roof. The joint aim is to continue to include the very best articles, thereby maintaining the status of a high impact factor review series.

  • Cumulative Subject Index

    • 1st Edition
    • Volume 45
    • English
    Advances in Pharmacology provides a rich collection of reviews on timely topics. Emphasis is placed on the molecular bases of drug action, both applied and experimental. For easy reference, this volume provides a cumulative subject index covering Volumes 25-44.

  • Nitric Oxide, Part C: Biological and Antioxidant Activities

    • 1st Edition
    • Volume 301
    • John N. Abelson + 1 more
    • English
    General Description of the Volume:Nitric Oxide, recently designated "Molecule of the Year," impinges on a wide range of fields in biological research, particularly in the areas of biomedicine and cell and organismal biology, as well as in fundamental chemistry. This volume will be a valuable resource for the experienced researcher as well as for those newly entering the field. This volume continues the coverage of new and important tools for the elucidation of Nitric Oxide action initiated in Volumes 268 and 269 of Methods in Enzymology. Techniques for researching the physiology and toxicity of nitric oxide in cellular and organismal systems are highlighted.General Description of the Series:The critically acclaimed laboratory standard for more than forty years, Methods in Enzymology is one of the most highly respected publications in the field of biochemistry. Since 1955, each volume has been eagerly awaited, frequently consulted, and praised by researchers and reviewers alike. Now with more than 300 volumes (all of them still in print), the series contains much material still relevant today--truly an essential publication for researchers in all fields of life sciences.

  • Ion Channel Factsbook

    Voltage-Gated Channels
    • 1st Edition
    • Volume 4
    • William J. Brammar
    • English
    The Academic Press FactsBooks series has established itself as the best source of easily-accessible and accurate facts about protein groups. Described as 'a growing series of excellent manuals' by Molecular Medicine Today, and 'essential works of reference' by Trends in Biochemical Sciences, the FactsBooks have become the most popular comprehensive data resources available. As they are meticulously researched and use an easy-to-follow format, the FactsBooks will keep you up-to-date with the latest advances in structure, amino acid sequences, physicochemical properties, and biological activity.In a set of four interrelated volumes, The Ion Channel FactsBook provides a comprehensive framework of facts about channel molecules central to electrical signaling phenomena in living cells. The fourth volume is devoted to Voltage-gated Channel Families, including those molecular complexes activated or modulated by calcium, potassium, and chloride.

  • Green Fluorescent Proteins

    • 1st Edition
    • Volume 58
    • English
    This volume is an authoritative and comprehensive treatment of the approaches and techniques used for Green Fluorescent Proteins (GFP). The primary focus of this work is on research using biological systems. The volume covers all aspects of GFP, from its expression in different organisms to specific microscopic and data analysis methods.

  • Oxidants and Antioxidants, Part B

    • 1st Edition
    • Volume 300
    • John N. Abelson + 1 more
    • English
    General Description of the Series:The critically acclaimed laboratory standard for more than forty years, Methods in Enzymology is one of the most highly respected publications in the field of biochemistry. Since 1955, each volume has been eagerly awaited, frequently consulted, and praised by researchers and reviewers alike. Now with more than 300 volumes (all of them still in print), the series contains much material still relevant today--truly an essential publication for researchers in all fields of life sciences.

  • Eukaryotic Transcription Factors

    • 3rd Edition
    • David S. Latchman
    • English
    Familiarity with the mechanisms of eukaryotic gene regulation is now essential for scientists and students in both clinical and basic disciplines. However, the vast array of transcription factors, which are central to such regulation, can prove daunting to students and newcomers to this fascinating field of molecular genetics. The Third Edition of Eukaryotic Transcription Factors provides the reader with a clear and concise understanding not only of transcription factors, but also of their vital role in the regulation of transcription in different cell types during development and in disease.Revised and completely up-to-date, the Third Edition of Eukaryotic Transcription Factors has been extensively rewritten to reflect the rapid advances in the field. These include the emerging roles of specific co-activator molecules such as CBP in the action of a number of different transcription factors emphasizing particularly their ability to modulate chromatin structure. New sections cover current methods for determining DNA binding specificity, regulation by protein degradation and processing, Pax family transcription factors, and novel anti-oncogenic transcription factors, as well as a discussion of transcription factors in human diseases. A special new color section illustrates the various aspects of transcription factor structure.

  • Advances in Clinical Chemistry

    • 1st Edition
    • Volume 33
    • English
    For more than thirty years, this serial has broadened the technical scope and expanded the scientific base of clinical chemistry. These volumes clarify the areas of molecular biology, informatics, and the monitoring of physiological parameters in critical situations as they pertain to clinical chemistry. Each volume of Advances in Clinical Chemistry contains an index, and each chapter includes references.

  • Identification of Pathological Conditions in Human Skeletal Remains

    • 2nd Edition
    • Donald J. Ortner
    • English
    Identification of Pathological Conditions in Human Skeletal Remains provides an integrated and comprehensive treatment of pathological conditions that affect the human skeleton. There is much that ancient skeletal remains can reveal to the modern orthopaedist, pathologist, forensic anthropologist, and radiologist about the skeletal manifestations of diseases that are rarely encountered in modern medical practice. Beautifully illustrated with over 1,100 photographs and drawings, this book provides essential text and materials on bone pathology, which will improve the diagnostic ability of those interested in human dry bone pathology. It also provides time depth to our understanding of the effect of disease on past human populations.

  • Cumulative Subject Index

    • 1st Edition
    • Volume 42
    • English
    This Series provides a comprehensive survey of the major topics in the field of developmental biology. The volumes are valuable to researchers in animal and plant development, as well as to students and professionals who want an introduction to cellular and molecular mechanisms of development. The Series has recently passed its 30-year mark, making it the longest-running forum for contemporary issues in developmental biology.

  • Green Fluorescent Proteins

    • 1st Edition
    • Volume 58
    • English
    This volume is an authoritative and comprehensive treatment of the approaches and techniques used for Green Fluorescent Proteins (GFP). The primary focus of this work is on research using biological systems. The volume covers all aspects of GFP, from its expression in different organisms to specific microscopic and data analysis methods.

  • Advances in Microbial Physiology

    • 1st Edition
    • Volume 40
    • English

  • Cytokines

    • 1st Edition
    • Volume 52
    • English
    Our most complete understanding of hormone receptor signaling may be exemplified in a family of hormones and receptors known as the cytokine superfamily. This volume is devoted to describing members of this hormone/receptor family from their molecular structures to their physiological effects. These hormones are not only biologically fascinating, but are also tremendously useful medicines.The first three chapters review the basic events in binding and signaling. The remaining papers present the cellular biology and physiological processes controlled by these hormones and receptors.

  • Metabolic Engineering

    Principles and Methodologies
    • 1st Edition
    • George Stephanopoulos + 2 more
    • English
    Metabolic engineering is a new field with applications in the production of chemicals, fuels, materials, pharmaceuticals, and medicine at the genetic level. The field's novelty is in the synthesis of molecular biology techniques and the tools of mathematical analysis, which allow rational selection of targets for genetic modification through measurements and control of metabolic fluxes. The objective is to identify specific genetics or environmental manipulations that result in improvements in yield and productivities of biotechnological processes. Key features of the book are pathway integration and the focus on metabolic flux as a fundamental determinant of cell physiology. The book keeps mathematical complexity to a minimum, and provides a glossary of biological terms to facilitate use of the book by a broader spectrum of readers. A web page exists to communicate updates of the codes and homework problems.

  • Oxidants and Antioxidants, Part A

    • 1st Edition
    • Volume 299
    • John N. Abelson + 1 more
    • English
    The critically acclaimed laboratory standard for more than forty years, Methods in Enzymology is one of the most highly respected publications in the field of biochemistry. Since 1955, each volume has been eagerly awaited, frequently consulted, and praised by researchers and reviewers alike. Now with more than 300 volumes (all of them still in print), the series contains much material still relevant today--truly an essential publication for researchers in all fields of life sciences.

  • The Human Genome

    A User's Guide
    • 1st Edition
    • R. Scott Hawley + 1 more
    • English
    The Human Genome: A User's Guide provides a concise discussion of contemporary and relevant topics in human genetics. It begins coverage of the fundamental concepts of genetics and heredity, then illustrates these concepts as they relate to the development of human sexual differentiation and sexuality. The book describes the role of the X and Y chromosomes, the role of hormone-controlled differential gene expression in sex determination, and the role of genetics in sexual orientation and sex-role development. The Human Genome discusses the interface between science and society, covering the basic intellectual processes that underlie genetic analysis and gene therapy. It also looks at the use of cloning techniques to search for genes responsible for such human disease states as cystic fibrosis, cancer, AIDS, and mental illness. Written in an inviting and engaging style, The Human Genome meets the interests and answers the questions of today's students.

  • International Review of Cytology

    A Survey of Cell Biology
    • 1st Edition
    • Volume 186
    • English
    International Review of Cytology presents current advances and comprehensive reviews in cell biology-both plant and animal. Articles address structure and control of gene expression, nucleocytoplasmic interactions, control of cell development and differentiation, and cell transformation and growth. Authored by some of the foremost scientists in the field, each volume provides up-to-date information and directions for future research.

  • Dynamic Aquaria

    Building Living Ecosystems
    • 2nd Edition
    • Walter H. Adey + 1 more
    • English
    This unique, respected book brings together the diverse modeling efforts of two decades of research in the Smithsonian Marine Systems Laboratory. Dynamic Aquaria, Second Edition integrates the fields of ecology and aquarium science to give readers a better understanding of simulated ecosystem function and ecological food webs. In a new larger format, the Second Edition presents the limitations imposed upon these webs by their compression into micro- and mesocosms. The book demonstrates mainstream ecological research alongside practical issues of aquaria construction, and successfully presents essential aspects of ecological systems in an accessible fashion. It describes the introduction and testing of numerous new techniques for simulating the functional and biodiversity of ecosystems in relatively small dimension. The Second Edition includes new advancements in the field and two new chapters on suspended particulates (inorganic and organic) and biomineralization. Approximately one-third of the photographs are entirely new.

  • Advances in Virus Research

    • 1st Edition
    • Volume 51
    • English

  • Analysis of Triplet Repeat Disorders

    • 1st Edition
    • English
    The clinical picture of diseases, caused by trinucleotide repeats, such as fragile X syndrome, myotonic dystrophy, Huntington's disease and forms of spinocerebella ataxia, provide the starting point for this authoritative review volume.The book proceeds to integrate the current understanding of the molecular pathologies of these diseases, their genotype-phenotype relationships, the mutational processes involved and the laboratory and clinical issues relating to genetic testing for these disorders.Clinicians and researchers in genetics, neuroscience, pediatrics and psychiatry will all benefit from the comprehensive overviews contributed by recognized world experts.

  • The Psychology of Music

    • 2nd Edition
    • Diana Deutsch
    • English
    The aim of the psychology of music is to understand musical phenomena in terms of mental functions--to characterize the ways in which one perceives, remembers, creates, and performs music. Since the First Edition of The Psychology of Music was published the field has emerged from an interdisciplinary curiosity into a fully ramified subdiscipline of psychology due to several factors. The opportunity to generate, analyze, and transform sounds by computer is no longer limited to a few researchers with access to large multi-user facilities, but rather is available to individual investigators on a widespread basis. Second, dramatic advances in the field of neuroscience have profoundly influenced thinking about the way that music is processed in the brain. Third, collaborations between psychologists and musicians, which were evolving at the time the First Edition was written, are now quite common; to a large extent now speaking a common language and agreeing on basic philosophical issues.The Psychology of Music, Second Edition has been completely revised to bring the reader the most up-to-date information, additional subject matter, and new contributors to incorporate all of these important variables.

  • Heart Metabolism in Failure

    • 1st Edition
    • Volume 4
    • R.A. Altschuld + 1 more
    • English
    Heart failure continues to be a major public health problem in the United States with close to half a million new cases diagnosed each year. Moreover, deaths from heart failure are on the increase, in part because of advances in the treatment of other fatal diseases, and in part from the prevalence of lifestyles indifferent to the risk factors for heart disease. This is not to say that no progress has been made in the treatment of heart failure. While for many years treatment was confined to the management of the symptoms, in recent years with the advent of ACE inhibitor and ß blacker therapies, real improvements in cardiac function and life expectancy have been achieved (Volume 4B, Leier). On a more basic level, enormous advances have been made in describing many of the changes in structure and function of the heart and the parallel neurohumoral and circulatory adaptations that occur during the onset of failure. These advances have been made not only by using various animal models of heart failure, but also using fresh failing human heart tissue, which has become readily available for experimental investigation since the advent of cardiac transplantation.Unde... the significance of many of these changes that occur during the transition to failure and the role they play in the etiology of failure is, however, a much more difficult task. These are exciting times in heart failure research. It is as though many of the pieces of the jigsaw puzzle are available but the puzzle has yet to be assembled. The objective of these volumes is to bring together some advances that have been made in recent years in defining one aspect of the failing heart, that is, the role of altered metabolism, in order to facilitate assembly of the puzzle.

  • The Primate Nervous System, Part II

    • 1st Edition
    • Volume 14
    • T. Hokfelt + 2 more
    • English
    This volume is the second in the planned coverage of the neurochemical circuitry of the primate central nervous system. While this volume contains only two chapters, their topics and the extraordinarily comprehensive coverage with which the authors have dealt with their topics, will nevertheless contribute equal amounts of knowledge, wisdom, and opportunities for future research extensions as have every volume in this unique series. As such, these chapters extend the goals of this primate series to develop a broad coverage of human and non-human primate chemical neuroanatomic details in a volume which makes clear the known and desirable appreciation for differences between and among subsets of primate brains.The first chapter covers the primate thalamus with equal emphases on new world, old world, pro-simian and human anatomic details and their differences. The second undertakes a comparably comprehensive examination of one of the most intensively studied regions of the primate brain, namely the primate visual cortex. While much has been studied, both chapters also reveal how much remains for future efforts in these enormously important regions which are the archetypes of primate sub-cortical and cortical function.

  • Perception and Cognition at Century's End

    History, Philosophy, Theory
    • 1st Edition
    • Julian Hochberg
    • English
    Perception and Cognition at Century's End contains cognitive psychology surveys that are up-to-date and historically based, as well as references to the development of cognitive psychology over the past century. The book can serve as a central or specialized text for a range of psychology courses.

  • Neurotransmitter Transporters

    • 1st Edition
    • Volume 296
    • John N. Abelson + 1 more
    • English
    General Description of the Series:Neurotransmit... Transporters focuses on biochemical, electrophysiological... pharmacological, molecular, and cell biological approaches used to study neurotransmitter transport systems. The articles provide detailed descriptions of procedures that should enable the reader to understand how they are accomplished and to repeat or adapt them for their own experimental needs. This book is the first to focus on methods that have been the basis for the rapid development of this area.General Description of the Series:The critically acclaimed laboratory standard for more than forty years, Methods in Enzymology is one of the most highly respected publications in the field of biochemistry. Since 1955, each volume has been eagerly awaited, frequently consulted, and praised by researchers and reviewers alike. Now with more than 300 volumes (all of them still in print), the series contains much material still relevant today--truly an essential publication for researchers in all fields of life sciences.

  • Chemistry and Biology

    • 1st Edition
    • Volume 52
    • English
    Alkaloids are a major group of natural products derived from a variety of organisms, which are widely used as medicinal and biological agents. This Series is world-renowned as the leading compilation of current reviews of this vast field. Internationally acclaimed for more than 40 years, this Series, founded by the late Professor R.H.F. Manske, continues to provide outstanding coverage of the rapidly expanding field of the chemotaxonomy, structure elucidation, synthesis, biosynthesis, and biology of all classes of alkaloids from higher and lower plants, marine organisms, or various terrestrial animals. Each volume provides, through its distinguished authors, up-to-date and detailed coverage of particular classes or sources of alkaloids. Over the years, this Series has become the standard in natural product chemistry to which all other book series aspire. The Alkaloids: Chemistry and Biology endures as an essential reference for all natural product chemists and biologists who have an interest in alkaloids, their diversity, and their unique biological profile.

  • Proteins

    Analysis and Design
    • 1st Edition
    • Ruth Hogue Angeletti
    • English
    Proteins: Analysis and Design focuses solely on individual experimental approaches, rather than on specific classes of proteins. The book provides insight into the important issues in protein science and how one can cope with them. These include all issues which explore the detailed relationship of protein structure to function.

  • Handbook of Marine Mammals

    The Second Book of Dolphins and the Porpoises
    • 1st Edition
    • Volume 6
    • English
    Some of the world's most beautiful, intelligent and highly adapted mammals inhabit our seas and oceans, and have stirred the human imagination for many centuries. As our knowledge of marine mammals grows, the need exists for a reliable and complete reference to the ecology and biology of these fascinating creatures. The Handbook of Marine Mammals series was founded with this in mind and now reaches its conclusion with this sixth and final volume. Within the pages of this classic series, scientists, conservationists and informed layperson alike can find the definitive review of all the world's whales, dolphins, porpoises, seals, sea lions, and related species as well as sea otters and sea cows.Volume 6 covers the remaining dolphins and porpoises in a series of 17 chapters, each written by a specialist author with extensive personal research experience of the species. Each chapter provides a description of the species, and includes sections on the aspects of distribution and abundance, anatomy, physiology, behavior, reproduction, parasites and diseases and the impact of human activity on the animal's population and well-being. Numerous maps, photos and drawings illustrate the text.

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