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Elsevier

Books in Life sciences

  • Principles of Immunotherapy in Breast and Gastrointestinal Cancers

    Activity, Mechanisms of Resistance and New Sensitization Strategies
    • 1st Edition
    • Michele Ghidini
    • English
    Principles of Immunotherapy in Breast and Gastrointestinal Cancers: Activity, Mechanisms of Resistance, and New Sensitization Strategies presents updated research findings on immunotherapy, with a special focus on the mechanisms of resistance of those cancer types and how to overcome them.The book discusses topics such as tumor cell-intrinsic and -extrinsic mechanisms of cancer resistance to immunotherapy; the role of currently available biomarkers; strategies to overcome therapeutic resistance; sensitizing agents for cancer resistance to cell-mediated immunotherapy; and immunotherapeutic approaches, mechanisms of resistance, and sensitizing strategies in gastroesophageal and biliopancreatic tumors and colorectal cancer.It is a valuable resource for researchers, students, and members of the biomedical and medical fields who want to learn more about resistance to immunotherapy and how to overcome it.

  • Neurologic Channelopathies

    • 1st Edition
    • Volume 203
    • English
    Neurological Channelopathies, Volume 203 begins with an introductory overview highlighting common mechanistic themes that cut across different CNS and PNS presentations, but that also have potential for common treatment approaches, considering classification, genetics, and fundamental physiology of ion channels. Subsequent chapters present a detailed consideration of all genetic and immunological channelopathies. Each chapter considers Pathophysiological underpinnings - genetic or immunological; Clinical presentations; Diagnostic approach; and Treatment and management.In the last 15 years, a combination of detailed clinical, genetic, molecular electrophysiological... and immunological research has combined to result in a deep understanding of a subgroup of neurological diseases spanning the central and peripheral nervous system and which have become known collectively as the Neurological Channelopathies. Although it was originally considered that significant ion channel dysfunction would not be compatible with life, we now know this is often not the case, although severe disease can often be the result. Given these major advances, it is now the right time to combine this knowledge into a single HCN volume dedicated to the topics at hand.

  • Siderophore and Related Natural Products Biosynthesis

    • 1st Edition
    • Volume 702
    • English
    Methods in Enzymology Volume 702 highlights new advances in the field, with this new volume presenting interesting topics on Siderophore and related natural products biosynthesis

  • Neuroscience of Coffee Part B

    • 1st Edition
    • Volume 289
    • English
    Neuroscience of Coffee, Volume 289 is a pioneering volume that delves into the intricate relationship between one of the world's most beloved beverages and the human brain. Offering a comprehensive exploration of the biochemical and physiological mechanisms underlying coffee's impact on the nervous system, this groundbreaking book transcends traditional coffee literature by focusing specifically on the neurological aspects. Chapters in this new release include Coffee and Parkinson's Disease, Coffee and Alzheimer's Disease, Coffee and Multiple Sclerosis (MS), Coffee and Amyotrophic lateral sclerosis (ALS), Exploring the Complex Relationship Between Caffeine Consumption and Schizophrenia: A Review of Epidemiological and Clinical Studies, and much more.Additional chapters explore Coffee, Antioxidants, and Brain Inflammation, Behavioral and Psychological Aspects of Coffee Consumption, From Bean to Brain: Coffee, Gray Matter, and Neuroprotection in Neurological Disorders Spectrum, and Synaptic Modulation by Coffee Compounds: Insights into Neural Plasticity.

  • Critical Heart Condition During Pregnancy

    Critical Care Obstetrics
    • 1st Edition
    • Jorge Hidalgo + 2 more
    • English
    Critical Heart Condition During Pregnancy, a volume in the Critical Care Obstetrics series, provides a novel reference to educate physicians, nurses, and all allied healthcare personnel caring for pregnant women with various health compromises specific to cardiac complications. The book's chapters reflect the growing scope of critical care obstetrics and the increasing importance and recognition of the hospital structure's field. All intensivists, regardless of primary discipline, must possess a core set of critical care skills that allow them to manage critically ill patients. The authors have gathered the best evidence-based material explicitly focused on cardiac scenarios.This volume presents cardiac medical-surgical complications that any patient can present during and post-partem, such as Arrhythmias, Endocarditis, Cardiogenic Shock, heart failure, and more.

  • Environmental Challenges in Attaining Food Security

    • 1st Edition
    • Volume 9
    • English
    Environmental Challenges in Attaining Food Security, Volume Nine in the Advances in Food Security and Sustainability series, highlights new advances in the field, with this new volume presenting interesting chapter on important topics such as Exacerbation of Food Insecurity in Africa: A Consequence of the Dual Threat of COVID-19 and the Russia-Ukraine Crisis; Rising Environmental Issues: A hindrance to food security; Microplastics in Soil and Water: Unveiling Environmental Risks and Implications; Emerging Contaminants – Categorization, Effect and Treatment; The Potential Impact on Pesticides on Insect Pollinators and Their Ecological Implications, and much more.Additional chapters cover Change in geo-environmental conditions and crop productivity; Pesticide Concentration and Its Impacts: Food security Vs. Food safety; Heavy metals in soil and water: Sources, fate, toxicology and remediation; Salinity stress in Crop Plants: Effects and Eco-friendly management; Salinity Stress: Impact on Plant Growth; Micronutrient bioavailability in contaminated soil and mitigation strategies for toxicity; Decrease in Arable Land and Water; and Nano-enabled sensor modules for detection of agrochemicals in diverse soil, and water systems: Progression and future trends; Monoculture Of Crops.

  • Microbiome and Nano-Cross-Talk

    Sustainable Agriculture and Beyond
    • 1st Edition
    • Kanchan Vishwakarma + 2 more
    • English
    Microbiome Nano-Cross-Talk: Sustainable Agriculture and Beyond presents a comprehensive overview of the functional aspects of multiphasic microbial and nanotechnological interactions within and between plants and their ecosystem. Recognizing that beneficial microbes are involved in plant growth promotion, this book highlights their mechanism and regulation to enhance plant’s yield and development even under stressed conditions. The merging of nanotechnology with microbiology is an essential aspect of this book. Various nanomaterials, their synthesis approaches as well as applications in agriculture have been studied extensively in past years.With a focus on focus the morphological, anatomical, biochemical, molecular and gene expression levels of plant growth promotion, the book is the first of its kind to enable scientists to unravel the different pathways and signaling cascades involved in response to this interaction and to understanding how nanomaterials regulate the plant-microbe associations. It critically examines the role of beneficial microbes in conjunction with nanoparticles in plants and the mechanisms adopted by the plants at the biochemical and molecular levels to enhance plant growth and mitigate various stresses.

  • OrthoBiologics

    • 1st Edition
    • Rachel M. Frank + 2 more
    • English
    OrthoBiologics provides state-of-the-art knowledge of current biologic therapies for a variety of orthopaedic conditions in a single source. The content is presented in a straightforward manner, including defining all currently available orthobiologic options, discussing processing characteristics and appropriate clinical use, and finally, summarizing clinical applications and outcomes as well as future potential directions.In addition to covering current approaches and applications, the editors aim for this book to present “best practices” for those practicing and researching orthopaedic pathologies and orthobiologic treatments, including blood and cellular based therapies. The editors are world-renown experts in the field and this book fills a gap in the market.

  • Neuroscience of Coffee Part A

    • 1st Edition
    • Volume 288
    • English
    The Neuroscience of Coffee is a pioneering volume that delves into the intricate relationship between one of the world's most beloved beverages and the human brain. Offering a comprehensive exploration of the biochemical and physiological mechanisms underlying coffee's impact on the nervous system, this groundbreaking book transcends traditional coffee literature by focusing specifically on the neurological aspects. From deciphering the molecular intricacies of caffeine to examining the complex interactions within the nervous system, the volume provides an unprecedented insight into how coffee influences brain function, mental health, and neurodegenerative diseases. It addresses the growing interest in understanding everyday dietary choices and their neurological implications, filling a crucial gap in accessible yet detailed resources. This book not only contributes to the evolving field of neuroscience but also serves as a valuable guide for professionals, students, and informed laypersons seeking a deeper understanding of coffee's effects on brain health and overall well-being.

  • Comprehensive Hematology and Stem Cell Research

    • 1st Edition
    • Nima Rezaei
    • English
    **2025 PROSE Award Category Winner in Clinical Medicine**Comprehens... Hematology and Stem Cell Research is the first major reference to cover both stem cell research and therapy as well as the range of hematological disorders they are currently used to treat and may potentially be able to treat in the future. This five volume set includes fundamentals, such as the underlying mechanisms of the blood and immune system, highlighting blood disorders and cancers of the blood, including lymphoma, leukemia, and myeloma. Other sections cover stem cell research and therapy, from harvesting stem cells to their utilization in cancer treatments.Finally, the work looks to the future and explores newer stem cell research that may lead to future treatments. This book is an excellent resource for students at the graduate and post-graduate levels, academics, and researchers in the fields hematology, immunology and oncology.

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