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Books in Life sciences

  • Neurocritical Care, An Issue of Neurologic Clinics

    • 1st Edition
    • Volume 43-1
    • November 18, 2024
    • Alejandro A. Rabinstein
    • English
    In this issue of Neurologic Clinics, guest editor Dr. Alejandro A. Rabinstein brings his considerable expertise to the topic of Neurocritical Care. Top experts cover key topics in the field, including ICU delirium: a neurological perspective; prolonged monitoring of brain electrical activity in the ICU; AI applications in neurocritical care; brain injury after cardiac arrest: refining prognosis; advances in the critical care of ischemic brain infarction; and many more.

  • The Three Functional States of Proteins

    Structured, Intrinsically Disordered, and Phase Separated
    • 1st Edition
    • November 17, 2024
    • Timir Tripathi + 1 more
    • English
    The Three Functional States of Proteins explores how structured proteins, intrinsically disordered proteins, and phase separated proteins contribute to the complexity of cellular life, and offers insights into their roles in both health and disease. It discusses the latest research findings and highlight groundbreaking discoveries and innovative methodologies used to study these protein states.Traditionally... the different states of proteins have been defined based on their structures and functions. However, it is becoming increasingly clear that these criteria alone may not be sufficient to capture the complex and multifaceted properties of these molecules. Definitions based on thermodynamics and kinetics are now recognized as potentially more appropriate for comprehensively understanding protein states. Emerging evidence indicates that under physiological conditions, a majority of proteins possess the capability to exist in and transition between the native, droplet, and amyloid states. These distinct states play crucial roles in various cellular functions, influenced significantly by their physicochemical and structural properties. The book also considers the interactions among these states and discusses how their internal organization as individual molecules, as well as their collective organization as molecular assemblies are stabilized. Furthermore, it examines the processes by which these states are formed and the cellular functions associated with each specific state.

  • Sustainable Management of Agro-Food Waste

    Fundamental Aspects and Practical Applications
    • 1st Edition
    • November 17, 2024
    • Shalini Rai + 2 more
    • English
    Sustainable Management of Agro-Food Waste: Fundamental Aspects and Practical Applications provides insights into the latest approaches for optimizing waste produced by these industries. Bioconversion of agro-food waste is a significant concern for maintaining the ecosystem. This book covers current research into the production of a variety of bioactive compounds, bioenergy resources, and nanomaterials using potential microbes associated widely with the industry’s waste. With primary focus on the microbial enzymes, secondary metabolites, single cell protein, bioethanol, biohydrogen, bio-fortified compost, bioelectricity, and nanomaterial’s, the book presents a range of biotechnological approaches.Sections describe the application of microbial niches in waste recycling and renewable energies like biofuel, plant enzymes, and hormones for different agriculture and allied sectors. With recent advancements in the synthesis of bioactive compounds, bioenergy, and nanomaterials and the discovery of their agriculture, environmental and biomedical applications, it is expected that these methods will be applied at a large scale for industrial application in different sectors. Policies required for the agro-food waste management and option for their utilization are also discussed, along with the sources of their generation.

  • Yoga for Cardiovascular Disease and Rehabilitation

    Integrating Complementary Medicine into Cardiovascular Medicine
    • 1st Edition
    • November 17, 2024
    • Indranill Basu Ray
    • English
    Yoga in Cardiovascular Disease and Rehabilitation: Integrating Complementary Medicine into Cardiovascular Medicine highlights recent research, clinical trials and experiments on yoga and meditation as a preventative measure against various major cardiovascular diseases, including hypertension, hyperlipidemia, coronary artery disease and metabolic syndromes.Chapters discuss yoga's role in ameliorating cardiac dysfunction and current knowledge on the effects of yoga on the brain, emotion, and other factors that initiate and perpetuate vascular inflammation. Cellular, genetic, and molecular effects of yoga based on experimental evidence are also covered in detail, providing readers with the latest research on the effects of yoga and meditation in heart diseases.This book also explores current knowledge gaps in yoga research to facilitate further research and is a comprehensive reference to scientists and clinicians interested in yoga's health effects, including preventing and treating diseases.

  • Leveraging Metaverse and Analytics of Things (AoT) in Medical Systems

    • 1st Edition
    • November 16, 2024
    • D. Jude Hemanth + 1 more
    • English
    Leveraging Metaverse and Analytics of Things (AoT) in Medical Systems explores the potential benefits and applications of emerging technologies such as metaverse and AoT in the field of healthcare. The book provides insights into how these technologies can be leveraged to improve the efficiency, effectiveness, and quality of medical systems. It explores the concept of metaverse and its potential applications in healthcare, including the use of virtual and augmented reality technologies for medical education, training, and simulation, as well as the development of immersive environments for patient care and therapy.The book also delves into the field of AoT, such as the use of wearable devices, smart sensors, and other connected technologies. Applications to monitor patient health, track medical outcomes, and inform clinical decision-making are covered. Integrating both technologies can help improve medical training, diagnosis, treatment, and patient outcomes through the use of virtual reality and real-time data analytics.

  • Vagus Nerve Stimulation

    • 1st Edition
    • November 16, 2024
    • Peter Staats + 3 more
    • English
    In the complex realm of our physiology, the vagus nerve stands as a silent orchestrator, influencing health and disease in ways that have long been underestimated. Vagus Nerve Stimulation delves into the profound significance of this 10th cranial nerve, tracing its course through the body and illuminating its role as a vital component of the parasympathetic nervous system.This comprehensive reference, contributed by leading experts at the forefront of medical science, unveils the groundbreaking field of vagus nerve stimulation—a non-invasive approach to harness the body's innate potential for health optimization, inflammation control, and disease modification. Contributed by leading experts in the field, this comprehensive volume serves as a compendium of current knowledge about stimulating the vagus nerve in many different disease states. This book starts with the foundational insights in Basic Science and Technical Considerations. From there, it continues to Neurologic Conditions, where chapters explore applications for epilepsy, cluster headaches, and concussions. Evolving Therapy for Neurologic Conditions introduces cutting-edge treatments for acute ischemic stroke, synaptic plasticity, and neurodegenerative disorders. The book extends into Psychiatric and Somatic Conditions, providing insights into anxiety, depression, addiction disorders, and more. Conventional Inflammatory Conditions shed light on vagus nerve stimulation's role in combatting sepsis, immune-mediated inflammatory diseases, and metabolic syndrome, among others. Concluding with a foray into Oncology, the book highlights the potential of vagus nerve stimulation in addressing the lingering effects of long covid and migraine. With an authoritative blend of scientific rigor and practical application, this reference serves as an indispensable guide to the vast landscape of vagus nerve stimulation, transforming our understanding of health and wellness.

  • Nonclinical Development of Biologics, Vaccines and Specialty Biologics

    • 2nd Edition
    • November 16, 2024
    • Lisa M. Plitnick + 1 more
    • English
    Nonclinical Development of Biologics, Vaccines and Specialty Biologics, Second Edition, is a complete reference devoted to the nonclinical safety assessment of novel biopharmaceuticals, vaccines, cell and gene therapies, and oncology therapeutics. Updated and revised, the new edition compares and contrasts these types of biologics with one another and with small molecule drugs, while incorporating the most current and essential international regulatory guidelines. This book discusses the different types of biologics, as well as early characterization strategies, principles of study design, nonclinical pharmacokinetics and pharmacodynamics, nonclinical assays, and regulatory guidelines. A coedited book with chapters authored by leading experts in the field, this comprehensive reference provides critical insights to all researchers involved in early through late-stage biologics.

  • Neglected Zoonoses and Antimicrobial Resistance

    Impact on One Health and Sustainable Development Goals
    • 1st Edition
    • November 16, 2024
    • Indranil Samanta + 2 more
    • English
    Neglected Zoonoses and Antimicrobial Resistance: Impact on One Health and Sustainable Development Goals provides a thorough examination of how neglected zoonoses and antimicrobial resistance together hinder the achievement of sustainable development goals declared by the United Nations in the pursuit of a disease-free world. Neglected zoonotic diseases, as defined by the World Health Organization, are diseases likely to impact the livelihoods of livestock keepers and those living in periurban communities in developing countries. This book examines how such zoonoses affect the health of vulnerable farming populations and reduce the production capacity of their livestock.Written by internationally recognized experts in the field of livestock and poultry zoonoses, this book provides the reader with a comprehensive description of modern sustainable development goals and defines neglected zoonotic diseases and their impacts on human physical, mental, social, and economic health. Subsequent chapters systematically describe the epidemiology, hosts and transmission, disease process, economic significance, and prevention and treatment protocols of key neglected zoonotic diseases, including echinococcosis, leishmaniasis, zoonotic tuberculosis, anthrax, brucellosis, leptospirosis, borreliosis, rickettsioses, and rabies. The book concludes with an assessment of the obstacles to achieving Sustainable Development Goals and possible mitigation strategies for veterinary researchers and policymakers alike.

  • Diagnosing Musculoskeletal Conditions using Artificial Intelligence and Machine Learning to Aid Interpretation of Clinical Imaging

    • 1st Edition
    • November 16, 2024
    • Rakesh Kumar + 3 more
    • English
    Bone deformations can lead to musculoskeletal disorders and negatively impact on individual quality of life. Early and accurate detection of bone deformation is crucial for effective medical intervention. Diagnosing Musculoskeletal Conditions Using Artificial Intelligence and Machine Learning to Aid Interpretation of Clinical Imaging outlines a comprehensive approach that integrates Artificial Intelligence (AI) and Machine Learning (ML) techniques to identify bone deformations promptly and accurately. By leveraging advanced image analysis and pattern recognition, this approach aims to revolutionize the field of orthopedic diagnostics. This book covers challenges, technologies, applications, and future trends of AI and ML in Bone Deformation, addressing advanced and innovative techniques, frameworks, methodologies, and practical implementations of machine learning to get early predictions of Bone deformation. Written by experts in the field for researchers, surgeons, students, and instructors interested in musculoskeletal conditions.

  • Transfusion Medicine and Hemostasis

    Clinical and Laboratory Aspects
    • 4th Edition
    • November 16, 2024
    • Beth H. Shaz + 3 more
    • English
    **Selected for 2025 Doody’s Core Titles® in Laboratory Medicine**Transfusio... Medicine and Hemostasis: Clinical and Laboratory Aspects, Fourth Edition continues to be the only "pocket-size" quick reference for pathology and transfusion medicine for residents and fellows. It is helpful to all physicians and allied health professionals who order and administer blood components, cellular therapies, specialized factors for hemostatic abnormalities, coagulation testing, and those who consult and care for these often very ill patients. This book is ideal for pathology, medicine, surgery, and anesthesia residents, transfusion, hematology, and anesthesia fellows, and certified and specialized practitioners, as well as medical technologist in transfusion, cellular therapy, hematology, and coagulation. This new edition covers the many new developments that have occurred since the previous edition to include new blood products, new indications, or clinical conditions in which blood products are used. Similarly, new hemostasis testing is introduced as well as new clinical scenarios due the COVID-19 pandemic that area relevant to hemostasis and transfusion medicine. This includes COVID coagulopathy, Vaccine Induced Thrombotic Immune Thrombocytopenia, Pediatric reference range in coagulation testing, Platelet rich plasma and MNC products – CAR-T cells.

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