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Elsevier

Books in Neuroscience

Elsevier's Neuroscience collection empowers educators, researchers, and students with actionable knowledge to drive collaborative research and advancements in the field. Content covers the nervous system's intricate workings, covering branches like Affective, Behavioral, and Cognitive neuroscience to investigate the neural basis of emotions, behavior, and cognitive functions. Spanning from Molecular and Cellular Neuroscience to Developmental Neuroscience, content provides insights into brain function in health and disease.

  • Neuromonitoring Techniques

    Quick Guide for Clinicians and Residents
    • 1st Edition
    • Hemanshu Prabhakar
    • English
    Neuromonitoring Techniques: Quick Guide for Clinicians and Residents provides a quick and easy guide to understanding various neuromonitoring equipment. Chapters include intracranial pressure monitoring, EEG-based monitors, evoked potentials and transcranial doppler. This book is written for trainees, clinicians and researchers in the fields of neurosurgery, neurocritical care, neuroradiology, neuroanesthesia and neurology. As specialized neuromonitoring is now routinely done in neurosurgical cases, it provides an important resource for neurologists, neurophysiologists, anesthesiologists and residents who are expected to have theoretical and practical knowledge on different systems. Each monitoring system is discussed separately, with examples, images, reference values and their interpretations.

  • Handbook of Neuroemergency Clinical Trials

    • 2nd Edition
    • Brett E. Skolnick + 1 more
    • English
    Handbook of Neuroemergency Clinical Trials, Second Edition, focuses on the practice of clinical trials in acute neuroscience populations, or what have been called neuroemergencies. Neuroemergencies are complex, life-threatening diseases and disorders, often with devastating consequences, including death or disability. The overall costs are staggering in terms of annual incidence and costs associated with treatment and survival, yet despite their significance as public health issues, there are few drugs and devices available for definitive treatment. The book focuses on novel therapies and the unique challenges their intended targets pose for the design and analysis of clinical trials. This volume provides neurologists, neuroscientists, and drug developers with a more complete understanding of the scientific and medical issues of relevance in designing and initiating clinical development plans for novel drugs intended for acute neuroscience populations. The editors provide the best understanding of the pitfalls associated with acute CNS drug development and the best information on how to approach and solve issues that have plagued drug development.

  • Reasoning

    The Neuroscience of How We Think
    • 1st Edition
    • Daniel Krawczyk
    • English
    Reasoning: The Neuroscience of How We Think is a comprehensive guide to the core topics related to a thorough understanding of reasoning. It presents the current knowledge of the subject in a unified, complete manner, ranging from animal studies, to applied situations, and is the only book available that presents a sustained focus on the neurobiological processes behind reasoning throughout all chapters, while also synthesizing research from animal behavior, cognitive psychology, development, and philosophy for a truly multidisciplinary approach. The book considers historical perspectives, state-of-the-art research methods, and future directions in emerging technology and cognitive enhancement. Written by an expert in the field, this book provides a coherent and structured narrative appropriate for students in need of an introduction to the topic of reasoning as well as researchers seeking well-rounded foundational content. It is essential reading for neuroscientists, cognitive scientists, neuropsychologists and others interested in the neural mechanisms behind thinking, reasoning and higher cognition.

  • The Role of Neuropeptides in Addiction and Disorders of Excessive Consumption

    • 1st Edition
    • Volume 136
    • English
    The Role of Neuropeptides in Addiction and Disorders of Excessive Consumption, Volume 136 in the International Review of Neurobiology series, provides an overview of the top candidate neuropeptides in the modulation of alcohol and drug abuse, also covering eating disorders and obesity. Topics covered in this latest release include Corticotropin Releasing Factor (CRF) and Addictive Behaviors, Dynorphin/Kappa Opioid Receptor Signaling in Pre-clinical Models of Alcohol, Drug, and Food Addiction, The Role of Ghrelin Signaling in Additive Behaviors, The Role of the Melanocortin System in Drug and Eating Disorders, Substance P and the Neurokinin-1 Receptor: The New CRH, and the Role of Neuropeptide Y (NPY) in Drug and Eating Disorders. The book uniquely highlights the overlapping central mechanisms that contribute to both drug and alcohol abuse and eating disorders.

  • Neuropathology

    • 1st Edition
    • Volume 145
    • English
    Neuropathology, Volume 145, the latest release in the Handbook of Clinical Neurology series, includes all the major topics found in a typical neuropathology text, but differentiates itself by providing a thorough overview of the morphological background of neurological disorders for researchers and clinicians who do not specialize in pathology or its clinicopathological aspects. This volume offers strong coverage of brain imaging and advances in molecular pathology and genetics, and is particularly timely given the amount of neuropathological research currently taking place.

  • Role of the Mediterranean Diet in the Brain and Neurodegenerative Diseases

    • 1st Edition
    • Tahira Farooqui + 1 more
    • English
    Role of the Mediterranean Diet in the Brain and Neurodegenerative Disease provides a comprehensive overview of the effects of all components of the Mediterranean diet on the brain, along with its beneficial effects in neurodegenerative diseases. It covers topics on neurodegenerative diseases (Alzheimer disease (AD), Parkinson disease, (PD) Huntington disease (HD) and Amyotrophic Lateral Sclerosis (ALS), also providing information on how cardiovascular disease, Type 2 Diabetes, and Metabolic Syndrome become risk factors for neurodegenerative diseases. This book focuses on how the Mediterranean diet suppresses oxidative stress and neuroinflammation in neurodegenerative diseases as well as signal transduction. The Mediterranean diet is characterized by the abundant consumption of olive oil, high consumption of plant foods (fruits, vegetables, pulses, cereals, nuts and seeds); frequent and moderate intake of wine (mainly with meals); moderate consumption of fish, seafood, yogurt, cheese, poultry and eggs; and low consumption of red meat and processed meat products. High consumption of dietary fiber, low glycemic index and glycemic load, anti-inflammatory effects, and antioxidant compounds may act together to produce favorable effects on health status. Collective evidence suggests that Mediterranean diet not only increases longevity by lowering cardiovascular disease, inhibiting cancer growth, but also by protecting the body from age-dependent cognitive decline.

  • The Neurobiology of Brain and Behavioral Development

    • 1st Edition
    • Robbin Gibb + 1 more
    • English
    The Neurobiology of Brain and Behavioral Development provides an overview of the process of brain development, including recent discoveries on how the brain develops. This book collates and integrates these findings, weaving the latest information with core information on the neurobiology of brain development. It focuses on cortical development, but also features discussions on how the other parts of the brain wire into the developing cerebral cortex. A systems approach is used to describe the anatomical underpinnings of behavioral development, connecting anatomical and molecular features of brain development with behavioral development.The disruptors of typical brain development are discussed in appropriate sections, as is the science of epigenetics that presents a novel and instructive approach on how experiences, both individual and intergenerational, can alter features of brain development. What distinguishes this book from others in the field is its focus on both molecular mechanisms and behavioral outcomes. This body of knowledge contributes to our understanding of the fundamentals of brain plasticity and metaplasticity, both of which are also showcased in this book.

  • Brain Research in Addiction

    • 1st Edition
    • Volume 235
    • English
    Brain Research in Addiction, Volume 235, the latest volume in this groundbreaking series on addiction, presents the neurobiological, pathological, cognitive and evolutionary aspects of addiction, with new chapters covering the Neurobiology of drug intake escalation, the Role of the orexinergic system in reward, Mental time travel and addictive behaviors, An evolutionary perspective on addiction- Addiction is the price we pay for innovation and adaptability, and how Cocaine exposure affects object-place recognition memory in non-human primates. Chapters in this serial are presented by leading researchers from North America, South America, Europe, Africa, Asia and Australia, who present addiction research from the bottom up, including how addiction evolved, basic research on animal models, and the psychiatric, psychological and cognitive characteristics of addictive behaviors in humans.

  • Sport and the Brain: The Science of Preparing, Enduring and Winning, Part B

    • 1st Edition
    • Volume 234
    • English
    Sport and the Brain: The Science of Preparing, Enduring and Winning, Part B, Volume 233 reflects recent advancements in the understanding of how elite athletes prepare for, and perform at, peak levels under the demands of competition. Topics discussed in this new release include a section on Exploring the Applicability of the Contextual Interference Effect in Sports Practice, The Resonant System: Linking Brain-body-environme... in Sport Performance, the Effects of Acute High-intensity Exercise on Cognitive Performance in Trained Individuals: A Systematic Review, Moving Concussion Care to the Next Level: The Emergence and Role of Concussion Clinics in the UK, and Neurocognitive Mechanisms of the Flow State. This longstanding series takes a multidisciplinary approach, focusing on aspects of psychology, neuroscience, skill learning, talent development and physiology.

  • Functional Connectivity, An Issue of Neuroimaging Clinics of North America

    • 1st Edition
    • Volume 27-4
    • Jay J. Pillai
    • English
    This issue of Neuroimaging Clinics of North America focuses on Functional Connectivity, and is edited by Dr. Jay Pillai. Articles will include: Applications of rs-fMRI to presurgical mapping: sensorimotor mapping; Dynamic functional connectivity methods; Machine learning applications to rs-fMRI analysis; Frequency domain analysis of rs-fMRI; Applications of rs-fMRI to epilepsy; Data-driven analysis methods for rs-fMRI; Applications of rs-fMRI to presurgical mapping: language mapping; Limitations of rs-fMRI in the setting of focal brain lesions; Applications of rs-fMRI to neuropsychiatric disease; Applications of rs-fMRI to Traumatic Brain Injury; Applications of rs-fMRI to neurodegenerative disease; Graph theoretic analysis of rs-fMRI; and more!

  • Neurocritical Care, An Issue of Neurologic Clinics

    • 1st Edition
    • Volume 35-4
    • Alejandro A. Rabinstein
    • English
    This issue of Neurologic Clinics, edited by Dr. Alejandro A. Rabinstein, will cover Neurocritical Care. Topics include, but are not limited to: Anoxic Brain Injury; Treatment of Intracranial Hypertension; Management of Traumatic Brain Injury; Cortical Spreading Depression and Ischemia in Neurocritical Patients; Temperature Control in Acute Brain Injury; HSV Encephalitis; Primary Acute Neuromuscular Respiratory Failure; ICU-Acquired Weakness; Emergency and Critical Care Management of Intracerebral Hemorrhage; New developments in Refractory Status Epilepticus; Acute Cardiac Complications in Critical Brain Disease; Nosocomial Infections in Neurocritical Patients; Neurological Complications after Solid Organ Transplantation; and Shared Decision Making in the NICU.

  • Arachnoid Cysts

    Clinical and Surgical Management
    • 1st Edition
    • Knut Wester
    • English
    Arachnoid Cysts: Clinical and Surgical Management gives a broad and updated presentation of the condition, including symptomatology, diagnostics, management and treatment. The book covers the effects of surgical treatment on clinical symptoms and the effects cysts have on cognition, as well as cognitive improvement after surgical cyst decompression. This book is written for researchers, residents and clinical practitioners in clinical neuroscience, neurology, neurosurgery, neuroradiology and pediatrics.

  • Arachnoid Cysts

    Epidemiology, Biology, and Neuroimaging
    • 1st Edition
    • Knut Wester
    • English
    Intracranial arachnoid cysts are congenital malformations with a predilection for the middle cranial fossa and an estimated prevalence in the general population as high as 1.7%. The common assumption is that these cysts are incidental findings and the symptoms associated with them are not caused by the cyst and consequently, that surgical intervention will not benefit the patient. However, there is now a growing understanding reflected in the international literature among neurologists and neurosurgeons that arachnoid cysts do harm and that the patients’ complaints can be relieved by surgical treatment. Arachnoid Cysts: Epidemiology, Biology, and Neuroimaging gives a broad and updated presentation of the condition, including epidemiology, etiology, biology (including genetics and molecular biology), and neuroimaging of same. This book is written for researchers, residents, and clinical practitioners in clinical neuroscience, neurology, neurosurgery, neuroradiology, and pediatrics.

  • Finding the Nerve

    The Story of Impedance Neurography
    • 1st Edition
    • Philip C Cory
    • English
    Finding the Nerve: The Story of Impedance Neurography discusses research that elucidates the nature of nerve simulation via externally applied electrical fields, and how it has led to an entirely new understanding of neuronal cell membrane biophysics and defined a novel nerve imaging technology. It details how these discoveries came about and the nature of research that derives from unexplained clinical observations. The primary technology, impedance neurography, is a wholly new way of nerve-specific visualization in 2-D or 3-D, with the ability to define both normal and abnormal functioning of nerves, heretofore unavailable from techniques such as MRI neurography. This is of particular importance with respect to the obesity epidemic where physicians performing nerve-related procedures cannot use ultrasound visualization due to the depth limitations of that technology.

  • Environmental Causes and Prevention Measures for Alzheimer’s Disease

    • 1st Edition
    • George J. Brewer
    • English
    Environmental Causes and Prevention Measures for Alzheimer’s Disease examines the increased incidence of the disease in developed countries and aims to educate neuroscientists, medical practitioners and other educated individuals on new insights into environmental causation, primarily metals. This book looks into the web of evidence around the hypothesis of copper toxicity and the additional role that a high fat diet plays in disease progression and cognition loss. The data and its implications are discussed, along with potential prevention measures. This book will generate excitement and interest among neuroscientists, medical practitioners and other biomedical researchers.

  • SPEC – Handbook of Clinical Neurology, Volume 144, Huntington Disease, 12-Month Access, eBook

    • 1st Edition
    • Volume 144
    • English
    Huntington Disease summarizes the most recent findings related to the disease, providing both cutting edge coverage for clinical/research specialists looking to expand their knowledge base of Huntington disease information, as well as solid groundwork for advanced students from various backgrounds (neurology, psychiatry, neuropsychology, genetics). The volume includes all major areas of Huntington disease clinical care and research, whereas many other HD texts focus solely on neurological symptoms. This book also addresses behavioral and cognitive symptoms, brain imaging, and family dynamics and therapeutic alliances in working with individuals affected by HD. Clinical trials are covered extensively, including design considerations for therapeutic studies. The devastating nature of Huntington’s disease is well appreciated throughout the neuroscience, neurology, and psychiatric communities, and a great amount of basic and clinical research is currently taking place. However, much of that occurs in isolated research silos, and it is critical that an interdisciplinary resource be developed to provide in depth information to enhance communication and collaboration. This volume in the Handbook of Clinical Neurology series is that resource.

  • Neuroepidemiology in Tropical Health

    • 1st Edition
    • Pierre-Marie Preux + 1 more
    • English
    Neuroepidemiology in Tropical Health covers major neurological diseases of relevance in tropical settings and examines the specificities of epidemiology of neurological diseases in the context of tropical countries that face many challenges when compared to the developed world. Part One focuses on methods and their eventual specificities, and how such methods, like sampling, can be adapted for specific scenarios. Parts Two and Three discuss environmental factors and their consequences for neurology in the tropical world, as well as large geographical areas and their specificities. Finally, Part Four presents relevant neurological diseases in in-depth chapters. This invaluable information will help readers recognize the various neurological conditions presented, with the inclusion of their aetiologies and treatment in tropical areas. The book therefore fills a gap in the neuroepidemiology literature, with chapters written by an international collection of experienced authors in the field.

  • Environmental Factors in Neurodegenerative Diseases

    • 1st Edition
    • Volume 1
    • English
    Environmental Factors in Neurodegenerative Diseases, Volume One addresses contemporary advances in neurotoxicology, with thematic volumes providing authoritative review articles on key issues in the field. Updates in this new volume include chapters on Air pollution and neurodegenerative diseases, Mercury and Parkinson’s disease, Pesticides and PD: current evidence, Aluminum and neurodegeneration, Microglia and neurodegeneration, Dietary factors, Mitochondria in neurodegeneration, and Manganese and neurodegeneration. Edited by leading experts, volumes are designed as in-depth overviews of the latest topic developments that analyze the effect of varied chemical agents on the nervous system. It is an essential resource for researchers and graduate students alike.

  • Computational Psychiatry

    Mathematical Modeling of Mental Illness
    • 1st Edition
    • Alan Anticevic + 1 more
    • English
    Computational Psychiatry: Mathematical Modeling of Mental Illness is the first systematic effort to bring together leading scholars in the fields of psychiatry and computational neuroscience who have conducted the most impactful research and scholarship in this area. It includes an introduction outlining the challenges and opportunities facing the field of psychiatry that is followed by a detailed treatment of computational methods used in the service of understanding neuropsychiatric symptoms, improving diagnosis and guiding treatments. This book provides a vital resource for the clinical neuroscience community with an in-depth treatment of various computational neuroscience approaches geared towards understanding psychiatric phenomena. Its most valuable feature is a comprehensive survey of work from leaders in this field.

  • Chordomas and Chondrosarcomas of the Skull Base and Spine

    • 2nd Edition
    • Griffith R. Harsh IV + 1 more
    • English
    Chordomas and Chondrosarcomas of the Skull Base and Spine, Second Edition, is a major reference and guide for neurosurgeons, medical oncologists, neuroscientists, orthopedic surgeons, head and neck surgeons and radiation oncologists that treat patients and research chordomas and chondrosarcomas of the axial skeleton. This book is the unique result of the collaboration of multidisciplinary specialists from a wide variety of fields (neurological sciences, medical oncology, molecular biology, orthopedics and radiation oncology), offering the most relevant information about chordomas and chondrosarcomas of the axial skeleton from each of these fields condensed into one single volume. It contains new medical knowledge and scientific advances regarding the treatment of these types of tumors. Additionally, the book includes chapters written by the Chordoma Foundation and Sarcoma Foundation of America, providing the most valuable information and support for patients and their relatives.

  • The Complex Connection between Cannabis and Schizophrenia

    • 1st Edition
    • Michael T. Compton + 1 more
    • English
    The Complex Connection between Cannabis and Schizophrenia provides an in-depth overview of the current state of research into the role that cannabis plays in schizophrenia, covering both the pathophysiological and the pharmacological implications. It addresses the epidemiology of cannabis use and the risks associated with its use, the biological aspects of the drug, its effects on the brain and the pharmacological possibilities of using cannabidiol to treat schizophrenia. It is the only book on the market devoted exclusively to examining the links between this very commonly used (and misused) drug and a specific set of devastating psychiatric illnesses, providing a comprehensive guide to our current understandings of this relationship. Marijuana is the most commonly used illicit drug globally, and is becoming increasingly decriminalized and even legalized worldwide. Among the numerous mental-health concerns related to the drug, there is mounting evidence of an intricate link between cannabis use and schizophrenia and related psychotic disorders. At the same time, there is promising evidence to suggest that cannabidiol, one of the many compounds found in cannabis that activates the brain’s cannabinoid receptors, could prove to be an effective antipsychotic to treat schizophrenia.

  • Vital Models

    The Making and Use of Models in the Brain Sciences
    • 1st Edition
    • Volume 233
    • English
    The use of models has been important to the historical and contemporary study of the human brain, yet very little study by social scientists has been dedicated to how the brain sciences develop and use models to better understand what brains are and how they work, including the complex entanglements between brains, bodies and their environments. Vital Models: The Making and Use of Models in the Brain Sciences explores the history and use of brain models from clinical psychiatry to psychopharmacology and cybernetics, as well as developments in digital brain modeling, simulation, imaging and connectomics. This timely volume helps both scientists and students better understand the variety, strengths, weaknesses and applicability of models in neuroscience.

  • Neurobiology of Chinese Herb Medicine

    • 1st Edition
    • Volume 135
    • English
    Neurobiology of Chinese Herb Medicine, Volume 135 is a valuable book for anyone interested in alternative medicine or the scientific research surrounding ancient herbal medicine. This updated volume in the series includes chapters that delve into timely topics, including the Effects of Lycium Barbarum on the Visual System, the Effect of Chinese Herbal Medicine on Alzheimer’s Disease, the Effect and Mechanism of Chinese Herbal Medicine on Parkinson’s Disease, the Neurobiology of Chinese Herbal Medicine on Major Depressive Disorder, the Treatment of Insomnia with Traditional Chinese Herbal Medicine, and the Metabolic Factors and Adult Neurogenesis: Impacts of Chinese Herbal Medicine on Brain Repair in Neurological Diseases. This series is ideal for Chinese herbal medicine practitioners who are working in a clinical environment, although the clinical applications of Chinese medicinal herbs presented provide useful references and guidance for any clinical practice that specializes in the treatment of various conditions.

  • Nonmotor Parkinson's: The Hidden Face

    Management and the Hidden Face of Related Disorders
    • 1st Edition
    • Volume 134
    • English
    Non-motor Parkinson's: The Hidden Face-Management and the Hidden Face of Related Disorders, Volume 134, the latest release in the International Review of Neurobiology series, is an up-to-date and comprehensive textbook addressing non-motor aspects of Parkinson’s disease, a key unmet need. Specific chapters in this updated release include Therapeutics and NMS in PD, Non-motor effects of conventional and transdermal therapies in PD, Infusion therapy, CDD and NMS in PD, DBS and NMS in PD, TMS and implications for NMS in PD, Botulinum toxin therapy and NMS in PD, and Nutrition and NMS in PD, amongst others. Including practical tips for non-specialists and clinical algorithms, the book contains contributions from over 40 opinion leaders in the field of movement disorders. It provides practitioners and researchers with a laboratory, to bedside, to caregiver perspective.

  • Nonmotor Parkinson's: The Hidden Face

    The Many Hidden Faces
    • 1st Edition
    • Volume 133
    • English
    Non-motor Parkinson's: The Hidden Face, Volume 133, the first part of the latest volume in the International Review of Neurobiology series, is an up-to-date, comprehensive textbook addressing the non-motor aspects of Parkinson’s disease, a key unmet need. Chapters in this new release include topics such as The hidden face of Parkinson's, JP and non-motor symptoms, Parkinson's: a complex non-motor disease, Neuropathology of NMS of PD, Neurophysiology and animal models related to NMS in PD, Epidemiology of NMS in PD (cohort studies), Genes and NMS in PD, NMS in genetic forms of PD, and Imaging the NMS in PD. Including practical tips for non-specialists and clinical algorithms, this book contains contributions from over 40 opinion leaders in the field of movement disorders, covering the topic from laboratory, to bedside, to caregiver.

  • Comprendre la paralysie cérébrale et les troubles associés

    Évaluations et traitements
    • 2nd Edition
    • Danièle Truscelli + 12 more
    • French
    Comprendre la paralysie cérébrale et les troubles associés est une refonte du livre précédent sur les infirmités motrices cérébrales. Son originalité réside dans le fait qu’il s’engage sur la voie du pronostic autant clinique qu’humain. L’approche médicale est large, de l’atteinte neuromotrice, orthopédique, des troubles de la santé aux facteurs de dysfonctionnement psychologique et/ou neuropsychologique. La recherche d’indices pronostiques dépend d’éléments cliniques déjà validés et s’appuie aussi sur des connaissances scientifiques récentes, comme la plasticité cérébrale.La parole donnée aux adultes en situation de handicap, voire aux familles, permet de suivre la pertinence de l’application des décisions thérapeutiques qu’ils ont vécues. Leurs témoignages indiquent leur dynamique pour trouver une qualité de vie personnalisée et leur volonté de trouver des contacts humains élargis. Des textes complémentaires, des références ainsi que des séquences vidéos montrant les divers aspects de la prise en charge en rééducation et en chirurgie orthopédique sont proposés en ligne. Coécrit par des équipes multidisciplinaires et référentes – médecins de médecine physique et de réadaptation (MPR), pédiatres, chirurgiens, rééducateurs, psychologues, scientifiques –, cet ouvrage a été coordonné par le docteur Danièle Truscelli.

  • Dual Energy CT: Applications in Head and Neck and Neurologic Imaging, An Issue of Neuroimaging Clinics of North America

    • 1st Edition
    • Volume 27-3
    • Reza Forghani + 1 more
    • English
    This issue of Neuroimaging Clinics of North America focuses on Dual Energy CT: Applications in Neurologic, Head and Neck Imaging, and is edited by Drs. Reza Forghani and Hillary R. Kelly. Articles will include: Dual Energy CT: Physical Principles and Approaches to Scanning, Part 1; Dual Energy CT: Physical Principles and Approaches to Scanning, Part 2; Dual Energy CT Applications for Differentiation of Intracranial Hemorrhage, Calcium, and Iodine; Dual Energy CT Angiography of the Head and Neck and Related Applications; Miscellaneous and Emerging Applications of Dual Energy CT for the Evaluation of Intracranial Pathology; Applications of Dual Energy CT for the Evaluation of Head and Neck Squamous Cell Carcinoma; Dual Energy CT Applications for the Evaluation of Cervical Lymphadenopathy; Miscellaneous and Emerging Applications of Dual Energy CT for the Evaluation of Pathologies in the Head and Neck; Dual Energy CT Applications for the Evaluation of the Spine; Applications of Dual Energy CT for Artifact Reduction in the Head, Neck, and Spine; Advanced Tissue Characterization and Texture Analysis using Dual Energy CT: Horizons and Emerging Applications; and more!

  • Clinical Informatics Literacy

    5000 Concepts That Every Informatician Should Know
    • 1st Edition
    • Dean F. Sittig
    • English
    Clinical Informatics Literacy: 5000 Concepts That Every Informatician Should Know is about all aspects of clinical informatics, a subset of the larger field of biomedical informatics. Clinical Informatics is an applied field that exists at the intersection of the fields of medicine, computer science, information science, anthropology, human factors engineering, cognitive psychology and health services research. As such informaticians are required to have an extremely broad understanding of a considerable swath of the fields at the heart of the health-oriented knowledge economy. The author has collected and explained each one of the relevant concepts during his experience of 27 years working with many of the leaders in the field of clinical informatics at several of the leading academic healthcare institutions around the USA. The author’s experience and his didactic approach make this book an essential source of information for all participants in the clinical informatics field.

  • Neurological Problems

    • 1st Edition
    • Jerzy Choróbski
    • English
    Neurological Problems describes the clinical and pathological aspects of numerous neurological disorders. This book is organized into four parts encompassing 69 chapters. The opening part provides an introduction to the close relationship between the central nervous system and the categories of pathological reactions in man. The next parts deal first with certain problems concerning peripheral vasomotor activity, followed by discussions on neurophysiological mechanisms and chemical aspects of neurological problems. The last part presents considerable clinical manifestations and case studies of these problems. This book is of value to neurologists, neurophysiologists, pathologists, and clinicians.

  • Latent Syphilis and the Autonomic Nervous System

    • 2nd Edition
    • Griffith Evans
    • English
    Latent Syphilis and the Autonomic Nervous System, Second Edition describes the link between the pathogenesis of syphilis and the autonomic nervous system. This book is composed of 15 chapters, and begins with a brief introduction to the pathology of syphilis, followed by chapters on the physiologic changes in the thyroid gland, including thyroid enlargement and goiter formation, in early syphilis. The succeeding chapters are devoted to syphilis-related diseases, such as allergy, asthma, vasomotor disturbances, dysphagia, dyspepsia, cancer, and superficial ulceration of the mouth. A chapter describes some clinical features in latent syphilis. The final chapter examines the clinical manifestations of pes cavus, which is both an acquired and congenital disease. This book is of value to pathologists, endocrinologists, clinicians, and medical researchers.

  • A Paradigm Shift to Prevent and Treat Alzheimer's Disease

    From Monotargeting Pharmaceuticals to Pleiotropic Plant Polyphenols
    • 1st Edition
    • Howard Friel + 1 more
    • English
    A Paradigm Shift to Prevent and Treat Alzheimer’s Disease: From Monotargeting Pharmaceuticals to Pleiotropic Plant Polyphenols is the first book to systematically exhibit the powerful pleiotropic pharmacological effects on Alzheimer’s disease of plant-based compounds from ancient foods that humans have been consuming safely with substantial health benefits for thousands of years. These plant-based compounds include curcuminoids from turmeric, resveratrol from red wine and grape seed extract from other grape products, epigallocatechin-gal... (EGCG) from green tea, and oleocanthal and oleuropein from olive oil, in addition to a special extract, EGb 761, from the leaves of Ginkgo biloba, the oldest living species of tree on earth. This book also presents a new analytical framework that convincingly favors a multi-targeting ("pleiotropic") approach to the prevention and treatment of complex chronic diseases, in contrast to the mono-targeting of the pharmaceutical model. A Paradigm Shift to Prevent and Treat Alzheimer’s Disease is a unique and exciting resource for pharmaceutical scientists, pharmacologists, neurologists, general practitioners, research scientists in various medical and life sciences, healthcare professionals in clinical and executive positions, conventional medical schools, schools of naturopathic medicine, healthcare and medical journalists, executives in both national public healthcare systems and private insurers, and informed general readers.

  • Neurobiological Background of Exploration Geosciences

    New Methods for Data Analysis Based on Cognitive Criteria
    • 1st Edition
    • Paolo Dell'Aversana
    • English
    Neurobiological Background of Exploration Geosciences: New Methods for Data Analysis Based on Cognitive Criteria examines the neurobiological background of earth science disciplines. It presents the fundamental features of the human brain that form the cognitive basis of exploration geophysics and investigates how their analysis can drive the development of new brain-based technologies. Crucial aspects of human cognition include the impulse to explore the environment, the ability of our brain to create mental maps and virtual images of the world, and the human ability to recognize, integrate and save patterns of information in a shared memory. Geoscience technology can be made more effective by taking the working neurobiological principles of our brains into account. This book is appropriate for multiple audiences, including neuroscientists, cognitive scientists and geoscientists, presenting both theoretical and experimental results.

  • Nanotechnology Methods for Neurological Diseases and Brain Tumors

    Drug Delivery across the Blood–Brain Barrier
    • 1st Edition
    • Yasemin Gürsoy Özdemir + 2 more
    • English
    Nanotechnology Methods for Neurological Diseases and Brain Tumors: Drug Delivery across the Blood-Brain Barrier compiles the latest (and future potential) treatment strategies for brain tumors and neurological diseases, in particular Alzheimer’s, Parkinson’s and stroke, those that bypass the blood/brain barrier. The current understanding of brain drug delivery and access is discussed in Chapter One, with the next section focusing on the implementation of the nose-to-brain intranasal route in brain-targeted drug delivery. In addition, nanotechnology-based brain drug delivery is covered in Chapter Three. This avenue offers impressive improvement in the treatment of neurological diseases and brain tumors by using bio-engineered systems that interact with biological systems at a molecular level. In Chapter Four, emphasis is placed on the need for brain-targeted experimental models that mimic disease conditions. Final chapters discuss the very latest advances in targeted treatment strategies for neurological diseases and brain tumors.

  • Chronic Traumatic Encephalopathy

    Proceedings of the Boston University Alzheimer’s Disease Center Conference
    • 1st Edition
    • Andrew E. Budson + 4 more
    • English
    Get a thorough, expert overview of the many key facets of chronic traumatic encephalopathy (CTE) with this concise, practical resource by Drs. Andrew E. Budson, Ann C. McKee, Robert C. Cantu, and Robert A. Stern. This easy-to-read reference is based on lectures from Boston University’s Alzheimer’s Disease Center’s November 2016 two-day conference on CTE.

  • Noradrenergic Signaling and Astroglia

    • 1st Edition
    • Nina Vardjan + 1 more
    • English
    Noradrenergic Signaling and Astroglia integrates what is known about the active role of astroglia in the locus coeruleus-noradrener... system and outlines the most recent advances in the field. It discusses the molecular mechanisms underlying norepinephrine-induc... receptor activation in astroglia, cellular metabolism and CNS energy provision, in vitro, ex vivo, and in vivo models, gliosignalling and neuronal activity, and astroglial networks, gap junctions, and morphological plasticity. The book also addresses the role of astroglial adrenergic receptor activation in memory formation, cognition, regulation of sleep homeostasis, and lastly in neurological disorders, including trauma (cellular edema), neurodegeneration (Alzheimer’s disease), and neuroinflammation (multiple sclerosis). Noradrenergic Signaling and Astroglia is a valuable source of new knowledge for a wide audience, including graduate students, post-doctoral fellows, and researchers in neuroscience, life sciences, and the biological and biomedical sciences.

  • Sports Neurology, An Issue of Neurologic Clinics

    • 1st Edition
    • Volume 35-3
    • Tad Seifert
    • English
    This issue of Neurologic Clinics, Edited by Dr. Tad Seifert, will do a comprehensive review of Sports Neurology. Some of the topics discussed in the issue include, but are not limited to: Biomechanical Aspects of Sports-Related Head Injuries; Peripheral Nerve Injuries in Sport; CNS Performance Enhancing Drugs in Sport, Sleep, Recovery, and Performance in Sport; Pathophysiology of Sports-Related Concussion; Neurologic Injuries in Noncontact Sports; Neuropsychological Screening in Concussion; Neurosurgical Emergencies in Sport; Psychiatric Comorbidities in Sport; and Biomarkers and Their Role in Sport-Related Head Trauma, among others.

  • Brain Edema

    From Molecular Mechanisms to Clinical Practice
    • 1st Edition
    • Jerome Badaut + 1 more
    • English
    Brain Edema: From Molecular Mechanisms to Clinical Practice brings together the most widely recognized experts in experimental and clinical brain edema research to review the current knowledge gathered on the molecular and cellular pathophysiology and clinical management of brain edema. This timely book also discusses future directions of research and treatment. Brain edema is an integral and acutely life-threatening part of the pathophysiology of multiple cerebral and non-cerebral disorders, including traumatic brain injury, cerebral ischemia, brain tumors, cardiac arrest, altitude sickness and liver failure. Affecting millions worldwide, research over the past few years has shown that a plethora of complex molecular and cellular mechanisms contribute to this pathological accumulation of water in the brain parenchyma. In parallel, the development of new neuroimaging tools has provided a new way to examine how edema develops longitudinally and in real time, both in pre-clinical models and in patients. Despite intense research over the past few decades, therapeutic options are still limited and sometimes not effective.

  • Engineering Neural Tissue from Stem Cells

    • 1st Edition
    • Stephanie Willerth
    • English
    Engineering Neural Tissue from Stem Cells covers the basic knowledge needed to understand the nervous system and how existing cells can be used to create neural tissue. This book presents a broad range of topics related to the design requirements for engineering neural tissue from stem cells. It begins with the anatomy and function of the central and peripheral nervous system, also covering stem cells, their relation to the nervous system and their function in recovery after injury or disease. In addition, the book explores the role of the extracellular matrix and vasculature/immune system and biomaterials, including their suitability for neural tissue engineering applications.

  • Human Brain in Standard MNI Space

    A Comprehensive Pocket Atlas
    • 1st Edition
    • Juergen K Mai + 1 more
    • English
    Human Brain in Standard MNI Space: A Comprehensive Pocket Atlas is a thorough pocket atlas designed for easy reference and interpretation of medical and scientific MR-images. It is intended for both early career and advanced medical students, for residents in radiology and neurology, and those involved in neuroscience research, emphasizing anatomy’s relationship to radiology. In addition, the book is ideal for non-specialists interested in issues relating to the brain or the determination of imaging features.

  • Rhythmic Stimulation Procedures in Neuromodulation

    • 1st Edition
    • James R. Evans + 1 more
    • English
    Rhythmic Stimulation Procedures in Neuromodulation offers a unique approach to rhythm-related stimulation as it pertains to modulating neural functioning, with the goal of alleviating symptoms of mental disorder. Rhythm and related concepts (frequency, resonance, entrainment) are thought by many to be closely linked to human health and disease. Neurologists and clinical psychologists facilitate neuroplasticity by using pulsed (rhythmic) sensory or electromagnetic stimulation—a group of techniques broadly referred to as neuromodulation. This edited volume describes details of rhythm-related neuromodulation techniques, and experts in the field have detailed the pros and cons of each approach, citing both clinical and scientific support. Each technique chapter provides a detailed description of the procedure, a rationale for application with specific populations, discussion of similarities/differe... relative to other approaches, and support for efficacy. This volume offers readers a historical overview of the roles of rhythm and dysrhythmia in health and disease, including examples of past and present therapeutic uses of rhythmic stimulation, entrainment, and/or modification. It also facilitates speculation about potential developments in rhythm-related methods for the future of mental health. Few books published in the general area of rhythm have focused on the scientific study of the significance of biological rhythms.

  • Institutional Neurosis

    • 2nd Edition
    • Russell Barton
    • English
    Institutional Neurosis is a four-chapter text that systematically presents the dreadful mental changes that may result from institutional life and the steps that can be taken to cure them. The term “institutional neurosis” promotes the syndrome to the category of a disease, rather than a process, thereby encouraging the public to understand, approach, and deal with it in the same way as other diseases. The opening chapter describes the clinical features of the disorder in mental hospitals, its differential diagnosis, etiology, treatment, and prevention. The next chapters consider the etiology or factors associated with institutional neurosis, including apathy, loss of interest, lack of initiative, and sometimes a characteristic posture and gait. The last chapter reviews the various aspects of the treatment of institutional neurosis. This book is of value to neurologists, psychologists, psychiatrists, and researchers in the allied fields.

  • Sport and the Brain: The Science of Preparing, Enduring and Winning, Part A

    • 1st Edition
    • Volume 232
    • English
    Sport and the Brain: The Science of Preparing, Enduring and Winning, Part A, Volume 231 reflects recent advancements in the understanding of how elite athletes prepare for—and perform at—peak levels during competition. The latest release in this series focuses on a variety of topics, including chapters on Great British medalists: Psychosocial biographies of Super-Elite and Elite athletes from Olympic sports, a chapter on elite and super-elite Great British athletes: Some theoretical implications from Hardy et al.’s (2016) findings, and The psychosocial development of world class athletes: Additional considerations for understanding the whole person and salience of adversity. This series takes a multidisciplinary approach, focusing on aspects of psychology, neuroscience, skill learning, talent development and physiology.

  • The Rewiring Brain

    A Computational Approach to Structural Plasticity in the Adult Brain
    • 1st Edition
    • Arjen van Ooyen + 1 more
    • English
    The adult brain is not as hard-wired as traditionally thought. By modifying their small- or large-scale morphology, neurons can make new synaptic connections or break existing ones (structural plasticity). Structural changes accompany memory formation and learning, and are induced by neurogenesis, neurodegeneration and brain injury such as stroke. Exploring the role of structural plasticity in the brain can be greatly assisted by mathematical and computational models, as they enable us to bridge the gap between system-level dynamics and lower level cellular and molecular processes. However, most traditional neural network models have fixed neuronal morphologies and a static connectivity pattern, with plasticity merely arising from changes in the strength of existing synapses (synaptic plasticity). In The Rewiring Brain, the editors bring together for the first time contemporary modeling studies that investigate the implications of structural plasticity for brain function and pathology. Starting with an experimental background on structural plasticity in the adult brain, the book covers computational studies on homeostatic structural plasticity, the impact of structural plasticity on cognition and cortical connectivity, the interaction between synaptic and structural plasticity, neurogenesis-related structural plasticity, and structural plasticity in neurological disorders. Structural plasticity adds a whole new dimension to brain plasticity, and The Rewiring Brain shows how computational approaches may help to gain a better understanding of the full adaptive potential of the adult brain. The book is written for both computational and experimental neuroscientists.

  • Psychometrics and Psychological Assessment

    Principles and Applications
    • 1st Edition
    • Carina Coulacoglou + 1 more
    • English
    Psychometrics and Psychological Assessment: Principles and Applications reports on contemporary perspectives and models on psychological assessment and their corresponding measures. It highlights topics relevant to clinical and neuropsychological domains, including cognitive abilities, adaptive behavior, temperament, and psychopathology.More... the book examines a series of standard as well as novel methods and instruments, along with their psychometric properties, recent meta-analytic studies, and their cross-cultural applications.

  • Essentials of Noncoding RNA in Neuroscience

    Ontogenetics, Plasticity of the Vertebrate Brain
    • 1st Edition
    • Davide De Pietri Tonelli
    • English
    Essentials of Noncoding RNA in Neuroscience: Ontogenetics, Plasticity of the Vertebrate Brain focuses on the role of miRNAs in neurogenesis, gliogenesis, neuronal network formation, and the cell biology of forebrain development. The important role miRNAs play in neuronal maturation, neocortex function, and in some neurodevelopmental disorders is discussed, as are the computational challenges and methods used in the identification of miRNA targets. This book is a valuable reference for neuroscientists who wish to better understand the role of miRNAs in complex processes. It is of strong interest to those working to develop enabling technologies to detect and monitor miRNA expression and function, and to evaluate its roles in neural progenitor proliferation/differ... neuronal plasticity, and learning and memory.

  • Models of Seizures and Epilepsy

    • 2nd Edition
    • Asla Pitkänen + 3 more
    • English
    Models of Seizures and Epilepsy, Second Edition, is a valuable, practical reference for investigators who are searching for the most appropriate laboratory models to address key questions in the field. The book also provides an important background for physicians, fellows, and students, offering insight into the potential for advances in epilepsy research as well as R&D drug development. Contents include the current spectrum of models available to model different epilepsy syndromes, epilepsy in transgenic animals, comorbidities in models of epilepsy, and novel technologies to study seizures and epilepsies in animals.

  • Choroidal Disorders

    • 1st Edition
    • Jay Chhablani + 1 more
    • English
    Choroidal Disorders provides an overview on various chorioretinal disorders with a special emphasis on choroidal imaging. As our understanding of the choroid has significantly improved with the development of advanced optical coherence tomography (OCT) and its role in posterior segment diseases is gaining new significance, this book focuses on the related improvements, diagnostic capabilities, management and prognosis of various chorioretinal disorders. It covers conventional techniques, such as ultrasonography and indocyanine green angiography as well as the most advanced techniques, including enhanced depth imaging OCT, swept source OCT, and OCT angiography.

  • Fragile X Syndrome

    From Genetics to Targeted Treatment
    • 1st Edition
    • Rob Willemsen + 1 more
    • English
    Fragile X Syndrome: From Genetics to Targeted Treatment provides a structured overview of the molecular and clinical background of the disorder as well as treatment options. The book discusses the detailed molecular information on each of the pathways involved with sufficient details for all whose research touches this pathway. It provides a state-of-the-art update on all clinical aspects associated with this syndrome, including phenotype, diagnostics and epidemiology. It also includes an overview of the lessons learned from the preclinical research and pioneering trials on the fragile X syndrome for the investigators involved in clinical trials of neurodevelopmental disorders. This book is written for academic researchers, pharmaceutical investigators, and clinicians in the field who work on the disorder, and for researchers involved in clinical trials of the fragile X syndrome or related disorders. “This fascinating book, edited by Rob Willemsen and Frank Kooy, summarizes the current knowledge of the molecular aspects of fragile X syndrome (FXS), andthe potential for therapies resulting from this knowledge...Particul... interesting is a review “fragile X research from a parental perspective,” which summarizes the results of an international survey of the attitudes of families with FXS relatives towards research…This book is also an essential reference book for genetic counselors...The book provides counselors with the necessary biological background for proper explanations to the relatives of FXS patients. Many parents acquire a substantial knowledge of the conditions afflicting their children. The book will be helpful for both families and counselors to manage the expectations of families participating in clinical trials…In conclusion, this book is essential for everyone who is involved in the diagnosis and treatment of FXS patients.” - European Journal of Human Genetics (September 2018)

  • Functional Neural Transplantation IV

    Translation to Clinical Application, Part B
    • 1st Edition
    • Volume 231
    • English
    Functional Neural Transplantation IV: Translation to Clinical Application, Part B, Volume 231 provides the current status of cell transplantation in the nervous system, focusing on the conditions for achieving structural repair and functional recovery. New to this edition are chapters on Plasticity and Regeneration in the Injured Spinal Cord After Cell Transplantation Therapy, Transplantation of GABAergic Interneurons for Cell-Based Therapy, Rebuilding CNS Inhibitory Circuits to Control Chronic Neuropathic Pain and Itch, From Transplanting Schwann Cells in Experimental Rat Spinal Cord Injury to their Transplantation into Human Injured Spinal Cord in Clinical Trials, and the Recruitment of Endogenous CNS Stem Cells for Regeneration in Demyelinating Disease. As the fourth in a periodic series of updates at 5-7 year intervals, this volume highlights recent developments in cellular and molecular science, providing the fundamental principles of neuroplasticity and regeneration in the brain and spinal cord, while also addressing the power of pluripotent stem cells to generate new sources of precisely specified neurons for utilization in brain repair.

  • Parkinson's Disease

    • 1st Edition
    • Volume 132
    • English
    Parkinson's Disease, Volume 132 addresses new developments in the F33 study of this disease, highlighting how the lives of people with Parkinson’s have undergone dramatic changes in the last decade. New to this edition are chapters on the Hallmarks of clinical aspects PD throughout centuries, The motor syndrome of Parkinson disease, The non-motor features of Parkinson’s disease, The New Diagnostic Criteria for Parkinson's disease, Advances in the Clinical Differential diagnosis, Clinical assessments in PD : Scales and monitoring, Biomarkers of Parkinson’s disease: an Introduction, and the Genetics of Parkinson’s Disease: Genotype-Phenotype Correlations. The topics discussed in this comprehensive series provide a clearer understanding of the prodromal stage, genetics, strategies, routes of treatment, and development of non-dopaminergic therapies in Parkinson's Disease, both medical and surgical.

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