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Books in Molecular biology cellular biology and genetics

This collection offers insights into gene expression, cell signalling, and genetic regulation. Supporting researchers, clinicians, and students, it features advanced techniques, genetic engineering, and disease mechanisms, fostering innovations in personalized medicine, regenerative therapies, and molecular diagnostics.

  • Transketolases

    • 1st Edition
    • Volume 722
    • November 7, 2025
    • English
    Transketolase is an ubiquitous enzyme which has not yet finished revealing all its secrets. This Methods in Enzymology: Transketolases volume is devoted to the description of cutting-edge methods to its study in biochemistry. Several topics are addressed by world experts in their field.The first part of this volume deals with transketolase at the cellular level. The latest scientific progress on human transketolase TKL1 in relation to certain diseases and to its inhibition are discussed including the involvement of this enzyme in new metabolic pathways or as a diagnostic biomarker.The second part focuses on transketolase at the molecular level. The structural and mechanistic aspects linked to this enzyme are addressed using several approaches including molecular modelling and crystallography, for example. Finally, the experimental methodological approaches relating to the use of transketolase as a tool of choice in biocatalysis is presented.

  • Genome Analysis

    Principles and Methods
    • 1st Edition
    • November 7, 2025
    • Dev Bukhsh Singh + 1 more
    • English
    Genome Analysis: Principles and Methods provides recent and advanced information about genome analysis approaches and techniques to study and annotate the structure and function of the genome. It is a compendium of important topics such as NGS analysis, genome fragmentation and assembly, metagenomics, cloning and expression, physical marker analysis, transcriptome data analysis, sequence alignment and comparison, evolutionary analysis, SNP analysis, genome-based disease diagnosis and therapies, micro-RNAs, pharmacogenomics, genetic approaches to disease intervention, and challenges with opportunities in genome analysis and genomics, etc.The latest developments in the field are discussed, and key concepts are introduced to ensure readers understand advanced concepts and methodologies in the area. The book serves as a valuable guide to the present, emerging, and evolving research methodologies in the field.

  • Advances in Management of Pediatric Brain Tumors

    • 1st Edition
    • Volume 167
    • November 5, 2025
    • English
    Advances in Management of Pediatric Brain Tumors, Volume 167 encapsulates the latest developments in the field for various types of pediatric brain tumors. By examining these survival gaps, the volume offers insights into strategies for improving outcomes and bridging the gap in care on a global scale. Chapters in this new release include Pediatric-type diffuse low grade gliomak, Pediatric-type diffuse high grade glioma/Diffuse Midline glioma, Ependymoma, Choroid plexus tumors, Embryonal tumors/medulloblasto... Craniopharyngioma and other sellar-region tumors, and much more.Other sections cover Germ cell tumors, Immunotherapy for pediatric brain tumors, Emerging interventional treatments in the management of pediatric brain tumors, and Management of pediatric brain tumors in low-middle income countries.

  • γδ T Cells in Health and Disease Part B

    • 1st Edition
    • Volume 398
    • November 5, 2025
    • English
    γδ T Cells in Health and Disease, Part B provides a comprehensive and up-to-date overview of the diverse roles that γδ T cells play in human physiology and pathology. This volume builds on foundational knowledge to explore advanced topics and recent discoveries in γδ T cell biology, with a particular focus on their mechanisms of action, functional diversity, and implications for clinical practice. Chapters in this new release cover Development of gd T cells, Human T-cell receptor inborn errors of immunity shed light on the real-life role of γδ vs αβ T lymphocytes, and much more.Other sections explore Deciphering the Role of γδ T cells in Skin Inflammatory Diseases: Insights from Psoriasis, Atopic Dermatitis, and Alopecia Areata, Role of gd T cells in zoonosis infection, γδ T cells in Escherichia coli infection and Gamma-delta T cells in breast cancer: dual role in tumor immunity and emerging therapeutic approaches.

  • Investigative and Predictive DNA Testing

    • 1st Edition
    • November 5, 2025
    • Hirak Ranjan Dash
    • English
    Investigative and Predictive DNA Testing delves into the cutting-edge of DNA analysis, presenting a comprehensive guide that unlocks the potential of DNA in solving complex cases. This book stands as a vital resource for students, practitioners, and researchers in fields such as biology, zoology, medicine, anthropology, microbiology, and genetics. Designed for those with a basic understanding of biological sciences, it is particularly beneficial for graduate, post-graduate, and research level students. The book explores the evolution of DNA analysis, focusing on predictive methods and investigative leads such as ancestry, lineage, and phenotype.Each chapter, contributed by internationally renowned experts, highlights the transformative role of artificial intelligence and machine learning in enhancing the accuracy and utility of DNA analysis. The book is comprised of various sections, starting with fundamental concepts of investigative and predictive DNA analysis, followed by technological advancements in the field, and concluding with the challenges and future concerns of DNA analysis. It serves as an indispensable tool for anyone looking to expand their knowledge and skills in DNA analysis, making it a must-read for the scientific community.

  • γδ T Cells in Health and Disease Part A

    • 1st Edition
    • Volume 397
    • October 30, 2025
    • English
    γδ T Cells in Health and Disease, Part A, provides a comprehensive overview of the biology, function, and clinical significance of γδ T cells, a unique subset of T lymphocytes with distinct roles in immune responses. This volume brings together leading experts to explore the fundamental aspects of γδ T cell development, activation, and regulation, as well as their involvement in maintaining health and contributing to disease.

  • Enzyme Reprogramming

    • 1st Edition
    • Volume 721
    • October 30, 2025
    • English
    Enzyme Reprogramming, Volume 719 in the Methods in Enzymology series, highlights new advances in the field, with this new volume presenting interesting chapters on topics such as Practical Considerations for Reaction Development with Vanadium-Dependent Haloperoxidases, Characterization and Engineering of thermostable PLP-dependent alpha-oxoamine synthases (AOSs); versatile C-C bond forming biocatalysts, Thiamine diphosphate Enzymes for Photobiocatalytic Enantioselective C(sp3)–H Acylation, Engineering a PLP-dependent Mannichase, Transferase engineering for SAM analog synthesis using combinatorial library design and high-throughput screening, Biaryl Coupling reactions catalyzed by Cytochrome P450s, and much more.Other chapters cover Engineering of a-ketoglutarate-depe... amino acid hydroxylases, Repurposing thiamine-dependent enzymes for radical biocatalysis, Directed evolution of nonheme Fe Enzymes for azidation, Directed evolution of P450 dearomatases for catalytic asymmetric radical dearomatization, Genetically encoded artificial photoenzymes for enantioselective [2+2] photocycloadditions, Unmasking the Reverse Activity of Old Yellow Enzymes for Selective Carbonyl Desaturation, and more.

  • Techniques and Protocols in Molecular Biology

    • 1st Edition
    • October 28, 2025
    • Buddhi Prakash Jain
    • English
    Techniques and Protocols in Molecular Biology delivers detailed practical guidance for a variety of molecular techniques and procedures. Each chapter focuses on a different technique including isolation techniques for DNA and RNA, gene cloning, PCR, ELISA, and cell culture. These protocols include a detailed description of the technique along with the main principles, required equipment, and comprehensive steps to assist researchers with replicating the protocol and performing the techniques themselves.This foundational reference is essential for students and researchers looking to enhance their understanding of key molecular techniques and reproduce them successfully in their own laboratory work.

  • Taxonomic Impediments of the Benthic Infauna; Potential Solutions and Consequences

    • 1st Edition
    • Volume 101
    • October 24, 2025
    • English
    Taxonomic Impediments of the Benthic Infauna; Potential Solutions and Consequences, Volume 101 in the Advances in Marine Biology series, explores the critical role of taxonomy in understanding and conserving marine biodiversity. This volume presents a comprehensive review of the taxonomic challenges facing marine invertebrates and potential solutions through molecular and genetic advancements. Topics include advancing marine invertebrate biodiversity research in South Africa, the current status of DNA barcoding for marine invertebrates, and identification challenges in ASEAN countries and their management implications.Additio... chapters examine benthic communities around Australia and their role in marine park management, taxonomic and conservation challenges in the southwestern Atlantic, and strategies for biodiversity inventories in poorly studied marine areas. The volume also highlights specific case studies on Mauritanian sponges, benthic copepods using molecular methods, and taxonomic barriers to echinoderm biogeography and conservation.

  • From DNA to Traditional Chinese Medicine

    • 1st Edition
    • October 23, 2025
    • Jesse Li-Ling
    • English
    From DNA to Traditional Chinese Medicine presents how genetic disorders can be explained using concepts of Traditional Chinese Medicine. This book explores the striking correlation between the characteristics of congenital syndromes and fundamental concepts of Traditional Chinese Medicine, such as Jing-Mai (Meridians or Channels) and Zang-Fu (the Yin and Yang internal organs). This correlation appears to be systematic and comprehensive, suggesting that these Chinese concepts have correctly summarized the connections between particular parts of the human body during embryonic development. Should this discovery be correct, it will have an immense impact on the understanding of genomic medicine as well as Chinese medicine. The uncovering of the mechanism of Chinese medicine, may also lead to development of new treatments for various human diseases. This book covers topics including genetic syndromes and fundamental concepts of Traditional Chinese Medicine. Starting with DiGeorge/Velocardiof... syndrome, this book will first introduce the basics of Medical Genetics and congenital syndromes, and then the fundamental concepts of Traditional Chinese Medicine including Jing-Mai and Zang-Fu. It will provide a completely new perspective on genetic syndromes with insights into how they relate to Traditional Chinese Medicine. This book is a valuable resource for graduates, medical undergraduates and researchers as well as professionals from both academia and industry.

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