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Books in Molecular biology cellular biology and genetics

This collection offers insights into gene expression, cell signalling, and genetic regulation. Supporting researchers, clinicians, and students, it features advanced techniques, genetic engineering, and disease mechanisms, fostering innovations in personalized medicine, regenerative therapies, and molecular diagnostics.

  • Biology of Fatty Acids

    Biochemical, Nutritional and Pharmacological Functions
    • 1st Edition
    • E. P. Meran Keshawa + 1 more
    • English
    Biology of Fatty Acids: Biochemical, Nutritional, and Pharmacological Functions offers an in-depth exploration of the vital roles fatty acids play in human health. From their influence on metabolism and immune functions to their potential in disease prevention and treatment, this book covers a wide range of topics. With contributions from leading experts, it examines the latest research on fatty acids in nutrition, emerging plant-based sources, and their pharmacological potential in treating conditions like neurodegenerative diseases and cancer. A must-read for scientists, healthcare professionals, and anyone interested in the transformative impact of fatty acids on human health.

  • Bacterial Efflux Systems

    • 1st Edition
    • Volume 724
    • English
    Bacterial Efflux Systems, Volume 722 covers experimental and computational approaches to study the function, structure, and mechanism of bacterial efflux pump systems. The methods covered include preparation of samples for structural and functional analyses and in vivo activity analysis. Specific chapters in this release cover Efflux pump functional assays, NMR and functional analysis efflux pumps, Methods for saturation mutagenesis and functional characterization, Cooperation and functional interplay between pumps, Mapping interactions, HDX-MS, and much more.Other sections cover Recombinant Expression and purification, Reconstitution of a RND efflux pump in different artificial membranes for a structural biology approach, Reconstitution of rnd and mfs efflux pumps for structural biology, CusCBA system, Expression and purification of efflux pumps of Gram positives, Expression and purification of efflux pumps of archaea, ABC transporters: BmrA preparation for NMR and PatA/PatB in peptidisc, In situ structural analysis of efflux assemblies by cryoET, Molecular dynamics simulations, and so much more.

  • Cyclic Peptides

    • 1st Edition
    • Volume 723
    • English
    Cyclic Peptides, Volume 721 covers peptide structures and their enhancement, stability, specificity, and overall functionality. As a growing suite of computational and experimental tools support the discovery and optimization of these molecules, ranging from well-established modeling platforms to emerging deep-learning algorithms that expand design possibilities, this book aims to provide a comprehensive overview of cyclic peptide research, covering fundamental principles, production strategies, and the latest technological advances in both synthetic and computational realms.Cyclic peptides are a powerful approach to constraining peptide structures, enhancing their stability, specificity, and overall functionality. They can be generated through diverse techniques—including chemical synthesis, mRNA display, and DNA display—that enable the creation of tailored peptide libraries.

  • Advances in Cancer Research

    • 1st Edition
    • Volume 168
    • English
    Advances in Cancer Research, Volume 168 in this ongoing series, highlights new advances in the field, with this new volume presenting interesting chapters on topics such as Plasticity in cell adhesion during cancer progression, AEG-1 on Cancer Drug Resistance: From Molecular Insights to Therapeutic Challenges, Multimodal AI to differentiate tumor progression from treatment effect in glioblastoma, The Role of Epigenetic Modifications in Mediating Cancer Health Disparities, In search of a targetable immune profile for acute myeloid leukemia, Notch signaling in tumorigenesis and maintenance of cancer stem cells, and much more.

  • The Future of Human Evolution

    • 1st Edition
    • Rene J. Herrera + 1 more
    • English
    The Future of Human Evolution provides a discussion of how cultural, biological and microevolutionary (drift, selection, and mutation) pressures might affect our future as a species. The book is split into twelve chapters, beginning with evolutionary forecasting, and gene and culture coevolution. It then discusses life expectancy and population growth, followed by chapters on mutation rates, climate change and diet. This book also explores artificial selection and ‘designer babies’, trans-humanism and artificial intelligence (machine-human symbiosis), inequality and the colonization of space. The Future of Human Evolution serves as a valuable resource for both researchers and students studying human evolution and human population genetics, as well as non-academics with an interest in human evolution.

  • Extracellular Vesicles: Advances and Perspectives in Treatments, Therapies, and Vaccination

    • 1st Edition
    • Volume 96
    • English
    Extracellular Vesicles: Advances and Perspectives in Treatments, Therapies, and Vaccination, Volume 96 explores the field of extracellular vesicles (EVs) and their potential applications in treatments, therapies, and vaccination. Covering a broad range of topics from EV-based biomarker detection to vaccine development and theranostic applications, this new release in the series includes chapters on Extracellular Vesicles: Advances in Treatments, Therapies, and Vaccination, Extracellular Vesicles: Advances in Therapies and Vaccination in virus, Products of excretion-secretion and extracellular vesicles derived from zoonotic helminths: a two-face response, and more.Additional sections cover Extracellular Vesicles in Fungal Pathogenesis: Mechanisms and Implications, Extracellular vesicle-based vaccines: a promising approach for parasitic diseases, Extracellular Vesicles as Vaccines Against Infectious Diseases, EVs and images, Bacterial Outer Membrane Vesicles: Potential and Applications in Next-Generation Vaccines, Theranostic application of extracellular vesicles in breast cancer, and much more.

  • Advances in Marine Biology

    • 1st Edition
    • Volume 102
    • English
    Advances in Marine Biology, Volume 102 in the Advances in Marine Biology series, the latest release in this long-standing serial, presents cutting-edge developments in marine biology with a focus on diverse themes influencing ocean ecosystems. This volume features chapters on highly informative topics such as The Inclusion of habitat quality into fisheries models, The urgent need to better define, quantify and identify the drivers of "water quality" on tropical coral reefs (opinion article), Indigenous knowledge and marine systems, and Sensory perception in marine larvae.

  • Biochemical and Molecular Mechanisms of Secondary Metabolites in Metabolic Diseases

    • 1st Edition
    • Kanwal Rehman + 1 more
    • English
    Biochemical and Molecular Mechanisms of Secondary Metabolites in Metabolic Diseases explores the therapeutic potential and pharmacological roles of secondary metabolites (SMs) in managing metabolic disorders. This comprehensive volume provides a detailed examination of the biochemical pathways, molecular mechanisms, and pharmacodynamics of SMs, offering insights into their potential as future drug candidates for metabolic diseases. The book begins by explaining the differences between secondary and primary metabolites, providing clear classification and organization of SMs. It highlights recent research on SMs, including receptor interactions and molecular signal transduction pathways, to showcase their potential as interventions against metabolic disorders.The role and mechanistic details of SMs at the molecular level are illustrated, emphasizing their pharmacological participation in treating conditions such as obesity, diabetes, cardiovascular diseases, and inflammation. This book is an essential resource for students and professionals in pharmacy, medical subjects, nursing, herbal medicine, and traditional medicine programs, aligning with curricula in medical ethnobotany, ethnopharmacology, pharmacognosy, phytochemistry, and related fields. It also serves as a valuable reference for researchers in pharmacology, biochemistry, and medicinal chemistry, as well as clinicians interested in natural product-based therapeutics for managing metabolic conditions.

  • Transketolases

    • 1st Edition
    • Volume 722
    • English
    Transketolase is an ubiquitous enzyme which has not yet finished revealing all its secrets. This Methods in Enzymology: Transketolases volume is devoted to the description of cutting-edge methods to its study in biochemistry. Several topics are addressed by world experts in their field.The first part of this volume deals with transketolase at the cellular level. The latest scientific progress on human transketolase TKL1 in relation to certain diseases and to its inhibition are discussed including the involvement of this enzyme in new metabolic pathways or as a diagnostic biomarker.The second part focuses on transketolase at the molecular level. The structural and mechanistic aspects linked to this enzyme are addressed using several approaches including molecular modelling and crystallography, for example. Finally, the experimental methodological approaches relating to the use of transketolase as a tool of choice in biocatalysis is presented.

  • Genome Analysis

    Principles and Methods
    • 1st Edition
    • Dev Bukhsh Singh + 1 more
    • English
    Genome Analysis: Principles and Methods provides recent and advanced information about genome analysis approaches and techniques to study and annotate the structure and function of the genome. It is a compendium of important topics such as NGS analysis, genome fragmentation and assembly, metagenomics, cloning and expression, physical marker analysis, transcriptome data analysis, sequence alignment and comparison, evolutionary analysis, SNP analysis, genome-based disease diagnosis and therapies, micro-RNAs, pharmacogenomics, genetic approaches to disease intervention, and challenges with opportunities in genome analysis and genomics, etc.The latest developments in the field are discussed, and key concepts are introduced to ensure readers understand advanced concepts and methodologies in the area. The book serves as a valuable guide to the present, emerging, and evolving research methodologies in the field.

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