Skip to main content
Elsevier
View Cart

Books in Molecular biology cellular biology and genetics

BooksJournals

    • Advances in Noncoding RNA Diagnostics and Therapeutics in Immunity and Cancer

      • 1st Edition
      • Afsar Naqvi + 1 more
      • English
      Advances in Noncoding RNA Diagnostics and Therapeutics in Immunity and Cancer offers an in-depth exploration of the pivotal role noncoding RNAs play in immune-mediated diseases and various cancers. This essential volume provides readers with a comprehensive understanding of how noncoding RNAs influence immune responses, drive inflammation, and contribute to cancer progression. By presenting the latest research on noncoding RNA mechanisms, interactions, and functions, the book positions these molecules as promising biomarkers and therapeutic targets. Researchers and clinicians will find valuable insights into the diagnostic and therapeutic potential of noncoding RNAs within this rapidly evolving field.Beyond foundational concepts, the book discusses subjects such as the role of virus-encoded microRNAs in immune evasion, therapeutic applications in hepatocellular carcinoma, and the impact of microRNAs on periodontal inflammation. It further examines how miRNAs and lncRNAs regulate the tumor microenvironment, the functions of tumor-derived exosomes, and the panorama of noncoding RNA in prostate cancer.

    • Cryo-EM Methods and Management

      • 1st Edition
      • Edward T. Eng + 2 more
      • English
      Cryo-EM Methods and Management provides a detailed introduction to the latest advances of cryo-EM, from technical innovations to the logistical challenges of maintaining a modern cryo-EM facility. The book consists of four parts, beginning with an overview of cryo-EM. It then moves on to discuss Cryo-EM workflows, with chapters focusing on sample handling and preparation, data collection and hardware, and data procession and visualization. The third part centers on aspects of cryo-EM infrastructure and community building, considering facility set-up and management, monitoring facility performance, instrumentation monitoring , data sharing and standards, and training and development standards. The book then closes with a section looking towards future prospects for cryo-EM. This is an ideal reference for cryo-EM facility and lab managers, providing guidance to the often-overlooked aspect of facility building and management. Additionally researchers working with cryo-EM across molecular biology, structural biology, cell biology and biochemistry will benefit from this book.

    • Computational Approaches to Natural Products Discovery

      • 1st Edition
      • Volume 730
      • English
      Computational Approaches to Natural Products Discovery, Volume 720 provides descriptions of the latest techniques in computational methods for the study of natural products. Techniques covered are related to genome mining, natural product biosynthesis, natural product evolution, and natural product structure. Chapters in this new release cover Prediction of natural product bioactivity from BGC sequence to guide genome mining efforts, Genome mining for resistance genes to identify bioactive natural products with ARTS, Predicting lasso peptide structure with LassoPred, Predicting lanthipeptide structure with Rosetta, Using lsaBGC to investigate BGC Evolution, and an Analysis of BGC evolution with CORASON.

    • RNases in Health and Diseases

      From Housekeeping Enzymes to Moonlight Proteins
      • 1st Edition
      • Ester Boix
      • English
      RNases in Health and Diseases: From Housekeeping Enzymes to Moonlight Proteins presents a comprehensive exploration of the structural and functional properties of RNases, revealing their importance well beyond basic cellular maintenance. The book introduces readers to the evolving landscape of RNase research, including their multifaceted roles and newly discovered capabilities. Particularly notable are their contributions to the generation of non-coding signaling RNAs and their emerging potential as tools for diagnostics and therapy. The content is organized into three distinct sections, beginning with RNase structure and continuing with research methods and advanced tools for studying these enzymes.In addition to foundational knowledge, the final section investigates the connections between RNases and various diseases, illustrating their clinical relevance. This resource offers both researchers and students a broad perspective, making it valuable for anyone seeking a solid background in RNase biology. Readers will gain insights into recent breakthroughs, research techniques, and the therapeutic possibilities that position RNases at the forefront of biomedical innovation.

    • Nerve Growth Factor

      From Neuron Development to Neurology
      • 1st Edition
      • Antonino Cattaneo + 1 more
      • English
      Nerve growth factor: From Neuron Development to Neurology, the latest release in the Molecular Mediators in Health and Disease series, offers a complete guide to nerve growth factor (NGF) across health and disease. Sections cover key properties, the latest advances, and biomedical applications of this neuropeptide. The book begins with an introduction and historical overview of the discovery of NGF before exploring its molecular characteristics. It then covers NGF in organ function, with chapters discussing the brain, immune system, blood vessels, heart, reproductive organs, teeth, and lungs. NGF pharmacology is then considered, with a focus on NGF as a therapeutic agent.The final section of the book covers NGF across diseases, including Alzheimer’s disease, cancer, diseases of the eye, chronic pain, and visceral disfunctions. Throughout the book, NGF is considered in the context of both mammalian and non-mammalian biology, making it an ideal reference for researchers working across the fields of cell biology, molecular biology, pharmacology, and other biomedical areas.

    • Chromatin Signaling and Diseases

      • 2nd Edition
      • Olivier Binda + 2 more
      • English
      Chromatin Signaling and Diseases, Second Edition, a volume in the Translational Epigenetics series, covers the molecular mechanisms that regulate gene expression, which governs embryonic development, growth, and human pathologies associated with aging, such as cancer. Although human genome sequencing continues to improve, molecular mechanisms regulating gene expression remain largely misunderstood. The impact of gene expression defects associated with malfunctioning chromatin signaling are considered in this update. In addition, this new edition has addresses developments in the field, from phase separation of membrane-less organelles and local segregation of factors to chromatinization of naked foreign DNA and cancer evolution as regulated by chromatin signaling.Chromatin signaling proposes that small protein domains recognize chemical modifications on the genome scaffolding histone proteins, facilitating the nucleation of enzymatic complexes at specific loci that then open up or shut down the access to genetic information, thereby regulating gene expression. The addition and removal of chemical modifications on histones, as well as the proteins that specifically recognize these are also considered.

    • Innovative Nanotechnology: Transforming Skin Cancer Diagnosis and Treatment

      • 1st Edition
      • Volume 169
      • English
      Innovative Nanotechnology: Transforming Skin Cancer Diagnosis and Treatment, Volume 169 in the Advances in Cancer Research series, highlights new advances in the field, with this new volume presenting interesting chapters written by an international board of authors. Chapters in this new release include an Introduction to Nanotechnology in Dermatology, Basics of Skin Cancer: Types, Diagnosis, and Current Challenges, Current Challenges in Skin Cancer Diagnosis and Treatment, Nanocarriers for Drug Delivery in Skin Cancer, Nanotechnology in Skin Cancer Diagnosis, Therapeutic Nanoparticles and Targeted Therapy, and much more.Additional chapters cover Nanotechnology in Photodynamic and Photothermal Therapy for Skin Cancer, Challenges in Translating Nanotechnology from Research to Clinical Practice, Nanotechnology and Immunotherapy Synergies in Skin Cancer, Patient-Centric Approaches and Personalized Nanomedicine in Skin Cancer, The Role of Theranostics and Nanotheranostics in Skin Cancer Management, Preclinical and Clinical Trials in Nanotech Skin Cancer Treatment, Safety, Ethical, and Regulatory Considerations in Nanotechnology for Skin Cancer, and many more interesting chapters on topics of current interest.

    • Profiles of Drug Substances, Excipients, and Related Methodology

      • 1st Edition
      • Volume 51
      • English
      Profiles of Drug Substances, Excipients, and Related Methodology, Volume 51 provides comprehensive profiles of four pharmaceutical compounds: Vortioxetine, Rosuvastatin Calcium, Perindopril, and Ferulic Acid. In addition, it includes a review article concerning Drugs and Polymer Based Local Delivery Systems in the Treatment of Periodontal Diseases. Chapters in this new release include Vortioxetine: A Comprehensive Profile, Rosuvastatin Calcium: A Comprehensive Profile, Ferulic Acid: A Comprehensive Profile, Perindopril: A Comprehensive Profile, Drugs and Polymer Based Local Delivery Systems in the Treatment of Periodontal Diseases, Kinetic Exclusion Assay Technology: Theory, Experimental Aspects, and Applications in Concentration Measurements Across Diverse Fields, and more.No other book series provides this essential information as promptly and pertinently. Sections provide review articles and database compilations categorized into five primary domains: Physical Profiles of Drug Substances and Excipients; Analytical Profiles of Drug Substances and Excipients; ADME Profiles of Drug Substances and Excipients; Methodology Pertaining to the Characterization of Drug Substances and Excipients; and Methods of Chemical Synthesis.

    • Molecular Mechanisms of Spermatogenesis

      • 1st Edition
      • Volume 168
      • English
      Molecular Mechanisms of Spermatogenesis, Volume 168 provides a comprehensive overview of the molecular mechanisms that govern spermatogenesis, the complex process through which sperm cells are produced in the male testes. Sections in this new release include: From undifferentiated gonads to ovaries and testes, Molecular regulation of germ-somatic cell interactions: insights from spatial transcriptomics, All about the mammalian germline cyst, Stem cell competition, Genetic and epigenetic regulation of cell fate determination of human spermatogonial stem cells, A Sertoli Valve niche at the Terminal End of Seminiferous Tubules for Mammalian Spermatogenic Stem Cells, The formation and function of the synaptonemal complex, and more.Additional sections cover Meiotic crossover control: interplay between the recombination process and chromosome organization, Drosophila spermiogenesis, New Insights on the Biogenesis and Functional Importance of the Sperm Cytoplasmic Droplet, Asymmetric male meiosis in genetics and evolution, Current understanding of adult stem cells in Leydig cell biology, Unraveling the complexity of spermatogenesis from single-cell perspective, and much more.

    • Vector Borne Diseases

      • 1st Edition
      • Volume 58
      • English
      Vector Borne Diseases, Volume 58 in the Methods in Microbiology series, highlights new advances in the field, with this new volume presenting interesting written by an international board of authors. Chapters in this new release cover Methods for Isolation and Characterization of Arthropod Hemocytes, Tick-to-Host Transmission of B. burgdorferi: In Vitro and In Vivo Methodologies, Decoding the Zika Virus outbreak and Infection Dynamics, Visual and molecular methods for studying pathogen persistence in flea vectors, Lipidomic Analysis of Virus-infected Cells, and Implementation of the Neutropenic Thigh Infection Murine Model with Francsiella tularensis for Development of New Antibacterials.

Related subjects

Applications of molecular genetics

Bioinformatics and computational biology

Carcinogenesis

Cellular biology

Comparative genetics

Cytogenetics

Developmental biology

Developmental genetics

Dna repair

Gene structure expression and regulation

General microscopy

Genetics

Genome research

Histochemistry cytochemistry

Human genetics

Molecular and genetic toxicology

Molecular biology

Molecular epidemiology

Molecular evolution

Molecular genetics

Mutagenesis

Population genetics

Protein structure and synthesis