Nerve Growth Factor
From Neuron Development to Neurology
- 1st Edition - May 4, 2026
- Editors: Antonino Cattaneo, Simona Capsoni
- Language: English
- Paperback ISBN:9 7 8 - 0 - 4 4 3 - 3 3 0 8 8 - 9
- eBook ISBN:9 7 8 - 0 - 4 4 3 - 3 3 0 8 9 - 6
Nerve growth factor: From neuron development to neurology offers a complete guide to nerve growth factor (NGF) across health and disease. It provides a well-rounded discus… Read more
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Nerve growth factor: From neuron development to neurology offers a complete guide to nerve growth factor (NGF) across health and disease. It provides a well-rounded discussion of NGF and the key properties, latest advances, and biomedical applications of this neuropeptide. The book begins with an introduction and historical overview of the discovery of NGF before exploring its molecular characteristics. It then covers NGF in organ function, with chapters ranging across the brain, immune system, blood vessels, heart, reproductive organs, teeth and lungs. NGF pharmacology is then considered in detail, with a focus on NGF as a therapeutic agent. The final section of the book covers NGF across disease, which includes Alzheimer’s disease, cancer, diseases of the eye, chronic pain and visceral disfunctions. Throughout the book, NGF is considered in the context of both mammalian and non-mammalian biology. Nerve growth factor: From neuron development to neurology is the latest volume in the Elsevier book series Molecular Mediators in Health and Disease, and is an ideal reference for researchers working across the fields of cell biology, molecular biology, pharmacology and other biomedical areas.
- Explores the pathways of NGF, its receptors and physiological functions
- Covers NGF in disease, including neurodegenerative disease and cancer
- Considers the therapeutic potential of NGF
Researchers at PhD level and above across biological and biomedical sciences including cell biology, molecular biology, pharmacology, and neuroscience
Part I - Introduction to Nerve Growth
1. History of Nerve Growth
2. Nerve Growth Factor in Normal Biology
Part II – Molecular biology of Nerve Growth
3. Production and structure of Nerve Growth
4. Measurement of Nerve Growth Factor and its precursor
5. Nerve Growth Factor receptors
Part III – Nerve Growth Factor in organ function
6. NGF in sensory and sympathetic neurons
7. NGF in Brain
8. NGF and the immune system
9. NGF in blood vessels and heart
10. NGF in reproductive organs
11. NGF in teeth
12. Nerve Growth Factor and the Lung.
Part IV – Nerve Growth Factor pharmacology
13. TrkA mimetics
14. P75NTR receptor blockers
15. Antibodies neutralizing NGF or TrkA
16. Nerve Growth Factor protein as a therapeutic agent
Part V – NGF in non-mammalian biology
17. NGF in non-mammalian organisms
Part VI - Nerve Growth Factor in Disease
18. Nerve Growth Factor and Alzheimer’s disease
19. Nerve Growth Factor and diseases of the eye
20. Nerve Growth factor and cancer
21. Nerve Growth Factor and chronic pain
22. Nerve Growth Factor and visceral disfunctions
1. History of Nerve Growth
2. Nerve Growth Factor in Normal Biology
Part II – Molecular biology of Nerve Growth
3. Production and structure of Nerve Growth
4. Measurement of Nerve Growth Factor and its precursor
5. Nerve Growth Factor receptors
Part III – Nerve Growth Factor in organ function
6. NGF in sensory and sympathetic neurons
7. NGF in Brain
8. NGF and the immune system
9. NGF in blood vessels and heart
10. NGF in reproductive organs
11. NGF in teeth
12. Nerve Growth Factor and the Lung.
Part IV – Nerve Growth Factor pharmacology
13. TrkA mimetics
14. P75NTR receptor blockers
15. Antibodies neutralizing NGF or TrkA
16. Nerve Growth Factor protein as a therapeutic agent
Part V – NGF in non-mammalian biology
17. NGF in non-mammalian organisms
Part VI - Nerve Growth Factor in Disease
18. Nerve Growth Factor and Alzheimer’s disease
19. Nerve Growth Factor and diseases of the eye
20. Nerve Growth factor and cancer
21. Nerve Growth Factor and chronic pain
22. Nerve Growth Factor and visceral disfunctions
- Edition: 1
- Published: May 4, 2026
- Language: English
AC
Antonino Cattaneo
Antonino Cattaneo is currently Professor of Neurobiology at the Scuola Normale Superiore (Pisa), Italy, where he is the Director of the Biology Lab Bio@SNS.
He is the author of numerous publications in peer-reviewed international journals and is recipient of several awards including Domenico Marotta Prize, Italian Academy of Sciences XL, the W. Jansenius Medal, Slovak Academy of Sciences and the “G. Tartufari” International Prize for Biology, Accademia Nazionale dei Lincei.
He is a member of EMBO (European Molecular Biology Organization) and the Italian Academy of Sciences XL.He is former member of the Council of Scientists of Human Frontier Science Program Organization (HFSPO), for which he has also served for four years as the Chairman of the Grants Review Committee. He has been Visiting Fellow of Trinity College in Cambridge (UK). He is a Team Leader of the European Neuroscience Institute Young Investigator Network.
Affiliations and expertise
Bio@SNS Laboratory, Scuola Normale Superiore, Pisa, ItalySC
Simona Capsoni
Simona Capsoni has served as Associate Professor of Physiology at University of Ferrara and Scuola Normale Superiore since 2016. Prior to this, in 2010 she joined the Bio@SNS Laboratory of Biology at Scuola Normale Superiore in Pisa (Italy) as contract junior professor where she discovered that NGF and hNGFp can affect the pathophysiology of glial cells, in particular microglia. At the same time, she started the line of research on NGF signalling system in painlessness diseases. She has published numerous papers and her primary research area focuses on the therapeutic application of hNGFp.
Affiliations and expertise
Department of Neuroscience and Rehabilitation University of Ferrara, Ferrara, Italy