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Elsevier

Books in Life sciences

  • The Covid-19 Response in New York City

    Crisis Management in the Epicenter of the Epicenter
    • 1st Edition
    • Syra S. Madad + 2 more
    • English
    The COVID-19 Response in New York City: Crisis Management in the Largest Public Health System provides an historical accounting of the response to the COVID-19 pandemic through the eyes of the largest public health system in the United States. The book offers a roadmap to guide healthcare systems and their providers in the event of future pandemics. Readers will learn about surge staffing and level loading, as well as tips from the ED and ICUs on how to respond to an unprecedented influx of inpatients. Written by healthcare providers who were at the epicenter of the pandemic in New York City, this book provides a sound accounting of the response to the pandemic in one of the world's largest cities.

  • Neurological and Neurosurgical Emergencies

    • 1st Edition
    • Indu Kapoor + 2 more
    • English
    Neurological and Neurosurgical Emergencies addresses emergencies in all fields of neuroscience, including disciplines like Neurology, Neurosurgery, Neuroanaesthesia, and Neuroradiology. This volume covers neurosurgical emergencies, like hydrocephalus, brain edema, intracranial bleed, intracranial hematoma, infection, and trauma, alongside neurovascular emergencies like acute ischemic stroke, non-traumatic, aneurysmal subarachnoid hemorrhage, carotid cavernous fistula, and arteriovenous malformation.In addition, the book discusses common emergencies in neurology, including status epilepticus, refractory epilepsy, super-refractory epilepsy, and neuromuscular disorders. Beginning with neurological examination of patients through to anesthetic management of various emergencies, this book features clear images that accompany each emergency with learner-friendly features such as flow-charts, figures, text boxes, and algorithms. This book provides insights into all possible aspects of emergency management and the anesthetic management of such patients.

  • Regenerative Medicine in the Genitourinary System

    • 1st Edition
    • Farshid Sefat + 1 more
    • English
    Regenerative Medicine in the Genitourinary System gives the reader a comprehensive overview of tissue engineering used to treat genitourinary disorders and infertility, also providing a great learning platform for researchers in different fields such as cell biology, pharmaceutics, clinicians, chemists, material scientists, and more. The book covers the latest innovations on the subject, but also acts as a resource for tissue engineering applications and regenerative medicine. Over the last several decades, tissue engineering has continued to make considerable advancements in therapeutic and clinical strategies that address male/female urological or genitourinary diseases.Although several articles have been published on this topic, there are very few book chapters and no single book currently available dedicated to this topic.

  • Biochar-assisted Remediation of Contaminated Soils Under Changing Climate

    • 1st Edition
    • Shah Fahad + 4 more
    • English
    Biochar-assisted Remediation of Contaminated Soils Under Changing Climate summarizes recent progress in understanding (a) metal-biochar interactions in soils, (b) potential risks associated with biochar amendment, and (c) the application of biochar for the remediation of HM polluted soils. In addition, research gaps and future directions in understanding biochar-metal interactions in soils is also explored. As soil contamination with heavy metals like Cr, Co, Cu, Ni, Mn, Cd, Pb, and Zn is becoming a big problem across the globe, especially in developed countries, this book elucidates on risks and future directions.Globally, it has become a serious threat to human health and ecosystem integrity. applying amendments like phosphate compounds, liming materials, clay minerals, coal fly ash, organic composts, metal oxides, and biochar to heavy metals contaminated soil is considered one of the most promising in-situ remediation techniques. Biochar has become one of the most attractive research hotspots as a result of its special properties, along with its important role in climate change, global biogeochemical cycle, and environmental system.

  • Fluorine Metabolism, Transport and Enzymatic Chemistry

    • 1st Edition
    • Volume 696
    • English
    Fluorine Metabolism, Transport and Enzymatic Chemistry, Volume 696 in the Methods in Enzymology series, highlights new advances in the field, with this new volume presenting interesting topics on Fluorine Metabolism, Transport, and Enzymatic Chemistry. Chapters in this new release include Determination of fluoride sensitivity and resistance in oral biofilm models, NMR methods to detect fluoride binding and transport by membrane proteins, Biotransformation of fluorinated drugs and xenobiotics by the model fungus Cunninghamella elegans, Measurement of fluoride efflux from lipid vesicles and cells, Defluorination of PFAS by Acidimicrobium sp. A6 and Potential Applications for Remediation, and more.Additional chapters cover Computational approaches to investigate F- binding, selectivity and transport in F- exporters, Defluorination as a key trait to gauge the biodegradability of fluorinated pollutants: challenges and opportunities, Patch-Clamp Electrophysiology of Fluoride Channels in Saccharomyces cerevisiae, and Synthesis of fluorophenylalanine-... proteins in HEK cells.

  • Advances in Applied Microbiology

    • 1st Edition
    • Volume 126
    • English
    Advances in Applied Microbiology, Volume 126 continues the comprehensive reach of this widely read and authoritative review source in microbiology where users will find invaluable references and information on a variety of areas relating to the topics of microbiology.

  • Overview of Inflammatory Breast Cancer: Updates

    • 1st Edition
    • Volume 384
    • English
    International Review of Cell and Molecular Biology, Volume 381 highlights new advances in the field, with this new volume presenting interesting topic on Overview of Inflammatory Breast Cancer: Updates.

  • Cellular, Molecular, and Environmental Contribution in Cardiac Remodeling

    From Lab Bench Work to its Clinical Perspective
    • 1st Edition
    • Asim K. Duttaroy + 1 more
    • English
    Cellular, Molecular and Environmental Contribution in Cardiac Remodeling consolidates the most recent research advances on cellular, molecular, biochemical, and heterogeneous factors contributing to the physiological and pathological cardiac remodeling, elucidating their mechanisms of action and the clinical outcomes of cardiac remodeling. The book extensively covers the factors determining cardiac remodeling, including cardiomyocyte regeneration, cardiac stem cells and their therapeutic potential, cardiac resident pericytes, the role of natural bioactive compounds in cardiac remodeling, chronic cardiac adaptations to exercise, and more.It provides basic science researchers and clinical investigators in cardiology with a current and comprehensive resource on molecular mechanisms and contributing factors to cardiac remodeling, along with its effects and impacts on heart health. New research areas for the future, aimed at preventing, limiting, and reversing bad remodeling, are also discussed.

  • Agri 4.0 and the Future of Cyber-Physical Agricultural Systems

    • 1st Edition
    • Seifedine Kadry + 4 more
    • English
    Agri 4.0 and the Future of Cyber-Physical Agricultural Systems is the first book to explore the potential use of technology in agriculture with a focus on technologies that enable the reader to better comprehend the full range of CPS opportunities. From planning to distribution, CPS technologies are available to impact agricultural output, delivery, and consumption. Specific sections explore ways to implement CPS effectively and appropriately and cover digitalization of agriculture, digital computers to assist the processes of agriculture with digitized data and allied technologies, including AI, Computer Vision, Big data, Block chain, and IoT. Other sections cover Agri 4.0 and how it can digitalize, estimate, plan, predict, and produce the optimum agricultural inputs and outputs required for commercial purposes. The global team of authors also presents important insights into promising areas of precision agriculture, autonomous systems, smart farming environment, smart production monitoring, pest detection and recovery, sustainable industrial practices, and government policies in Agri 4.0.

  • Food Industry 4.0

    Emerging Trends and Technologies in Sustainable Food Production and Consumption
    • 1st Edition
    • Abdo Hassoun
    • English
    Developments in Food Quality and Safety Series is the most up-to-date resource covering trend topics such as Advances in the analysis of toxic compounds and control of food poisoning; Food fraud, traceability and authenticity; Revalorization of agrifood industry; Natural antimicrobial compounds and application to improve the preservation of food; Non-thermal processing technologies in the food industry; Nanotechnology in food production; and Intelligent packaging and sensors for food applications. Volume 4, Food Industry 4.0: Emerging Trends and Technologies in Food Production and Consumption covers several technologies (e.g., robotics, smart sensors, artificial intelligence, and big data) at different development and research levels in order to provide holistic multidisciplinary approaches that embrace simultaneously as many Industry 4.0 technologies as possible, reflecting the long journey of food from farm (or sea) to fork. Chapters explore automation, digitalization, and green technologies, besides food quality, food safety food traceability, processing and preservation 4.0. Topics such as smart sensors, artificial intelligence and big data revolution, additive manufacturing, and emerging food trends are also explored. The series is edited by Dr. José Manuel Lorenzo and authored by a team of global experts in the fields of Food Quality and Safety, providing comprehensive knowledge to food industry personals and scientists.

  • Translational Orthopedics

    • 1st Edition
    • Jeffrey A. Bakal + 4 more
    • English
    Translational Orthopedics: Designing and Conducting Translational Research covers the principles of evidence-based medicine and applies these principles to the design of translational investigations. Readers will come to fully understand important concepts, including case-control study, prospective cohort study, randomized trial, and reliability study. Medical researchers will benefit from greater confidence in their ability to initiate and execute their own investigations, avoid common pitfalls in translational orthopedics, and know what is needed in collaboration. Further, this title is an indispensable tool in grant writing and funding efforts.The practical, straightforward approach helps the aspiring investigator navigate challenging considerations in study design and implementation. The book provides valuable discussions of the critical appraisal of published studies in translational orthopedics, allowing the reader to learn how to evaluate the quality of such studies with respect to measuring outcomes and to make effective use of all types of evidence in patient care. In short, this practical guidebook will be of interest to every Medical Researcher or Orthopedist who has ever had a good clinical idea but not the knowledge of how to test it.

  • Falciparum Malaria

    Diagnostic Tools, Therapeutic Advances, and Future Opportunities
    • 1st Edition
    • Tabish Qidwai
    • English
    Falciparum Malaria: Diagnostic Tools, Therapeutic Advances, and Future Opportunities discusses the current state of therapeutic options for malaria, antimalarial drugs and drug targets. The book also covers recent progress in the development of vaccines and other approaches for malaria treatment, prevention and control and explores diagnostic tools and biomarkers. Sections examine potential biomarkers and their applications, molecular diagnostic tools, multi-omic approaches for the characterization of therapeutic action of potential new antimalarials, therapeutic advances in falciparum malaria, antimalarial drugs, targeting parasite apicoplast for antimalarial drug discovery, cellular and adjunctive therapies for malaria treatment, and future opportunities. With contributions from experts in the field, this book is an ideal resource for academics, researchers, graduates and industry engaged in malaria research, its diagnosis, and treatment.

  • Antioxidant Methods

    A Guideline for Understanding and Determining Antioxidant Capacity
    • 1st Edition
    • Francisco Avelino
    • English
    Antioxidant Methods: A Guideline for Understanding and Determining AntioxidantCapacity summarizes the importance of antioxidants as a class of compounds withinnumerous areas of science and technology. The chapters elucidate diverse methodologiesfor assessing the antioxidant capacity of an antioxidant, while also exploring the correlationbetween its structural attributes and overall performance. Chapters include descriptions ofprotocols used to measure antioxidant capacity by different methods, highlighting experimentalsteps, bottlenecks, expected outcomes, advantages, limitations, and more.This is the perfect reference for biomedical science researchers looking for the right methodfor determining antioxidant capacity through the structure and functionalities of the compound,as well as the mechanisms involved in the antioxidant action.

  • Intelligent Packaging

    Current Technologies and Applications
    • 1st Edition
    • English
    Intelligent Packaging: Current Technologies and Applications, Volume Six in the Developments in Food Quality and Safety series is the most up-to-date resource on topics such as Advances in the analysis of toxic compounds and control of food poisoning; Food fraud, traceability and authenticity; Revalorization of agrifood industry; Natural antimicrobial compounds and application to improve the preservation of food; Non-thermal processing technologies in the food industry; Nanotechnology in food production; and Intelligent packaging and sensors. This updated volume covers intelligent packaging by discussing the aspects of emerging technologies and strategies to obtain such packaging relevant to the development of traceable food products.Topics such as indicators, sensors, tracing devices, and intelligent packaging used in various food products, such as dairy, meat, fruits and vegetables are also explored. The series is edited by Dr. José Manuel Lorenzo and authored by a team of global experts in the fields of Food Quality and Safety, providing comprehensive knowledge to food industry personals and scientists.

  • Livestock Genome Editing Tools

    • 1st Edition
    • Kui Li + 1 more
    • English
    Livestock Genome Editing Tools introduces applications and improvements to a series of new genome editing techniques in livestock, such as pigs, cattle, and sheep. These tools include zinc finger nucleases (ZFN), transcription activator–like effector nucleases (TALEN), and the clustered regularly interspaced short palindromic repeats (CRISPR/Cas9) system, as well as the traditional gene targeting tools. The book also summarizes a series of genome editing–related techniques, including microinjection and somatic cell nuclear transfer.Written by international experts who have been working on livestock genetic editing field for more than 30 years, this book provides extensively theoretical and practical experience for readers to master the latest developments. This book explores the importance of research and application, as well as operation procedures, of livestock genetic editing tools. The writing of operation details makes this book an accessible read.This book is an important resource for researchers interested in genome-edited animals and scientists and technicians in breeding institutions and is also of interest to students major in animal reproduction and biological engineering.

  • Protein Digestion-Derived Peptides

    Chemistry, Bioactivity, and Health Effects
    • 1st Edition
    • Cristina Martinez-Villaluenga + 1 more
    • English
    Protein Digestion-Derived Peptides: Chemistry, Bioactivity, and Health Effects presents the latest international advances in fundamental and applied research on the impact of gastrointestinal digestion on the release of bioactive peptides from food sources.This book covers the fundamentals and applications of gastrointestinal digestion and absorption models as well as the impact of food matrices, their components and protein characteristics, and peptide bioactivity, bioaccessibility, and bioavailability. Moreover, the book expands coverage in vitro and in vivo approaches to simulate gastrointestinal digestion of food proteins and absorption models to evaluate the bioaccessibility and bioavailability of released peptides.Developed for nutrition researchers, food scientists, and pharmaceutical scientists, this book is a welcomed resource for those who wish to understand the impact of peptides on chronic disease.

  • Advances in Agronomy

    • 1st Edition
    • Volume 185
    • English
    Advances in Agronomy, Volume 185, the latest release in this leading reference on agronomy, contains a variety of updates and highlights new advances in the field, each written by an international board of authors.

  • Advanced Imaging in Ischemic and Hemorrhagic Stroke, An Issue of Neuroimaging Clinics of North America

    • 1st Edition
    • Volume 34-2
    • Joseph J. Gemmete
    • English
    In this issue of Neuroimaging Clinics, guest editors Drs. Joseph Gemmete and Zachary Wilseck bring their considerable expertise to the topic of Advanced Imaging in Ischemic and Hemorrhagic Stroke. Top experts in the field discuss metabolic imaging such as PET, in vivo O17 MRS imaging, quantitative sodium MR imaging, pharmacological MRI (pHMRI), dual-energy CT, vessel wall imaging, and more.

  • Microbial Biofilms

    Role in Human Infectious Diseases
    • 1st Edition
    • Mukesh Kumar Yadav + 2 more
    • English
    Microbial biofilms are serious problem in medical settings as they are associated with significant mortality and morbidity. Infection related to biofilms not only increases recovery time, but also escalates the cost of disease management. Biofilms are intrinsically resistant to antibiotics and evade human defense mechanisms. In addition, the close proximity of microbes within biofilms promotes genetic transformation, facilitating the acquisition of antibiotic-resistant genes and leading to an increased prevalence of diseases associated with resistance. Fortunately, with advances in science and technology, novel strategies are being utilized to mitigate the impact of biofilms on human health.Microbial Biofilms: Role in Human Infectious Diseases focuses on new and emerging concepts in microbial biofilm research. It explores topics such as the mechanisms of biofilm formation, biofilm-induced pathogenesis, biofilm detection and diagnosis, gene exchange within biofilms, strategies to control microbial biofilms, and the burden of biofilm-associated infections. Additionally, the book highlights the various antibiofilm strategies, such as surface coating, signal quenching, novel compounds that can be translated to curb biofilm-associated infections, and the escalation of antimicrobial resistance determinants.

  • Liposomes in Drug Delivery

    What, Where, How and When to deliver
    • 1st Edition
    • Sophia G. Antimisiaris
    • English
    Liposomes in Drug Delivery: What, Where, How and When to Deliver is a concise, well-structured reference covering all the important issues related to the potential of this technology. Organized to provide practical information to researchers from any discipline with a particular therapeutic or bio-active substance to deliver, this book helps readers understand if liposomes can be of benefit for their particular need, what is the best type of liposome to use according to what needs to be delivered, where/when to deliver it, and how to design/prepare/chara... liposome properties for a particular application.The book is structured in Four parts. The first covers in a concise but in-depth way, what liposomes are, which are the liposome types, advantages/disadvant... and what is their stability, characterization methods, in vitro stability, and in vivo fate after different administration methods (routes). The second part focuses on the different mechanisms for liposomal drug delivery. Methodologies/techno... for manipulation of liposome structure/properties in order to design liposomes for particular delivery applications. Specific roadmaps for liposome design are discussed, including components to incorporate in liposomes for specific types of encapsulated molecules or specific routes of administration. The third part covers liposome applications for drug delivery. It focuses on specific delivery considerations for particular diseases. Finally, the fourth part covers methods of liposome fabrication.

  • Sinusoidal Cells in Liver Diseases

    Role in their Pathophysiology, Diagnosis, and Treatment
    • 1st Edition
    • Jordi Gracia-Sancho
    • English
    Sinusoidal Cells in Liver Diseases: Role in their Pathophysiology, Diagnosis, and Treatment provides a state-of-the-art review on recent advances surrounding the role of liver sinusoidal cells (LSECs, HSCs, macrophages, and other non-parenchymal cells) in acute and chronic liver diseases. Coverage emphasizes disease pathophysiology, novel mechanisms, unmet clinical questions, development of biomarkers, and treatment opportunities. By focusing on the role of sinusoidal cells in human liver diseases, this reference provides a comprehensive overview of the role of sinusoidal cells in acute and chronic liver diseases, in its pathophysiology and mechanisms, and in the development of novel biomarkers and new therapeutics.Cells of the liver vasculature play an essential role in the pathophysiology of acute and chronic liver diseases and are considered key therapeutic targets to treat most of human hepatopathies. Coverage in this reference includes the phenotypic changes occurring in liver vascular cells and how cells contribute to the development of microcirculatory dysfunction, fibrosis, inflammation, and liver failure.

  • Mass-Action Law Dynamics Theory and Algorithm for Translational and Precision Medicine Informatics

    • 1st Edition
    • Ting-Chao Chou
    • English
    “Mass-Action Law Dynamics Theory and Algorithm for Translational and Precision Medicine Informatics” provides a comprehensive overview and update of the mass-action law-based unified dose-effect biodynamics, pharmacodynamics, bioinformatics, and the combination index theorem for synergy definition (MAL-BD/PD/BI/CI). Contents advocate the fundamental MAL-PD/BI/CI/BI principle for biomedical R&D, clinical trials protocol design computerized data analysis, illustrates the MAL-dynamics theory with sample analysis, and includes data entry and automated computer report print-outs. In 11 sections “Mass-Action Law Dynamics Theory and Algorithm for Translational and Precision Medicine Informatics” leads the reader from an introduction and overview, to trial protocols and MAL-PD/CI approach for biomedical R&D in vitro and in animals. It describes the current Landscape of International FDA Drug Evaluation, Clinical Pharmacology, and Clinical Trials Guidance. This is a valuable resource for biomedical researchers, healthcare professionals, and students seeking to harness the power of data informatics in precision medicine.

  • Cranial Surgery - Part 1

    • 1st Edition
    • Volume 284
    • Jeremy Christopher Ganz
    • English
    This is a study of the evolution of the principles and techniques of cranial surgery from Hippocrates to the nineteenth century. The methods of conveying information by text and image are considered.

  • Secondary Headaches, An Issue of Neurologic Clinics

    • 1st Edition
    • Volume 42-2
    • Randolph W. Evans
    • English
    In this issue of Neurologic Clinics, guest editor Randolph W. Evans brings his considerable expertise to the topic of Secondary Headaches.

  • Pathophysiology, Risk Factors, and Management of Chronic Heart Failure

    • 1st Edition
    • Ram B. Singh + 3 more
    • English
    Chronic Heart Failure: Pathophysiology, Risk Factors, and Mechanisms aims to provide an inclusive overview on Chronic Heart Failure (CHF).This book is focused on the epidemiology, classification, molecular mechanisms, pathophysiology, causes, identification and interactions of heart failure. It will explain the uncertainties and issues in Heart Failure by helping readers understand the physiopathology of CHF in the light of behavioural risk factors. 2D and 3D speckle tracking echocardiography have been used to quantify regional alterations of longitudinal strain and area strain, through their polar projection, which allows a further evaluation of both the site and extent of myocardial damage. The analysis of strain can identify subclinical cardiac failure (myocyte remodelling) which is a major issue in CHF. Myocardial Strain, measure by speckle tracking echocardiography, is frequently attenuated in these conditions and can be utilized for the evaluation of disease progression and the effect of therapeutic interventions as well as prevention because it could be a manifestation of behavioural risk factors.This title will function as an essential reference to both researchers and practicing clinicians, proposing novel methods of research by using behavioural and environmental risk factors as intervention agents, as well as discussing deficiency in the present approaches in management of HF and proposing new methods of early diagnosis and therapies for the clinical management of CHF.

  • Microbiome-Based Decontamination of Environmental Pollutants

    • 1st Edition
    • Ajay Kumar + 2 more
    • English
    Microbiome-Based Decontamination of Environmental Pollutants explores the complex interactions of plant-associated microbiomes, providing insights into the pressing challenges of managing environmental resources such as soil, water, and waste. Analysis has shown a formidable potential based in the network interactions between plant microbiota and environmental contaminants. This book presents insights into the potential exploitation of these plant-associated microbial functions. This volume in the Plant and Soil Microbiome series summarizes microbiological aspects of environmental management from the basics to advanced theoretical as well as practical aspects of microbial-based approaches.The physical and chemical changes caused by pollution of an ecosystem can occur rapidly, significantly impacting the functionality of ecosystem services in that environment. Environmental contamination poses and increasingly global challenge through direct and indirect adverse impacts on the climate, soil productivity and the health concerns of human beings. Traditional remediation techniques are not consistently feasible in mitigating environmental contaminants challenges in terms of cost-effectiveness, limited land resources and toxic residual products. The use of plant-associated microbes as part of a network of tools opens a new door to explore an alternative, eco-friendly and economical technology to mitigate the challenges of environmental contamination.

  • Techniques for Biochemical Analysis

    • 1st Edition
    • Khursheed Hussain + 3 more
    • English
    Techniques for Biochemical Analysis provides researchers with a practical guide for investigating a variety of different biomolecules. It includes a range of tried and tested protocols, outlining the principles upon which each technique is founded, as well as providing instructions on equipment setup and use, buffer preparation, reagents required, safety considerations and analysis of findings. Beginning with an introduction to biochemistry and laboratory procedures, the book moves on to specific methods focused on investigation of carbohydrates, proteins, enzymes, plant hormones, minerals, amino acids, and more.The large range of protocols covered in this foundational, how-to reference are interdisciplinary and adaptable to a variety of areas, making this an ideal resource for researchers across various fields, including biochemistry, molecular biology, medical sciences, plant physiology, agriculture, and related subjects.

  • COVID-19’s Consequences on the Cardiovascular System

    Immediate, Intermediate, and Long-Term Complications
    • 1st Edition
    • Fabian Sanchis-Gomar + 1 more
    • English
    Scientific evidence demonstrates that while COVID-19 primarily affects the lungs, it also affects multiple organs, particularly the cardiovascular system; its most common complications are arrhythmia, cardiac injury, fulminant myocarditis, heart failure, and pulmonary embolism. COVID-19’s Consequences on the Cardiovascular System: Immediate, Intermediate, and Long-Term Complications covers all aspects related to the interplay between SARS-COV-2 infection and the cardiovascular system, from bench to bedside and from acute infection to long-term complications.Writte... by a team of experts, this book is a one-stop-shop reference for healthcare professionals and researchers who require a comprehensive view of the deleterious effects of COVID-19 on the cardiovascular system. It discusses the relationship of cardiovascular risk factors with COVID-19 prognosis. It offers further insights into the biomarkers that currently make it possible to predict and monitor the evolution of the disease at the cardiovascular level.

  • Diseases and Health Consequences of Air Pollution

    Volume 3: Air Pollution, Human Health, and the Environment
    • 1st Edition
    • Mohammad Hadi Dehghani + 3 more
    • English
    Diseases and Health Consequences of Air Pollution, Volume Three, Air Pollution, Human Health, and the Environment is part of a three-volume series. This volume focuses on epidemiological studies and diseases attributed to ambient and indoor air pollutants. It opens with an overview of diseases and health consequences due to air pollution. The chapters discuss health conditions such as respiratory issues, cardiovascular diseases, hypertension and blood pressure, diabetes, nervous system, brain, cancer, stroke—cerebrovascul... disease, and skin disease that are linked to exposure to indoor and outdoor air pollutants.The book also evaluates the health cost and economic burden of air pollution and offers risk management and solutions to mitigate the health implications of indoor and ambient air pollution. This book provides a single source solution and the latest information about the diseases attributed to air pollutants and their health impact. It will be a valuable reference for academicians, researchers, and students in environmental health, public health, and occupational health, as well as environmental engineers, meteorologists, epidemiologists, medical researchers, and environmental toxicologists.

  • Organizers in Development

    • 1st Edition
    • Volume 157
    • English
    Organizers in Development, Volume 157 in the Current Topics in Developmental Biology series, highlights new advances in the field, with this new volume presenting interesting chapters on topics such as The organizer: what it meant, and means, to developmental biology, Organizers/signaling regions that pattern the limb, Organizers/signaling regions in the branchial arches, The notochord/floor plate as a possible organizer, Transport and gradient formation of Wnt and Fgf in the early zebrafish gastrula, and more.

  • Health and Environmental Effects of Ambient Air Pollution

    Volume 1: Air Pollution, Human Health, and the Environment
    • 1st Edition
    • Mohammad Hadi Dehghani + 3 more
    • English
    Health and Environmental Effects of Ambient Air Pollution is part of a series of three volumes for Air Pollution, Human Health, and the Environment. Volume 1 discusses the adverse consequences of ambient air pollutants on human health, animals, plants, and structures.This book examines the production of ambient air pollutants in the environment. It begins with an overview of the classifications, sources, and occurrences of outdoor air pollutants. This book covers meteorological, climate, and topographical factors affecting air pollution, discusses how urbanization and industrialization affect air quality, and explores how climate conditions like global warming, acid rain, and airborne particulate matter impact human health. It also looks at epidemiology studies and socioeconomic aspects of outdoor air pollution, estimating health and cost effects, air quality indices, guidelines, standards, and information networks of ambient air pollutants. With contributors from experts in the field, this book is a valuable reference for academicians, researchers, and students in environmental health, public health, and occupational health, as well as environmental engineers, meteorologists, epidemiologists, medical researchers, and environmental toxicologists.

  • Health Effects of Indoor Air Pollution

    Volume 2: Air Pollution, Human Health, and the Environment
    • 1st Edition
    • Mohammad Hadi Dehghani + 3 more
    • English
    Health Effects of Indoor Air Pollution, Volume Two, Air Pollution, Human Health, and the Environment is part of a three volume series. This volume covers the various classifications of indoor air pollutants and discusses the health impact of indoor pollutants, such as gaseous pollutants and particulate matter. It also examines epidemiological studies related to different air pollutants on health and the workplace. This book begins with an overview of classifications, sources, and occurrences of indoor air pollutants. It also examines the environmental and health impacts due to organic and inorganic air pollutants and how to mitigate them through exposure and risk management.Other sections explore “sick building syndrome,” which causes acute health and discomfort that appears to be linked to time spent in a building. Recent trends and control strategies for occupation exposure due to poor indoor air quality in industrial and nonindustrial workplaces to human health are also covered. This book is a valuable reference for academicians, researchers, and students in environmental health, public health, and occupational health, as well as environmental engineers, meteorologists, epidemiologists, medical researchers, and environmental toxicologists.

  • Fundamental Principles of Oxidative Stress in Metabolism and Reproduction

    Prevention and Management
    • 1st Edition
    • Faiza Alam + 1 more
    • English
    Fundamental Principles of Oxidative Stress in Metabolism and Reproduction: Prevention and Management is a comprehensive resource for anyone needing awareness and recognition of oxidative stress as a basic component of disease to determine the precise treatment plan considering the cause of the disease. It describes the effects of oxidative stress in the human body, the detection of metabolic changes, psychological impact and effect on reproductive outcomes. In addition, it discusses alterations at the cellular level occurring due to oxidative stress along with the genetic aspects involved in its pathogenesis.

  • Low-Temperature Processing of Food Products

    Unit Operations and Processing Equipment in the Food Industry
    • 1st Edition
    • Seid Mahdi Jafari + 1 more
    • English
    Low-Temperature Processing of Food Products, Volume Seven in the Unit Operations and Processing Equipment in the Food Industry series, explains the processing operations and equipment necessary for low-temperature processing of different food products. These processes are very important for achieving favorable sensory properties and energy usage. Divided in four sections, “Basics of low-temperature processing “, “Different types of cooling and freezing systems”, “Application of freezing in the food industry”, and “Design, control and efficiency of freezers”, all chapters emphasize basic texts relating to experimental, theoretical, computational, and/or applications of food engineering principles and relevant processing equipment to low-temperature unit operations.Written by experts in the field of food engineering, in a simple and dynamic way, this book targets industrial Engineers working in the field of food processing and within food factories to make them more familiar with the particular food processing operations and equipment.

  • Neurologie
    • 14th Edition
    • Jean Cambier + 3 more
    • French
    L’ouvrage• Devenu un « classique » dès sa première édition, l’Abrégé de neurologie présente, de façon claire, pratique et complète, les troubles neurologiques selon une approche sémiologique en s’appuyant sur l’anatomie et la physiologie et en intégrant les nouvelles connaissances apportées par la neuropsychologie et la neurogénétique. L’ouvrage décrit les affections neurologiques les plus fréquentes et propose une stratégie pour le diagnostic neurologique à la lumière de l’imagerie médicale et des explorations électrophysiologique... et métaboliques.• Cette 14e édition est entièrement revue et actualisée, en fonction notamment des évolutions des thérapeutiques et des méthodes diagnostiques. La structure de l’ouvrage a également été révisée, pour une meilleure lisibilité, en tenant compte des développements de certains sujets, et l’ajout de nouveaux chapitres : « Cervelet – Ataxies cérébelleuses », « Mouvements anormaux » et « Émotion, motivation, comportement et cognition ».• Cette nouvelle édition présente ainsi les connaissances actuelles en neurologie tout en conservant l’approche qui a fait la réputation de cet ouvrage : la place donnée la neurologie clinique et l’intégration de la sémiologie dans l’organisation structurelle et physiologique du système nerveux, dans le souci de les rendre compréhensibles pour tous.Le publicCet abrégé s’adresse aux étudiants de 2e et 3e cycles de médecine. Il intéressera également les neurologues et tous les praticiens confrontés à des symptômes ou à des troubles neurologiques.Les auteursJean Cambier † était membre de l’Académie de médecine et professeur de clinique neurologique.Maurice Masson est neurologue, professeur des universités.Catherin... Masson est neurologue, praticien hospitalier.Henri Dehen † était professeur de neurologie.

  • Exosomal RNA

    Role in Human Diseases and Therapy
    • 1st Edition
    • Debalina Bhattacharya + 2 more
    • English
    Exosomal RNA: Role in Human Diseases and Therapy provides an in-depth study of exosomes and their RNA in the context of a variety of diseases. The book explores the diagnostic and therapeutic potential of exosomal RNA as biomarkers across a range of different conditions, including cancer, type 2 diabetes, cardiovascular and renal disease, as well as bacterial infections and tissue repair. The link between exosomal RNA expression and neurodegenerative disease is also explored. The book goes on to share the significance of exosomal RNA in preserving cellular function, with special attention given to their role in the autophagy process.This book also gives an overview of the isolation, characterization, and potential applications of exosomal RNA, providing researchers with an understanding of how they can be manipulated and utilized for the treatment of various diseases and conditions. This is an ideal reference for researchers in the field of molecular biology, cell biology, and related fields, as well as those involved in the development of therapeutics and personalized medicine.

  • A Multidisciplinary Approach to Managing Swallowing Dysfunction in Older People

    • 1st Edition
    • Pere Clave´ + 1 more
    • English
    A Multidisciplinary Approach to Managing Swallowing Dysfunction in Older People provides comprehensive coverage on oropharyngeal dysphagia (OD), focusing on older patient phenotypes. The book provides the knowledge needed for translational researchers and professionals to aid in the detection, diagnosis, treatment and management of OD, ultimately improving patient quality of life. OD has been recently considered a geriatric syndrome because of its high prevalence, the increase of life-expectancy and the need to be managed by a multidisciplinary approach. This reference takes a novel approach to OD, covering all aspects as a geriatric syndrome, examining a complicated and multi-level topic in a succinct way. Contents include the most innovative information available in current literature combined with practical applications to improve the diagnosis and treatments of OD as a geriatric syndrome. This is the perfect reference for translational researchers, physicians and healthcare professionals dealing with OD.

  • Animal Models of Disease Part A

    • 1st Edition
    • Volume 185
    • English
    Animal Models of Disease, Part A, Volume 185 in the Methods in Cell Biology series, highlights advances in the field, with this new volume presenting interesting chapters on a variety of timely topics, including New mouse model to study aneurysm development, Mouse Model of Secondary Cystic Echinococcosis, Modelling childhood cancer in Drosophila, Analysis of immunohistomorpholog... changes in the colonic mucosa in a high-saturated fat and high-cholesterol fed streptozotocin/nicot... diabetic rat model, Establishment of an orthotopic Glioblastoma mouse model for preclinical studies, Lateral Fluid Percussion Injury as a Model for Traumatic Brain Injury, Ovarian and colorectal peritoneal carcinomatosis in mouse models, and more.Other chapters cover Genetically engineered mouse model of hepatocellular carcinoma, Radiotherapy protocol in cancer mouse models, Using C. elegans as a model for neurodegenerative diseases: Methodology and evaluation, Methodology for the induction of myocardial infarction and cardiac function evaluation, Behavioral assessment of fine socio-sexual olfactory cues detection in a mouse model of neurodegeneration, Heat shock and thermotolerance in Caenorhabditis elegans: an overview of laboratory techniques, and Using the model cestode Taenia crassiceps for the study of cysticercosis.

  • Radiomics and Radiogenomics in Neuro-Oncology

    An Artificial Intelligence Paradigm - Volume 1: Radiogenomics Flow Using Artificial Intelligence
    • 1st Edition
    • Sanjay Saxena + 1 more
    • English
    Radiomics and Radiogenomics in Neuro-Oncology: An Artificial Intelligence Paradigm, Volume One: Radiogenomics Flow Using Artificial Intelligence broadly encompasses the study of life-threatening brain and spinal cord malignancies, including primary lesions and those metastasizing to the central nervous system. Radiomics is an approach to medical imaging used to extract many quantitative imaging features using different data characterization algorithms, while radiogenomics, which has recently emerged as a novel mechanism in neuro-oncology research, focuses on the relationship of imaging phenotype and genetics of cancer. Sections in this book discuss several AI approaches that have been applied to conventional and advanced medical imaging data. These AI-based R-n-R tools have the potential to stratify patients into more precise initial diagnostic and therapeutic pathways and permit better dynamic treatment monitoring in this period of personalized medicine. While extremely promising, the clinical acceptance of R-n-R methods and approaches will primarily hinge on their resilience to non-standardization across imaging protocols and their capability to show reproducibility.

  • The neurobiology of Alcohol Use Disorder

    Neuronal mechanisms, current treatments and novel developments
    • 1st Edition
    • Volume 175
    • English
    The Mechanisms Behind Developing Dependence, Sub-groups, and Novel Approaches to Treatment, Volume 174 in the Neurobiology of Alcohol Abuse series, highlights new advances in the field, with this new volume presenting interesting chapters on topics such as Substitution therapy in alcohol treatment, with a focus on mechanisms and possibilities, Designing and analyzing studies on treatments for alcohol dependence, The harm reduction approach for treatment of alcohol dependence, Current treatments for alcohol dependence, with a suggested focus on mechanisms and possibilities, Metabolomics in relation to alcohol dependence with focus on possibilities for precision medicine, and Repurposing drugs for treatment of alcohol dependence.

  • Heart Development and Disease

    • 1st Edition
    • Volume 156
    • English
    Heart Development and Disease, Volume 156 in the Current Topics in Developmental Biology series, highlights new advances in the field, with this new volume presenting interesting chapters including Macrophages during heart valve development, Computational models of cardiovascular biology, Mechanisms of early sarcomere assembly, Role of RNA binding proteins during heart development and disease, Early heart development and morphogenesis, PSC models for development and disease, ECM or SHF development, Role of metabolism during heart development, Cellular ploidy in cardiac biology, and Genetics of CHD in the human population.

  • From Brain Dynamics to the Mind

    Spatiotemporal Neuroscience
    • 1st Edition
    • Georg Northoff
    • English
    From Brain Dynamics to the Mind: Spatiotemporal Neuroscience explores how the self and consciousness is related to neural events. Sections in the book cover existing models used to describe the mind/brain problem, recent research on brain mechanisms and processes and what they tell us about the self, consciousness and psychiatric disorders. The book presents a spatiotemporal approach to understanding the brain and the implications for artificial intelligence, novel therapies for psychiatric disorders, and for ethical, societal and philosophical issues. Pulling concepts from neuroscience, psychology and philosophy, the book presents a modern and complete look at what we know, what we can surmise, and what we may never know about the distinction between brain and mind.

  • Molecular Impacts of Nanoparticles on Plants and Algae

    • 1st Edition
    • Huseyin Tombuloglu + 4 more
    • English
    Molecular Impacts of Nanoparticles on Plants and Algae covers molecular mechanisms of plants/algae related to cellular uptake, translocation of nanoparticles, and genome, transcriptome, proteome, and metabolome responses against it. The book introduces readers to state-of-the-art developments and trends of nanoparticles and plants/algae including interactions of nanoparticles with biological compounds in vitro. Nanoscience and nanotechnology have rapidly been developed in the last few decades, and they have a wide range of applications in industry, medicine, food, and agriculture. In agriculture, nanoparticles (NPs) have successfully been used for growth regulation, crop protection and improvement. This book presents the most recent findings on nanoparticle and plant/algae interaction by focusing on molecular response mechanisms at genome, transcriptome, proteome and metabolome levels. In addition, uptake and translocation mechanism of nanoparticles are assessed both in plant and algae. Throughout this book, the latest developments and discoveries are highlighted, along with open problems and future challenges in molecular mechanisms of plants/algae as a response of nanoparticles.

  • Emerging Contaminants

    Sustainable Agriculture and the Environment
    • 1st Edition
    • Arpna Kumari + 4 more
    • English
    Emerging Contaminants: Sustainable Agriculture and the Environment provides a thorough, comprehensive, and interdisciplinary overview of the many categories of emerging pollutants, including pharmaceuticals, insecticides, personal care items, and industrial chemicals, that are currently impacting the environment. With insights into the exposure associated consequences on crops and edible plants, this book is designed to enable foundational understanding as the basis for future research, as well as providing practical application guidance in current environments.Water resource shortages, declining arable land, environmental contamination with different exiting or ECs, shortcomings in the procedures for protecting cultivated land, and inefficiencies in the management of land tenure rights continue to pose challenges for agricultural sustainable development around the world. This book focuses on the impacts of ECs on sustainable agricultural production and explores possible response approaches.Following an introduction to environmental contaminants, this book discusses their fate in soils, presents the most up-to-date analytical methods for detecting them in different environmental matrices, and addresses current regulatory restrictions. Finally, this book ends with a chapter dedicated to conclusions and future perspectives.Emergin... Contaminants is an ideal resource for researchers and professionals from a variety of sciences including agricultural, plant, and environmental.

  • Microbial Technology for Agro-Ecosystems

    Crop Productivity, Sustainability, and Biofortification
    • 1st Edition
    • Vivek Kumar + 1 more
    • English
    Microbial Technology for Agro-Ecosystems: Crop Productivity, Sustainability, and Biofortification describes the application of competent microbes in plant growth promotion, nutrient management and recycling from molecular perspectives. Understanding of molecular mechanism of Microbial diversity in association with plant roots is very imperative for plant health and ecosystem equilibrium.

  • Public Health and Toxicology Issues in Drug Research, Volume 2

    Toxicity and Toxicodynamics
    • 1st Edition
    • Rakesh K. Tekade
    • English
    Public Health and Toxicology Issues in Drug Research: Toxicity and Toxicodynamics, Volume Two examines implications on public health and the impact of pharmaceuticals, chemical and food toxicants, dietary phytochemicals, and medical treatments. The book cover topics on pharmacokinetics and toxicokinetics, such as population pharmacokinetics/tox... the design of toxicokinetic studies, and the use of toxicokinetic data in preclinical safety assessments. In addition, it investigates the health effect caused by the bioaccumulation of pharmaceutical and personal care products and the impact of drug-induced toxicity on different systems of the body.Final sections discuss the mechanistic pathways of food toxicants and illustrate the molecular mechanisms of the chemopreventive role of dietary phytochemicals. Ethical, legal, societal, and professional issues in toxicology round off coverage, making this a valuable resource for anyone interested in learning more about the health impact and public health issues related to the toxicity of pharmaceuticals, dietary supplements, personal care products, and medical treatments.

  • Advanced Vaccination Technologies for Infectious and Chronic Diseases

    A guide to Vaccinology
    • 1st Edition
    • Vasso Apostolopoulos + 2 more
    • English
    Advanced Vaccination Technologies for Infectious and Chronic Diseases is a comprehensive guide that delves into the intricate details of vaccine design, development across various platforms, and the path to commercialization. This book provides an introductory overview of vaccines, covering various types, developmental methodologies, delivery systems, adjuvants, immunization, and measurement of vaccine efficacy. It also showcases examples of vaccine research efforts targeting infectious diseases, autoimmune disorders, and cancer. The book concludes by exploring cutting-edge advances in proteogenomics, immunopeptidomics, and future vaccine technologies.The primary objective of this book is to inform a broad scientific audience about the fundamental concepts underlying vaccine and immunology. Further, it serves as an invaluable reference for understanding the critical steps in the journey from discovery to regulatory processes for human clinical trials, addressing common misconceptions and presenting factual information about vaccinations. Advanced Vaccination Technologies for Infectious and Chronic Diseases is a requisite reference for occupational health professionals whose roles involve supervision of immunization programs such as those working within the National Health Service, some sectors of higher education, or the pharmaceutical industry. It also caters to those researchers engaged in vaccine development and all who want to learn the processes involved from laboratory research to final product.

  • Novel Formulations and Future Trends

    Recent and Future Trends in Pharmaceutics, Volume 3
    • 1st Edition
    • Amit Kumar Nayak + 1 more
    • English
    Novel Formulations and Future Trends, Volume Three in the Recent and Future Trends in Pharmaceutics series, explores aspects of pharmaceutics with an original approach focused on technology, novelties and future trends. It discusses the most important developments in drug delivery, including important and exciting areas such as mucosal, implantable, transdermal, gastroretentive, vaccine and targeted drug delivery systems. The field of pharmaceutics is highly dynamic and rapidly expanding day-by-day so it demands a variety of amplified efforts for designing and developing pharmaceutical processes and formulation strategies. This is an essential reference for researchers in academia and industry as well as advanced graduate students.New technologies are also explored including 3D printing and computational pharmaceutics.

  • Microbial Diversity in the Genomic Era

    Functional Diversity and Community Analysis
    • 2nd Edition
    • Surajit Das + 1 more
    • English
    Microbial Diversity in the Genomic Era: Functional Diversity and Community Analysis, Second Edition presents techniques used for microbial taxonomy and phylogeny, along with their applications and respective strengths and challenges. The book incorporates recently developed biosystematics methods and approaches to assess microbial taxonomy, with suitable recommendations for where to apply them across the range of bacterial identification and infectious disease research. Sections provide a broad overview of microbial genomics research and microbiome directed medicine and update on molecular tools for microbial diversity research, extremophilic microbial diversity, functional microbial diversity across application areas, microbial diversity and infectious disease research, and future directions. Step-by-step methodologies are provided for key techniques, along with applied case studies that break down recent research studies into practical components, thus illuminating pathways for new studies across the field.

  • Computational Intelligence in Protein-Ligand Interaction Analysis

    • 1st Edition
    • Bing Wang + 2 more
    • English
    Computational Intelligence in Protein-Ligand Interaction Analysis presents computational techniques for predicting protein-ligand interactions, recognizing protein interaction sites, and identifying protein drug targets. The book emphasizes novel approaches to protein-ligand interactions, including machine learning and deep learning, presenting a state-of-the-art suite of skills for researchers. The volume represents a resource for scientists, detailing the fundamentals of computational methods, showing how to use computational algorithms to study protein interaction data, and giving scientific explanations for biological data through computational intelligence. Fourteen chapters offer a comprehensive guide to protein interaction data and computational intelligence methods for protein-ligand interactions.

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