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Elsevier

Books in Life sciences

  • Unveiling the History of Transplantation

    An Illustrated Review of the Boundaries, Fantasies and Realities
    • 1st Edition
    • Shi Chen
    • English
    Unveiling the History of Transplantation: An Illustrated Review of the Boundaries, Fantasies and Realities covers the key international figures involved in organ transplantation and related fields. It includes a discussion of the contributions of many Nobel Prize winners in Physiology and Medicine. The book introduces the whole process of transplantation and the latest research progress of cell, tissue, and organ transplantation: from initial exploration to maturity and on to widespread application. A key feature of this resource is that it includes a large number of unique historical photos and material related to organ transplantation as collected by the author from libraries worldwide.

  • mRNA Therapeutics

    Foundations, Innovations, and Clinical Applications
    • 1st Edition
    • Anya Hillery
    • English
    mRNA Therapeutics: Foundations, Innovations and Clinical Applications aims to provide a comprehensive text that covers all aspects of mRNA therapeutics, from the foundational science that underpins this disruptive new drug class, through the scientific and technological breakthroughs crucial for therapeutic success, to the current clinical applications and the innovative advances driving future directions. The book begins with foundational knowledge covering mRNA biology, the immune system, and vaccines. The second section addresses the major challenges associated with mRNA as a therapeutic modality, and the molecular engineering innovations and delivery technologies that have allowed these hurdles to be largely overcome. The third section describes the current and future clinical applications of mRNA therapeutics that are transforming, or are poised to transform, medicine and health. This includes the use of mRNA vaccines for COVID-19 and other infectious diseases, as well as mRNA's role in revolutionizing cancer immunotherapy, covering immunostimulants, cancer vaccines including personalized neoantigen vaccines, and CAR T cell technologies. Additional chapters describe the use of mRNA therapeutics for protein replacement therapy and gene-editing, as well as newer mRNA constructs, including self-amplifying mRNA. The final section addresses the safety and regulatory considerations of mRNA therapeutics, along with broader cultural issues including vaccine hesitancy, global vaccine inequality, and pandemic preparedness. Currently, mRNA texts either provide personal accounts from key players involved in COVID-19 vaccine development, with limited scientific depth, or focus on highly specialized, more esoteric applications of mRNA in advanced molecular biology. This book aims to bridge this gap by providing a scientifically rigorous and wide-ranging exploration of mRNA's role in therapeutics. This pioneering textbook serves as a vital addition to the academic canon, providing an essential tool for the current and next generation of students, scientists, researchers and professionals in a wide variety of related disciplines including molecular biology, biomedical engineering, pharmaceutical science, oncology, and the health sciences.

  • Artificial Intelligence for Drug Product Lifecycle Applications

    • 1st Edition
    • Alberto Pais + 3 more
    • English
    Artificial Intelligence for Drug Product Lifecycle Applications explains the use of artificial intelligence (AI) in drug discovery and development paths, including the clinical and postapproval phases. This book gives methods for each of the drug development steps, from the fundamentals to postapproval drug product. AI is a synergistic assembly of enhanced optimization strategies with particular applications in pharmaceutical development and advanced tools for promoting cost-effectiveness throughout the drug lifecycle. Specifically, AI brings together the potential to improve drug approval rates, reduce development costs, get medications to patients faster, and help patients comply with their treatments.Accelerat... pharmaceutical development and drug product approval rates will enable larger profits from patent-protected market exclusivity. This book offers the tools and knowledge to create the right AI strategy to extend the landscape of AI applications across the drug lifecycle. It is especially useful for pharmaceutical scientists, health care professionals, and regulatory scientists, as well as advanced students and postgraduates actively involved in pharmaceutical product and process development involving the use of artificial intelligence in drug delivery applications.

  • Biomechatronics

    • 2nd Edition
    • Marko B. Popovic
    • English
    Biomechatronics is rapidly becoming one of the most influential and innovative research directions defining the 21st century. The second edition Biomechatronics provides a complete and up-to-date account of this advanced subject at the university textbook level. This new edition introduces two new chapters – Animals Biomechatronics and Plants Biomechatronics – highlighting the importance of the rapidly growing world population and associated challenges with food production. Each chapter is co-authored by top experts led by Professor Marko B. Popovic, researcher and educator at the forefront of advancements in this fascinating field. Starting with an introduction to the historical background of Biomechatronics, this book covers recent breakthroughs in artificial organs and tissues, prosthetic limbs, neural interfaces, orthotic systems, wearable systems for physical augmentation, physical therapy and rehabilitation, robotic surgery, natural and synthetic actuators, sensors, and control systems. A number of practice prompts and solutions are provided at the end of the book. The second edition of Biomechatronics is a result of dedicated work of a team of more than 30 contributors from all across the globe including top researchers and educators in the United States (Popovic, Lamkin-Kennard, Herr, Sinyukov, Troy, Goodworth, Johnson, Kaipa, Onal, Bowers, Djuric, Fischer, Ji, Jovanovic, Luo, Padir, Tetreault), Japan (Tashiro, Iraminda, Ohta, Terasawa), Sweden (Boyraz), Turkey (Arslan, Karabulut, Ortes), Germany (Beckerle and Wiliwacher), New Zealand (Liarokapis), Switzerland (Dobrev), and Serbia (Lazarevic).

  • Forest Fungi

    Biodiversity, Conservation, Mycoforestry and Biotechnology
    • 1st Edition
    • Ahmed M. Abdel Azeem + 3 more
    • English
    Forest Fungi: Biodiversity, Conservation, Mycoforestry and Biotechnology explores sustainable option aspects of forest fungal research, from the selection of hosting plants, isolation, identification, fermentation, identification of secondary metabolites, omics-tools for better understanding the plant–fungus Interactions. Forests are the world’s greatest repository of terrestrial biomass, soil carbon and biodiversity. They provide a variety of provisioning, supporting, regulatory and cultural ecosystem services, which are crucial for the survival of human beings. Fungi play key roles in forest ecosystems as mutualists, saprobes and pathogens.

  • Self-powered Sensors

    A Path to Wearable Electronics
    • 1st Edition
    • Rajesh Kumar Dhanaraj + 4 more
    • English
    Self-powered Sensors: A Path to Wearable Electronics features recent developments in chemical, photonic, pharmaceutical, microbiological, biomimetic, and bio-inspired approaches for MEMS/NEMS and medicinal self-powered sensors. Unconventional nanomaterial sensors driven by self-sufficient energy are given a contemporary review, with a focus on the categorization of energy sources and comparisons of research involving self-powered solar, piezoresistive, triboelectric, and thermodynamic technologies. This book also focuses on the different techniques, materials, comparisons of fabrication of self-powered sensors as well as thermoelectric self-powered sensors and its implantable applications.

  • Anandamide in Health and Disease

    • 1st Edition
    • Bernard Le Foll
    • English
    Anandamide in Health and Disease, a volume in the Molecular Mediators in Health and Disease: How Cells Communicate series, is a complete reference on the roles of anandamide in health and disease states. Following the characteristics of the series, this book provides a comprehensive overview of the effects of the mediator on human health.The book is divided into two parts, the first of which provides background information on biology, regulation, synthesis and degradation and modulation of anandamide. The second part is dedicated to covering the role of anandamide in various diseases. A comprehensive panel of authors cover several somatic and psychiatric disorders, such as anxiety disorders, mood disorders, psychosis and substance use disorders. Additionally, the role of anandamide across epilepsy, Alzheimer's disease, and digestive conditions is explored.Anandamide in Health and Disease is the perfect reference for bioscience researchers seeking to understand anandamide pharmacology, biochemistry, cellular, and molecular biology. Clinicians may also be interested in better understanding the wide-ranging health effects of the mediator.

  • The Immunology of the Cat

    • 1st Edition
    • Ian R. Tizard
    • English
    The Immunology of the Cat makes available the first single-source, comprehensive review of the feline immune system, reporting on all immunologic aspects of diseases of the cat and its relatives and relating recent basic science to important clinical issues. The book opens with the evolution, domestication, and development of the cat then provides detailed information on immunity to infectious diseases, feline allergic diseases, the top feline autoimmune diseases, and feline immunodeficiencies. Content examines feline vaccines, hypersensitivity, cancer, nutrition, and the aged cat. Professionals in veterinary research and practice will appreciate complete information on all aspects of feline immunology in one essential resource.

  • Ectoparasitic Diseases

    • 1st Edition
    • James H. Diaz
    • English
    Ectoparasitic Diseases provides information on the diagnosis, treatment, and prevention of ectoparasitic conditions caused by arthropods of medical importance. The book discusses the manner in which arthropod ectoparasites threaten human health by bodily infestations, covering specific ectoparasites and the vector-borne infectious diseases transmitted by each. Chapters offer definitions, epidemiology, diagnosis, clinical manifestations, therapeutic treatments, and preventive measures. In addition, the book examines the public health, socioeconomic, and psychological impact from ectoparasitic infections.This book offers comprehensive coverage to researchers, practitioners, and advanced students studying ectoparasitic vector-borne diseases.

  • Bacterial Carbonic Anhydrases

    • 1st Edition
    • Volume 55
    • English
    Bacterial Carbonic Anhydrases, Volume 55 in The Enzymes series, highlights new advances in the field, with this new volume presenting interesting chapters on a variety of timely topics, including Overview on bacterial CA genetic families, Bacterial α-CAs, Bacterial β-CAs, Bacterial γ-CAs, Bacterial ι-CAs, Sulfonamide bacterial CA inhibitors, Non-sulfonamide bacterial CA inhibitors, Helicobacter pylori CA inhibition, Neisseria gonorrhea CA inhibition, Vancomycin resistant enterococci CA inhibition, Pseudomonas aeruginosa CA inhibition, Mycobacterium tuberculosis CA inhibition, and Challenges for developing bacterial CA inhibitors as novel antibiotics.

  • Food-borne Delivery Systems of Functional Substances for Precision Nutrition

    • 1st Edition
    • Volume 112
    • English
    Food-Borne Delivery Systems of Functional Substances for Precision Nutrition, Volume 112 highlights new advances in the field, with this new volume presenting interesting chapters on a range of topics, including Biological activity, limitations, and steady-state delivery of functional substances for precision nutrition, Nanoparticles delivery systems of functional substances for precision nutrition, Micelles delivery systems of functional substances for precision nutrition, Microgel delivery systems of functional substances for precision nutrition, Emulsions delivery systems of functional substances for precision nutrition, and Microencapsule delivery systems of functional substances for precision nutrition, and much more.Other chapters focus on Liposomes' delivery systems of functional substances for precision nutrition, Hydrogel delivery systems of functional substances for precision nutrition, Vesicle delivery systems of functional substances for precision nutrition, and Future development trend of food-borne delivery systems of functional substances for precision nutrition.

  • The Evolution of Immunotherapy Against Tumors

    An Historical Approach
    • 1st Edition
    • Domenico Ribatti
    • English
    The Evolution of Immunotherapy Against Tumors: An Historical Approach summarizes the literature concerning the development of the theory of immune surveillance against tumors. It discusses the evidence for and against this theory, along with the concept of immunoediting. Finally, current approaches in anti-tumor immunotherapy will be analyzed.The immune system plays a major role in the surveillance against tumors. To avoid attack from the immune system, tumor cells develop different strategies to escape immune surveillance. Evidence of immune surveillance comes from both animal models and clinical observations. Mice with a wide variety of immunodeficiencies have a high rate of tumor incidence and are more susceptible to transplanted or chemical carcinogen-induced tumors. Immunosuppressed patients have a high incidence of tumors. However, many patients develop cancer even in the presence of an apparently normal immune system. This indicates that tumor cells can escape immune surveillance.

  • Rowan's Primer of EEG

    • 3rd Edition
    • Lara V. Marcuse + 2 more
    • English
    **Selected for 2026 Doody's Core Titles in Neurology**Practical... brief, and easy to understand, Rowan's Primer of EEG, 3rd Edition, teaches the difficult technical aspects of how to perform and interpret EEGs. Direct, concise text, numerous illustrations and teaching points, and an extensive video library make this up-to-date reference a valuable resource for students, residents, neurologists, and epileptologists alike.

  • From Anatomy to Function of the Central Nervous System

    Clinical and Neurosurgical Applications
    • 1st Edition
    • Brandon Matteo Ascenzi
    • English
    From Anatomy to Function of the Central Nervous System: Clinical and Neurosurgical Applications features neuroradiologic images that represent today, one of the most effective resources able to detect the anatomy of the nerve structures. Simultaneously featuring neuroimages, readers can study the functional aspects of the entire central nervous system with detailed captions that describe in detail how to use and interpret them. This book includes images of the brain dissected with the Klingler’s method and white matter fiber dissection. By integrating the anatomo-functional description with the synaptic organization of the CNS, this reference is useful for anyone who wants to understand how the activity of a nerve structure arises, describing its microstructure, neurotransmitter phenotype, and neural activity. It also features descriptions of pathologic conditions which result from neuroanatomical and/or neurofunctional alterations and includes neurosurgical aspects.

  • Epigenetic Regulation of Cancer-Part C

    • 1st Edition
    • Volume 387
    • English
    Epigenetic Regulation of Cancer, Part C, Volume 389 in the International Review of Cell and Molecular Biology series, highlights new advances in the field, with this new volume presenting interesting chapters on a variety of hot topics, including Epigenetic biomarkers in breast cancer, Contribution of epigenetics to virus-driven cancer, Cancer metabolism and epigenetics, Technologies for epigenome editing, Epigenetics and cancer stemness, Epigenetic modifications in obesity-associated cancers, Epigenetics in cf microRNA in blood of solid tumors, Integrative analysis of transcriptome, chromatin accessibility, cell surface antigen in single cell level for AML, and more.Additional chapters cover Epigenetics in lung cancer, Gene Regulatory Mechanisms underlying therapy resistance in Cancer, Role of miRNAs as epigenetic regulators of immune checkpoints in cancer immunity, Epigenetic contributions to Acute myeloid leukemia (AML), Contribution of epigenetics to chemoresistance, Epigenetic contribution to the relationship between obesity and cancer, and Epigenetic regulation in ovarian cancer.

  • Linseed

    A Multipurpose-Multisector Crop of Industrial Significance
    • 1st Edition
    • Sapna Langyan + 1 more
    • English
    Linseed: A Multipurpose-Multise... Crop of Industrial Significance provides a general overview of linseed as a multipurpose-multise... crop for obtaining a number of valuable products. The book's sections present the use of linseed as food products and discuss a number of important topics, including genetic engineering and breeding advances, pre-harvest processing methods, advanced extraction and quality assessment, metabolic engineering, bioactivity, new food product development, chemistry, and functionality. The book also covers the use of linseed in the textile sector and modified linseed oil products, animal feed products, cosmetics, and personal use products, along with their industrial significance.Food waste and the challenges of linseed crop production and processing into a number of industrial products are also discussed. This book acts as a comprehensive resource for food scientists, researchers, scholars, and industrial people related to food, nutraceutical, cosmetics, pharmaceuticals, textiles, and health practitioners, especially dieticians and nutritionists.

  • Advances in Clinical Chemistry

    • 1st Edition
    • Volume 123
    • English
    Advances in Clinical Chemistry, Volume 123, the latest installment in this internationally acclaimed series, contains chapters authored by world-renowned clinical laboratory scientists, physicians, and research scientists.

  • Vesicle Trafficking in Eukaryotes

    • 1st Edition
    • Volume 93
    • English
    Current Topics in Membranes, Volume 93 highlights new advances in the field, with this new volume presenting interesting chapters on a variety of topics, including Receptor-mediated endocytosis in kidney cells during physiological and pathological conditions, Membrane transport and endocytosis in malaria parasites, Impact of Coat Protein on Evolution of Ilarviruses, and Membrane Contact Sites.

  • Imagerie des urgences neuroradiologiques

    • 1st Edition
    • François Cotton
    • French
    La survenue brutale d’un déficit neurologique oriente toujours vers la réalisation en urgence d’une imagerie du système nerveux central par scanner ou IRM. Cet examen est crucial pour la prise en charge thérapeutique du patient. Ce nouveau volume de la collection des « Syllabus de la SFR »(Société française de radiologie) et de la SFNR (Société française de neuroradiologie) propose ainsi un état de l’art de l’imagerie des urgences neuroradiologiques.C... ouvrage propose toute la sémiologie à connaître afin de pouvoir proposer la gamme diagnostique des urgences à rechercher. Il donne les clés pour privilégier la technique d’exploration la plus pertinente. Après un rappel des protocoles d’exploration en fonction des urgences, ou encore des éléments en vue de mieux comprendre la neuroradiologie interventionnelle, sont ainsi évoqués, entre autres, les accidents vasculaires cérébraux, les urgences traumatiques, infectieuses, métaboliques et toxiques, celles en fonction des régions (médullaire, orbitaire, etc.) ou en fonction des traitements sans oublier les spécificités pédiatriques, gériatriques et psychiatriques.Riche... illustré et complet, présenté de façon didactique et rédigé par les meilleurs experts en neuro-imagerie diagnostique et interventionnelle, cet ouvrage constitue la référence actuelle sur le sujet. Il est indispensable pour tous les radiologues confrontés aux urgences neuroradiologiques (vacations scanners ou IRM, permanence des soins, télémédecine) ainsi que pour les neurologues et neurochirurgiens qui prennent en charge ces patients.

  • Principles of Immunotherapy in Breast and Gastrointestinal Cancers

    Activity, Mechanisms of Resistance and New Sensitization Strategies
    • 1st Edition
    • Michele Ghidini
    • English
    Principles of Immunotherapy in Breast and Gastrointestinal Cancers: Activity, Mechanisms of Resistance, and New Sensitization Strategies presents updated research findings on immunotherapy, with a special focus on the mechanisms of resistance of those cancer types and how to overcome them.The book discusses topics such as tumor cell-intrinsic and -extrinsic mechanisms of cancer resistance to immunotherapy; the role of currently available biomarkers; strategies to overcome therapeutic resistance; sensitizing agents for cancer resistance to cell-mediated immunotherapy; and immunotherapeutic approaches, mechanisms of resistance, and sensitizing strategies in gastroesophageal and biliopancreatic tumors and colorectal cancer.It is a valuable resource for researchers, students, and members of the biomedical and medical fields who want to learn more about resistance to immunotherapy and how to overcome it.

  • Neurologic Channelopathies

    • 1st Edition
    • Volume 203
    • English
    Neurological Channelopathies, Volume 203 begins with an introductory overview highlighting common mechanistic themes that cut across different CNS and PNS presentations, but that also have potential for common treatment approaches, considering classification, genetics, and fundamental physiology of ion channels. Subsequent chapters present a detailed consideration of all genetic and immunological channelopathies. Each chapter considers Pathophysiological underpinnings - genetic or immunological; Clinical presentations; Diagnostic approach; and Treatment and management.In the last 15 years, a combination of detailed clinical, genetic, molecular electrophysiological... and immunological research has combined to result in a deep understanding of a subgroup of neurological diseases spanning the central and peripheral nervous system and which have become known collectively as the Neurological Channelopathies. Although it was originally considered that significant ion channel dysfunction would not be compatible with life, we now know this is often not the case, although severe disease can often be the result. Given these major advances, it is now the right time to combine this knowledge into a single HCN volume dedicated to the topics at hand.

  • Siderophore and Related Natural Products Biosynthesis

    • 1st Edition
    • Volume 702
    • English
    Methods in Enzymology Volume 702 highlights new advances in the field, with this new volume presenting interesting topics on Siderophore and related natural products biosynthesis

  • Neuroscience of Coffee Part B

    • 1st Edition
    • Volume 289
    • English
    Neuroscience of Coffee, Volume 289 is a pioneering volume that delves into the intricate relationship between one of the world's most beloved beverages and the human brain. Offering a comprehensive exploration of the biochemical and physiological mechanisms underlying coffee's impact on the nervous system, this groundbreaking book transcends traditional coffee literature by focusing specifically on the neurological aspects. Chapters in this new release include Coffee and Parkinson's Disease, Coffee and Alzheimer's Disease, Coffee and Multiple Sclerosis (MS), Coffee and Amyotrophic lateral sclerosis (ALS), Exploring the Complex Relationship Between Caffeine Consumption and Schizophrenia: A Review of Epidemiological and Clinical Studies, and much more.Additional chapters explore Coffee, Antioxidants, and Brain Inflammation, Behavioral and Psychological Aspects of Coffee Consumption, From Bean to Brain: Coffee, Gray Matter, and Neuroprotection in Neurological Disorders Spectrum, and Synaptic Modulation by Coffee Compounds: Insights into Neural Plasticity.

  • Environmental Challenges in Attaining Food Security

    • 1st Edition
    • Volume 9
    • English
    Environmental Challenges in Attaining Food Security, Volume Nine in the Advances in Food Security and Sustainability series, highlights new advances in the field, with this new volume presenting interesting chapter on important topics such as Exacerbation of Food Insecurity in Africa: A Consequence of the Dual Threat of COVID-19 and the Russia-Ukraine Crisis; Rising Environmental Issues: A hindrance to food security; Microplastics in Soil and Water: Unveiling Environmental Risks and Implications; Emerging Contaminants – Categorization, Effect and Treatment; The Potential Impact on Pesticides on Insect Pollinators and Their Ecological Implications, and much more.Additional chapters cover Change in geo-environmental conditions and crop productivity; Pesticide Concentration and Its Impacts: Food security Vs. Food safety; Heavy metals in soil and water: Sources, fate, toxicology and remediation; Salinity stress in Crop Plants: Effects and Eco-friendly management; Salinity Stress: Impact on Plant Growth; Micronutrient bioavailability in contaminated soil and mitigation strategies for toxicity; Decrease in Arable Land and Water; and Nano-enabled sensor modules for detection of agrochemicals in diverse soil, and water systems: Progression and future trends; Monoculture Of Crops.

  • OrthoBiologics

    • 1st Edition
    • Rachel M. Frank + 2 more
    • English
    OrthoBiologics provides state-of-the-art knowledge of current biologic therapies for a variety of orthopaedic conditions in a single source. The content is presented in a straightforward manner, including defining all currently available orthobiologic options, discussing processing characteristics and appropriate clinical use, and finally, summarizing clinical applications and outcomes as well as future potential directions.In addition to covering current approaches and applications, the editors aim for this book to present “best practices” for those practicing and researching orthopaedic pathologies and orthobiologic treatments, including blood and cellular based therapies. The editors are world-renown experts in the field and this book fills a gap in the market.

  • Microbiome and Nano-Cross-Talk

    Sustainable Agriculture and Beyond
    • 1st Edition
    • Kanchan Vishwakarma + 2 more
    • English
    Microbiome Nano-Cross-Talk: Sustainable Agriculture and Beyond presents a comprehensive overview of the functional aspects of multiphasic microbial and nanotechnological interactions within and between plants and their ecosystem. Recognizing that beneficial microbes are involved in plant growth promotion, this book highlights their mechanism and regulation to enhance plant’s yield and development even under stressed conditions. The merging of nanotechnology with microbiology is an essential aspect of this book. Various nanomaterials, their synthesis approaches as well as applications in agriculture have been studied extensively in past years.With a focus on focus the morphological, anatomical, biochemical, molecular and gene expression levels of plant growth promotion, the book is the first of its kind to enable scientists to unravel the different pathways and signaling cascades involved in response to this interaction and to understanding how nanomaterials regulate the plant-microbe associations. It critically examines the role of beneficial microbes in conjunction with nanoparticles in plants and the mechanisms adopted by the plants at the biochemical and molecular levels to enhance plant growth and mitigate various stresses.

  • Neuroscience of Coffee Part A

    • 1st Edition
    • Volume 288
    • English
    The Neuroscience of Coffee is a pioneering volume that delves into the intricate relationship between one of the world's most beloved beverages and the human brain. Offering a comprehensive exploration of the biochemical and physiological mechanisms underlying coffee's impact on the nervous system, this groundbreaking book transcends traditional coffee literature by focusing specifically on the neurological aspects. From deciphering the molecular intricacies of caffeine to examining the complex interactions within the nervous system, the volume provides an unprecedented insight into how coffee influences brain function, mental health, and neurodegenerative diseases. It addresses the growing interest in understanding everyday dietary choices and their neurological implications, filling a crucial gap in accessible yet detailed resources. This book not only contributes to the evolving field of neuroscience but also serves as a valuable guide for professionals, students, and informed laypersons seeking a deeper understanding of coffee's effects on brain health and overall well-being.

  • Comprehensive Hematology and Stem Cell Research

    • 1st Edition
    • Nima Rezaei
    • English
    **2025 PROSE Award Category Winner in Clinical Medicine**Comprehens... Hematology and Stem Cell Research is the first major reference to cover both stem cell research and therapy as well as the range of hematological disorders they are currently used to treat and may potentially be able to treat in the future. This five volume set includes fundamentals, such as the underlying mechanisms of the blood and immune system, highlighting blood disorders and cancers of the blood, including lymphoma, leukemia, and myeloma. Other sections cover stem cell research and therapy, from harvesting stem cells to their utilization in cancer treatments.Finally, the work looks to the future and explores newer stem cell research that may lead to future treatments. This book is an excellent resource for students at the graduate and post-graduate levels, academics, and researchers in the fields hematology, immunology and oncology.

  • Active Peptides for Skin Care

    • 1st Edition
    • Wenfeng Ding
    • English
    Active Peptides for Skin Care is one of the first books on the market that specifically deals with the application of peptides in the field of skin care. The book outlines the basic background to skin and peptides, describes the technical methods for transdermal administration of peptides to exert their effects, and introduces the key issue of quality control methods commonly used to ensure the effectiveness and safety of peptides.The book also covers the mechanism of action and application cases of different efficacies of skin peptides, such as: whitening and spot removal, prolonging and repairing, anti-allergy and soothing, anti-hair loss and growth, improving wrinkles, breast enlargement and slimming, acne repair, eye care, repairing stretch marks, etc.

  • Concepts and Techniques in OMICS and System Biology

    • 1st Edition
    • Asmat Farooq + 5 more
    • English
    Concepts and Techniques in OMICS and Systems Biology provides a concise and lucid account on the technical aspects of omics, system biology and their application in fields of different life science.With a strong focus on the fundamental principles understanding of metabolomics, ionomics and system biology, the book also gives an updated account on technical aspects of omics and system biology. Since both omics and systems biology fields are fast advancing filed of biological sciences, its significance and applications need to be understood from the baseline.In 10 chapters Concepts and Techniques in OMICS and Systems Biology introduces the reader to both Proteomics, Metabolomics and Ionomics, and System Biology, the technical applications, describes both the software in for proteomics as metabolomic enumeration and preludes Omics technologies and their applications.The chapters are designed in a well-defined chronology such that readers will understand the concepts and techniques involved in omics and system biology. This compilation will be ideal reading material for students, researchers and people working in the industries related to biological sciences.

  • Physico-Chemical Aspects of Dosage Forms and Biopharmaceutics

    Recent and Future Trends in Pharmaceutics, Volume 2
    • 1st Edition
    • Amit Kumar Nayak + 1 more
    • English
    Physico-Chemical Aspects of Dosage Forms and Biopharmaceutics: Recent and Future Trends in Pharmaceutics, Volume Two explores aspects of pharmaceutics with an original approach that focuses on technology, novelties and future trends. The field of pharmaceutics is highly dynamic and rapidly expanding day-by-day, so it demands a variety of amplified efforts for designing and developing pharmaceutical processes and formulation strategies. Readers will find practical information for conducting research in pharmaceutics that is ideal for researchers in academia and industry as well as advanced graduate students in pharmaceutics.In addition, the book discusses the most recent developments in biopharmaceutics, including important and exciting areas such as solubility of drugs, pharmaceutical granulation, routes of drug administration, drug absorption, bioavailability and bioequivalence.

  • Environmental Health Behavior

    Concepts, Determinants, and Impacts
    • 1st Edition
    • Ana Virgolino + 2 more
    • English
    The unique biological capacities of humankind enabled the emergence of organized societies and sophisticated and globalized cultures. The progressive and universal recognition of science and technology as bulwarks of our species' survival, longevity, and quality of life made individual and organizational behaviors the main drivers of current (and future) human and planetary health standards.Environmen... Health Behavior: Concepts, Determinants, and Impacts, integrates two different but intertwined fields, environmental health sciences and human behavior sciences, identifying and systematizing current knowledge about human behaviors and habits, and addressing the challenge of environmental sustainability. The book takes the reader through a conceptual framework for environmental health behavior (EHB) as an emerging field of public and environmental health, positioning behavior change as the main challenge for the success of promoting sustainable human and planetary health. Its reading promotes insight into the environmental impacts of human demands and behavior, and, vice-versa, about the impacts of the environment on human behavior change. Moreover, different evidence-based strategies to promote EHB change are identified as practical tools for stakeholders involved in the challenge of promoting intergenerational well-being in balanced and sustainable human-produced and natural systems.

  • Cannabis and Khat in Drug Discovery

    The Discovery Pipeline and the Endocannabinoid System
    • 1st Edition
    • Andrew G. Mtewa + 4 more
    • English
    Cannabis and Khat in Drug Discovery: The Discovery Pipeline and the Endocannabinoid System provides comprehensive coverage of two important psychoactive plants: Khat and Cannabis. Initial research has found that compounds and derivatives from Cannabis and Khat are found to have promising properties that can be used for the discovery, design and development of potential drug leads against various diseases. This book extensively discusses the drug discovery and allied sciences of these compounds in the drug discovery pipeline, including basic research and computer aided modeling in ligand-drug interactions and their interactions with the endocannabinoid system. Categorized into sections including, chemical analyses and bioassays, medicinal chemistry, chemical biology and pharmacology, clinical applications, and policy and regulations, this book covers the methods and protocols involved and will be of interest to students, researchers, policymakers and all those involved in drug discovery research.

  • Hormones and Reproduction of Vertebrates, Volume 5

    Mammals
    • 2nd Edition
    • David O. Norris + 1 more
    • English
    Hormones and Reproduction of Vertebrates, Volume 5: Mammals is the fifth of five second-edition volumes representing a comprehensive and integrated overview of hormones and reproduction in fishes, amphibians, reptiles, birds, and mammals. The book includes coverage of endocrinology, neuroendocrinology, physiology, behavior, and anatomy of mammalian reproduction. It provides a broad treatment of the roles of pituitary, thyroid, adrenal, and gonadal hormones in all aspects of reproduction, as well as descriptions of major life history events. New to this edition are chapters on the evolution of viviparity, reproduction of ungulates, carnivores, and marine mammals as well as a concluding assessment of the effect of environmental influences on mammals.The initial chapters in this book broadly examine sex determination, reproductive neuroendocrinology, stress, and hormonal regulation as they relate to male and female reproductive structure and function. Subsequent chapters introduce the evolution of viviparity and examine pregnancy in eutherian mammals, parturition, pheromones, and behavioral neuroendocrinology. The book concludes with an examination of the environmental influences on hormones and reproduction of mammals, including endocrine-disrupting chemicals and climate change.

  • Endophytic Fungi

    The Full Story of the Untapped Treasure
    • 1st Edition
    • Ahmed M. Abdel Azeem + 2 more
    • English
    Endophytic Fungi: The Full Story of the Untapped Treasure covers the developments in endophytic fungal research from beginning to the end by the eminent researchers involved in the field. It sheds light on the endophytic fungal current research, challenges, and future possibilities, the trending recent topics in the plant-fungal endophytes' biodynamics for sustainable development of bioproducts and its applications are supported in large-scale biosynthesis of industrially and pharmaceutical important biomolecules.Endophy... Fungi: The Full Story of the Untapped Treasure highlights the bioprospecting and applied aspects of endophytic fungal communities from diverse hosts and discusses the practical applications of such endophytes in detail. It also reviews recent strategies on alternative sustainable sources of medicines such as secondary metabolites of fungi instead of over collection of plants under prohibiting of biodiversity conventions. The uniqueness of this book is the inclusion of updated bioinformatics-based strategies and its importance in bioactive molecules produced by endophytic fungi. The book addresses one of the most eminent issues in this field: how to translate the potential that endophytic fungi hold in stable practical application.

  • Microbes, Microbial Metabolism and Mucosal Immunity

    An Overview
    • 1st Edition
    • Tanima Bose
    • English
    Microbes, Microbial Metabolism and Mucosal Immunity: An Overview presents a concise and well-vetted treatise on the study of microbiome and microbial metabolites. This volume is up-to-date with the most recent developments from the last decade. It encompasses the interaction of immunity and microbes — and their metabolites — from different mucosal organs including gastrointestinal system, lung, oral cavity, eye. Along with the efficiency of the immune system in inhibiting the growth and proliferation of microbes, the volume discusses how the mediators of the immune system can be targeted to develop therapies.This book presents the latest methods, gives broad and systematic coverage of most mucosal systems and diseases, and takes a fresh perspective that looks at the functional aspects of change in the microbiome. The study of microbiome and microbial metabolites and their roles in host mucosal immunology is a rapidly developing area of research. One major way in which the microbiome influences the host is through altered metabolism. Metabolites, readily available to the host, engender significant consequences. Microbial metabolites have been shown to impact the disease processes in both proximal and distal organs, including the brain in several neurocognitive disorders.

  • Fundamentals of Health Neuroscience

    • 1st Edition
    • Yi-Yuan Tang + 1 more
    • English
    Health Neuroscience is a new interdisciplinary field encompassing research from cognitive, affective, and social neuroscience, health psychology, physical and mental health, and science of behavior change. This new field addresses the longstanding gap among neuroscience, health, and behavior change within the context of health promotion.Fundamenta... of Health Neuroscience explores key topics and research, including basic principles, psychological and neural processes, brain and body interactions, and gene x brain x environment interactions. This book also covers brain-based precision prevention and intervention strategies for health decisions and promotion across the lifespan. Chapters integrate the latest research findings and explores several key topics, such as: How does the brain serve both as a predictor and an outcome of health? How can people improve self-control and achieve physical and mental health effectively? What does brain plasticity and resilience tell us about optimal learning, performance, and development throughout our life? How is the sense of meaning in life affected by dopamine and reward systems in the brain?

  • Fatty Acid-Binding Proteins and Their Roles in Human Health and Disease

    From Basic Science to Clinical Application
    • 1st Edition
    • Asim K. Duttaroy
    • English
    Fatty Acid-Binding Proteins and Their Roles in Human Health and Disease: From Basic Science to Clinical Application presents the latest information on the contributions of different FABPs in physiology and pathophysiology, along with their importance in clinical outcomes. The book is divided into six main sections that cover FABP biology and their role in inflammation and diseases, such as cardiovascular, neurological, and liver diseases, to FABPs and their clinical applications.Each chapter thoroughly reviews current literature, primary research data and clinical cases, providing readers with an overview of the latest information in the expanded field of FABPs. This is an invaluable resource for both researchers and clinicians familiar with and those new to the exciting and everchanging world of fatty acid-binding proteins and clinical disorders.

  • Food Waste Valorization

    Emerging Trends, Techno-economic and Environmental Considerations
    • 1st Edition
    • Olalere Olusegun Abayomi + 2 more
    • English
    Food Waste Valorization: Emerging Trends, Techno-economic and Environmental Considerations covers bioactive extraction, therapeutic properties and environmental concerns related to food waste conversion to value-added products, along with advanced technological breakthroughs in the field. The book also provides concepts and theories on several facets of agro-food waste valorization and its by-products, as well as opportunities and challenges. Each chapter contains viewpoints from different fields of research such as Basic Science, Agriculture, Food Science and Engineering, Chemical Engineering, Mechanical Engineering, Environmental Science, and more, with each having a unique approach to food waste valorization as it relates to their field. This is an invaluable resource for research and development professionals in post-harvest processing and renewable energy industries, as well as the academicians.

  • Advances in Clinical Chemistry

    • 1st Edition
    • Volume 122
    • English
    Advances in Clinical Chemistry, Volume 122, the latest installment in this internationally acclaimed series, contains chapters authored by world-renowned clinical laboratory scientists, physicians, and research scientists.

  • Hormones and Reproduction of Vertebrates, Volume 3

    Reptiles
    • 2nd Edition
    • David O. Norris + 1 more
    • English
    Hormones and Reproduction of Vertebrates, Volume 3: Reptiles is the third of five second-edition volumes representing a comprehensive and integrated overview of hormones and reproduction in fishes, amphibians, reptiles, birds, and mammals. The book covers endocrinology, neuroendocrinology, physiology, behavior, and anatomy of reptilian reproduction. It provides a broad treatment of the roles of pituitary, thyroid, adrenal, and gonadal hormones in all aspects of reproduction, as well as descriptions of major life history events. The initial chapters in this book broadly examine sex determination, reproductive neuroendocrinology, stress, and hormonal regulation as they relate to testicular and ovarian function. Subsequent chapters examine hormones and reproduction of specific taxa, including turtles, crocodilians, lizards, and snakes. The book concludes with an examination of environmental influences on reproduction of reptiles.

  • Neuropsychological and Psychosocial Foundations of Neuro-Oncology

    • 1st Edition
    • Herbert B. Newton + 1 more
    • English
    Neuropsychological and Psychosocial Foundations of Neuro-Oncology provides an in-depth review of common cognitive, psychological, and social manifestations that occur in patients with brain cancer and other neuro-oncological issues. Chapters discuss primary CNS tumors, brain metastases, leptomeningeal disease, paraneoplastic disorders, and many other topics. Effects of CNS and systemic cancer treatment (i.e., radiotherapy, chemotherapy, immunotherapy) are also examined, as are current practices for rehabilitation and targets for essential future interventions in vulnerable populations.This book is fully illustrated with pathology photomicrographs, CT and MRI images, tables, and molecular pathway diagrams. Bringing neuropsychological and behavioral health trial knowledge from the bench to the bedside, this volume is an essential reference for practicing neuro-oncologists, neuropsychologists, nurses, and others working in the field of neuro-oncology.

  • Hormones and Reproduction of Vertebrates, Volume 4

    Birds
    • 2nd Edition
    • David O. Norris + 1 more
    • English
    Hormones and Reproduction of Vertebrates, Volume 4: Birds is the fourth of five second-edition volumes representing a comprehensive and integrated overview of hormones and reproduction in fishes, amphibians, reptiles, birds, and mammals. The book covers endocrinology, neuroendocrinology, physiology, behavior, and anatomy of avian reproduction. It provides a broad treatment of the roles of pituitary, thyroid, adrenal, and gonadal hormones in all aspects of reproduction, as well as descriptions of major life history events. New to this edition is a concluding assessment of the effect of environmental influences on birds.The initial chapters in this book broadly examine sex determination, reproductive neuroendocrinology, stress, and hormonal regulation as they relate to male and female reproductive structure and function. Subsequent chapters examine hormones and reproduction of specific behaviors, including courtship, mating, parental care, and migration.

  • Hematopoietic Stem Cell Transplantation for Neurologic Diseases

    • 1st Edition
    • Volume 202
    • English
    Hematopoietic Stem Cell Transplantation for Neurological Diseases (HSCT), Volume 201 provides the latest information on what has been evaluated as a possible therapeutic tool in severe autoimmune diseases for the last 20 years. In the neurological field, HSCT has been widely investigated for the treatment of multiple sclerosis and evidence is accumulating about its potential use in neuromyelitis optica, stiff person syndrome, myasthenia gravis, and many immune neuropathies. Besides their strong clinical relevance, studies on HSCT in neurological diseases have contributed to new insights on the pathological mechanisms underlying CNS autoimmunity, hence this volume summarizes that research.

  • Smart Food Safety

    • 1st Edition
    • Volume 111
    • English
    Smart food safety series, highlights new advances in the field, with this new volume presenting interesting chapters. Each chapter is written by an international board of authors.

  • Mitochondrial Transplantation and Transfer

    Biology, Methods, Applications, and Disease
    • 1st Edition
    • Gokhan Burcin Kubat + 2 more
    • English
    Mitochondrial Transplantation and Transfer: Biology, Methods, Applications, and Disease, a volume in the Translational and Applied Bioenergetics series, offers a detailed overview of mitochondrial transplantation across fundamental biology, disease and early therapeutics research. Here, more than twenty experts in the field discuss transplantation and transfer of healthy mitochondria and define future steps to improve new therapeutic applications across a variety of diseases. Emphasis is placed on the physiology of mitochondrial transfer, isolation processes and their applications, transfer methods, and diagnostic and treatment use across cardiovascular, metabolic, and neurological diseases, among other disease types. Step-by-step instruction is provided around research protocols and methods discussed, along with careful attention to the ethical implications of mitochondrial transplantation research and application.

  • Update on Endocrine Disorders During Pregnancy, An Issue of Endocrinology and Metabolism Clinics of North America

    • 1st Edition
    • Volume 53-3
    • Maria Papaleontiou + 1 more
    • English
    In this issue of Endocrinology and Metabolism Clinics of North America, guest editors Drs. Rachel Pessah-Pollack and Maria Papaleontiou bring their considerable expertise to the topic of Update on Endocrine Disorders During Pregnancy. In recent years, our understanding of endocrine disorders during pregnancy has greatly evolved and changed. In this issue, top experts provide updates on transgender reproductive health, PCOS management during pregnancy, hypertension, diabetes, congenital adrenal hyperplasia during pregnancy, and more.

  • Quick Guide to Endocrinology

    The Pediatric Version
    • 2nd Edition
    • William E. Winter + 2 more
    • English
    Quick Guide to Endocrinology, The Pediatric Version, Second Edition, continues to be an essential resource which focuses on the physiology, diagnostics, and laboratory testing of endocrine (hormone-mediated) disorders encountered in the field of endocrinology with expanded coverage of pediatric endocrinology. The guide is for laboratory scientists and technicians, as well as trainees and clinicians in the field of pediatrics and pediatric endocrinology including fellows, residents, medical students, nursing students, and advance practice providers and students. It is presented in an easy to read, quick format, the physiology and method of measurement for hormones essential to many bodily processes and how their dysregulation results in disease. The characteristics of such diseases and diagnostic testing including up-to-date molecular testing is addressed.

  • Advances in Parasitology

    • 1st Edition
    • Volume 125
    • English
    Advances in Parasitology, Volume 125 provides detailed and comprehensive reviews written by experts covering all aspects of parasitology. Chapters in this new release include New directions for malaria vector control using geography and geospatial analysis, PfEMP1 – Still of key importance in Plasmodium falciparum malaria immunity and pathogenesis, and Fish Ectoparasite Detection, Collection and Curation.

  • Melatonin

    A Ubiquitous Pleiotropic Molecule
    • 1st Edition
    • Sheikh Mansoor + 3 more
    • English
    Melatonin: A Ubiquitous Pleiotropic Molecule equips researchers with an understanding of the molecular biology of melatonin in plants. The book explores the occurrence of melatonin in several plant species, covering key aspects, including its biosynthesis, physiological function in plant growth and development, and signaling pathways. It then discusses the benefits melatonin has for plant and agricultural development, as well as how it can be utilized as a therapeutic in the treatment of human diseases. The role it can play in the oxidative stress response and circadian rhythm modulation are covered, as well as its nutraceutical potential for human health.The book also covers the importance of melatonin in a range of fields, including drug discovery and disease resistance, agriculture, botany, and biotechnology, and is an ideal reference for researchers across these disciplines.

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