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Advances in Clinical Chemistry
- 1st Edition, Volume 123 - August 22, 2024
- Editor: Gregory S. Makowski
- Language: English
- Hardback ISBN:9 7 8 - 0 - 4 4 3 - 2 9 7 0 6 - 9
- eBook ISBN:9 7 8 - 0 - 4 4 3 - 2 9 7 0 7 - 6
Advances in Clinical Chemistry, Volume 123, the latest installment in this internationally acclaimed series, contains chapters authored by world-renowned clinical laboratory scient… Read more
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Request a sales quoteAdvances in Clinical Chemistry, Volume 123, the latest installment in this internationally acclaimed series, contains chapters authored by world-renowned clinical laboratory scientists, physicians, and research scientists.
- Provides the most up-to-date technologies in clinical chemistry and clinical laboratory science
- Authored by world renowned clinical laboratory scientists, physicians, and research scientists
- Presents the international benchmark for novel analytical approaches in the clinical laboratory
Clinical Laboratory Professionals, Physicians and Research Scientists
- Cover image
- Title page
- Table of Contents
- Copyright
- Contributors
- Preface
- Chapter One: New markers in chronic obstructive pulmonary disease
- Abstract
- 1 Introduction
- 2 Immune mediators of COPD pathophysiology as potential diagnostic biomarkers
- 3 Biofluids for respiratory system investigation
- 4 Relevant COPD biomarkers
- 5 Novel biomarkers
- 6 Conclusion
- Acknowledgements
- References
- Chapter Two: Neurofilaments in neurologic disease
- Abstract
- 1 Introduction
- 2 Neurofilament (NF) structure and composition
- 3 NF functions
- 4 Gene expression in development
- 5 Post-transcriptional and post-translational modifications of NFs
- 6 Evolution of NF immunoassays
- 7 Confounding factors that influence NF levels
- 8 NFs in neurologic diseases
- 9 Conclusion
- References
- Chapter Three: Cortisol in metabolic syndrome
- Abstract
- 1 Introduction
- 2 Cortisol
- 3 Metabolic syndrome (MetS)
- 4 Conclusions
- References
- Chapter Four: A spotlight on the aged pulmonary artery
- Abstract
- 1 Introduction
- 2 The imprint of age on endothelial function
- 3 Age-associated structural changes in the pulmonary vasculature
- 4 PA hemodynamics influenced by age
- 5 Atherosclerosis as a normal change with age
- 6 Additional factors shaping PA parameters
- 7 Conclusion
- References
- Chapter Five: RNA biomarkers in cancer therapeutics: The promise of personalized oncology
- Abstract
- Abbreviations
- 1 Introduction
- 2 RNA biomarkers
- 3 RNA biomarkers and detection
- 4 Predicting chemotherapeutic response
- 5 Predicting chemotherapy-induced toxicity
- 6 RNA biomarkers in radiotherapy (RT)
- 7 Estimating immunotherapy response with RNA biomarkers
- 8 Mining RNA biomarkers using Artificial Intelligence
- 9 Circulating extracellular vesicles (EVs) as RNA biomarker sources
- 10 Biomarkers in other biologic samples
- 11 Achieving personal oncology
- 12 RNA biomarkers in clinical trials and practice
- 13 Conclusions
- References
- Chapter Six: Digital biomarkers in Parkinson’s disease
- Abstract
- 1 Introduction
- 2 Digital biomarkers in Parkinson’s disease
- 3 Machine learning algorithms: too good to be true
- 4 Limitations, challenges and future perspectives
- 5 Conclusions
- References
- Index
- No. of pages: 232
- Language: English
- Edition: 1
- Volume: 123
- Published: August 22, 2024
- Imprint: Academic Press
- Hardback ISBN: 9780443297069
- eBook ISBN: 9780443297076
GM
Gregory S. Makowski
Dr Gregory S Makowski is a board-certified clinical chemist and fellow of the National Academy of Clinical Biochemistry. Following receipt of his PhD in Biochemistry from the University of Connecticut Storrs, he pursued post-doctoral studies at the University of Connecticut School of Medicine in Farmington that culminated in joint appointments in the School of Medicine and the Department of Laboratory Medicine at John Dempsey Hospital. He has numerous clinical and basic science publications and serves on various scientific and editorial boards. He is actively engaged in the training of Pathology residents and fellows in the Department of Pathology and Laboratory Medicine at Hartford Hospital. He currently serves as Vice President Clinical Laboratory Services Hartford HealthCare in Connecticut.
Affiliations and expertise
Vice President and Chief Scientific Officer, Clinical Laboratory Partners, Newington, CT, USA