Epigenetic Regulation of Cancer-Part C
- 1st Edition, Volume 387 - August 23, 2024
- Imprint: Academic Press
- Editors: Sheila Spada, Lorenzo Galluzzi
- Language: English
- Hardback ISBN:9 7 8 - 0 - 4 4 3 - 2 1 4 4 6 - 2
- eBook ISBN:9 7 8 - 0 - 4 4 3 - 2 1 5 4 7 - 6
Epigenetic Regulation of Cancer, Part C, Volume 389 in the International Review of Cell and Molecular Biology series, highlights new advances in the field, with this new volume pr… Read more
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Request a sales quoteEpigenetic Regulation of Cancer, Part C, Volume 389 in the International Review of Cell and Molecular Biology series, highlights new advances in the field, with this new volume presenting interesting chapters on a variety of hot topics, including Epigenetic biomarkers in breast cancer, Contribution of epigenetics to virus-driven cancer, Cancer metabolism and epigenetics, Technologies for epigenome editing, Epigenetics and cancer stemness, Epigenetic modifications in obesity-associated cancers, Epigenetics in cf microRNA in blood of solid tumors, Integrative analysis of transcriptome, chromatin accessibility, cell surface antigen in single cell level for AML, and more.
Additional chapters cover Epigenetics in lung cancer, Gene Regulatory Mechanisms underlying therapy resistance in Cancer, Role of miRNAs as epigenetic regulators of immune checkpoints in cancer immunity, Epigenetic contributions to Acute myeloid leukemia (AML), Contribution of epigenetics to chemoresistance, Epigenetic contribution to the relationship between obesity and cancer, and Epigenetic regulation in ovarian cancer.
Additional chapters cover Epigenetics in lung cancer, Gene Regulatory Mechanisms underlying therapy resistance in Cancer, Role of miRNAs as epigenetic regulators of immune checkpoints in cancer immunity, Epigenetic contributions to Acute myeloid leukemia (AML), Contribution of epigenetics to chemoresistance, Epigenetic contribution to the relationship between obesity and cancer, and Epigenetic regulation in ovarian cancer.
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- Cover image
- Title page
- Table of Contents
- Series Page
- Copyright
- Contributors
- Epigenetic regulation of cancer
- Acknowledgments
- References
- Chapter One: Epigenetic contribution to cancer
- Abstract
- 1 Introduction to epigenetics and cancer
- 2 Epigenetic drivers of oncogenesis
- 3 Interrogating the epigenomic alterations in malignancies
- 4 Epigenetic biomarkers: bridging the gap between diagnosis and prognosis
- 5 Conclusion: decoding the epigenome: revolutionizing oncology through diagnosis, treatment, and prevention
- References
- Chapter Two: Epigenetic alterations in AML: Deregulated functions leading to new therapeutic options
- Abstract
- 1 Introduction: epigenetic alterations in acute myeloid leukemia
- 2 Epigenetic alterations lead to differentiation impairment in AML
- 3 Epigenetic alterations lead to gain of stemness in leukemic stem cells (LSCs)
- 4 Epigenetic alterations in AML maintenance and expansion
- 5 Combinatorial epigenetic therapy in AML
- 6 Conclusion
- Acknowledgment
- References
- Chapter Three: Epigenetic regulation in ovarian cancer
- Abstract
- 1 Introduction
- 2 The roles of epigenetics on ovarian cancer development
- 3 The potential applications of epigenetics for ovarian cancer diagnosis and control
- 4 The potential applications of epigenetics for ovarian cancer therapy
- 5 Conclusion
- Funding
- References
- Chapter Four: Epigenetic orchestration of the DNA damage response: Insights into the regulatory mechanisms
- Abstract
- 1 Introduction
- 2 Modulation of DDR pathways and the epigenetic modifications during viral pathogenesis
- 3 Concluding remarks
- 4 Future perspectives
- References
- Chapter Five: Epigenetic contributions to cancer: Exploring the role of glycation reactions
- Abstract
- 1 Introduction
- 2 Effect of glycation in the epigenetics of cancer
- 3 Histone modifications in epigenetic regulation of cancer
- 4 Glycation in biological process
- 5 Intersection of glycation and epigenetics
- 6 Methodologies and techniques
- 7 Clinical implications
- 8 Limitations of current understanding
- 9 Conclusion
- Conflict of interest
- References
- Chapter Six: Epigenetic contribution to the relationship between obesity and cancer
- Abstract
- 1 Introduction
- 2 Molecular connection between obesity and cancer
- 3 Epigenetic regulation of obesity and cancer relationship
- 4 Conclusion and future direction
- Acknowledgments
- References
- Edition: 1
- Volume: 387
- Published: August 23, 2024
- Imprint: Academic Press
- No. of pages: 277
- Language: English
- Hardback ISBN: 9780443214462
- eBook ISBN: 9780443215476
SS
Sheila Spada
Sheila Spada is at Weill Cornell Medical College, NY, USA
Affiliations and expertise
Department of Radiation Oncology, Weill Cornell Medicine, New York, NY, USALG
Lorenzo Galluzzi
Lorenzo Galluzzi is Assistant Professor of Cell Biology in Radiation Oncology at the Department of Radiation Oncology of the Weill Cornell Medical College, Honorary Assistant Professor Adjunct with the Department of Dermatology of the Yale School of Medicine, Honorary Associate Professor with the Faculty of Medicine of the University of Paris, and Faculty Member with the Graduate School of Biomedical Sciences and Biotechnology of the University of Ferrara, the Graduate School of Pharmacological Sciences of the University of Padova, and the Graduate School of Network Oncology and Precision Medicine of the University of Rome “La Sapienza”. Moreover, he is Associate Director of the European Academy for Tumor Immunology and Founding Member of the European Research Institute for Integrated Cellular Pathology.
Galluzzi is best known for major experimental and conceptual contributions to the fields of cell death, autophagy, tumor metabolism and tumor immunology. He has published over 450 articles in international peer-reviewed journals and is the Editor-in-Chief of four journals:
OncoImmunology (which he co-founded in 2011), International Review of Cell and Molecular Biology, Methods in Cell biology, and Molecular and Cellular Oncology (which he co-founded in 2013). Additionally, he serves as Founding Editor for Microbial Cell and Cell Stress, and Associate Editor for Cell Death and Disease, Pharmacological Research and iScience.
Affiliations and expertise
Assistant Professor of Cell Biology in Radiation Oncology, Department of Radiation Oncology, Weill Cornell Medical College, NY, USARead Epigenetic Regulation of Cancer-Part C on ScienceDirect