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Fatty Acid-Binding Proteins and Their Roles in Human Health and Disease
From Basic Science to Clinical Application
- 1st Edition - October 1, 2024
- Author: Asim K. Duttaroy
- Language: English
- Paperback ISBN:9 7 8 - 0 - 3 2 3 - 9 5 7 0 0 - 7
- eBook ISBN:9 7 8 - 0 - 3 2 3 - 9 5 7 0 1 - 4
Fatty Acid-Binding Proteins and Their Roles in Human Health and Disease: From Basic Science to Clinical Application presents the latest information on the contributions of differ… Read more
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Request a sales quoteFatty Acid-Binding Proteins and Their Roles in Human Health and Disease: From Basic Science to Clinical Application presents the latest information on the contributions of different FABPs in physiology and pathophysiology, along with their importance in clinical outcomes. The book is divided into six main sections that cover FABP biology and their role in inflammation and diseases, such as cardiovascular, neurological, and liver diseases, to FABPs and their clinical applications.
Each chapter thoroughly reviews current literature, primary research data and clinical cases, providing readers with an overview of the latest information in the expanded field of FABPs. This is an invaluable resource for both researchers and clinicians familiar with and those new to the exciting and everchanging world of fatty acid-binding proteins and clinical disorders.
- Compiles the most recent and comprehensive findings on fatty acid-binding proteins (FABPs)
- Describes the pathophysiology of FABPs in various diseases and as therapeutic targets
- Highlights opportunities for improving diagnosis and treatment by encompassing all pathological conditions involving FABPs
Researchers, clinicians and students of life science and medicine. Graduate students of cell biology, biochemistry, lipid biochemistry, and molecular biology. Pharma industries
Section 1: Overview of FABP biology
1. Introduction to FABP family, tissue expression & ligand specificity
2. FABP expression and regulation, structure homology with other proteins
3. Structure and functions of FABPs and other similar proteins such as SCP2, and alpha-synuclein
4. FABPs in cell signaling, angiogenesis, and gene expression
5. FABPs in cardiac remodeling
6. Impacts of dietary lipids on FABPs and cell growth
7. FABP and endocannabinoid metabolism in the liver and brain
Section 2: FABPs and inflammation
8. FABPs in inflammatory diseases
9. FABPs in immune cell functions
10. Roles of FABPs in brain inflammation
11. FABP in adipose tissue inflammation
Section-3: FABPs in metabolic disorders & Obesity
12. FABPs in the development of insulin resistance and diabetes
13. FABPs in the development and progression of cardiovascular diseases
14. FABPs and metabolic syndrome
15. Role of FABPs in obesity
Section-4: FABPs and human diseases
16. FABPs dysregulation and human diseases
17. FABPs and brain diseases
18. FABPs and liver diseases
19. FABPs and developmental diseases
20. FABPs in reperfusion injury in tissues
21. FABPs in celiac diseases
Section 5: FABPs and Cancers
21. Diverse roles of FABPs in the development of cancers
22. FABPs in Prostate, bladder and kidney cancers
23. Capter-24: FABPs in psoriasis
24. FABPs and breast cancers
Section 6: FABPs in Clinical applications
25. Plasma FABPs as biomarkers of diseases
26. Clinical usefulness of urinary FABPs in assessing several diseases
27. FABPs as therapeutic targets in different diseases
1. Introduction to FABP family, tissue expression & ligand specificity
2. FABP expression and regulation, structure homology with other proteins
3. Structure and functions of FABPs and other similar proteins such as SCP2, and alpha-synuclein
4. FABPs in cell signaling, angiogenesis, and gene expression
5. FABPs in cardiac remodeling
6. Impacts of dietary lipids on FABPs and cell growth
7. FABP and endocannabinoid metabolism in the liver and brain
Section 2: FABPs and inflammation
8. FABPs in inflammatory diseases
9. FABPs in immune cell functions
10. Roles of FABPs in brain inflammation
11. FABP in adipose tissue inflammation
Section-3: FABPs in metabolic disorders & Obesity
12. FABPs in the development of insulin resistance and diabetes
13. FABPs in the development and progression of cardiovascular diseases
14. FABPs and metabolic syndrome
15. Role of FABPs in obesity
Section-4: FABPs and human diseases
16. FABPs dysregulation and human diseases
17. FABPs and brain diseases
18. FABPs and liver diseases
19. FABPs and developmental diseases
20. FABPs in reperfusion injury in tissues
21. FABPs in celiac diseases
Section 5: FABPs and Cancers
21. Diverse roles of FABPs in the development of cancers
22. FABPs in Prostate, bladder and kidney cancers
23. Capter-24: FABPs in psoriasis
24. FABPs and breast cancers
Section 6: FABPs in Clinical applications
25. Plasma FABPs as biomarkers of diseases
26. Clinical usefulness of urinary FABPs in assessing several diseases
27. FABPs as therapeutic targets in different diseases
- No. of pages: 410
- Language: English
- Edition: 1
- Published: October 1, 2024
- Imprint: Academic Press
- Paperback ISBN: 9780323957007
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Asim K. Duttaroy
Dr. Asim K. Duttaroy is a professor at the Faculty of Medicine, University of Oslo, Oslo, Norway. His research programs focus on the roles of food components on growth and development, as well as in the prevention of diseases such as diabetes and cardiovascular disease. He is also investigating the roles of the antiplatelet and antihypertensive properties of fruits and vegetables. His discoveries of antithrombotic factors in tomatoes and kiwifruits are patented internationally, and three companies (Provexis Limited in the United Kingdom, IDIA AS in Norway, and Genimen Pharmacon in India) are working to commercialize these discoveries. He has published over 265 original contributions and reviews, 6 books, and several book chapters and editorials, and he is the Editor-in-Chief of the journal Food & Nutrition Research, as well as a guest editor of several journals such as Nutrients and Frontiers in Physiology.
Affiliations and expertise
Faculty of Medicine, University of Oslo, Oslo, Norway