Neuropsychological and Psychosocial Foundations of Neuro-Oncology
- 1st Edition - August 5, 2024
- Editors: Herbert B. Newton, Ashlee R. Loughan
- Language: English
- Hardback ISBN:9 7 8 - 0 - 4 4 3 - 1 5 6 6 3 - 2
- eBook ISBN:9 7 8 - 0 - 4 4 3 - 1 5 6 6 4 - 9
Neuropsychological and Psychosocial Foundations of Neuro-Oncology provides an in-depth review of common cognitive, psychological, and social manifestations that occur in patients… Read more
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Request a sales quoteNeuropsychological and Psychosocial Foundations of Neuro-Oncology provides an in-depth review of common cognitive, psychological, and social manifestations that occur in patients with brain cancer and other neuro-oncological issues. Chapters discuss primary CNS tumors, brain metastases, leptomeningeal disease, paraneoplastic disorders, and many other topics. Effects of CNS and systemic cancer treatment (i.e., radiotherapy, chemotherapy, immunotherapy) are also examined, as are current practices for rehabilitation and targets for essential future interventions in vulnerable populations.
This book is fully illustrated with pathology photomicrographs, CT and MRI images, tables, and molecular pathway diagrams. Bringing neuropsychological and behavioral health trial knowledge from the bench to the bedside, this volume is an essential reference for practicing neuro-oncologists, neuropsychologists, nurses, and others working in the field of neuro-oncology.
- Discusses the neurocognitive implications of brain and systemic cancer treatments
- Examines the foundations of neuropsychological testing and daily life implications, including caregiver support
- Covers the psychosocial implications of brain cancer, psychotherapeutic interventions, and cognitive rehabilitation
Neuro-oncologists, neurosurgeons, neuropsychologists, nurses, other oncologists, rehabilitation specialists with an interest in neuro-oncology
- Cover image
- Title page
- Table of Contents
- Copyright
- Dedication
- Contributors
- About the editors
- Preface
- Section I: Neuropsychological foundations of neuro-oncology
- Chapter 1 History of neuro-oncology and neuropsychology
- Abstract
- Introduction
- History of neuro-oncology
- History of neuropsychology
- References
- Chapter 2 Neurocognitive functioning: From brain structures to networks
- Abstract
- Introduction
- Short historical background
- Neurocognitive domains
- A network approach
- Individual differences and variability
- Conclusion
- References
- Chapter 3 Taking a therapeutic and biopsychosocial approach to the neuropsychological interview for assessment of brain tumor survivors
- Abstract
- Introduction
- Assessment models in neuropsychology
- Informed consent as an ongoing process
- Biopsychosocial model in the neuropsychological assessment of primary brain tumor patients
- Assessment domains
- Final thoughts
- References
- Chapter 4 Neuropsychological assessment in neuro-oncology
- Abstract
- Introduction
- Foundations of objective neuropsychological assessment
- Neuropsychological assessment in neuro-oncology
- Prerequisites to neuropsychological assessment
- Neurocognitive domains and the tests that measure them
- Guidlines for objective neuropsychological assessment in neuro-oncology
- Objective neuropsychological assessment in clinical trials
- Future directions
- Conclusions
- References
- Chapter 5 Patient-reported assessment: Identifying cognitive concerns in brain tumor patients
- Abstract
- Definitions and incidence
- Subjective cognitive function
- Clinical practice implementation
- Subjective cognitive function measurement
- Association with objective neuropsychological assessments
- Implications for practice
- References
- Chapter 6 Quality of life and patient-reported outcomes in neuro-oncology clinical care and research
- Abstract
- Introduction
- Quality of life in neuro-oncology
- Quality of life measurement approaches
- Applications of PROMs in neuro-oncology
- Modern approaches to capture PROs in neuro-oncology
- Future directions for PROs in neuro-oncology
- Conclusion
- References
- Section II: Effects of neuro-oncology and systemic treatment on cognitive functioning
- Chapter 7 Imaging in neuro-oncology
- Abstract
- Introduction
- Gliomas
- Adult-type diffuse gliomas
- Pediatric-type diffuse low-grade gliomas
- Pediatric-type diffuse high-grade gliomas
- Circumscribed astrocytic gliomas
- Neuronal and glioneuronal tumors
- CNS lymphoma
- Extra-axial tumors
- Metastatic disease
- References
- Chapter 8 Pathology and treatment of primary and metastatic brain tumors
- Abstract
- Pathology and treatment of primary brain tumors
- Pathology and treatment of metastatic brain tumors
- References
- Chapter 9 Overview of systemic treatment and toxicity in cancer patients
- Abstract
- Introduction
- Primary central nervous system tumors
- Breast cancer
- Prostate cancer
- Lung cancer
- Colorectal cancer
- Cutaneous melanoma
- Non-Hodgkin lymphoma
- Leukemia
- Myeloma
- Summary
- References
- Chapter 10 Delirium and mental status changes in neuro-oncology
- Abstract
- Introduction
- Delirium due to brain lesion
- Delirium due to local treatment
- Delirium due to medication
- Delirium due to complications of disease or treatment
- Management of delirium
- References
- Chapter 11 The neuropsychological impact of surgical intervention and utility of awake craniotomies
- Abstract
- Introduction
- Tools to define neurocognition in awake craniotomy patients
- Anatomical basis of cognitive function in disease states indicating awake craniotomies
- Awake brain mapping craniotomy
- References
- Chapter 12 Neuropsychological implications of radiotherapy
- Abstract
- Introduction
- Pathophysiology
- Neurocognitive and psychologic assessment and guidelines
- Risk factors for psychosocial disorders
- Radiation dosimetry and neuropsychological consequences
- Treatment
- Neurobehavioral impairment in pediatric brain tumor survivors
- Conclusion
- References
- Chapter 13 Neuropsychological manifestations of chemotherapy
- Abstract
- CRCI—Risk factors
- CRCI—Pathogenesis
- Neurovascular features of CRCI
- Neurostructural features of CRCI
- Neuroimaging features of CRCI
- Electrophysiologic features of CRCI
- Neuropathological features of CRCI
- Psychiatric features of CRCI
- Neuropsychological assessment of CRCI
- Socioeconomic toxicity of cancer and cancer therapy
- CRCI—Treatment and prevention
- Future directions
- References
- Chapter 14 Neuropsychological issues related to immunotherapy
- Abstract
- Introduction
- Epidemiology and pathophysiology
- Encephalitis
- Aseptic meningitis
- Hypophysitis
- Other ICI-associated CNS immune-related adverse events
- CAR T-cell-mediated neurotoxicity: Immune effector cell-associated neurotoxicity syndrome (ICANS)
- Conclusion
- References
- Chapter 15 Neuropsychological aspects of blood or bone marrow transplantation
- Abstract
- The blood or marrow transplantation (BMT) procedure
- Trajectory of cognitive functioning and prevalence of cognitive impairment post-BMT
- Characterization of domain-specific cognitive deficits in BMT recipients
- Risk factors for neurocognitive impairment in BMT recipients
- Genetic biomarkers in BMT recipients
- Mechanisms of neurocognitive impairment in BMT
- Neuroimaging biomarkers in BMT
- Symptom clusters related to cognitive impairment
- Pharmacological and nonpharmacological interventions to improve neurocognitive impairment
- Summary
- References
- Chapter 16 Pediatric brain tumors: Neuropsychological late effects and academic implications
- Abstract
- The medical experience
- Neurocognitive late effects
- Academic implications
- Educational interventions after treatment for pediatric brain tumor
- Conclusion
- References
- Section III: Psychosocial foundations of neuro-oncology
- Chapter 17 Depression in neuro-oncology
- Abstract
- Definition, symptoms, and causes of depression
- Screening for depression
- Depression throughout the PBT illness trajectory
- Treating depression
- Psychosocial interventions
- Conclusion
- References
- Chapter 18 Anxiety in neuro-oncology
- Abstract
- Introduction
- Concept of anxiety
- Prevalence of anxiety symptoms in adults with BT
- Prevalence of anxiety symptoms in children with BTs
- Social and demographic factors related to increased risk of anxiety symptoms in BT patients
- Clinical factors associated with anxiety
- Treatment-related factors
- Impact of anxiety on treatment outcomes and prognoses
- Conclusions
- References
- Chapter 19 Personality and behavioral changes in neuro-oncology
- Abstract
- Introduction
- Classification of personality disorders in the general population
- Personality change in glioma patients
- References
- Chapter 20 Existential distress in neuro-oncology
- Abstract
- Defining existential distress
- Existential distress in neuro-oncology
- Interventions for existential distress
- Future directions
- References
- Chapter 21 Appetite, nutrition, and body image in neuro-oncology
- Abstract
- Body image in patients with central nervous system tumors
- Appetite changes in neuro-oncology
- Nutrition and neuro-oncology
- Recommendations for providers
- Future directions
- Summary
- References
- Chapter 22 Fatigue and sleep-related issues in neuro-oncology
- Abstract
- Fatigue and sleep disturbance in neuro-oncology
- Fatigue
- Assessment of fatigue
- Treatment of fatigue
- Sleep disturbance
- Future directions
- References
- Chapter 23 The impact of brain tumor location and treatment on sexual function: Implications for clinical practice
- Abstract
- Introduction
- Overview of brain cancer and sexuality
- Location: Impact of brain tumor (patho-anatomic) location on sexuality
- Treatment: Impact of brain tumor treatment on sexuality
- Summation
- References
- Section IV: Cognitive and psychological interventions
- Chapter 24 Evidence and clinical considerations for cognitive rehabilitation
- Abstract
- Introduction
- Clinical and sociocultural considerations for cognitive rehabilitation
- An overview and discussion of evidence for cognitive rehabilitation in the acute, early outpatient, and postacute outpatient phase
- Access to care, reimbursement, and outpatient resources
- Chapter conclusion
- References
- Chapter 25 Unpacking the psychological, cognitive, and psycho-pharmacologic burdens of neuro-oncology
- Abstract
- Introduction
- Impact of neuro-oncologic diagnoses, tumor location, and treatment on patient's psychosocial, neurocognitive, and mental wellbeing
- Unraveling the tapestry: The psychosocial burden of brain cancer
- Common psychopharmacologic interventions, mechanisms of action, contraindications, and special considerations in neuro-oncology
- References
- Chapter 26 Psychotherapeutic interventions in neuro-oncology
- Abstract
- Introduction
- Types of psychotherapeutic interventions used with benefits in cancer populations
- Psychotherapeutic needs in neuro-oncology
- The dearth of psychotherapeutic interventions in neuro-oncology
- Efficacy of psychotherapeutic interventions trialed in neuro-oncology
- Conclusion
- References
- Chapter 27 Alternative and holistic approaches to neuro-oncological healthcare
- Abstract
- Exercise
- Yoga
- Mindfulness
- Acupuncture
- Supplements and experimental drug treatments
- References
- Chapter 28 Support groups and self-help resources
- Abstract
- References
- Chapter 29 Role of social work in neuro-oncology
- Abstract
- The clinician
- The case manager
- Role on interdisciplinary medical team
- Research
- Community involvement
- References
- Chapter 30 Music therapy and art therapy: Functional neurobiology and applications in oncology
- Abstract
- Introduction
- Paleo-archeology and evolution of music and art
- Neurobiology of music and art
- Overview of music therapy
- Music therapy in medical settings
- Music therapy vs music medicine
- Mental health needs of cancer patients
- Conclusion
- Overview of art therapy
- Art therapy
- Art therapy and neuroscience_ A promising partnership
- Mental health needs of cancer patients
- Art therapy with cancer patients
- Theory and evidence to practice
- Art therapy interventions for cancer patients
- Conclusion
- References
- Chapter 31 Spirituality in neuro-oncology
- Abstract
- Spirituality in oncology
- Spirituality in the care of patients with neuro-oncologic illness
- The impact of spirituality on common symptom domains in neuro-oncologic illness
- Religiosity as a behavioral symptom
- Religiosity, spirituality, and decision-making
- The role of religion and spirituality for caregivers
- Current models of addressing and measuring spiritual and existential distress in neuro-oncology patients and caregivers
- The role of the chaplain as spiritual care specialist
- References
- Section V: Supportive and palliative care in neuro-oncology
- Chapter 32 Symptom management in neuro-oncology
- Abstract
- Introduction
- Seizures and anticonvulsant therapy
- Corticosteroids
- Novel antiangiogenic agents
- Gastric acid inhibitors
- Thromboembolic complications and anticoagulation
- Dysphagia and swallowing disorders
- Psychiatric issues
- Pain control issues
- Conclusion
- References
- Chapter 33 Physical rehabilitation in neuro-oncology
- Abstract
- Introduction
- Impairments
- Other neuro-oncologic etiologies with functional impairments
- Settings of brain cancer rehabilitation
- Rehabilitation disciplines
- Conclusion
- References
- Chapter 34 Advance care planning in neuro-oncology
- Abstract
- Introduction
- New diagnosis
- Phase II—Treatment and plateau
- Phase III—Recurrence
- Phase IV—End of life
- The role of the HCP
- Conclusion
- Useful websites
- References
- Chapter 35 Delirium and psychoses
- Abstract
- Introduction
- Psychiatric disorders
- Terminal delirium and agitation
- Clinical manifestations and diagnosis
- Causes
- Care strategies and management
- Implications for prognosis and impact on family members
- Psychoses
- Pharmacologic treatment of psychoses
- Nonpharmacologic treatment of psychoses
- References
- Chapter 36 Palliative care and hospice care in neuro-oncology
- Abstract
- Introduction
- Palliative medicine in neuro-oncology
- Hospice care in neuro-oncology
- Conclusion
- References
- Chapter 37 Ethical issues in neuro-oncology
- Abstract
- Introduction
- Discussing diagnosis and prognosis
- To treat or not to treat?
- Quality of life during and after therapy
- When is it appropriate to stop therapy?
- Should hospice care be implemented?
- Conclusion
- References
- Chapter 38 Comprehensive psychosocial resources for cancer patients: The Gathering Place—An evolving model
- Abstract
- Introduction
- History
- Venues
- Funding
- Introduction to programming
- Research
- Expanding delivery of services
- References
- Chapter 39 Legal issues in cancer and neuro-oncology
- Abstract
- Introduction
- Civil torts in cancer care
- Malpractice risk in context
- Informed consent and capacity
- Right to refuse treatment
- Considerations in criminal law
- Disability insurance
- Healthcare consumer rights and protections
- Research and innovation
- Conclusion
- References
- Section VI: Caregiving in neuro-oncology
- Chapter 40 The experience of caregivers of patients in neuro-oncology
- Abstract
- Introduction
- The experience of caregiving in neuro-oncology
- The implications and associated outcomes of caregiving
- Avenues for intervention and supportive services for caregivers
- Clinical challenges in providing care to caregivers of PwPMBT
- Gaps and challenges in neuro-oncology research
- Future directions
- References
- Chapter 41 In-home care resources in neuro-oncology
- Abstract
- Introduction
- Home health services
- Special considerations with regard to home health services
- Insurance and financial services
- Terminal care at home
- References
- Index
- No. of pages: 700
- Language: English
- Edition: 1
- Published: August 5, 2024
- Imprint: Academic Press
- Hardback ISBN: 9780443156632
- eBook ISBN: 9780443156649
HN
Herbert B. Newton
Dr. Newton is currently the Director of the Neuro-Oncology Center and CNS Oncology Program at the Advent Health Cancer Institute and Advent Health Orlando Campus. He recently retired as Professor of Neurology and Neurosurgery at the Ohio State University Medical Center and the James Cancer Hospital, and was the holder of the Esther Dardinger Endowed Chair in Neuro-Oncology. He trained in Neuro-Oncology with Drs. Jerome Posner and William Shapiro at Memorial Sloan-Kettering Cancer Center in New York, and since then had been in academic Neuro-Oncology for over 25 years. He has published more than 220 peer-reviewed articles and book chapters, and is the Chief Editor or Co-Editor of ten textbooks in the field of Neurology and Neuro-Oncology. In addition, he has been listed as a Best Doctor (Neurology) and Top Doctor for Cancer (Neuro-Oncology) for the past 18 years.
Affiliations and expertise
Advent Health Cancer Institute, FL, USAAL
Ashlee R. Loughan
Dr. Loughan is a licensed clinical neuropsychologist and Associate Professor in Neurology at Virginia Commonwealth University School of Medicine. She has developed a thriving neuropsychological and quality survival program at Massey Cancer Center, LiveNOW (Neuro-Oncology Wellness). Dr. Loughan is committed to a career in neuro-oncology and conducts practice-changing cancer prevention and control research aimed to improve patients cognitive and psychological outcomes. She has demonstrated a strong record of internal and external funding, focused on understanding and improving quality survival of those challenged by brain tumors. She has authored over 40 peer-reviewed manuscripts, 9 invited book chapters, and produced 100+ abstracts at local, national, and international academic conferences. Dr. Loughan was recently recognized as a VCU Emerging Scholar and serves on the American Brain Tumor Association Clinical Advisory Counsel. She is a clinician scientist invested in the field of neuro-oncology and psycho-oncology, especially the future of quality oncology care.
Affiliations and expertise
Associate Professor, Department of Neurology, Virginia Commonwealth University USARead Neuropsychological and Psychosocial Foundations of Neuro-Oncology on ScienceDirect