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Elsevier

Books in Life sciences

  • Pharmacology of T-Cell Therapies

    • 1st Edition
    • Volume 106
    • English
    Pharmacology of T-Cell Therapies, Volume 106 in the Advances in Pharmacology series, highlights new advances in the field, with this new volume presenting interesting chapters written by an international board of authors. Topics in this new release include Enhancing persistence of therapeutic T cells, T cell manufacturing impacts on in vivo function, Transient T cell therapies, In vivo T cell therapies, T cell subsets for therapy, Engineering T cell metabolism to enhance therapeutic efficacy, and Tracking Therapeutic T cells In Vivo contacts.

  • Lights on for the Nervous System: Exploring the Effects of Photobiomodulation - Part A

    • 1st Edition
    • Volume 189
    • English
    Lights on for the Nervous System: Exploring the Effects of Photobiomodulation: Part A, Volume 187 in the International Review of Neurobiology series, highlights new advances in understanding how light interacts with the human body and brain. This comprehensive volume presents chapters written by an international board of authors, covering the history and theory of therapeutic light use, the underlying mechanisms of light–cell interactions, and the systemic effects of light exposure. It explores cognitive enhancement, sleep regulation, and microbiome modulation, as well as the potential of light-based interventions for neurodegenerative disorders, chronic pain, traumatic brain injury, depression, and retinal diseases.Specific sections cover History of Humans Using Light, Theory of Light: Why Should It Work, Mechanisms of Light, Systemic Effects of Light, Light Application and Dosage, How Does Light Affect Brain Activity, Light Talks: The Role of Biophoton in Cellular Communication, Biophotons: Communication with Light, Light Effects on Brain Activity: Simulations/Dynamic Function, Cognitive Enhancement through Transcranial Infrared Laser Stimulation: Insights from Research, Light Effects on the Microbiome, Lights On for Sleep, Exploring the Effect of Red and Near Infrared Light on Neurodegenerative Disease, Light Effects on Parkinson's Disease: Intracranial Application, Light Effects on Parkinson's Disease: Transcranial Application, and much more.

  • Progress in Medicinal Chemistry

    • 1st Edition
    • Volume 65
    • English
    Progress in Medicinal Chemistry, Volume 65 brings together state-of-the-art reviews and critical insights from leading scientists in the field. Each volume surveys the latest advances in drug discovery and development, with a focus on practical strategies, novel modalities, and real-world case studies. From target identification and structure-based design to optimization of pharmacokinetic properties, safety assessment, and translational science, these volumes provide a comprehensive, up-to-date overview for researchers, graduate students, and professionals working in medicinal chemistry, pharmacology, and related life sciences.Chapters in this new release cover Molecular Glues and Tactics in Hit Finding through to Lead Generation in Drug Discovery – current position and future directions.

  • Advances in Insect Physiology

    • 1st Edition
    • Volume 71
    • English
    Advances in Insect Physiology, Volume 71 in this ongoing series, highlights new advances in the field, with this new volume presenting interesting chapters on a variety of timely topics, including Virus Infection and its Endocrinological Regulation in Infected Insects, Insect Orphan Genes: Drivers of Evolutionary Innovation and Emerging Tools for Pest Management, Molecular Siege and Surrender: Cuticle Degradation and Killing Tactics of Entomopathogenic Fungi against Insect Pests, Microbiome-disease dynamics in commercially mass reared insects, Physiological Impacts of Bee Viruses, and more.

  • Current Approaches to Cryo-electron Microscopy

    • 1st Edition
    • Volume 223
    • English
    Current Approaches to Cryo-electron Microscopy, Volume 223 provides a comprehensive overview of the field, tracing its evolution from early structural studies to modern pipelines powered by deep-learning algorithms for helical reconstruction. The book addresses the persistent bottleneck of sample preparation, detailing the physical challenges of fibril clumping and interfacial adsorption, alongside emerging solutions to these problems. Chapters in this new release include Advancing biological understanding of the poxvirus scaffold through breakthroughs in cryo-electron microscopy, Pursuing the physics of cryoEM image formation, AI Tools for Cryo-EM: Protein Particle Picking, Density Map Enhancement, and Atomic Model Building, and much more.Additional chapters cover Cryo-EM of Amyloid Fibrils: Advances, Challenges, and Translational Applications, Computational Approaches for Protein Complex Modeling for Intermediate Resolution Cryo-EM Maps, Calcium-sensing receptor, involved in the oral perception of the kokumi substances, Insights into the Structure and Diversity of the Bacterial Flagellum from cryo-EM studies, Overview and future potential in structural studies of bacteriophages by cryo-electron microscopy, and more.

  • Next-Generation Onco-Therapeutics

    • 1st Edition
    • Awanish Kumar + 1 more
    • English
    Next-Generation Onco-Therapeutics explores the latest advancements in cancer treatment, focusing on personalized medicine and innovative therapeutic strategies. The book serves as a comprehensive resource for understanding how emerging technologies can reshape oncological care, providing insights into effective and compassionate patient management. Content explores cutting-edge developments in cancer therapies, featuring clinical examples and case studies that illustrate the practical application of new treatment modalities. It emphasizes the importance of integrative approaches that address the diverse needs of cancer patients, ensuring that healthcare professionals are equipped with the most current information in this rapidly evolving field. This book also addresses the urgent need for updated resources in oncological therapeutics, bridging the gap between traditional practices and modern innovations. By synthesizing diverse perspectives and evidence-based insights, it empowers healthcare providers, researchers, and policymakers to enhance treatment outcomes and improve patient well-being in the era of personalized medicine.

  • Biopolymer-Based Intelligent Food Packaging

    • 1st Edition
    • Swarup Roy
    • English
    Biopolymer-Based Intelligent Food Packaging explores the transformative potential of intelligent packaging technologies that not only enhance food preservation but also actively monitor freshness and safety throughout the supply chain. The book starts with a comprehensive introduction to intelligent packaging and innovative solutions, discussing technologies such as real-time monitoring and their implications for food safety. Following chapters explore the use of biopolymers as a sustainable solution, with each chapter reviewing applications of biopolymer-based intelligent packaging across various food categories, from fresh produce to processed items, while highlighting practical applications and benefits.In addition, the book addresses the challenges associated with scaling up commercial applications and outlines future research directions aimed at improving the economic viability and environmental sustainability of intelligent packaging technologies. This book is a valuable resource to researchers and advanced students in polymer science, packaging, and food science, as well as scientists and R&D professionals interested in innovative solutions in food packaging.

  • Advances in Clinical Chemistry

    • 1st Edition
    • Volume 133
    • English
    Advances in Clinical Chemistry, Volume 133 in this ongoing series, examines physiologic and pathophysiologic biochemistry and their impacts on Clinical Chemistry testing and design. Molecular mechanisms of disease processes are highlighted in the context of traditional, current, and emerging technologies, and advances in the development of improved diagnostic and predictive biomarkers are examined, especially those targeting early and emerging diseases. Specific chapters in this new release include Drug Induced Renal Injury (DIRI) Biomarkers, Unveiling tobacco markers in exhaled breath, Advances in small extracellular vesicle analysis, Piezoelectric Sensors in Point-of-Care Testing, Mitochondrial myopathy biomarkers, and Hormonal and Metabolic Biomarkers in Long COVID.

  • Epigenetic Therapy by Phytochemicals in Lung Cancer

    Mechanisms, Therapeutic Potential, and Clinical Implications
    • 1st Edition
    • Umesh Kumar + 3 more
    • English
    Epigenetic Therapy by Phytochemicals in Lung Cancer provides a comprehensive exploration of the intersection between cancer epigenetics and phytotherapy, focusing on lung cancer. The book emphasizes the role of epigenetic alterations in cancer progression and presents phytochemicals as promising agents capable of reversing these changes, thereby offering innovative therapeutic strategies. The content examines the mechanisms by which epigenetic modifications, such as DNA methylation and histone modification, contribute to lung cancer. It details specific phytochemicals—like curcumin, resveratrol, and quercetin—and their potential to modulate these pathways, while discussing clinical applications, challenges, and future research directions. For academics, this book equips researchers and healthcare professionals with evidence-based insights into alternative cancer therapies, enhancing understanding of multi-targeted approaches. It serves as a valuable reference for teaching and further research, promoting a more inclusive perspective in cancer care and addressing disparities in treatment access and efficacy.

  • Advances in Parasitology

    • 1st Edition
    • Volume 131
    • English
    This book explores the intersection of molecular biology, genomics, and ecology to redefine our understanding of parasitic organisms and their management. Beginning with the application of -omics research in platyhelminth parasites of fish, demonstrating how genomic and proteomic data are essential for understanding host-parasite dynamics and developing novel vaccines and treatments to support sustainable aquaculture. The focus then shifts to the complex internal ecosystems of parasites, and examining how their associated microbiomes—comprisi... bacteria, fungi, and viruses—influence parasite fitness, virulence, and host interactions. Finally, the book highlights the genus Entamoeba, delving into how how next-generation and long-read sequencing technologies have revolutionized the identification of cryptic species and improved epidemiological surveillance for pathogens like E. histolytica. Together, these chapters provide a modern framework for parasitology through the lens of advanced genetic tools and ecological integration.

  • Yoga and Prevention of Type 2 Diabetes

    An Integrated Approach to Wellness
    • 1st Edition
    • S.V. Madhu
    • English
    Yoga and Prevention of Type 2 Diabetes: An Integrated Approach to Wellness is a unique reference to approaching yoga, its principles, and how its various practices contribute to overall health and wellness and to understanding the scientific evidence and impact of yoga on glycemic control, insulin sensitivity, and stress reduction. The book lays the foundation to understanding the pathophysiology, epidemiology, and risk factors associated with type 2 diabetes while exploring the physiological and biochemical pathways by which yoga influences glucose metabolism and mitigates diabetes risk factors.Collectively... the book's chapters equip readers with a thorough understanding of Type 2 diabetes and the multifaceted role of yoga in its prevention and management. By combining theoretical knowledge with practical applications, this work will empower individuals and healthcare providers to take proactive steps toward better metabolic health through yoga.

  • Advances in Microbial Physiology

    • 1st Edition
    • Volume 88
    • English
    Advances in Microbial Physiology, Volume 88 explores the latest research and developments in microbial physiology, providing a comprehensive overview on how microorganisms function, adapt, and interact with their environments. This volume brings together leading experts to discuss fundamental processes such as metabolism, growth, gene regulation, signal transduction, stress responses, and cellular differentiation in bacteria, archaea, and fungi. Chapters cover Steroids as Antibacterials, From Feeding Cell to Fruiting Body: Multidrug Transport in the Life cycle of Dictyostelium discoideum, Evolution of xenobiotic catabolism, Glycyl-radical enzymes, How anaerobes cope with oxygen, and Extracellular Electron Transfer: From Early Life to Modern Biogeochemistry and Applications.

  • Human Microbiota for Skincare

    Sustainable, Innovative, and Personalized Skincare with Skin Microbiota
    • 1st Edition
    • Nar Singh Chauhan + 2 more
    • English
    Human Microbiota for Skincare: Sustainable, Innovative, and Personalized Skin Care with Skin Microbiota explores the latest trends, innovations, and emerging research in microbiota-based skincare, positioning readers at the forefront of skincare advancements. It presents a global overview of current and future research, providing a comprehensive understanding of the skin microbiome and its potential applications in skincare. The book offers detailed insights into the interplay between the skin microbiome and human health, with chapters covering essential topics such as Personalized Skincare, Macroecological Dynamics of Skin Microbiota, Host-Microbe Interplay During Skin Diseases and Aging, Microbiome-Based Skin Care Formulations, and Ethical Regulations of Skin Therapies.This book consolidates datasets and real-life case studies, offering practical advice on incorporating microbiota-based products into daily routines and exploring future trends in microbiota-based skincare. Whether you are a scientist, researcher, or clinician, this book is an essential resource. It provides authoritative advice from experts in microbiology, dermatology, and biochemistry, facilitating multidisciplinary research and enhancing your ability to treat patients.

  • Multifunctional Nano pharmaceuticals for Biomedical Applications

    • 1st Edition
    • Sushil K. Kashaw + 3 more
    • English
    Multifunctional Nanopharmaceuticals for Biomedical Applications covers the latest advancements in multifunctional nanopharmaceuticals while also addressing the pressing need for innovative solutions for unmet medical challenges. Each chapter explores key topics such as the fundamentals of nanotechnology and drug delivery, PEGylated lipid carriers for cancer theranostics, and the latest in biomimetic nanomicells and nanorobots. With detailed discussions on design strategies, formulation techniques, and regulatory aspects, readers will gain a thorough understanding of the complexities and innovations in this dynamic field. The exploration of clinical applications and future trends also equips readers with the knowledge to navigate the evolving landscape of nanomedicine.This is an essential resource for researchers interested in the transformative potential of nanotechnology in drug delivery and disease treatment. It empowers readers to harness cutting-edge technologies for effective therapies, paving the way for a new era of personalized, precise, and potent medicine. With the rapid evolution of nanomedicine, this book serves as a crucial tool for researchers, students, healthcare professionals, and industry experts alike, bridging the gap between fundamental concepts and their real-world applications.

  • Protein Serine/Threonine Kinases in Neurodegenerative Disorders

    • 1st Edition
    • Heba Mohamed Mansour + 1 more
    • English
    Protein Serine/Threonine Kinases in Neurodegenerative Disorders discusses protein kinase inhibitors and their potential role in modulating and treating neurodegenerative diseases. The book introduces protein kinases and inhibitors and includes detailed discussions on different types of kinases, including protein kinase C (PKC), AMP-activated protein kinase (AMPK), death-associated protein kinase 1 (DAPK1), cyclin-dependent kinases (CDKs), glycogen synthase kinases (GSKs), Rho-associated protein kinase (ROCK), microtubule affinity regulating kinases (MARKs), mammalian target of rapamycin (mTOR), leucine-rich repeat kinase 2 (LRRK2), PTEN-induced kinase 1 (PINK1), and dual-specificity tyrosine phosphorylation-regu... kinase (DYRK), and their roles in neurodegenerative disease, potential inhibitors, and therapeutic mechanisms.This book features 23 chapters written by renowned experts in the field of kinases. It explores novel targets modulated by protein kinases, including noncoding RNAs (ncRNAs) and mitogen-activated protein kinases (MAPKs) activated by tyrosine receptor kinases, and their roles in neurodegeneration. It also discusses the nexus between glycogen synthase kinases (GSKs) and glucagon-like peptide-1 receptor agonists (GLP-1RAs) and their role of metabolic regulation in neurodegeneration. The modulatory effects of protein kinase B (PKB/AKT) pathways in various neurodegenerative disorders, particularly Parkinson’s disease, are also examined. This book sheds light on bioactive compounds from natural products that target kinases and explains the role of different kinases in various pathogenic pathways and mechanisms involved in neurodegeneration, including regulated cell death, autophagy, synaptic dysfunction, and neuroinflammation.

  • Biochar Applications

    Advances in Environmental Remediation and Resource Recovery
    • 1st Edition
    • Ahmad Hussaini Jagaba + 4 more
    • English
    Biochar Applications: Advances in Environmental Remediation and Resource Recovery provides a combined approach between environmental science and environmental engineering that involves the improvement of the natural environment, or the remediation, of polluted sites. In addition, it discusses bioprocess engineering, including the synthesis, modification, characterization, and management of biochar from biomass waste materials. The book includes coverage on sources, impacts, and applications of biochar that could potentially be used as catalysts to enhance environmental remediation and resource recovery processes. Examples of applied research that demonstrate the relationship between wastewater, soil, contaminated environments, remediation, resource recovery, sustainability, and circular bioeconomy are also included.The book bridges the gap between biochar applications in wastewater treatment, soil improvement, gas mitigation, and resource recovery.

  • AI-enabled Sustainable Healthcare

    Demystifying Secure Quantum Blockchain
    • 1st Edition
    • M. Nivaashini + 4 more
    • English
    AI-Enabled Sustainable Healthcare: Demystifying Secure Quantum Blockchain explores the convergence of quantum computing, blockchain technology, and artificial intelligence in the context of healthcare. In today's rapidly evolving technological landscape, traditional healthcare systems face challenges related to data security, interoperability, and the efficient utilization of patient information. The emergence of quantum computing, blockchain, and AI presents unprecedented opportunities to overcome these challenges and revolutionize healthcare delivery. This book provides a clear and accessible overview of these complex technologies and their potential applications in healthcare. By demystifying these concepts and illustrating their real-world implications, the book equips readers with the knowledge and insights needed to navigate the intersection of technology and healthcare effectively. Furthermore, as the demand for secure, transparent, and sustainable healthcare solutions continues to grow, there is an urgent need for informed discussions and innovative approaches in this field.

  • Advances in Biomedical Engineering - Part A

    • 1st Edition
    • Volume 402
    • English
    Advances in Biomedical Engineering, Part A, Volume 402 provides a comprehensive overview of the latest developments, innovations, and research in the rapidly evolving field of biomedical engineering. This book covers a broad spectrum of topics, including medical imaging, biomaterials, tissue engineering, biomechanics, bioinstrumentation, and healthcare technologies. Specific chapters include Advances in biomedical engineering, Recent advances in nanomedicine as drug delivery systems, Advances in Nano biomaterials for Biomedical Engineering, Neurodiagnostic: Advances in diagnostic tools, Advances in Ferroptosis Research and Application, Bioink-based 3D Bioprinting: Paving the Path for Regenerative Medicine, and MRI Acute/Sub-Acute Ischemic Stroke Segmentation with Deep Learning: A Comprehensive Review.

  • Intelligent Cyber-Physical Systems for Sustainable Healthcare

    • 1st Edition
    • Vandana Bajaj + 5 more
    • English
    Intelligent Cyber-Physical Systems for Sustainable Healthcare addresses the integration of emerging technologies like Virtual Reality, Smart Robotics, and Human-Computer Interaction, which are crucial for maximizing digital health's potential. The book includes case studies that highlight challenges faced by medical practitioners and industry professionals, providing valuable insights for designing sustainable iCPS solutions. Aimed at biomedical engineers, researchers, and industry professionals, it offers guidance for developing practical applications in sustainable healthcare. Additionally, shared, cross-disciplinary experiences assist engineers with less clinical expertise in enhancing healthcare applications in the intelligent digital health sector. Overall, case studies illustrate past challenges in the healthcare industry and present effective solutions to overcome them, making the book a comprehensive resource for advancing sustainable healthcare practices.

  • Public Participation and Ethics Communication in Brain Research, Innovation, and Health

    • 1st Edition
    • Volume 9
    • English
    Public Engagement and Ethical Communication in Brain Research, Innovation, and Health, Volume Nine in the Developments in Neuroethics and Bioethics series, provides a comprehensive overview of various understandings of neuroscience and (neuro)ethics communication across research, policy, and society. Specific chapters in this new release include Neurohype Across Borders: How Media Narratives Shape Public Perception of Neurotechnology in English- and Spanish-Speaking Countries, Physicians’ Resistance Towards Pandemic Public Health Policies in Romania: Navigating Misinformation, Ethical Challenges, and Responsibility in Science Communication, Foresight Scenarios as Communicative Instruments in Anticipatory Neuroethics, and much more.Additional chapters include Draw closer to me: Participatory visual storytelling to include socio-cultural perspectives in neuroethics and policymaking, Against the Narrative of the Insufficiency of Human Rights on the Neurorights Discourse, Reflective accounts from collaborative neuro-oncology research: perspectives from patient partners and researchers, Responsible conceptualization in research and innovation, Anticipating Polarization: Public Discourse and the Unpreparedness of Neuroethics Communication, Shared Responsibility for Communicating Neuroscience Research: A Case Study for Spinal Cord Injury, and much more.Featured topics include creative and participatory approaches to (neuro)ethics communication, the impact of narratives on public perception and science policy, the importance of responsible communication in neuroscience, and the dynamics between patient partners and researchers. The volume also addresses cross-cultural perspectives and focuses on comparative case studies of current emerging neuroscience research and neurotechnologies across countries.

  • Intelligent Osteogenesis

    How A.I., New Materials, and Manufacturing Technologies Are Reshaping Bone Regeneration
    • 1st Edition
    • Carlo Galli
    • English
    Intelligent Osteogenesis: How A.I., New Materials, and Manufacturing Technologies are Reshaping Bone Regeneration delves into the revolutionary intersection of technology and medicine. The book focuses on how cutting-edge advancements like artificial intelligence, nanotechnology, biotechnology, and material science significantly influence and transform bone regeneration therapies. It aims to shed light on the multifaceted nature of this field, bringing diverse elements together to reveal their collective impact. The book covers the use of A.I. to monitor advancements, the acceleration of research, and the technological influence on the application of bone regenerative techniques.Authored by experts, it serves as a definitive guide for both biomedical researchers and clinical practitioners in dentistry and orthopedics.

  • Fruit Seeds and Peels for Sustainable Biomaterials

    • 1st Edition
    • Sneh Punia Bangar + 1 more
    • English
    Fruit Seeds and Peels for Sustainable Biomaterials explores the utilization of fruit and vegetable waste in the production of bioplastics as environmentally friendly alternatives to conventional petroleum-based plastics. The book presents innovative approaches to reducing the carbon footprint of the packaging industry while advancing principles of recyclability, sustainability, and the circular economy.The chapters provide an in-depth examination of various waste valorization techniques and compile global research efforts focused on the transformation of various fruit processing by-products. These industrial wastes are rich in polysaccharides, such as cellulose, hemicellulose, and lignin, which can be further treated to synthesize nanocellulose crystals or fibers using different physicochemical and nonconventional methods.The book highlights the application of these biomaterials in packaging, offering food professionals and other stakeholders sustainable alternatives to traditional plastic polymers. It delivers comprehensive insights into the potential of fruit seeds as a renewable source of biomaterials, and presents valuable scientific information on the technologies involved in using bio-based materials for food preservation. These insights aim to reduce the use of non-biodegradable plastic packaging materials.

  • Computational Approaches to Natural Products Discovery

    • 1st Edition
    • Volume 730
    • English
    Computational Approaches to Natural Products Discovery, Volume 720 provides descriptions of the latest techniques in computational methods for the study of natural products. Techniques covered are related to genome mining, natural product biosynthesis, natural product evolution, and natural product structure. Chapters in this new release cover Prediction of natural product bioactivity from BGC sequence to guide genome mining efforts, Genome mining for resistance genes to identify bioactive natural products with ARTS, Predicting lasso peptide structure with LassoPred, Predicting lanthipeptide structure with Rosetta, Using lsaBGC to investigate BGC Evolution, and an Analysis of BGC evolution with CORASON.

  • Emerging Diagnostic Glucose Sensing Approaches

    Diabetes
    • 1st Edition
    • Abhishek Kandwal + 2 more
    • English
    Emerging Diagnostic Glucose Sensing Approaches surveys past and recent work on non-invasive blood glucose monitoring. The book highlights two complementary paths: electromagnetic-wave... sensing, using physical models and advanced sensors to measure glucose non-invasively; and physiological techniques (ECG/EEG) integrated with artificial intelligence and deep learning to infer glucose levels. It discusses how physical models, biomedical methodologies, and engineering prototyping enable accurate analysis and device development. With a focus on breakthroughs in electromagnetic sensors and non-invasive research, this volume serves as a foundational reference for biomedical researchers and engineers pursuing next-generation glucose monitoring.

  • Advances in Immunology

    • 1st Edition
    • Volume 168
    • English
    Advances in Immunology, Volume 168, the latest release in a long-established and highly respected publication, presents current developments and comprehensive reviews in immunology. Sample topics in this new release include Alarmins in mucosal tissues and how they regulate health and disease, and more.

  • Artificial Intelligence for Multi-omics Analysis Part B

    • 1st Edition
    • Volume 222
    • English
    Artificial Intelligence for Multi-omics Analysis Part B, Volume 222 in the Progress in Molecular Biology and Translational Science series, highlights recent advances, with this new volume presenting chapters on a variety of topics, including Artificial Intelligence in multi-omics analysis of small molecule drug discovery, AI in multi-omics analysis in antimicrobial resistance, Artificial Intelligence and multi-Omics Approach in Vaccine Development, Artificial Intelligence in multi-omics Analysis of heart diseases, Artificial Intelligence in multi-omics Analysis of Kidney Diseases, Artificial Intelligence in multi-omics Analysis of Gastrointestinal Diseases, AI in multi-omics analysis in Stem cell research, and AI in multi-omics analysis in cancer, and more.Additional sections cover AI in multi-omics analysis in obstructive lung diseases, AI in multi-omics analysis in neurodiseases, AI in multi-omics analysis in autoimmune diseases, AI in multi-omics analysis of liver diseases, AI in multi-omics analysis of COVID-19 patient data, and AI in multi-omics analysis of Type 2 diabetes.

  • Novel and Innovative Drug Delivery Systems to Overcome Chemoresistance in Human Malignancies

    • 1st Edition
    • Shuvomoy Banerjee + 1 more
    • English
    Novel and Innovative Drug Delivery Systems to Overcome Chemoresistance in Human Malignancies addresses the critical challenge of cancer chemoresistance, synthesizing insights from cancer biology, molecular biology, biotechnology, and nanotechnology. The book explores the complex mechanisms underlying drug resistance, including alterations in key signaling pathways and the tumor microenvironment's role in cancer cell survival. It highlights advancements in drug delivery technologies, such as nanomedicine and biomimetic strategies, which enhance drug targeting and minimize off-target effects. The integration of techniques like CRISPR-Cas9 and artificial intelligence in developing next-generation therapies is also emphasized. For an academic audience, this book serves as an essential resource to foster interdisciplinary collaboration in cancer research. It equips researchers, clinicians, and industry professionals with the knowledge needed to navigate the evolving landscape of cancer therapeutics, addressing critical challenges in drug delivery and chemoresistance to improve patient outcomes.

  • Advanced Methodologies to Study and Enhance Cellular Cytotoxicity Against Cancer

    • 1st Edition
    • Volume 207
    • English
    Advanced Methodologies to Study and Enhance Cellular Cytotoxicity Against Cancer, Volume 207 covers the latest techniques and strategies used to investigate and boost cytotoxic activity in cells targeting cancer. Chapters include An ex vivo assay to assess CAR T cell cytotoxicity in viable tumor tissues using a two-step staining protocol, New protocol to measure mitochondria polarization/functio... at the immunological synapse, Analysis of CAR-T cell–mediated cytotoxicity in solid tumor models, Investigation of the in vitro lytic capacity of CAR-T by microscopyal, Antigen-specific T cell cytotoxicity toward target tumor cells, In vitro expansion of stem-like memory T cells via D-mannose supplementation, and much more.Additional chapters explore High-throughput time-lapse imaging of B16 target cell killing by ovalbumin-specific CD8+ T cells, Evaluation of an intracellular magneto-mechanical approach for regulating dendritic cell activation, Analyzing the effect of NK cells on in-vivo models of tumor dissemination by digital pathology and flow cytometry, Super-resolution imaging of the NK cell synapse on supported lipid bilayers using MINFLUX nanoscopy, ASSESSMENT OF NK CELL CYTOTOXICITY INDUCED BY IL-15 BASED IMMUNOTHERAPY AGAINST CANCER CELLS, Combined phenotyping and functional analysis of isolated human natural killer cells using spectral flow cytometry, and much more.

  • Immunomodulators Part B

    • 1st Edition
    • Volume 152
    • English
    Immunomodulators Part B brings together a curated set of research-focused chapters that explore how the immune system is influenced by microbes, immune checkpoint molecules, genetic regulation, and emerging therapeutic strategies. It covers the role of the microbiome and microbial products in shaping immune responses relevant to gastrointestinal cancers, examines VISTA as a “double-edged” checkpoint in cancer and autoimmunity, and uses bioinformatics to uncover immune-modulatory patterns in HPV-associated head and neck squamous cell carcinoma and bladder cancer.

  • Advances in Virus Research

    • 1st Edition
    • Volume 124
    • English
    Advances in Virus Research, Volume 124 in this ongoing seriesseries, highlights new advances in the field, with this new volume presenting interesting chapters on topics such as Emerging and Reemerging Viral Threats to Pregnancy and Nomenclature for vertically transmitted plant.

  • Working Memory

    • 1st Edition
    • Christos Constantinidis
    • English
    Working Memory provides a comprehensive examination of the neural basis of working memory, defined as the cognitive ability to maintain information over short periods. This volume addresses the need for an accessible, yet thorough resource that bridges cognitive psychology and neuroscience, focusing on how neuronal activity in the cerebral cortex underpins memory processes. It is primarily designed for undergraduate and early graduate students in neuroscience, psychology, and related fields such as cognitive science and biomedical engineering. Topics covered include brain anatomy, organization, neurophysiology, and neuroimaging techniques, all contextualized within the study of working memory.

  • Nutrition e Neurotoxicology Part A

    • 1st Edition
    • Volume 15
    • English
    Nutrition and Neurotoxicity, Volume Fifteen-Part A highlights new advances in the field, with this new volume presenting interesting chapters on a variety of timely topics, including the Effect of toluene on memory: A focus on humans, experimental models and treatment approaches, Neurotoxicological Mechanisms of Ethanol, Neurobehavioral Aspects and Methodology of Solvents, Organic solvents and neurodegenerative diseases: exploring a possible link, Neurotoxicity of propylene ethers.

  • Advances in Agronomy

    • 1st Edition
    • Volume 197
    • English
    Advances in Agronomy, Volume 197, the latest release in this leading reference on agronomy, contains a variety of updates and highlights new advances in the field, each written by an international board of authors. Chapters in this new release include Distribution, characteristics and management of Andisols for agricultural production and carbon sequestration, Reducing Emissions from Fertilizers: Opportunities and Challenges, The Unintended Consequences of N: Addressing Pollution from Nitrogenous Fertilizers with Potential Remedies, and Reconciling soil health benefits with carbon sequestration value of organic carbonaceous amendments.

  • Microbial and Biochar Technology for Waste Valorization

    • 1st Edition
    • Maulin P. Shah + 2 more
    • English
    Microbial and Biochar Technology for Waste Valorization delves into the innovative integration of microbial and biochar technologies, presenting a compelling case for their combined utilization in waste reuse to aid environmental sustainability. The book opens with a discussion of current and emerging environmental issues and the need for implementing integrated microbe-biochar processes. Initial chapters explore the fundamentals of biochar, its sources, synthesis routes, characterization methods, its impact on soil, environment, and water microbiomes, and approaches to biochar production.The book then delves deeper into its role in environmental remediation, its suitability as a microbe carrier, and the combination of biochar and microbes for various applications, including microbial fuel cells, biofertilizer, biopesticide, and water treatment processes. Final sections highlight the use of machine learning and AI for predicting biochar characteristics, biochar's potential in promoting a circular economy and carbon neutrality, and future directions for biochar-microbe applications.

  • Vector-Borne Diseases

    • 1st Edition
    • Volume 58
    • English
    Vector Borne Diseases, Volume 58 in the Methods in Microbiology series, highlights new advances in the field, with this new volume presenting interesting written by an international board of authors. Chapters in this new release cover Methods for Isolation and Characterization of Arthropod Hemocytes, Tick-to-Host Transmission of B. burgdorferi: In Vitro and In Vivo Methodologies, Decoding the Zika Virus outbreak and Infection Dynamics, Visual and molecular methods for studying pathogen persistence in flea vectors, Lipidomic Analysis of Virus-infected Cells, and Implementation of the Neutropenic Thigh Infection Murine Model with Francsiella tularensis for Development of New Antibacterials.

  • Biomarkers for Cancer Screening, Diagnosis and Targeted Therapeutic Approaches

    • 1st Edition
    • Volume 170
    • English
    Biomarkers for Cancer Screening, Diagnosis and Targeted Therapeutic Approaches, Volume 170 provides an integrated overview of the current state and future directions of biomarker research in oncology. The book bridges fundamental molecular insights with clinical applications, emphasizing how biomarkers are transforming cancer detection, diagnosis, prognosis, and personalized treatment strategies. Chapters cover an Introduction to cancer biomarkers and current research, Role of Biomarkers for cancer detection, diagnosis, and treatment, Classification of Cancer Biomarkers based on treatment strategies, Predictive, Prognosis and Diagnostic Cancer Biomarker in cancer therapeutic approaches, Biomarkers for targeted therapy and treatment decision-making, and much more.Additional sections delve in to Emerging trends in cancer biomarker and their clinical effect on personalized treatment, Recent advances in detection techniques regarding predictive, prognostic and diagnostic biomarkers in solid cancers and its future challenges, Recent advances in detection techniques regarding predictive, prognostic and diagnostic biomarkers in body fluids and its future challenges, Emerging biomarkers for non-invasive cancer diagnosis and treatment, and more. The brings together recent advancements in molecular diagnostics, predictive and prognostic markers, and targeted therapeutic development across a wide range of cancer types.

  • Artificial Intelligence Interventions in Agriculture, Food and Health Sectors

    • 1st Edition
    • Narashans Alok Sagar + 4 more
    • English
    Artificial Intelligence Interventions in Agriculture, Food and Health Sectors provides an integrated connection among agriculture, food, nutrition, and health sectors, compiling the history and evolution of AI, the scope of AI in the agricultural and food sectors, AI applications in the food processing and supply chain, and the role of AI in the food safety and healthcare industry. Edited by a multidisciplinary team, this book is a unique resource covering the innovative concepts of AI in the agriculture and food sectors, while providing useful insights to students, scientists, progressive farmers, food processing, and healthcare industries about the scope of AI applications.Users will find this to be a single platform for progressive farmers, food processing researchers, and healthcare professionals who are interested in learning about the potential of AI across a broad range of sectors. The book emphasizes the significance of stakeholder collaboration across disciplines to properly utilize the strengths of AI and handle its limitations.

  • Cytokine-Based immunotherapy Part B

    • 1st Edition
    • Volume 401
    • English
    Cytokine-Based immunotherapy: Part B, Volume 401 delves into the intricate world of cytokines, the vital signaling proteins that orchestrate the immune response and their pivotal role in modulating various immune functions. From fundamental mechanisms to their therapeutic applications, this book offers a thorough examination of the latest trends and developments in leveraging cytokines for immunotherapy. Chapters cover Cytokine-based immunotherapy in pancreatic cancer, IL-33 and its pleiotropic role in cancer, Immunocytokines based on IL-12 for cancer therapy: enhancing efficacy and reducing toxicity, Cytokine network in immunosuppression and tumor development in glioblastoma, The Double-Edged Role of Interferon Gamma in Cancer Immunity, and much more.An additional section covers Engineering Interleukin-10 for Therapeutic Applications, IL-23 Blockade: A Strategy for Relieving Inflammatory Diseases. Targeting TNF-alpha examines the immunotherapeutic approach for alleviating neuropathic pain. The key role of immunomodulatory cytokines for the development of novel nk cell-based cancer therapies focuses on the importance of cytokines in developing new cancer treatments. Finally, complexities in the clinical development of TGFβ inhibitors covers the challenges in creating inhibitors for TGFβ.

  • Pesticides and Neurotoxicant Exposures

    Impacts of Neurodevelopment and Long-Term Brain Health
    • 1st Edition
    • Neha Gogia + 1 more
    • English
    Pesticides and Neurotoxicant Exposures: Impacts of Neurodevelopment and Long-Term Brain Health explores neuroscience research, revealing how chronic pesticide exposure contributes to neurodegenerative diseases and cognitive decline. This new volume synthesizes findings on the mechanisms of pesticide-induced neurotoxicity and its impact on brain health. Targeted at researchers, clinicians, and policymakers, the book explores gaps in knowledge and the urgent need for improved regulation to protect vulnerable populations. By bridging scientific insights with public health, the book aims to advance understanding and prevention of pesticide-related neurological disorders.

  • Behavioral Biometrics and Artificial Intelligence for Neurodegenerative Diseases Assessment

    • 1st Edition
    • Vincenzo Dentamaro + 2 more
    • English
    Behavioral Biometrics and Artificial Intelligence for Neurodegenerative Diseases Assessment explores cutting-edge, non-invasive techniques for the early detection of neurodegenerative diseases. The book focuses on behavioral biometrics, which analyzes patterns in a person’s actions rather than directly measurable traits. By utilizing artificial intelligence methods—like machine learning and deep neural networks—it enables the observation of subtle changes in gait, handwriting, and speech. These advanced approaches offer promise for earlier and more accurate diagnosis, potentially improving outcomes for millions affected by conditions such as Alzheimer’s and Parkinson’s diseases through timely intervention and personalized care.In addition to its core coverage, the book delves into the practical applications of wearable sensors and the use of everyday devices like smartphones and tablets in assessments. It provides comprehensive chapters on how these technologies can aid clinicians and researchers in monitoring disease progression outside traditional clinical settings.

  • Step-by-step Approach to the Radiological Evaluation of Arthritis

    • 1st Edition
    • Muthusamy Chandramohan + 1 more
    • English
    Step-by-step Approach in the Radiological Evaluation of Arthritis is a concise, practical reference source for the evaluation and interpretation of arthritis images. The book begins by briefly reviewing relevant anatomy, clinical and biochemical considerations. Subsequent chapters analyze specific arthritis indications in radiographic images using a simple, systematic approach. The book presents guidelines for when and when not to consider other advanced imaging techniques. Final chapters are devoted to troubleshooting strategies and key not-to-miss indications in rheumatic imaging. X-rays play a crucial role in the diagnosis and management of arthritis. This book’s clear and simple explanations of the subtleties and distinctions in arthritis imaging aims to improve investigative accuracy and aid healthcare professionals in monitoring disease progression and driving treatment decisions. Clinicians and radiologists in rheumatology as well as orthopedics will find certain value in integrating this must-have handbook into their daily practice.

  • Sports Medicine and the Pelvic Floor

    Science to Practice
    • 1st Edition
    • Gráinne M. Donnelly
    • English
    Sports Medicine and the Pelvic Floor: Science to Practice shines a spotlight on a critical but often overlooked aspect of female athlete health: the pelvic floor. Bringing together the expertise of international clinicians and researchers, this book highlights persistent gaps in knowledge and practice, offering valuable direction for future research. It educates professionals on how to effectively screen, treat, and rehabilitate athletes, emphasizing that pelvic floor dysfunction can profoundly impact engagement, athletic performance, and overall well-being. By addressing this traditionally taboo subject, the authors provide evidence-based insights that call for the pelvic floor to be considered as essential in sports medicine.Sections discuss practical strategies for screening and supporting athletes, managing or alleviating symptoms, and ensuring a safe return to sport, all while prioritizing long-term pelvic health. This is an indispensable resource for anyone working with female athletes, blending science and clinical experience to advance care in this vital area.

  • Viruses

    Molecular Biology, Host Interactions, and Applications to Biotechnology
    • 2nd Edition
    • Paula Tennant + 2 more
    • English
    Viruses: Molecular Biology, Host Interactions, and Applications to Biotechnology, Second Edition provides an update on recent developments and perspectives, including coverage on the history of viruses, their structure, the organization of their genomes, and strategies in replication and expression. It emphasizes their diversity and versatility, how they cause disease, and how their human, animal, and plant hosts react. Sections also explore the beneficial aspects of viruses and how they can be utilized as tools and targets for biotechnological applications. This edition will appeal to a wide audience, including academics, researchers, and students studying the molecular biology and applications of viruses.Advances in technologies and enhanced surveillance have facilitated the monitoring of virus evolution, transmission dynamics, and pathogenesis. Coupled with the experiences of the COVID-19 pandemic, we have a better understanding of the interconnectedness of human, animal, and environmental health and the impact viruses have on society and the economy. This new release updates on many critical aspects of viruses and recent research.

  • Building Resilient Water and Food Systems under Climate Change

    • 1st Edition
    • Thendiyath Roshni + 3 more
    • English
    Building Resilient Water and Food Systems Under Climate Change aims to help readers understand and implement strategies to build resilient communities that can ensure sustainable access to both food systems and water resources. The book examines the impact of climate change on food and water security and explores how communities can adapt to these challenges. It provides an in-depth analysis of climate change science, focusing on its effects on agriculture, water resources, and ecosystems. Additionally, the book showcases case studies of communities that have successfully employed resilience strategies by integrating traditional and local knowledge systems with modern techniques. Readers will find practical solutions for managing risks and building sustainable, climate-resilient systems. By combining theoretical insights with real-world examples, this comprehensive guide is designed for policymakers, researchers, and community leaders to effectively safeguard essential resources at both macro and micro levels in the face of climate change.

  • Silicon as a Sustainable Solution for Mitigating Abiotic and Biotic Stress in Plants

    • 1st Edition
    • Volume 118
    • English
    Silicon as a Sustainable Solution for Mitigating Abiotic and Biotic Stress in Plants, Volume 118 in the Advances in Botanical Research series, presents interesting chapters on a variety of topics, including Silicon in Soil and Plant, Silicon Transporters in Agronomic Crops, The Role of Silicon in Sustainable Disease Management of Monocot Plants, Silicon in the Management of Diseases in Dicot Crops, Silicon and Biocontrol Agents for Plant Growth and Control of Diseases in Rice, Silicon for the Control of Insect Herbivores in Agronomic Crops, Silicon-Driven Phenotypic Induction Enhances Physiological Tolerance to Water Deficit and Waterlogging in Agronomic Crops, and much more.Additional sections cover Silicon Nutrition for Sugarcane Production, Silicon Nutrition of Agronomic Crops, Physiological Aspects of Silicon in Plants under Stress, and Alleviation of Heavy Metal Stress in Plants by Silicon.

  • Neurological Assessment Made Easy

    A Step-by-Step Guide for Physiotherapists
    • 1st Edition
    • Vishal Verma
    • English
    Neurological Assessment Made Easy: A Step-by-Step Guide for Physiotherapists delves into the intricacies of neurological assessment, covering a wide range of topics such as sensory and motor function, reflexes, coordination, balance, and cognition. This text provides physiotherapists and clinicians with a comprehensive framework to systematically assess and evaluate the neurological status of their patients. This book provides practical strategies and tips to navigate challenges effectively, ensuring accurate and meaningful assessment results and emphasizes the importance of effective neurological assessment in guiding the development of personalized treatment plans.

  • A Quick Reference to Obstetric Anesthesia

    • 1st Edition
    • Adithya Devadas Bhat + 1 more
    • English
    A Quick Reference to Obstetric Anesthesia is a comprehensive resource on the latest in anesthetic care for the pregnant patients. It covers the newest evidence on various critical topics in obstetric anesthesia, and the inclusion of recommended perioperative protocols provides definitive references for optimal care. This book serves as an “in the moment” tool for solving challenging clinical problems, while functioning as a reference for both experienced clinicians and trainees. It also includes relevant patient management protocols, as well as numerous emerging topics that are lacking in presently available texts.A Quick Reference to Obstetric Anesthesia is meant for anyone seeking immediately accessible information to facilitate real-time care of pregnant patients. Its approachable yet comprehensive knowledge base will be appreciated by anesthesia professionals at every level.

  • Natural Gums as a Sustainable Material for Food Packaging and Preservation

    • 1st Edition
    • Haroon Elrasheid Tahir + 3 more
    • English
    Natural Gums as a Sustainable Material for Food Packaging and Preservation focuses on the characterization, functionality, mechanisms, and processing of natural gum-based packages and its application for food preservation and smart packaging. Sections cover characterization, functionality, formulation, health, and eco-innovations in natural gums followed by global research indicators of gum packages. Additional content explores the application of natural gum and gum-based techniques for the protection of foods, including an evaluation of the potential use of gum-based smart packaging for the detection of food quality and safety in addition to the consumer acceptability of gum packaging.Final content focuses on natural gum package challenges, safety, and associated legislation followed by assessing the future potential of natural gum food packages. Edited by a team of experts in natural gums and food packaging materials, this book prioritizes sustainability and biodegradability by utilizing natural gums as an eco-friendly alternative to protect and indicate the freshness of foods.

  • A Comprehensive Guide for the Novice Researcher in Clinical Trials

    • 1st Edition
    • Miltiadis Lytras + 2 more
    • English
    A Comprehensive Guide for Novice Researcher in Clinical Trials is a must-have resource for individuals embarking on the journey of clinical research. This book is tailored for beginners, offering a clear and structured introduction to the vital principles, methodologies, and skills required to design and conduct robust clinical trials. Spanning 13 chapters, it meticulously covers the entire clinical trial process, emphasizing Good Clinical Practice (GCP) standards. From foundational research concepts to advanced trial strategies, the guide empowers readers to confidently navigate the complexities of clinical trials and contribute meaningfully to the field of healthcare.In addition to its foundational content, the book addresses a variety of important topics, such as ethical considerations, regulatory compliance, and the development of trial protocols. It explores different trial designs, types of bias, and the historical evolution of clinical research. Practical sections on data management, monitoring, statistical analysis, and project management offer readers hands-on guidance for real-world application. Notably, the book includes a dedicated focus on regulatory affairs in Saudi Arabia, making it particularly valuable for health professionals in that region.

  • Lo esencial en farmacología. Cursos Crash

    • 6th Edition
    • Catrin Page
    • Spanish
    Con una fórmula que ha demostrado su éxito a lo largo de los últimos 25 años, cada volumen de la serie se ha actualizado por completo para facilitar el estudio. La serie está escrita por estudiantes de últimos cursos y recién graduados que acaban de superar sus exámenes, y toda la información ha sido cuidadosamente revisada por profesores universitarios. Este volumen de la serie se ha mejorado para satisfacer las necesidades de los estudiantes de Medicina actuales, y las de los estudiantes y profesionales de otras disciplinas sanitarias que requieran un acceso rápido a los aspectos esenciales de la farmacología. Cada capítulo guía de forma sucinta por todos los temas curriculares, integrando los aspectos clínicos con la ciencia básica relevante y evitando los detalles innecesarios o confusos. Los cuadros destacados a lo largo del texto ofrecen los apuntes, las sugerencias y los puntos clave esenciales. Se incluye una sección de autoevaluación totalmente revisada y adaptada a los últimos formatos de exámenes para comprobar los conocimientos y para ayudar en la preparación de las pruebas. Completamente revisada y actualizada, esta sexta edición ofrece un recurso accesible de aprendizaje y repaso que facilite la compresión de los principios y las aplicaciones de la farmacología en todas las áreas de la medicina y la cirugía. Comienza con un capítulo introductorio sobre los principios básicos de la farmacología. En el resto de los capítulos, se describen los efectos de los fármacos en los distintos sistemas orgánicos y se incluyen actualizaciones sobre los avances farmacológicos más recientes en medicina (p. ej., las nuevas terapias dirigidas en oncología y enfermedades inflamatorias, así como los nuevos tratamientos utilizados en el manejo de la diabetes y la insuficiencia cardíaca). La sección de autoevaluación se ha actualizado para reflejar el contenido y el estilo de varios exámenes de pre- y posgrado. Las preguntas de autoevaluación se centran en la farmacología clínica y su aplicación a casos reales de la práctica clínica.

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