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Advances in Brain Tumor Therapy

From Molecular Mechanisms to Clinical Practice

  • 1st Edition - August 1, 2026
  • Latest edition
  • Editors: Arun Kumar Singh, Rajwinder Kaur, Thakur Gurjeet Singh, Ashutosh Pareek, Niraj Kumar Jha
  • Language: English

Advances in Brain Tumor Therapy: From Molecular Mechanisms to Clinical Practice explores the evolving landscape of brain tumor treatment, addressing challenges posed by these… Read more

Description

Advances in Brain Tumor Therapy: From Molecular Mechanisms to Clinical Practice explores the evolving landscape of brain tumor treatment, addressing challenges posed by these rare yet impactful malignancies. The book highlights significant improvements in patient prognoses due to advances in targeted therapies and immunotherapies while also recognizing the limitations of current treatment options. The content examines brain tumor epidemiology, incidence, risk factors, and survival rates followed by an extensive overview of existing therapeutic approaches, including clinical trials, targeted treatments, immunotherapies, and systemic therapies. It also delves into the critical signaling pathways that drive tumor biology and implications for future strategies.

This book serves as an essential resource for healthcare professionals, clinical researchers, medical students, and scientists, bridging the gap between basic science and clinical practice. By providing insights into the latest advancements and emerging technologies, it equips readers with the knowledge necessary to navigate the complexities of brain tumor therapy and prepare for future innovations.

Key features

  • Provides an extensive examination of brain tumors, covering epidemiology, classification, pathogenesis, and current treatment modalities
  • Emphasizes innovative treatment techniques and future research opportunities, preparing readers for potential breakthroughs in brain tumor therapy and the challenges that lie ahead in the field
  • Bridges the gap between fundamental research and clinical applications by detailing the latest advancements in therapeutic approaches, including targeted therapies, immunotherapies, and personalized medicine strategies

Readership

Oncologists, neurologists, and surgeons who specialize in the treatment of brain tumors and are seeking the latest information on therapeutic advancements

Table of contents

1. Introduction to Brain Tumors

2. Molecular Pathogenesis of Brain Tumors

3. Pharmacokinetics and Pharmacodynamics in Brain Tumor Treatment

4. Conventional Chemotherapeutic Approaches for Brain Tumor Treatment

5. Targeted Molecular Therapies for Brain Tumor

6. Immunotherapy and Brain Tumors

7. Epigenetic Therapies for Brain Tumor

8. Nanotechnology and Drug Delivery Systems for Brain Tumor

9. Stem Cells in Brain Tumor Therapy

10. Harnessing Oxidative Stress: Novel Therapeutics in Pediatric Brain Cancer

11. Advanced Imaging Techniques in Brain Tumor Diagnosis and Surgery

12. Combination Therapies for Brain Therapy: Synergistic Approaches

13. Decoding MGMT: Biochemistry, Drug Resistance, and Diagnostic Innovations

14. Molecular Mechanisms of Drug Resistance in Brain Therapy

15. Personalized Medicine in Brain Tumors

16. Innovations and Obstacles in Pediatric Brain Cancer Therapy

17. Clinical Trials and Regulatory Aspects for Brain Tumor Treatment

18. Future Directions in Brain Tumor Therapy

19. Case Studies and Real-World Applications

Product details

  • Edition: 1
  • Latest edition
  • Published: August 1, 2026
  • Language: English

About the editors

AS

Arun Kumar Singh

Arun Kumar Singh completed his M.Pharm in Pharmaceutics from Galgotias University, Greater Noida, India, and currently serves as an Assistant Professor in the Department of Pharmacy at Vivekanand Global University. His research interests span nano-formulation, blockchain, IoT, machine learning, artificial intelligence, big data analytics, cancer biology, and neuroscience. He has authored one book with IOP Publishing, contributed five book chapters with River Publishers, Denmark, and published 25 review articles, including two high-impact papers in Biochimica et Biophysica Acta (BBA) – Reviews on Cancer. Additionally, he has authored and edited 55 books with renowned publishers such as Elsevier, CRC Press, Wiley, and IOP Publishing. Recognized for his innovative mindset, leadership, and strong research acumen, Mr. Singh continues to advance interdisciplinary research in pharmaceutical sciences and healthcare technology.
Affiliations and expertise
Assistant Professor at Vivekanand Global University

RK

Rajwinder Kaur

Prof. (Dr.) Rajwinder Kaur is the Assistant Dean of Pharm D (Academics) at Chitkara College of Pharmacy, Chitkara University, Punjab, India. With sixteen years of experience in teaching and research, she has held positions such as DST Women Scientist (WOS-A) at Punjab University, Chandigarh, and received prestigious fellowships like the CSIR-SRF and UGC-MRP. Dr. Kaur was awarded the "Dr. Harpal Singh Buttar and Harinder Kaur Buttar Young Scientist Award in Pharmaceutical Sciences for Rural Women" in 2013 and the Young Scientist Award "Women in Pharmaceutical Sciences" in 2023. Her research focuses on computational drug design, synthesis of fused-heterocyclic compounds, nanomedicine, and AI, particularly in inflammation, asthma, and neurological disorders. Dr. Kaur has published over 50 papers and 10 book chapters, and has edited a book. She is a senior member of the Hong Kong Chemical, Biological & Environmental Engineering Society (HKCBEES) and a life member of the Indian Pharmacy Graduate Association (IPGA).
Affiliations and expertise
Chitkara College of Pharmacy, Chitkara University, Punjab, India

TS

Thakur Gurjeet Singh

Dr. Thakur Gurjeet Singh is a pharmacology researcher with extensive graduate training in clinical and preclinical drug development. His work focuses on the neuroprotective mechanisms of pharmacological preconditioning in neurodegenerative disorders such as Alzheimer’s disease, Parkinsonism, stroke, epilepsy, and dementia. He has investigated key protective pathways involving adenosine, opioids, CGRP, calcium signaling, protein kinase-C, heat shock proteins, and MAP kinase. His research also explores novel therapeutic pathways using agents such as morphine and capsaicin, with additional expertise in mechanistic studies of substance dependence, including nicotine, alcohol, and morphine addiction. Dr. Singh’s core competencies include animal model development and validation, anesthetic and preconditioning techniques, histopathological analysis, and behavioral data evaluation. His broader interests include ALS, stem cell therapy, and movement disorders such as tardive dyskinesia.

Affiliations and expertise
Chitkara University, Punjab, India

AP

Ashutosh Pareek

Dr. Ashutosh Pareek, Professor at Banasthali Vidyapith with over 15 years of experience in pharmaceutical sciences, holds gold medals for his Master's and Bachelor's degrees in Pharmacy. Dr. Pareek specializes in neuropharmacology and innovative drug delivery systems, focusing on neurodegenerative disorders, cancer, and autoimmune diseases. His research includes developing advanced drug delivery systems for immunomodulators like naringenin. Dr. Pareek leads a research team working on these critical health issues and has published over 45 research papers and authored five technical books. He holds an international formulation patent and has received numerous awards, including the Zee National Achievers Award 2023. His work is funded by national and international agencies such as ICMR, DST-SERB, DBT, the American Association of Pharmaceutical Scientists, and the International Brain Research Organization. He serves as a Review Editor for Frontiers in Pharmacology and Frontiers in Oncology and reviews for leading journals by Elsevier, Springer, and Bentham.

Affiliations and expertise
Professor, Department of Pharmacy, Banasthali Vidyapith, Banasthali, Tonk, Rajasthan, India

NJ

Niraj Kumar Jha

Dr. Niraj Kumar Jha is an Assistant Professor of Biotechnology at Galgotias University, India, with prior research affiliations at the Centre for Research Impact & Outcome (CRIO), Chitkara University, and Sharda University. His research portfolio encompasses over 200 peer-reviewed articles and scholarly reviews, along with an edited volume published by Springer, reflecting sustained contributions to biomedical research and translational science. According to Scopus metrics, Dr. Jha’s publications have garnered more than 10,000 citations, with an H-index exceeding 50, underscoring the broad impact and visibility of his work within the global scientific community. He is an elected Member of the Royal Society of Biology (MRSB), London, and has been recognized among the World’s Top 2% Scientists in rankings compiled by Elsevier in collaboration with Stanford University. Dr. Jha actively contributes to scientific publishing and peer review as an associate editor for the Journal of Alzheimer’s Disease (IOS Press) and IET Nanobiotechnology (Wiley) and serves on the editorial boards of several international journals, including Scientific Reports. His research is centered on elucidating the molecular and cellular mechanisms underlying complex diseases such as neurodegenerative disorders, cancer, and cardiovascular pathologies. His work particularly emphasizes the modulation of key signaling pathways and explores the therapeutic potential of natural products, phytochemicals, and synthetic small molecules in disease intervention.

Affiliations and expertise
Department of Biotechnology and Bioengineering, School of Biosciences and Technology, Galgotias University, Greater Noida, Uttar Pradesh, India