Skip to main content

Advances in Brain Tumor Therapy

From Molecular Mechanisms to Clinical Practice

  • 1st Edition - October 15, 2026
  • Latest edition
  • Editors: Arun Kumar Singh, Rajwinder Kaur, Thakur Gurjeet Singh, Ashutosh Pareek, Niraj Kumar Jha
  • Language: English

Advances in Brain Tumor Therapy: From Molecular Mechanisms to Clinical Practice explores the evolving landscape of brain tumor treatment, addressing challenges posed by these… Read more

Description

Advances in Brain Tumor Therapy: From Molecular Mechanisms to Clinical Practice explores the evolving landscape of brain tumor treatment, addressing challenges posed by these rare yet impactful malignancies. The book highlights significant improvements in patient prognoses due to advances in targeted therapies and immunotherapies while also recognizing the limitations of current treatment options. The content examines brain tumor epidemiology, incidence, risk factors, and survival rates followed by an extensive overview of existing therapeutic approaches, including clinical trials, targeted treatments, immunotherapies, and systemic therapies. It also delves into the critical signaling pathways that drive tumor biology and implications for future strategies.

This book serves as an essential resource for healthcare professionals, clinical researchers, medical students, and scientists, bridging the gap between basic science and clinical practice. By providing insights into the latest advancements and emerging technologies, it equips readers with the knowledge necessary to navigate the complexities of brain tumor therapy and prepare for future innovations.

Key features

  • Provides an extensive examination of brain tumors, covering epidemiology, classification, pathogenesis, and current treatment modalities
  • Emphasizes innovative treatment techniques and future research opportunities, preparing readers for potential breakthroughs in brain tumor therapy and the challenges that lie ahead in the field
  • Bridges the gap between fundamental research and clinical applications by detailing the latest advancements in therapeutic approaches, including targeted therapies, immunotherapies, and personalized medicine strategies

Readership

Oncologists, neurologists, and surgeons who specialize in the treatment of brain tumors and are seeking the latest information on therapeutic advancements

Table of contents

  1. Introduction to brain tumors
    Bhavesh Dharmani, Iresha Malhotra, Rajwinder Kaur, Diksha Choudhary, Thakur Gurjeet Singh, Arun Kumar Singh, Manoj S. Dikkatwar
  2. Molecular pathogenesis of brain tumors
    Akhil Sharma, Aashmi Choudhary, Maneesh Mohan, Ashi Mannan, Rajwinder Kaur, Thakur Gurjeet Singh, Arun Kumar Singh, Manoj S. Dikkatwar
  3. Pharmacokinetics and pharmacodynamics in brain tumor treatment
    Farwa Malik, Hina Shabir, Shazia Perveen, Sumaira Kanwal
  4. Conventional chemotherapeutic approaches for brain tumor treatment
    Mohini Rawat, Mani Sharma, Rama Satya Sri Kotipalli, Nemala Siva Kumar, Jyoti Sharma, Prasanth Thumpati, Ajay Singh Bisht
  5. Immunotherapy and brain tumors
    Abraham Olufemi Asuku, Ayobami Grace Fajemidagba, Oluremi Racheal Adeyemo
  6. Epigenetic therapies for brain tumor
    Anchal Chhabra, Veerta Sharma, Rajwinder Kaur, Thakur Gurjeet Singh
  7. Nanotechnology and drug delivery systems for brain tumor
    Abraham Olufemi Asuku, Ayodeji Johnson Ajibare, Hidaayah Oluwamayowa Abdulghaffaar
  8. Harnessing oxidative stress: Novel therapeutics in pediatric brain cancer
    Akrit Verma, Sanjeev Kumar Sahu
  9. Advanced imaging techniques in brain tumor diagnosis and surgery
    Ayesha Gulzar, Nimra, Shazia Perveen, Sumaira Kanwal
  10. Combination therapies for brain therapy: Synergistic approaches
    Vanshita, Thakur Gurjeet Singh, Ankit Awasthi, Chander Parkash, Sonia Dhiman
  11. Decoding MGMT: Biochemistry, drug resistance, and diagnostic innovations
    Vineeta Rohilla, Heena Khan, Rajwinder Kaur, Thakur Gurjeet Singh, Arun Kumar Singh, Manoj S. Dikkatwar
  12. Molecular mechanisms of drug resistance in brain therapy
    Gaurav Mude, Mohammad Tauqeer Sheikh, Surbhi Bhope, Sanjay Nagdev, Shilpa Borkar
  13. Personalized medicine in brain tumors
    Sweta Ravindra Singh, Ankit Awasthi, Chander Parkash, Thakur Gurjeet Singh, Sonia Dhiman
  14. Innovations and obstacles in pediatric brain cancer therapy
    Divya Kanwar, Vaidehi Tripathi, Rhythm Sharma, Supreet Kaur, Shushank Mahajan, Sanjana Mehta, Samrat Chauhan, Sanchit Dhankar, Thakur Gurjeet Singh
  15. Clinical trials and regulatory aspects for brain tumor treatment
    Khushi Garg, Somnath Das, Garima, Rajan Swami, Gurpreet Kaur, Sachin Kumar Singh, Neeraj Mittal
  16. Future directions in Brain Tumor Therapy
    Prottay Dutta, Somdutt Mujwar
  17. Case studies and real-world applications
    Bhavesh Dharmani, Yash, Preetpal Singh, Rajwinder Kaur, Thakur Gurjeet Singh, Arun Kumar Singh, Manoj S. Dikkatwar

Product details

  • Edition: 1
  • Latest edition
  • Published: October 22, 2026
  • Language: English

About the editors

AS

Arun Kumar Singh

Arun Kumar Singh is Assistant Professor in the Department of Pharmacy at the University School of Pharmaceutical Sciences, Rayat Bahra University, Sahauran, India. His research interests include nano-formulation, cancer biology, and neuroscience, alongside digital and computational approaches such as machine learning, artificial intelligence, big data analytics, blockchain, and the Internet of Things. He has contributed academic books, book chapters, and review articles in pharmaceutical sciences and healthcare technology, with a focus on interdisciplinary approaches that integrate pharmaceutical research with emerging digital technologies.

Affiliations and expertise
Assistant Professor, University School of Pharmaceutical Sciences, Rayat Bahra University V.P.O. Sahauran, Tehsil Kharar, Distt. Mohali, Punjab, India

RK

Rajwinder Kaur

Rajwinder Kaur is Assistant Dean of Pharm D (Academics) at Chitkara College of Pharmacy, Chitkara University, Punjab, India. She has extensive experience in teaching and research and has held academic and research positions, including appointment as a DST Women Scientist at Panjab University, Chandigarh. Her research focuses on computational drug design, fused heterocyclic compounds, nanomedicine, and the application of artificial intelligence in pharmaceutical research, with particular interests in inflammation, asthma, and neurological disorders. Dr. Kaur has contributed extensively to the scientific literature through scholarly publications, book chapters, and editorial work. She is actively involved in academic and research initiatives that promote innovation in pharmaceutical sciences and interdisciplinary drug discovery. She is a Senior Member of the Hong Kong Chemical, Biological & Environmental Engineering Society (HKCBEES) and a Life Member of the Indian Pharmacy Graduate Association (IPGA).
Affiliations and expertise
Chitkara College of Pharmacy, Chitkara University, Punjab, India

TS

Thakur Gurjeet Singh

Dr. Thakur Gurjeet Singh is a pharmacology researcher with extensive graduate training in clinical and preclinical drug development. His work focuses on the neuroprotective mechanisms of pharmacological preconditioning in neurodegenerative disorders such as Alzheimer’s disease, Parkinsonism, stroke, epilepsy, and dementia. He has investigated key protective pathways involving adenosine, opioids, CGRP, calcium signaling, protein kinase-C, heat shock proteins, and MAP kinase. His research also explores novel therapeutic pathways using agents such as morphine and capsaicin, with additional expertise in mechanistic studies of substance dependence, including nicotine, alcohol, and morphine addiction. Dr. Singh’s core competencies include animal model development and validation, anesthetic and preconditioning techniques, histopathological analysis, and behavioral data evaluation. His broader interests include ALS, stem cell therapy, and movement disorders such as tardive dyskinesia.

Affiliations and expertise
Chitkara University, Punjab, India

AP

Ashutosh Pareek

Ashutosh Pareek is Professor at Banasthali Vidyapith, India, with expertise in neuropharmacology and advanced drug delivery systems. His research focuses on therapeutic strategies for neurodegenerative disorders, cancer, autoimmune diseases, and related health conditions, with particular interest in the development of innovative drug delivery approaches for bioactive and immunomodulatory compounds. Dr. Pareek leads research initiatives in these areas and collaborates with national and international funding agencies on projects that advance pharmaceutical science and translational research. He has contributed extensively to the scientific literature through scholarly publications, books, patents, and research mentorship. In addition, he serves on editorial and peer-review activities for international journals in pharmacology and oncology, supporting the dissemination and evaluation of research across the biomedical sciences.

Affiliations and expertise
Professor, Department of Pharmacy, Banasthali Vidyapith, Banasthali, Tonk, Rajasthan, India

NJ

Niraj Kumar Jha

Dr. Niraj Kumar Jha is an Assistant Professor of Biotechnology at Galgotias University, India, with prior research affiliations at the Centre for Research Impact & Outcome (CRIO), Chitkara University, and Sharda University. His research portfolio encompasses over 200 peer-reviewed articles and scholarly reviews, along with an edited volume published by Springer, reflecting sustained contributions to biomedical research and translational science. According to Scopus metrics, Dr. Jha’s publications have garnered more than 10,000 citations, with an H-index exceeding 50, underscoring the broad impact and visibility of his work within the global scientific community. He is an elected Member of the Royal Society of Biology (MRSB), London, and has been recognized among the World’s Top 2% Scientists in rankings compiled by Elsevier in collaboration with Stanford University. Dr. Jha actively contributes to scientific publishing and peer review as an associate editor for the Journal of Alzheimer’s Disease (IOS Press) and IET Nanobiotechnology (Wiley) and serves on the editorial boards of several international journals, including Scientific Reports. His research is centered on elucidating the molecular and cellular mechanisms underlying complex diseases such as neurodegenerative disorders, cancer, and cardiovascular pathologies. His work particularly emphasizes the modulation of key signaling pathways and explores the therapeutic potential of natural products, phytochemicals, and synthetic small molecules in disease intervention.

Affiliations and expertise
Department of Biotechnology and Bioengineering, School of Biosciences and Technology, Galgotias University, Greater Noida, Uttar Pradesh, India

View book on ScienceDirect

Read Advances in Brain Tumor Therapy on ScienceDirect