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Elsevier

Books in Life sciences

  • Advances in Cancer Research

    • 1st Edition
    • Volume 144
    • English
    Advances in Cancer Research, Volume 144, the latest release in this ongoing, well-regarded serial, provides invaluable information on the exciting and fast-moving field of cancer research. Chapters in this new release include Gene-Environment-Mic... Interactions in Melanomagenesis, PP2A and the Cell Cycle, Current Progress Defining Calcium Signals as Therapeutic Targets in Cancer Cells, and much more.

  • Compulsive Eating Behavior and Food Addiction

    Emerging Pathological Constructs
    • 1st Edition
    • Pietro Cottone + 3 more
    • English
    Compulsive Eating Behavior and Food Addiction: Emerging Pathological Constructs is the first book of its kind to emphasize food addiction as an addictive disorder. This book focuses on the preclinical aspects of food addiction research, shifting the focus towards a more complex behavioral expression of pathological feeding and combining it with current research on neurobiological substrates. This book will become an invaluable reference for researchers in food addiction and compulsive eating constructs. Compulsive eating behavior is a pathological form of feeding that phenotypically and neurobiologically resembles the compulsive-like behaviors associated with both drug abuse and behavioral addictions. Compulsive eating behavior, including Binge Eating Disorder (BED), certain forms of obesity, and ‘food addiction’ affect an estimated 70 million individuals worldwide.

  • Advances in Food and Nutrition Research

    • 1st Edition
    • Volume 89
    • Fidel Toldra
    • English
    Advances in Food and Nutrition Research provides updated knowledge about nutrients in foods and how to avoid their deficiency, especially for those essential nutrients that should be present in the diet to reduce disease risk and optimise health. The series provides the latest advances on the identification and characterisation of emerging bioactive compounds with putative health benefits, as well as up-to-date information on food science, including raw materials, production, processing, distribution and consumption, always having in mind its nutritional benefits and health effects.

  • Bacteriology Methods for the Study of Infectious Diseases

    • 1st Edition
    • Rowena Jenkins + 1 more
    • English
    Bacteriology Methods for the Study of Infectious Diseases provides knowledge, understanding and experience of contemporary, robust methodologies for studies into the pathogenicity and virulence of human/animal bacterial pathogens. This book presents contemporary, yet widely utilized methodologies, for the study of pathogenicity and virulence in bacterial pathogens of human and/or animal origin. Protocols are clearly outlined, with lists of required equipment and reagents, alongside underpinning theory. This text will provide undergraduate and postgraduate students with practical guidance for dissertation projects with protocols for individual project ideas that can be developed further, hence a starting point for additional literature searches is also provided.

  • New Therapeutic Strategies for Brain Edema and Cell Injury

    • 1st Edition
    • Volume 146
    • English
    New Therapeutic Strategies for Brain Edema and Cell Injury, Volume 145, the latest release in the International Review of Neurobiology series, highlights new advances in the field, with this volume presenting interesting chapters on the Blood-brain barrier breakdown and brain edema formation in Alzheimer’s disease, Blast brain Injury induced edema formation and therapeutic measures, Brain edema in Parkinson’s disease. Novel therapeutic strategies, Brain edema and blood-brain barrier breakdown in sleep deprivation. Therapeutic potential of cerebrolysin, Differential cell injury induced by NMDA antagonist MK 801 in early age, Anesthetics influence Brain edema in concussive head injury, and more.

  • Natural Polysaccharides in Drug Delivery and Biomedical Applications

    • 1st Edition
    • Md Saquib Hasnain + 1 more
    • English
    Natural Polysaccharides in Drug Delivery and Biomedical Applications provides a fundamental overview of natural polysaccharides, their sources, extraction methodologies, and characterizations. It covers specific natural polysaccharides and their effective application in drug delivery and biomedical use. Additionally, chapters in the book discuss key topics including the sources and extraction methodologies of natural polysaccharides, their role in tissue engineering applications, polysaccharide-based nanoparticles in biomedical applications, and their role in the delivery of anticancer drugs. Written by industry leaders and edited by experts, this book emphasizes recent advances made in the field.Natural Polysaccharides in Drug Delivery and Biomedical Applications provides academics, researchers, and pharmaceutical health care professionals with a comprehensive book on polysaccharides in pharmaceutical delivery process.

  • Nutritional Epigenomics

    • 1st Edition
    • Volume 14
    • English
    Nutritional Epigenomics offers a comprehensive overview of nutritional epigenomics as a mode of study, along with nutrition’s role in the epigenomic regulation of disease, health and developmental processes. Here, an expert team of international contributors introduces readers to nutritional epigenomic regulators of gene expression, our diet’s role in epigenomic regulation of disease and disease inheritance, caloric restriction and exercise as they relate to recent epigenomic findings, and the influence of nutritional epigenomics over circadian rhythms, aging and longevity, and fetal health and development, among other processes. Disease specific chapters address metabolic disease (obesity and diabetes), cancer, and neurodegeneration, among other disorders. Diet-gut microbiome interactions in the epigenomic regulation of disease are also discussed, as is the role of micronutrients and milk miRNAs in epigenetic regulation. Finally, chapter authors examine ongoing discussions of race and ethnicity in the social-epigenomic regulation of health and disease.

  • Accurate Results in the Clinical Laboratory

    A Guide to Error Detection and Correction
    • 2nd Edition
    • Amitava Dasgupta + 1 more
    • English
    Accurate Results in the Clinical Laboratory: A Guide to Error Detection and Correction, Second Edition, provides a comprehensive review of the factors leading to errors in all areas of clinical laboratory testing. This trusted guide addresses interference issues in all laboratory tests, including patient epigenetics, processes of specimen collection, enzymes and biomarkers. Clinicians and laboratory scientists will both benefit from this reference that applies discussions to both accurate specimen analysis and optimal patient care. Hence, this is the perfect reference for clinical laboratorians, from trainees, to experienced pathologists and directors.

  • Basics of Chimeric Antigen Receptor (CAR) Immunotherapy

    • 1st Edition
    • Mumtaz Y. Balkhi
    • English
    Basics of Chimeric Antigen Receptor (CAR) Immunotherapy presents the latest on how T cell adoptive immunotherapy has progressed in its ultimate goal of curing metastatic malignant cancers. Recent clinical data obtained with checkpoint receptor blockade inhibitors and chimeric antigen receptor (CAR) therapy has been especially promising, thus generating renewed hope that we may be on the verge of finally curing cancer. Over the years, huge progress has been made in controlling several stage IV metastasized cancers through the clinical application of checkpoint receptor inhibitory drugs and CAR-Therapy that has seen unprecedented interest in the immunotherapy field.

  • The Role of Alternative and Innovative Food Ingredients and Products in Consumer Wellness

    • 1st Edition
    • Charis M. Galanakis
    • English
    The Role of Alternative and Innovative Food Ingredients and Products in Consumer Wellness provides a guide for innovative food ingredients and food products. The book covers consumer wellness as it relates to food ingredients and functional foods, alternative ingredients, food products fortified with extracts derived from food processing by-products, food products based on Omega-3 polyunsaturated fatty acids and their health effects, selected superfoods and related super diets, edible insects, microalgae as health ingredients for functional foods and spirulina related products, fruit-based functional foods, pro- and pre-biotics, gluten-free products, and bioaromas. Food scientists, food technologists and nutrition researchers working on food applications and food processing will find this book extremely useful. In addition, those interested in the development of innovative products and functional foods will also benefit from this reference, as will students who study food chemistry, food science, technology, and food processing in postgraduate programs.

  • Mathematical Modelling in Motor Neuroscience: State of the Art and Translation to the Clinic, Gaze Orienting Mechanisms and Disease

    • 1st Edition
    • Volume 249
    • English
    Mathematical Modelling in Motor Neuroscience: State of the Art and Translation to the Clinic, Gaze Orienting Mechanisms and Disease, Volume 249, the latest release in the Progress in Brain Research series, highlights new advances in the field, with this new volume presenting interesting chapters on a variety of topics, including Sequential Bayesian updating, Maps and Sensorimotor Transformations for Eye-Head Gaze Shifts: Role of the Midbrain Superior Colliculus, Modeling Gaze Position-Dependent Opsoclonus, Eye Position-Dependent Opsoclonus in Mild Traumatic Brain Injury, Saccades in Parkinson's disease -- hypometric, slow, and maladaptive, Brainstem Neural Circuits for Fixation and Generation of Saccadic Eye Movements, and much more.

  • A Comprehensive Physically Based Approach to Modeling in Bioengineering and Life Sciences

    • 1st Edition
    • Riccardo Sacco + 2 more
    • English
    A Comprehensive Physically Based Approach to Modeling in Bioengineering and Life Sciences provides a systematic methodology to the formulation of problems in biomedical engineering and the life sciences through the adoption of mathematical models based on physical principles, such as the conservation of mass, electric charge, momentum, and energy. It then teaches how to translate the mathematical formulation into a numerical algorithm that is implementable on a computer. The book employs computational models as synthesized tools for the investigation, quantification, verification, and comparison of different conjectures or scenarios of the behavior of a given compartment of the human body under physiological and pathological conditions.

  • Three-Dimensional Electron Microscopy

    • 1st Edition
    • Volume 152
    • English
    Three-Dimensional Electron Microscopy, Volume 152 in the Methods in Cell Biology series, highlights new advances in the field, with this new volume presenting interesting chapters focusing on FIB-SEM of mouse nervous tissue: fast and slow sample preparation, Serial-section electron microscopy using ATUM - Automated Tape collecting Ultra-Microtome, Software for automated acquisition of electron tomography tilt series, Scanning electron tomography of biological samples embedded in plastic, Cryo-STEM tomography for Biology, CryoCARE: Content-aware denoising of cryo-EM images and tomograms using artificial neural networks, Expedited large-volume 3-D SEM workflows for comparative vertebrate microanatomical imaging, and many other interesting topics.

  • Preservatives and Preservation Approaches in Beverages

    Volume 15: The Science of Beverages
    • 1st Edition
    • Alexandru Grumezescu + 1 more
    • English
    Preservatives for the Beverage Industry, Volume Fifteen, a new release in The Science of Beverages series, is a valuable resource that discusses preservatives and their impact in the beverage industry, including potential health impacts. The book takes a broad, multidisciplinary approach to explore both conventional and novel approaches of the types and uses of preservatives. The latest applications and techniques to reduce the use of non-natural or health-threatening preservation elements are also covered. This is a must-have reference for anyone who needs to increase their technical-scientific knowledge in this field.

  • Comprehensive Biotechnology

    • 3rd Edition
    • Murray Moo-Young
    • English
    Comprehensive Biotechnology, Third Edition, Six Volume Set unifies, in a single source, a huge amount of information in this growing field. The book covers scientific fundamentals, along with engineering considerations and applications in industry, agriculture, medicine, the environment and socio-economics, including the related government regulatory overviews. This new edition builds on the solid basis provided by previous editions, incorporating all recent advances in the field since the second edition was published in 2011.

  • Carbonic Anhydrases

    Biochemistry and Pharmacology of an Evergreen Pharmaceutical Target
    • 1st Edition
    • Claudiu T. Supuran + 1 more
    • English
    Carbonic Anhydrases provides an interdisciplinary review of the burgeoning carbonic anhydrase (CA) research area, spanning from CAs classification (biochemical and structural features) to drug design and pharmacology of CA inhibitors and activators, finally touching on the biotechnological applications of these metalloenzymes. The book adopts a clear step-by-step approach and introduction to this intricate and highly interdisciplinary field. A diverse range of chapters from international experts speak to CA classification and distribution, the mechanisms of action and drug design of inhibitors and activators, the druggability of the various isoforms in the treatment of a multitude of diseases, and threats to human health. Carbonic Anhydrases provides biology, biochemistry, and medicinal chemistry students and researchers a thorough discussion and update on the evergreen and expanding research area of CAs.

  • Neonatal Neurology

    Handbook of Clinical Neurology Series
    • 1st Edition
    • Volume 162
    • English
    Neonatal Neurology, Volume 162 in the Handbook of Clinical Neurology, series updates the reader on the latest advances in the study of neurological diseases diagnosed in the fetal and neonatal periods. With recent advances in magnetic resonance imaging, digital electroencephalograp... recording, and genetic testing and diagnosis, there is expanding awareness relating to early onset neurological conditions and how their early diagnosis can improve prediction of outcome and subsequent neurodevelopmental outcome. This new volume covers diagnosis and management of congenital conditions, including brain malformations, neuromuscular conditions and genetic epilepsies, as well as acquired injury related to peri-partum events, prematurity, critical illness and systemic diseases.

  • Postharvest Technology of Perishable Horticultural Commodities

    • 1st Edition
    • Elhadi M. Yahia
    • English
    Postharvest Technology of Perishable Horticultural Commodities describes all the postharvest techniques and technologies available to handle perishable horticultural food commodities. It includes basic concepts and important new advances in the subject. Adopting a thematic style, chapters are organized by type of treatment, with sections devoted to postharvest risk factors and their amelioration. Written by experts from around the world, the book provides core insights into identifying and utilizing appropriate postharvest options for maximum results.

  • Advances in Clinical Chemistry

    • 1st Edition
    • Volume 91
    • English
    Advances in Clinical Chemistry, Volume 91, the latest release in this internationally acclaimed series, contains chapters authored by world-renowned clinical laboratory scientists, physicians and research scientists. The serial discusses the latest and most up-to-date technologies related to the field of clinical chemistry, providing the benchmark for novel analytical approaches in the clinical laboratory.

  • Neuropsicología

    • 7th Edition
    • Roger Gil
    • Spanish
    Este título permite adquirir los conocimientos de base, tanto anatómicos como fisiológicos, sobre el cerebro. Los autores ofrecen la posibilidad de revisar los principales trastornos cognitivos, emocionales y de la conducta. Se ha incluido un capítulo dedicado a la neuropsicología del envejecimiento y a los abordajes no farmacológicos de la enfermedad de Alzheimer. Obra dirigida a estudiantes de psicología, médicos residentes, estudiantes de logopedia y terapia ocupacional, neurólogos, logopedas, psiquiatras, geriatras, psicólogos y otros profesionales que participan en el tratamiento de pacientes con lesiones cerebrales.

  • Clinical Neurophysiology: Diseases and Disorders

    Handbook of Clinical Neurology Series
    • 1st Edition
    • Volume 161
    • English
    Clinical Neurophysiology: Diseases and Disorders, the latest release in the Handbook of Clinical Neurology series, reviews the current practice of clinical neurophysiology in the laboratory, by the bedside, and in the operating room or intensive care unit. The volume is organized into sections focused on diseases of the central and peripheral nervous systems, sleep disorders, and autonomic disorders. Among the CNS topics covered are epilepsy, altered states of consciousness, disorders of cognition, brain death, demyelinating diseases, stroke, pain, movement disorders, vestibular disease, and auditory disorders. Peripheral nervous system topics include focal mononeuropathies, generalized polyneuropathies, muscle diseases, hyperexcitability states, neuromuscular junction disorders, anterior horn cells diseases, and cranial neuropathies. There are also chapters on sleep apneas, hypersomnias, parasomnias, and circadian rhythm disorders. Autonomic topics include primary autonomic failure, multisystem atrophy, and postural orthostatic tachycardia syndrome.

  • Photobiomodulation in the Brain

    Low-Level Laser (Light) Therapy in Neurology and Neuroscience
    • 1st Edition
    • Michael R. Hamblin + 1 more
    • English
    Photobiomodulation in the Brain: Low-Level Laser (Light) Therapy in Neurology and Neuroscience presents the fundamentals of photobiomodulation and the diversity of applications in which light can be implemented in the brain. It will serve as a reference for future research in the area, providing the basic foundations readers need to understand photobiomodulation’s science-based evidence, practical applications and related adaptations to specific therapeutic interventions. The book covers the mechanisms of action of photobiomodulation to the brain, and includes chapters describing the pre-clinical studies and clinical trials that have been undertaken for diverse brain disorders, including traumatic events, degenerative diseases and psychiatric disorders.

  • Integrated Processing Technologies for Food and Agricultural By-Products

    • 1st Edition
    • Zhongli Pan + 2 more
    • English
    Feeding our globally expanding population is one of the most critical challenges of our time and improving food and agricultural production efficiencies is a key factor in solving this problem. Currently, one-third of food produced for humans is wasted, and for every pound of food produced, roughly an equal amount of nonfood by-product is also generated, creating a significant environmental impact. In Integrated Processing Technologies for Food and Agricultural By-Products experts from around the world present latest developments, recognizing that while some by-products have found use as animal feed or are combusted for energy, new technologies which integrate conversion of production and processing by-products into higher-value food or nonfood products, nutraceuticals, chemicals, and energy resources will be a critical part of the transition to a more sustainable food system. Organized by agricultural crop, and focusing on those crops with maximum economic impact, each chapter describes technologies for value-added processing of by-products which can be integrated into current food production systems. Integrated Processing Technologies for Food and Agricultural By-Products is a valuable resource for industry professionals, academics, and policy-makers alike.

  • Drug-Induced Liver Injury

    • 1st Edition
    • Volume 85
    • English
    Drug-Induced Liver Injury, Volume 85, the newest volume in the Advances in Pharmacology series, presents a variety of chapters from the best authors in the field. Chapters in this new release include Cell death mechanisms in DILI, Mitochondria in DILI, Primary hepatocytes and their cultures for the testing of drug-induced liver injury, MetaHeps an alternate approach to identify IDILI, Autophagy and DILI, Biomarkers and DILI, Regeneration and DILI, Drug-induced liver injury in obesity and nonalcoholic fatty liver disease, Mechanisms of Idiosyncratic Drug-Induced Liver Injury, the Evaluation and Treatment of Acetaminophen Toxicity, and much more.

  • Advances in Immunology

    • 1st Edition
    • Volume 142
    • Frederick W. Alt
    • English
    Advances in Immunology, Volume 142, the latest release in a long-established and highly respected publication, presents current developments and comprehensive reviews in immunology. Articles address the wide range of topics that comprise immunology, with this release focusing on the advancing area of the mechanisms involved in the evolution of HIV-1 neutralizing antibodies.

  • Math Calculations for Pharmacy Technicians custom e-book for Ross education (3e)

    • 3rd Edition
    • Ross Education
    • English

  • Clinical Neurophysiology: Basis and Technical Aspects

    Handbook of Clinical Neurology Series
    • 1st Edition
    • Volume 160
    • English
    Clinical Neurophysiology: Basis and Technical Aspects, the latest release in the Handbook of Clinical Neurology series, is organized into sections on basic physiological concepts, on the function and limitations of modern instrumentation, and on other fundamental or methodologic aspects related to the recording of various bioelectric signals from the nervous system for clinical or investigative purposes. There is discussion of the EEG, nerve conduction studies, needle electromyography, intra-operative clinical neurophysiology, sleep physiology and studies, the autonomic nervous system, various sensory evoked potentials, and cognitive neurophysiology.

  • Circadian Rhythm Disorders , An Issue of Neurologic Clinics

    • 1st Edition
    • Volume 37-3
    • Phyllis C. Zee
    • English
    This issue of Neurologic Clinics, guest edited by Dr. Phyllis C. Zee, with consulting editor Randolph W. Evans, will focus on Circadian Rhythm Disorders. Topics include, but are not limited to, Circadian biology, Genetic basis of circadian rhythms, Implication of circadian rhythm misalignment on sleep and health, Assessment of circadian rhythms, Circadian Rhythm sleep-wake phase disorders, Irregular sleep-wake rhythm sleep –wake disorder, Non-24 hour sleep-wake rhythm disorder, Shift Work Sleep Disorder, Challenging cases, and Future of circadian and sleep medicine.

  • Environmental Nutrition

    Connecting Health and Nutrition with Environmentally Sustainable Diets
    • 1st Edition
    • Joan Sabate
    • English
    Environmental Nutrition: Connecting Health and Nutrition with Environmentally Sustainable Diets explores the connection between diet, environmental sustainability and human health. Current food systems are a major contributor to our most pressing health and environmental issues, including climate change, water scarcity, food insecurity and chronic diseases. This book not only seeks to increase our understanding of the interrelatedness of these major global issues, but also aids in the creation of new solutions. Sections discuss the diet, the health and environment trilemma, food systems and their trends, environmental nutrition as an all-encompassing discipline, and the environmental nutrition model.

  • Delivery of Therapeutics for Biogerontological Interventions

    From Concepts to Experimental Design
    • 1st Edition
    • Wing-Fu Lai
    • English
    Delivery of Therapeutics for Biogerontological Interventions: From Concepts to Experimental Design provides tactics on how to facilitate planning and research in interventive biogerontology. The book helps create clearer directions for the translation of existing advances in delivery technologies, from lab to practice. It is ideal as a starting point for scientists, clinicians and those interested in the field of biogerontology, biomedicine or nanotechnology, comprehensively discussing how to translate bench works to practicable tactics that retard the aging process. Using support from recent advances reported in literature, this title takes advantage of delivery technologies to develop biogerontological interventions, from concept to experimental design.

  • Mosby’s Pharmacy Technician Exam Review

    • 4th Edition
    • James J. Mizner
    • English
    Prepare for success on your certification exam! Mosby's Pharmacy Technician Exam Review, 4th Edition provides a complete review of core knowledge, thousands of review questions, and nine practice exams – plus a custom online engine that allows for unlimited opportunities to practice specific topics or create unique simulated exams. A bulleted, outline format makes review easier, reinforcing understanding with full-color illustrations, photographs, and summary tables. All questions reflect the latest exam blueprints. This resource provides you comprehensive support every step of the way for entry-level or sterile compounding certification.

  • Dendrology: Cones, Flowers, Fruits and Seeds

    • 1st Edition
    • Marilena Idžojtić
    • English
    Dendrology: Cones, Flowers, Fruits and Seeds offers a comprehensive overview of the morphology of reproductive organs of woody plants of Europe in one resource. The book contains 2020 woody taxa (845 species, 58 subspecies, 38 varieties, 13 forms, 40 hybrids and 1026 cultivars), belonging to 400 genera and 121 families. It includes 447 taxa of trees and shrubs that are autochthonous in Europe and numerous ornamental species that originate from North America, Asia, South America, Australia and Africa, along with invasive woody species. Accompanied by thousands of original photographs, the book is designed to efficiently guide the reader to accurate identification. Other features include taxa organized in alphabetical order of their botanical names, flowering and fruiting time, mode of fruit or seed dispersal, and distribution range, making this a must-have reference for students and researchers in dendrology, botany, forestry, forest management and conservation, arboriculture and horticulture.

  • Polymeric Nanoparticles as a Promising Tool for Anti-cancer Therapeutics

    • 1st Edition
    • Prashant Kesharwani + 2 more
    • English
    Polymeric Nanoparticles as Promising Tool for Anti-cancer Therapeutics provides an understanding of polymeric compounds and their use in cancer therapies. The book begins by giving an overview of the current status, future challenges and potential utilization of polymeric nanoparticles. It then covers specific polymeric nanoparticles through contributions from world-renowned experts and researchers. Chapters examine specific polymeric nanoparticles, their development as potential targeted delivery systems, and cancer characteristics that can be targeted for therapy development. The book synthesizes current research trends in the field, thus enhancing existing knowledge of nanomedicine, drug delivery and therapeutic intervention strategies in human cancers. Users will find this to be an ideal reference for research scientists and those in the pharmaceutical and medical fields who are working to develop novel cancer therapies using nanoparticle-based delivery systems.

  • The Practical Handbook of Perioperative Metabolic and Nutritional Care

    • 1st Edition
    • M. Isabel T.D Correia
    • English
    Intended for any healthcare professional working with surgical patients, including medical students, residents, surgeons and internists, nurses, dieticians, pharmacists, and physical therapists, The Practical Handbook of Perioperative Metabolic and Nutritional Care focuses on topics from the history of surgery and metabolism, to organic response to stress. Based on clinical processes, the author explores screening, assessment, and the impact of nutritional status on outcomes, in addition to investigating nutritional requirements, including macronutrients and micronutrients. Chapters examine wound healing as well as metabolic and nutritional surgical preconditioning, including coverage of preoperative counseling, preoperative nutrition, and preoperative fasting. Physical exercise is addressed, as well as nutritional therapy in the form of oral supplements, and enteral and parenteral approaches. Additional topics explored include nutrition therapy complications and immunomodulatory nutrients, pro, pre and symbiotics, postoperative oral, enteral and parenteral nutrition, enteral access, vascular access, fluid therapy, and more. With up-to-date information, practical and cost-effective data, this resource is critical for translating theory to practice.

  • Nervous System Drug Delivery

    Principles and Practice
    • 1st Edition
    • Russell R. Lonser + 2 more
    • English
    Nervous System Drug Delivery: Principles and Practice helps users understand the nervous system physiology affecting drug delivery, the principles that underlie various drug delivery methods, and the appropriate application of drug delivery methods for drug- and disease-specific treatments. Researchers developing nervous system putative therapeutic agents will use this book to optimize drug delivery during preclinical assessment and to prepare for regulatory advancement of new agents. Clinicians will gain direct insights into pathophysiologic alterations that impact drug delivery and students and trainees will find this a critical resource for understanding and applying nervous system drug delivery techniques.

  • RNA Recognition

    • 1st Edition
    • Volume 623
    • English
    RNA Recognition, Volume 623, the latest volume in the Methods in Enzymology series, continues the legacy of this premier serial with quality chapters authored by leaders in the field. This updated volume covers a variety of topics, including The Preparation of cooperative RNA recognition complexes for crystallographic structural studies, Methods for thermal denaturation studies of fluorogenic aptamers, Dynamic combinatorial chemistry as a rapid, fragment-based approach to RNA-targeted compound discovery, Using a click chemistry assay to identify natural product ligands for pre-microRNAs, Lessons from exploration of chemical and structural small molecule:RNA space, Using ligand-observed NMR to study RNA-small molecule interactions, and much more.

  • Mathematical Modelling in Motor Neuroscience: State of the Art and Translation to the Clinic. Ocular Motor Plant and Gaze Stabilization Mechanisms

    • 1st Edition
    • Volume 248
    • English
    Mathematical Modelling in Motor Neuroscience: State of the Art and Translation to the Clinic. Ocular Motor Plant and Gaze Stabilization Mechanisms, Volume 248, the latest release in the Progress in Brain Research series, highlights new advances in the field, with this new volume presenting interesting chapters on a variety of topics, including Mathematical modeling in clinical and basic motor neuroscience, The math of medicine - the computational lessons learned from the human disease, Mathematical models - an extension of the clinician's mind, From differential equation to linear control systems: the study of the VOR, Closed lop and nonlinear systems, State-space equations and learning, Integrators and optimal control, and much more.

  • Natural Beverages

    Volume 13: The Science of Beverages
    • 1st Edition
    • Alexandru Grumezescu + 1 more
    • English
    Natural Beverages, Volume Thirteen, in the Science of Beverages series, takes a multidisciplinary approach to address the shifting beverage landscape towards the global trend of natural beverages. As global beverage consumption has progressed towards healthier and ‘natural’ ingredients, researchers and scientists need to understand the latest scientific developments and the proposed health benefits and improved effects. Classical examples are presented as a basis for innovation expansion to help new researchers understand this segment of the industry. This is a great resource for researchers and scientists in the beverages industry.

  • Handbook of Sleep Research

    • 1st Edition
    • Volume 30
    • English
    Handbook of Sleep Research, Volume 30, provides a comprehensive review of the current status of the neuroscience of sleep research. It begins with an overview of the neural, hormonal and genetic mechanisms of sleep and wake regulation before outlining the various proposed functions of sleep and the role it plays in plasticity, and in learning and memory. Finally, the book discusses disorders of sleep and waking, covering both lifestyle factors that cause disrupted sleep and psychiatric and neurological conditions that contribute to disorders.

  • Taylor's Power Law

    Order and Pattern in Nature
    • 1st Edition
    • R.A.J. Taylor
    • English
    Taylor's Power Law: Order and Pattern in Nature is a broad synthesis of this ubiquitous property of natural and man-made phenomena. This stimulating and approachable work surveys the biological and non-biological empirical data, describes the statistical uses of Taylor’s power law (TPL) and its relationship to statistical distributions, exposes the mathematical connections to other power laws, covers the competing explanatory models; and develops an argument for TPL's genesis. Taylor’s power law relates the variability of a process or population to its average value. It was first described in relation to insect populations and then more broadly to other animal and plant populations. Subsequently it has been recognized in microbiology, genetics, economics, astronomy, physics, and computer science, and it is thought to be one of the few general laws in ecology where it is routinely used to describe the spatial and temporal distributions of populations. Biologists who know the law as Taylor's power law and physical scientists who know it as fluctuation scaling will be interested in the bigger picture on this fascinating subject. As the relationship between variance and mean is found in so wide a range of disciplines, it seems possible it is a deep property of number, not just a phenomenon in ecology as was thought originally. Although theories abound that purport to explain or predict TPL, none is entirely satisfactory either because it fails to be very predictive, or it does not account for all the available empirical data. To uncover such a property requires a synthesis across disciplines, an acute need that is approached by this exciting work.

  • Encyclopedia of Pharmacy Practice and Clinical Pharmacy

    • 1st Edition
    • Zaheer-Ud-Din Babar
    • English
    Encyclopedia of Pharmacy Practice and Clinical Pharmacy, Four Volume Set covers definitions, concepts, methods, theories and applications of clinical pharmacy and pharmacy practice. It highlights why and how this field has a significant impact on healthcare. The work brings baseline knowledge, along with the latest, most cutting-edge research. In addition, new treatments, algorithms, standard treatment guidelines, and pharmacotherapies regarding diseases and disorders are also covered. The book's main focus lies on the pharmacy practice side, covering pharmacy practice research, pharmacovigilance, pharmacoeconomics, social and administrative pharmacy, public health pharmacy, pharmaceutical systems research, the future of pharmacy, and new interventional models of pharmaceutical care.By providing concise expositions on a broad range of topics, this book is an excellent resource for those seeking information beyond their specific areas of expertise. This outstanding reference is essential for anyone involved in the study of pharmacy practice.

  • Role of Plant Growth Promoting Microorganisms in Sustainable Agriculture and Nanotechnology

    • 1st Edition
    • Ajay Kumar + 2 more
    • English
    Role of Plant Growth Promoting Microorganisms in Sustainable Agriculture and Nanotechnology explores PGPMs (actinomycetes, bacteria, fungi and cyanobacteria) and their multidimensional roles in agriculture, including their increasing applications in sustainable agriculture. In addition to their traditional understanding and applications in agriculture, PGPMs are increasingly known as a source of nano-particles production that are gaining significant interest in their ability to provide more economically, environmentally friendly and safe technologies to crop growers. The book considers new concepts and current developments in plant growth, thus promoting microorganisms research and evaluating its implications for sustainable productivity. Users will find this to be an invaluable resource for researchers in applied microbial biotechnology, soil science, nano-technology of microbial strains, and industry personnel in these areas.

  • Advances in Marine Biology

    • 1st Edition
    • Volume 82
    • English
    Advances in Marine Biology, Volume 82, the latest release in a series that has been providing in-depth and up-to-date reviews on all aspects of marine biology since 1963, updates on many topics that will appeal to postgraduates and researchers in marine biology, fisheries science, ecology, zoology and biological oceanography. Chapters in this new release include Predatory Bivalves, The Oceanography of the Eastern English Channel Past: Present and Future, Parasites and Pathogens in Seabirds: Effects and Wider Ecological Implications, Progress in Marine Genomics and Bioinformatics, and more.

  • Pharmacology of Restless Legs Syndrome (RLS)

    • 1st Edition
    • Volume 84
    • English
    Pharmacology of Restless Legs Syndrome (RLS), Volume 84, the newest volume in the Advances in Pharmacology series, presents a variety of chapters from the best authors in the field on essential topics, with this volume presenting chapters on Targeting the adenosinergic system in Restless Legs Syndrome, Assessing iron uptake mechanisms in the brain: impact of gender and genotype, Pharmacological treatments of RLS in augmentation, C. elegans and its applicability to studies on RLS, The neurophysiology of hyperarousal in RLS: hints for a role of glutamate/GABA, Treatment management and options in RLS patients, Pharmacological responsiveness of Periodic Legs Movements during Sleep, and more.

  • Value-Added Ingredients and Enrichments of Beverages

    Volume 14: The Science of Beverages
    • 1st Edition
    • Alexandru Grumezescu + 1 more
    • English
    Value-Added Ingredients and Enrichment of Beverages, Volume Fourteen in The Science of Beverages series, takes a multidisciplinary approach in addressing what consumers demand in natural beverages. This in-depth reference covers both natural and unnatural ingredients and explains their impact on consumer health and nutrition. Sweeteners, vitamins, oils and other natural ingredients to improve beverages are included. The book addresses some of the most common enrichments used in the industry, including those with biomedical and nutritional applications. This volume will be useful to anyone in the beverages industry who needs a better understanding of advances in the industry.

  • Arousal in Neurological and Psychiatric Diseases

    • 1st Edition
    • Edgar Garcia-Rill
    • English
    Arousal in Neurological and Psychiatric Diseases focuses on the dysregulation of arousal found in many neurological and psychiatric disorders. Chapters describe the physiology of each process, how it presents in each disorder, and the most appropriate treatment(s). The book also imparts the understanding of the RAS as a system that not only modulates waking, but also survival mechanisms, such as fight vs. flight responses and other reflexes. This book helps neuroscientists, sleep researchers, neurologists and psychiatrists understand the basic mechanisms that modulate arousal in health and disease. In addition, it promotes therapies that can alter the severity and manifestation of multiple disorders.

  • The Theory of Endobiogeny

    Volume 1: Global Systems Thinking and Biological Modeling for Clinical Medicine
    • 1st Edition
    • Kamyar M. Hedayat + 1 more
    • English
    The Theory of Endobiogeny Volume 1: Global Systems Thinking and Biological Modeling for Clinical Medicine offers researchers and clinicians a detailed introduction to the theory of Endobiogeny. The book presents a new approach to medicine that is at once scientific and humanistic, quantitative, and qualitative. The philosophical and experimental basis of a global complex systems approach to physiology is presented along with a mathematical approach to modeling the dynamism of the terrain. The importance of the history and physical examination are renewed as a source of “big data” readily available to clinicians for greater insight into the patient’s state. Expansion of the therapeutic compendium is proposed based on a rational, clinical approach correlated to mathematical indicators of the physiologic state. What is proposed in this work is a fundamental shift in scientific thinking with a resulting expansion of the boundaries of clinical medicine for the 21st century and beyond.

  • The Theory of Endobiogeny

    Volume 2: Foundational Concepts for Treatment of Common Clinical Conditions
    • 1st Edition
    • Kamyar M. Hedayat + 1 more
    • English
    The Theory of Endobiogeny Volume 2: Foundational Concepts for Treatments of Common Clinical Conditions addresses the core elements of the adaptation response to stressors: autonomic nervous system (ANS), corticotropic axis, immunity and digestive tract function. The volume is oriented for clinical practice, offering clear discussions on treating the root cause of numerous common disorders, and symptomatically addressing the destabilizing factor in a vast number of disorders ranging from depression to irritable bowel, and from migraines to insomnia called spasmophilia.

  • Reducing Salt in Foods

    • 2nd Edition
    • Cindy Beeren + 2 more
    • English
    Reducing Salt in Foods, Second Edition, presents updated strategies for reducing salt intake. The book contains comprehensive information on a wide range of topics, including the key health issues driving efforts to reduce salt, government action regarding salt reduction and the implications of salt labeling. Consumer perceptions of salt and views on salt reduction in different countries are also discussed, as are taste, processing and preservation functions of salt and salt reduction strategies. Final sections discuss salt reduction in particular food groups, including meat and poultry, seafood, bread, snack foods, dairy products and canned foods, each one including a case study. This updated edition also includes a new section on the future of salt reduction, the development of new ingredients to replace salt, salt reduction in catering, and how to teach new generations to adjust salt levels from an early age.

  • Oligodendroglioma

    Clinical Presentation, Pathology, Molecular Biology, Imaging, and Treatment
    • 1st Edition
    • Nina A. Paleologos + 1 more
    • English
    Oligodendroglioma: Clinical Presentation, Pathology, Molecular Biology, Imaging, and Treatment features the latest "cutting-edge" molecular biology, molecular therapeutics, imaging, immunotherapy, and research methods on the topic of oligodendrogliomas. The most detailed and comprehensive resource on the subject, it provides up-to-date information on clinical presentation, pathology, molecular biology, and treatment methods, including immunotherapy. This book is a critical for students, physicians and researchers in the fields of neuroscience, neuro-oncology, neurosurgery, radiation oncology, medical oncology, and others working in research or with patients.

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