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Elsevier

Books in Chemistry

Chemistry topic areas include: physical and theoretical, computational, organic, organometallic and inorganic, pharmaceutical and medicinal, analytical and bioanalytical, nuclear, general, nanochemistry, geochemistry, materials and polymer, as well as environmental, green and sustainable chemistry.

  • Molecular and Chemical Physics, Chemistry, Biological Effects, Geo and Planetary Sciences, New Resources, Dynamic Pressures, High Pressure Safety

    Proceedings of the VIIth International AIRAPT Conference (Organised Jointly with the EHPRG), Le Creusot, France, July 30 - August 3, 1979
    • 1st Edition
    • B. Vodar + 1 more
    • English
    High Pressure Science and Technology, Volume 2 contains the proceedings of the Association Internationale for Research and Advancement of High Pressure Science and Technology's VIIth International Conference held in Le Creusot, France, from July 30 to August 3, 1979. The papers explore a wide range of topics relating to high pressure science and technology, including molecular and chemical physics; melting and dense fluids; liquid crystals; molecular thermophysical properties; light scattering; intermolecular spectroscopy; high-temperature, high-pressure fluids; and properties of earth materials. This volume is comprised of 128 chapters and begins by calculating equations of state for static molecular and metallic hydrogen using the density functional method. The following chapters discuss the effect of density on the induced near infrared absorption spectrum of solid molecular hydrogen at 4.2 K; vibrational relaxation in highly compressed hydrogen; the dual melting curves of carbon tetrachloride; and the statistical theory of polymorphic phase transitions and crystallization. Alkane chain conformation as a function of pressure is also examined, along with high pressure thermodynamics and phase equilibria of fluid mixtures. The remaining sections focus on the lithosphere, athenosphere, and the behavior of dense materials. This book will be a valuable resource for materials scientists, metallurgists, physicists, chemists, and mechanical engineers.

  • Strategies for Palladium-Catalyzed Non-directed and Directed C bond H Bond Functionalization

    • 1st Edition
    • Anant R. Kapdi + 1 more
    • English
    Strategies for Palladium-Catalyzed Non-directed and Directed C-H Bond Functionalization portrays the complete scope of these two aspects of C-H bond functionalization in a single volume for the first time. Featured topics include the influence of palladacyclic systems in C-H bond functionalization (need for newer catalytic systems for better efficiency), mechanistic aspect of the functionalization strategies leading to better systems, and applications of these methodologies to natural product synthesis and material synthesis.

  • Immunosensing for Detection of Protein Biomarkers

    • 1st Edition
    • Huangxian Ju + 2 more
    • English
    Immunosensing for Detection of Protein Biomarkers not only introduces the principles, methods, and classification of immunoassay, but also presents the latest achievements in areas such as electrochemical immunosensors, nanoprobe-based immunoassay, chemiluminescence immunoassay, electrochemiluminesc... immunoassay, multianalyte immunoassay, optical imaging for immunoassay, signal amplification for immunoassay, and so on. In recent years, immunosensing and immunoassay methods have attracted considerable interest due to their applications in different fields, particularly clinical diagnosis. Although a large number of academic papers in immunosensing and immunoassay have been published in different journals recently, it is still a difficult and time-consuming task for researchers, especially those new to the area, to understand the principles, methods, and research progress of immunosensing. Based on the research experience of the authors and their research groups, this book offers readers with new research ideas to develop immunosensing methodology. As a monograph, it offers deeper and more complete coverage than review papers, which only report certain aspects of progress. Grounded in the research experience of Professor Ju’s research group, the book focuses on immunosensing for detection of protein biomarkers, summarizing understanding, research, and practice on immunosensing methodology in detection of protein biomarkers.

  • Discovery and Development of Neuroprotective Agents from Natural Products

    • 1st Edition
    • Goutam Brahmachari
    • English
    Discovery and Development of Neuroprotective Agents from Natural Products draws together global research on medicinal agents from natural sources as starting points for the design of neuroprotective drugs. From the prediction of promising leads and identification of active agents to the extraction of complex molecules, the book explores a range of important topics to support the development of safer, more economical therapeutics for these increasingly prevalent diseases. Beginning with an overview of current developments in the field, the book goes on to explore the identification, extraction and phytochemistry of such neuroprotective agents as antioxidants, biophenols and naturally occurring anti-inflammatory steroid analogues. Specific natural sources of bioactive agents are reviewed, and the development of these agents into therapeutics for a number of specific neurological disorders, including Alzheimer’s disease, Parkinson’s disease and ischemic brain stroke, are discussed. Combining the expertise of specialists from around the world, this in the Natural Products Drug Discovery series aims to support and encourage researchers in the investigation of natural sources as starting points for the development of standardized, safe and effective neuroprotective drugs.

  • Fluorescence and Phosphorescence Spectroscopy

    Physicochemical Principles and Practice
    • 1st Edition
    • Stephen G Schulman
    • R. Belcher + 1 more
    • English
    Fluorescence and Phosphorescence Spectroscopy: Physicochemical Principles and Practice deals with the physicochemical principles and applications of fluorescence and phosphorescence spectroscopy in experimental biology and chemistry. Topics covered include the absorption of light by molecules; instrumentation for the measurement of fluorescence and phosphorescence; solvent and acidity effects on electronic spectra; and polarization of fluorescence and phosphorescence. Comprised of four chapters, this book begins with a discussion on photophysical processes in isolated molecules and molecules in solution, paying particular attention to thermal equilibration of electronically excited molecules, phototautomerism, and coordination by metal ions. The next chapter describes the instrumentation for measuring fluorescence and phosphorescence, which consists essentially of a light source to electronically excite the sample; a monochromator to separate the light of desired energy from the source; a sample compartment; a second monochromator to isolate the sample's fluorescence energy from the excitation energy; a photodetector to translate the fluorescent light into an electrical signal; and a readout system such as a galvanometer or a recorder, coupled with an amplifier to determine the intensity of fluorescent light that is emitted. The final chapter is devoted to various applications of fluorescence and phosphorescence spectroscopy, including the analysis of organic and inorganic compounds. This monograph is written primarily for analytical chemists and biological scientists.

  • Carbon Dioxide in Non-aqueous Solvents at Pressures Less Than 200 KPA

    • 1st Edition
    • Volume 50
    • P.G.T. Fogg
    • English
    Solubility Data Series, Volume 50: Carbon Dioxide in Non-Aqueous Solvents at Pressures Less Than 200 kPa contains evaluated data for the solubility in non-aqueous solvents of carbon dioxide at a partial pressure not greater than 200 kPa. The Solubility Data Series is a project of Commission V.8 (Solubility Data) of the International Union of Pure and Applied Chemistry (IUPAC). The text has as its goal the preparation of a comprehensive and critical compilation of data on solubilities in all physical systems, including gases, liquids and solids. Chapters are devoted to providing data on the solubility of carbon dioxide in compounds such as alkanes, cyclic alkanes and alkenes, alcohols, solvents, other than alcohols, containing carbon, hydrogen and oxygen, and animal and vegetable oils and fats. Chemists will find the text extremely useful.

  • Molecular Diseases

    FEBS Federation of European Biochemical Societies: 12th Meeting, Dresden, 1978
    • 1st Edition
    • G. Jacobasch + 1 more
    • English
    Molecular Diseases, Volume 56 presents the interrelated problems of synthesis, assembly, and breakdown of the various organelles of the cell for which powerful methods have been developed. This book discusses the processing of virus-coded proteins. Organized into nine chapters, this volume begins with an overview of the primary causes that can account for the hereditary defects of enzyme activity. This text then examines the basic methodological aspects of the assessment of protein turnover in a complex intact mammalian organism. Other chapters consider the method of desialylation of erythrocytes and their in vivo and in vitro behavior after this treatment. This book discusses as well the interrelationship between the peroxidatic enzymes and superoxide dismutase in the red cell. The final chapter deals with the use of liposomes as enzyme carriers in the treatment of lysosomal storage diseases. This book is a valuable resource for biological and medical students in various fields.

  • Development Theories and Methods of Fracture-Vug Carbonate Reservoirs

    • 1st Edition
    • Yang Li
    • English
    Development Theories and Methods of Fracture-Vug Carbonate Reservoirs explores the theories and methods for successful development of a fracture-vug reservoir by presenting the developmental strategies used in the Tahe oilfield. Some of the theories and methods of developing the Tahe fracture-vug reservoirs have been inspired by two China national research projects: The ‘Basic research on development of fracture-vug carbonate reservoirs’ (2006-2010), and the ‘Basic research on production mechanism and oil recovery enhancement of fracture-vugcarbonat... reservoirs’ (2011-2015), with support by the National Basic Research Program of China. These theories and methods have facilitated the successful development of the fracture-vug reservoir in the Tahe oilfield, providing effective technologies and inspirations to developing similar reservoirs everywhere.

  • Polymer Processing

    Principles and Modelling
    • 1st Edition
    • Jean-François Agassant + 4 more
    • English
    Engineering of polymers is not an easy exercise: with evolving technology, it often involves complex concepts and processes. This book is intended to provide the theoretical essentials: understanding of processes, a basis for the use of design software, and much more. The necessary physical concepts such as continuum mechanics, rheological behavior and measurement methods, and thermal science with its application to heating-cooling problems and implications for flow behavior are analyzed in detail. This knowledge is then applied to key processing methods, including single-screw extrusion and extrusion die flow, twin-screw extrusion and its applications, injection molding, calendering, and processes involving stretching. With many exercises with solutions offered throughout the book to reinforce the concepts presented, and extensive illustrations, this is an essential guide for mastering the art of plastics processing. Practical and didactic, Polymer Processing: Principles and Modeling is intended for engineers and technicians of the profession, as well as for advanced students in Polymer Science and Plastics Engineering.

  • The Chemistry of Chlorine, Bromine, Iodine and Astatine

    Pergamon Texts in Inorganic Chemistry, Volume 7
    • 1st Edition
    • A. J. Downs + 1 more
    • English
    The Chemistry of Chlorine, Bromine, Iodine and Astatine is a special edition that contains selected sections and addresses the needs of specialists in their respective fields. The text describes the general atomic properties of non-metals, particularly the halogens, as being the perfect series to study, both in physical and chemical terms. The book explains that the combination of the atomic properties implies excellent electronegativity values for the halogen atoms. The text also cites some behavior characteristics of halogens that are irregular, such as chlorine and bromine are similar but differ from fluorine on one side and iodine on the other. The book also compares the general methods of producing chlorine, bromine, or iodine by 1) oxidation of halide derivatives or 2) reduction of compounds of the halogens in positive oxidation states. The text then reviews the application of a complex valence theory that raises difficult questions about the bonding in halogen-oxygen molecules. The book also explains the biological behavior of astatine that accumulates in the liver or in the thyroid gland depending on the method of administration either as a radiocolloid or as a true solution. The book is suitable for molecular biologists and researchers, molecular chemists, and medical researchers.

  • Liquid Metals

    International Series of Monographs In: Natural Philosophy
    • 1st Edition
    • N. H. March
    • D. Ter Haar
    • English
    Liquid Metals covers topics about the properties of liquid metals, with emphasis on the microscopic description of the electron states. The book discusses radial distribution function, which is the quantitative way by which the structure of a monatomic fluid may be described, and the scattering of X-rays (or neutrons) from the fluid. The text describes the way by which the forces operating in liquid metals may be qualitatively described; the theory of electron screening in metals; the shielding of a structureless ion core in the Born approximation; and ways by which the structure of the ion core can profoundly influence the shielding. The forces operating between ions in liquid metals; the properties of solid metals; the time-dependent generalization of the structure factor; the dynamics of fluids from inelastic neutron scattering; and the nature of the energy level spectrum of the electrons in a liquid metal are also considered. Students of elementary quantum mechanics and statistical thermodynamics and physicists will find the book invaluable.

  • The Chemistry of the Metallic Elements

    The Commonwealth and International Library: Intermediate Chemistry Division
    • 1st Edition
    • David J. Steele
    • J. E. Spice
    • English
    The Chemistry of the Metallic Elements provides a concise yet comprehensive discussion of the structural principles of metallic elements. The book also provides tables that layout the data concerning the more common metals and their compounds. The text first covers the general information about the metallic elements, such as their physical properties, chemical properties, occurrence, and extraction. The subsequent chapters detail the elements and their compounds in context to their structure, and position in the periodic table and in the electrochemical series. The book will be of great use to researchers and practitioners of chemistry and chemical engineering.

  • Tenth International Symposium on Chemical Reaction Engineering

    Basle, Switzerland, 29 August – 1 September 1988
    • 1st Edition
    • J. R. Bourne + 2 more
    • English
    ISCRE 10 Tenth International Symposium on Chemical Reaction Engineering documents the proceedings of the symposium which brought together experts from all over the world to discuss developments in CRE. Efforts were made to cover high added value substances and to encourage papers from industry. Some success was achieved, but there remain significant gaps between Chemists and Chemical Engineers when considering high added value products as well as between researchers and practitioners of CRE. The volume begins with plenary papers covering topics such as challenges in reactor modeling; bioreactor engineering; the design of reaction systems for specialty organic chemicals. This is followed by papers presented during the eight technical sessions. Technical session A focused on the modeling and control of chemical reactions. Technical session B was devoted to studies on biotechnology. Technical session C covered mixing while Technical session D dealt with special reactor systems and chemicals. The papers in Technical session E examined reactions for emission control and recycling. Technical session F covered the safety aspects of CRE. Technical session G focused on the experiments with multiphase reactions while Technical session H dealt with catalytic reactors.

  • Frontiers of Bioorganic Chemistry and Molecular Biology

    Proceedings of the International Symposium on Frontiers of Bioorganic Chemistry and Molecular Biology, Moscow and Tashkent, USSR, 25 September - 2 October 1978
    • 1st Edition
    • S. N. Ananchenko
    • English
    Frontiers of Bioorganic Chemistry and Molecular Biology covers the proceedings of the International Symposium on Frontiers of Bioorganic Chemistry and Molecular Biology, held in Moscow and Tashkent, USSR on September 25-October 2, 1978. This symposium is devoted to a discussion of the physico-chemical basis of life processes. This book contains 56 chapters, and reflects the results in the study of peptides and proteins, nucleic acids, polysaccharides, and other biopolymers. Other chapters deal with the study of low molecular regulators, including steroids, alkaloids, and antibiotics. This book also includes discussion of the achievements in the study of genetic structures and of cellular protein synthesizing systems of the molecular basis of enzymic catalysis and of bioenergetic processes. This book will be of value to biochemists and molecular biologists.

  • Reaction Heats and Bond Strengths

    Based on a Series of Lectures Given to Postgraduate Students at the University of Keele, 1960
    • 1st Edition
    • C. T. Mortimer
    • English
    Reaction Heats and Bond Strengths presents the variations in the heats of particular types of reaction. This book covers a variety of topics, including the hydrogenation and polymerization of olefinic compounds, the dissociation of organic and organo-metallic compounds, and the molecular-addition compounds. Organized into 10 chapters, this book begins with an overview of the concept of bond energy that can be very useful where a comparison is being made between two dissimilar molecules. This text then examines the strain in cyclopropane and cyclobutane, which is largely a result of angular strain due to compression of the tetrahedral angle in the carbon–carbon bonding. Other chapters consider the experimental thermochemical data for some conjugated molecules. This book discusses as well the significance of representing a molecule, which originated from the concept of resonance. The final chapter deals with bond strength in phosphorus, silicon, and sulfur compounds. This book is a valuable resource for postgraduate students.

  • Compendium of Analytical Nomenclature

    Definitive Rules 1977
    • 1st Edition
    • H. M. N. H. Irving + 2 more
    • English
    Compendium of Analytical Nomenclature: Definitive Rules 1977 focuses on the recommended nomenclature and symbols to be used in various disciplines of analytical chemistry. The book first offers information on recommendations for the presentation of the results of chemical analysis; recommendations for terminology to be employed with precision balances; and recommendations on nomenclature for contamination phenomena in precipitation from aqueous solution. The text also takes a look at recommended nomenclature for automatic analysis and recommendations for nomenclature of thermal analysis and mass spectrometry, as well as recommended nomenclature for titrimetric analysis. The publication reviews the practical measurements of pH in amphiprotic and mixed solvents. Topics include operational pH scale; selection of a pH unit for amphiprotic solvents; and interpretation of the measured pH. The text also considers the recommendations on nomenclature and presentation of data in gas chromatography and recommendations on nomenclature for chromatography. The book is a valuable source of data for readers wanting to study analytical nomenclature.

  • Alkaloids: Chemical and Biological Perspectives

    • 1st Edition
    • Volume 9
    • S.W. Pelletier
    • English
    This monograph series provides unprecedented interdisciplinary coverage of research relating to the chemistry and biological properties of alkaloids - a class of biologically active compounds of more than 10,000 members. Timely, comprehensive and authoritative, the series features chapters on chemical properties and structure elucidation, synthesis, biosynthesis, taxonomy, spectroscopy, pharmacology, toxicology, and X-ray crystallography of alkaloids. The chapters are written and reviewed by eminent researchers, all of them acknowledged experts in the field. Subject and organism indexes are included for each volume.

  • Advanced Inorganic Chemistry

    Applications in Everyday Life
    • 1st Edition
    • Narayan S. Hosmane
    • English
    Advanced Inorganic Chemistry: Applications in Everyday Life connects key topics on the subject with actual experiences in nature and everyday life. Differing from other foundational texts with this emphasis on applications and examples, the text uniquely begins with a focus on the shapes (geometry) dictating intermolecular forces of attractions, leading to reactivity between molecules of different shapes. From this foundation, the text explores more advanced topics, such as: Ligands and Ligand Substitution Processes with an emphasis on Square-Planar Substitution and Octahedral Substitution Reactions in Inorganic Chemistry and Transition Metal Complexes, with a particular focus on Crystal-Field and Ligand-Field Theories, Electronic States and Spectra and Organometallic, Bioinorganic Compounds, including Carboranes and Metallacarboranes and their applications in Catalysis, Medicine and Pollution Control. Throughout the book, illustrative examples bring inorganic chemistry to life. For instance, biochemists and students will be interested in how coordination chemistry between the transition metals and the ligands has a direct correlation with cyanide or carbon monoxide poisoning (strong-field Cyanide or CO ligand versus weak-field Oxygen molecule).

  • Studies in Natural Products Chemistry

    • 1st Edition
    • Volume 53
    • Atta-ur Rahman
    • English
    Studies in Natural Products Chemistry, Volume 53, covers the synthesis, testing, and recording of the medicinal properties of natural products, providing cutting-edge accounts of the fascinating developments in the isolation, structure elucidation, synthesis, biosynthesis, and pharmacology of a diverse array of bioactive natural products. Natural products in the plant and animal kingdom offer a huge diversity of chemical structures that are the result of biosynthetic processes that have been modulated over the millennia through genetic effects. With the rapid developments in spectroscopic techniques and accompanying advances in high-throughput screening techniques, it has become possible to isolate and then determine the structures and biological activity of natural products rapidly, thus opening up exciting opportunities in the field of new drug development to the pharmaceutical industry that are discussed and highlighted in this series.

  • Advances in Clinical Chemistry

    • 1st Edition
    • Volume 80
    • English
    Advances in Clinical Chemistry, Volume 80, the latest installment in this internationally acclaimed series, covers a variety of topics relating to the topic. Users will find new chapters on Triglycerides Revisited to the Serial, PCR-Based Detection Methods for Single Nucleotide Polymorphism or Mutation: Real-Time PCR and its Substantial Contribution Towards Technological Refinement, Advances in Circulating Tumor DNA Analysis, Advances in Molecular Diagnosis of Malaria, and Rapid Assessment of Drugs of Abuse. This series contains chapters authored by world-renowned clinical laboratory scientists, physicians and research scientists who discuss the latest and most up-to-date technologies related to the field of clinical chemistry. Users of this series will find a resource that is considered to be the benchmark for novel analytical approaches in the clinical laboratory.

  • Algal Green Chemistry

    Recent Progress in Biotechnology
    • 1st Edition
    • Rajesh Prasad Rastogi + 2 more
    • English
    Algal Green Chemistry: Recent Progress in Biotechnology presents emerging information on green algal technology for the production of diverse chemicals, metabolites, and other products of commercial value. This book describes and emphasizes the emerging information on green algal technology, with a special emphasis on the production of diverse chemicals, metabolites, and products from algae and cyanobacteria. Topics featured in the book are exceedingly valuable for researchers and scientists in the field of algal green chemistry, with many not covered in current academic studies. It is a unique source of information for scientists, researchers, and biotechnologists who are looking for the development of new technologies in bioremediation, eco-friendly and alternative biofuels, biofertilizers, biogenic biocides, bioplastics, cosmeceuticals, sunscreens, antibiotics, anti-aging, and an array of other biotechnologically important chemicals for human life and their contiguous environment. This book is a great asset for students, researchers, and biotechnologists.

  • Validamycin and Its Derivatives

    Discovery, Chemical Synthesis, and Biological Activity
    • 1st Edition
    • Xiaolong Chen + 3 more
    • English
    Validamycin and Its Derivatives: Discovery, Chemical Synthesis and Biological Activity presents, for the first time, a complete review of the underlying chemistry, synthesis, behavior and application of these compounds. Beginning with an introduction to validamycin, the book then outlines the key elements of its discovery and production, including details of its structures, isolation, analysis, and issues relating to its large scale production. Biological activities are then explored in more detail, followed by details of biosynthesis. Further to this, the chemical synthesis of validamycin and its intermediates, including valienamine, validamine, valiolamine, and validoxylamines is reviewed, before preparation of these derivatives and their biological activities are explored. Finally, the book concludes with a discussion of the economic aspects of working with validamycin and its potential in future applications and trends. With its detailed chemical coverage from a team of expert authors, this detailed guide can be applied to the large-scale industrial production of antibiotics and the adaptation of bioactive agents, from agricultural, to novel pharmaceutical applications.

  • Dehydroacetic Acid and Its Derivatives

    Useful Synthons in Organic Synthesis
    • 1st Edition
    • Santhosh Penta
    • English
    Dehydroacetic Acid and Its Derivatives: Useful Synthons in Organic Synthesis outlines the use of DHA and its derivatives for the synthesis of pharmacologically active heterocyclic compounds. Beginning with an introduction to the chemistry and reactivity of Dehydroacetic Acid, the book goes on to outline the key ring transformation reactions of DHA. The synthesis of various derivatives is then discussed, before a wide range of metal complexes of DHA are explored in detail. The book then concludes with a review of DHA’s biological importance and its impressive range of pharmacological activities, including anti-cancer, anti-bacterial, anti-fungal and analgesic properties. For those researching the synthesis of bioactive heterocyclic compounds, this book is a valuable guide on the fundamental knowledge needed to facilitate and enhance the successful synthesis of lead molecules.

  • Advances in Heterocyclic Chemistry

    • 1st Edition
    • Volume 123
    • English
    Advances in Heterocyclic Chemistry, Volume 123 brings together the fields of biology and organic chemistry, highlighting the ways they increasingly intersect. This updated volume includes a section on new developments in tetrazole chemistry, a section on the synthesis and applications of thiophene derivatives as organic materials, and a synopsis of the properties and applications on heteroaromatic rings in medicinal chemistry. Written by established authorities from around the world, this comprehensive review combines descriptive synthetic chemistry and mechanistic insight to yield an understanding of how chemistry drives the preparation and useful properties of heterocyclic compounds. This definitive series in the field will be of great value to organic chemists, polymer chemists and many biological scientists.

  • Advances in Heterocyclic Chemistry

    • 1st Edition
    • Volume 122
    • English
    Advances in Heterocyclic Chemistry is the definitive series in the field—one of great importance to organic chemists, polymer chemists and many biological scientists. As the most recent release in the series, this book specifically focuses on new developments in the chemistry of 3-Arylisoxazoles and 3-Aryl-2-isoxazoline... and the synthesis of hererocycles from Amidrazones, amongst other important updates. Written by established, global authorities in the field, this comprehensive, continuously updated, longstanding series combines descriptive synthetic chemistry and mechanistic insight to yield an understanding on how chemistry drives the preparation and useful properties of heterocyclic compounds.

  • Annual Reports on NMR Spectroscopy

    • 1st Edition
    • Volume 91
    • English
    Annual Reports on NMR Spectroscopy, Volume 91 provides a thorough and in-depth accounting of progress in nuclear magnetic resonance (NMR) spectroscopy and its many applications for chemists and physicists to study the structure and dynamics of molecules. This updated release in the series focuses on topics surrounding NMR relaxation in dendrimers, MRI studies of spatial distribution of charge carriers, and MRI studies of plastic crystals, amongst other timely topics. As no other technique has gained as much significance as NMR spectroscopy in recent years, this series, for both specialists and non-specialists, is an ideal resource for the latest information in the field.

  • Progress in Medicinal Chemistry

    • 1st Edition
    • Volume 56
    • English
    Progress in Medicinal Chemistry, Volume 56 provides a review of eclectic developments in medicinal chemistry. This volume includes chapters covering recent advances in cancer therapeutics, fluorine in medicinal chemistry, a perspective on the next generation of antibacterial agents derived by manipulation of natural products, a potential new era for Chagas Disease drug discovery, and imaging in drug development. Specific chapters cover timely topics, such as the development of LRRK2 inhibitors for the treatment of Parkinson's, and recent discoveries and developments in TRPA1 modulators. Users will find a comprehensive resource on the topic of medicinal chemistry that also discusses avenues for the acceleration of drug discovery programs.

  • Purification of Laboratory Chemicals

    • 8th Edition
    • W.L.F. Armarego
    • English
    Purification of Laboratory Chemicals, Eighth Edition, tabulates methods taken from literature for purifying thousands of individual commercially available chemicals. To help in applying this information, the more common processes currently used for purification in chemical laboratories and new methods are discussed. For dealing with substances not separately listed, a chapter is included setting out the usual methods for purifying specific classes of compounds.

  • America Invents Act Primer

    • 1st Edition
    • Sarah Hasford
    • English
    Since its passage in 2011, the Leahy-Smith America Invents Act ("AIA") has brought many significant changes to U.S. patent law. Accordingly, to assist readers in developing an in-depth understanding of these changes, the America Invents Act Primer provides discussions of each and every one of the AIA’s substantive provisions. More specifically, and whenever possible, each discussion of the AIA’s provisions includes the following key features: An identification of the AIA section’s effective date, including the statutory basis for such dates; A direct comparison of relevant pre- and post-AIA statutes; An analysis of the similarities and differences between pre- and post-AIA statutes; A discussion of the legislative goals that were addressed by the AIA section; and An analysis of the practical implications of the changes made by the AIA section. The America Invents Act Primer additionally highlights a number of free resources that can be utilized by readers to attain a deeper understanding of the AIA, including resources that explain how the U.S. Patent and Trademark Office is applying the new law. Overall, the America Invents Act Primer provides a unique and practical desk reference on the AIA that is sure to be useful for years to come.

  • Metals in Mercury

    • 1st Edition
    • Volume 25
    • C. Hirayama + 2 more
    • English
    The volume covers binary amalgams of all the metals, together with those of carbon, silicon and boron, a total of 76 systems. Complete literature coverage extends through 1983. The emphasis is on accurate, evaluated solubility data, but phase diagrams have been included where they have been defined, and will aid the reader in assigning the solid-liquid equilibrium. Tha data have been critically evaluated, and are classified as 'recommended' when independent determinations agree within experimental error. The data may also be used to compute thermodynamic properties of the binary components.

  • The Application of Green Solvents in Separation Processes

    • 1st Edition
    • Francisco Pena-Pereira + 1 more
    • English
    The Application of Green Solvents in Separation Processes features a logical progression of a wide range of topics and methods, beginning with an overview of green solvents, covering everything from water and organic solvents, to ionic liquids, switchable solvents, eutectic mixtures, supercritical fluids, gas-expanded solvents, and more. In addition, the book outlines green extraction techniques, such as green membrane extraction, ultrasound-assisted extraction, and surfactant-mediated extraction techniques. Green sampling and sample preparation techniques are then explored, followed by green analytical separations, including green gas and liquid capillary chromatography, counter current chromatography, supercritical fluid chromatography, capillary electrophoresis, and other electrical separations. Applications of green chemistry techniques that are relevant for a broad range of scientific and technological areas are covered, including the benefits and challenges associated with their application.

  • Field Ionization Mass Spectrometry

    International Series of Monographs in Analytical Chemistry
    • 1st Edition
    • Hans-D. Beckey
    • R. Belcher + 1 more
    • English
    Field Ionization Mass Spectrometry focuses on developments in field ionization (FI) mass spectrometry and describes its applications in physical chemistry, with emphasis on mass spectrometric problems. Physico-chemical problems as well as problems of chemical analysis are considered based on issues such as the probability of field ionization; field dissociation and charge distribution; kinetics of ion decomposition in high fields; negative ions; surface diffusion; activation of FI emitters; and elucidation of the structures of organic compounds. This book is comprised of four chapters and begins with a short review on some of the most important directions of research in FI mass spectrometry. Two main fields of research are discussed: physico-chemical investigations and quantitative analysis or structural determination of organic substances. The next chapter is devoted to focusing and non-focusing sources of FI and covers topics such as methods for production of FI tips and thin wires, together with the use of tips and carbon filaments as FI emitters. The last two chapters focus on the application of the FI mass spectrometer to physico-chemical problems and to quantitative analysis of homologous series of organic substances such as alkanes, alkenes, alkynes, amines, and alcohols. This monograph is intended primarily for chemists and mass spectrometrists.

  • Membrane Characterization

    • 1st Edition
    • Nidal Hilal + 3 more
    • English
    Membrane Characterization provides a valuable source of information on how membranes are characterized, an extremely limited field that is confined to only brief descriptions in various technical papers available online. For the first time, readers will be able to understand the importance of membrane characterization, the techniques required, and the fundamental theory behind them. This book focuses on characterization techniques that are normally used for membranes prepared from polymeric, ceramic, and composite materials.

  • Polyoxometalate Chemistry

    • 1st Edition
    • Volume 69
    • English
    Polyoxometalate Chemistry continues a long-running series that describes recent advances in scientific research, in particular, in the field of inorganic chemistry. Several highly regarded experts, mostly from academia, contribute on specific topics. The current issue focuses on recent advances in the development and application of polyoxometalate complexes in areas such as solution chemistry, self-organization, solar fuels, non-aqueous chemistry, spintronics, nanoscience and catalysis.

  • Studies in Natural Products Chemistry

    • 1st Edition
    • Volume 52
    • Atta-ur Rahman
    • English
    Studies in Natural Products Chemistry covers the synthesis, testing, and recording of the medicinal properties of natural products, providing cutting-edge accounts of the fascinating developments in the isolation, structure elucidation, synthesis, biosynthesis, and pharmacology of a diverse array of bioactive natural products. Natural products in the plant and animal kingdom offer a huge diversity of chemical structures that are the result of biosynthetic processes that have been modulated over the millennia through genetic effects. With the rapid developments in spectroscopic techniques and accompanying advances in high-throughput screening techniques, it has become possible to isolate and then rapidly determine the structures and biological activity of natural products, thus opening up exciting opportunities in the field of new drug development in the pharmaceutical industry.

  • Supercritical Fluid Chromatography

    • 1st Edition
    • Colin F. Poole
    • English
    Supercritical fluid chromatography (SFC) is a rapidly developing laboratory technique for the separation and identification of compounds in mixtures. Significant improvements in instrumentation have rekindled interest in SFC in recent years and enhanced its standing in the scientific community. Many scientists are familiar with column liquid chromatography and its strengths and weaknesses, but the possibilities brought to the table by SFC are less well-known and are underappreciated. Supercritical Fluid Chromatography is a thorough and encompassing reference that defines the concept of contemporary practice in SFC and how it should be implemented in laboratory science. Given the changes that have taken place in SFC, this book presents contemporary aspects and applications of the technique and introduces SFC as a natural solution in the larger field of separation science. The focus on state-of-the-art instrumental SFC distinguishes this work as the go-to reference work for those interested in implementing the technique at an advanced level.

  • The Alkaloids

    • 1st Edition
    • Volume 77
    • English
    The Alkaloids, a series that has covered the topic for more than 60 years, is the leading book series in the field of alkaloid chemistry. In more than 70 volumes, all aspects of alkaloids—including their chemistry, biology, and pharmacology—are covered in high-quality, timeless reviews written by renowned experts in the field.

  • Advances in Clinical Chemistry

    • 1st Edition
    • Volume 79
    • English
    Advances in Clinical Chemistry, Volume 79 is the latest installment in this internationally acclaimed series and contains chapters authored by world-renowned clinical laboratory scientists, physicians, and research scientists. The serial discusses the latest and most up-to-date technologies related to the field of clinical chemistry and is the benchmark for novel analytical approaches in the clinical laboratory.

  • Modern Inorganic Synthetic Chemistry

    • 2nd Edition
    • Ruren Xu + 1 more
    • English
    Modern Inorganic Synthetic Chemistry, Second Edition captures, in five distinct sections, the latest advancements in inorganic synthetic chemistry, providing materials chemists, chemical engineers, and materials scientists with a valuable reference source to help them advance their research efforts and achieve breakthroughs. Section one includes six chapters centering on synthetic chemistry under specific conditions, such as high-temperature, low-temperature and cryogenic, hydrothermal and solvothermal, high-pressure, photochemical and fusion conditions. Section two focuses on the synthesis and related chemistry problems of highly distinct categories of inorganic compounds, including superheavy elements, coordination compounds and coordination polymers, cluster compounds, organometallic compounds, inorganic polymers, and nonstoichiometric compounds. Section three elaborates on the synthetic chemistry of five important classes of inorganic functional materials, namely, ordered porous materials, carbon materials, advanced ceramic materials, host-guest materials, and hierarchically structured materials. Section four consists of four chapters where the synthesis of functional inorganic aggregates is discussed, giving special attention to the growth of single crystals, assembly of nanomaterials, and preparation of amorphous materials and membranes. The new edition’s biggest highlight is Section five where the frontier in inorganic synthetic chemistry is reviewed by focusing on biomimetic synthesis and rationally designed synthesis.

  • Radioactive Investigations of Oil and Gas Wells

    A Textbook
    • 1st Edition
    • O. A. Barsukov + 2 more
    • English
    Radioactive Investigations of Oil and Gas Wells: A Textbook focuses on the radioactive methods used in the investigations of oil and gas wells, including radioactivity, nuclear reactions, and tracer method. The book first offers information on physical principles of the radiometry of wells and radioactive properties of rocks. Discussions focus on artificial transformation of elements and nuclear reactions; radioactivity and the law of radioactive disintegration; natural radioactivity; and induced radioactivity of rocks. The text then ponders on the methods of well geometry and radiometric apparatus. The publication examines the interpretation of results of measurements by the natural radioactivity method and working technique and interpretation of diagrams of the tracer method. Topics include selection of the radioactive isotope and technology of preparation of activated fluid and determination of absorbing strata and of communication between the strata outside the tubing in production wells and pressurized wells. The text is a dependable reference for readers interested in the radioactive methods used in the investigations of oil and gas wells.

  • Transition Metal-Catalyzed Benzofuran Synthesis

    Transition Metal-Catalyzed Heterocycle Synthesis Series
    • 1st Edition
    • Xiao-Feng Wu + 1 more
    • English
    Transition Metal-Catalyzed Benzofuran Synthesis: Transition Metal-Catalyzed Heterocycle Synthesis Series provides an overview of benzofuran, describing properties of these heterocycle compounds and the traditional synthetic procedures used for them. The book then explores catalyzed procedures for benzofuran synthesis in greater detail and depth than is currently available in published review articles. This volume is part of the short series authored by Xiao-Feng Wu that summarizes recent achievements on heterocycle synthesis with transition metals as catalysts, with each volume dedicated to one heterocycle compound.

  • Organometallic Chemistry

    Plenary Lectures Presented at the Eighth International Conference on Organometallic Chemistry, Kyoto, Japan, 12-16 September 1977
    • 1st Edition
    • Y. Ishii + 1 more
    • English
    Organometallic Chemistry — 8 focuses on the compositions, reactions, properties, and transformations of molecules, silicon carbon, molybdenum and tungsten compounds, palladium, and platinum. The selection first offers information on the theoretical aspects of the coordination of molecules to transition metal centers and generation and reactions of silicon-carbon double-bonded intermediates. Discussions focus on photolysis of naphthyldisilanes, alkenyldisilanes, phenylacetylene, and benzenoid aromatic derivatives of disilane. The book also considers classical and novel ylide systems in organometallic chemistry, including phosphorinanium and phospholanium ylides and organometallic compounds of double ylides. The text evaluates studies on the synthesis, mechanism, and reactivity of organo-molybdenum and tungsten compounds and enantioselective reactions through chiral metal-carbene intermediates. The manuscript also ponders on the synthesis and reactivity of carbon-bonded transition elements; neutron diffraction studies on transition metal hydride complexes; and applications of palladium in organic syntheses. The selection is an impressive reference for readers and chemists interested in organometallic chemistry.

  • The Chemistry of Ruthenium, Rhodium, Palladium, Osmium, Iridium and Platinum

    Pergamon Texts in Inorganic Chemistry, Volume 25
    • 1st Edition
    • Stanley E. Livingstone
    • English

  • Molecular Spectroscopy—XI

    Specially Invited Lectures Presented at the Eleventh European Congress on Molecular Spectroscopy
    • 1st Edition
    • O. Sild
    • English
    Molecular Spectroscopy–XI provides information pertinent to the fundamental aspects of molecular spectroscopy. This book discusses the modifications of molecular spectra when the density varies as a function of temperature and pressure. Organized into 15 chapters, this book begins with an overview of the several processes concerning triplet excitons leading to magnetic-field sensitive luminescence in organic crystals and related compounds. This text then examines the methods of investigation of the exciton band structures in molecular crystals. Other chapters consider the conditions for the equivalence of Fourier spectroscopy and of slow passage experiments in nuclear magnetic resonance. This book discusses as well the application of computer technology in carbon-13 magnetic resonance spectroscopy. The final chapter deals with the application of high-resolution proton and carbon-13 n.m.r. spectroscopy for the investigation of the molecular conformations in proteins. This book is a valuable resource for organic chemists, biologists, microbiologists, scientists, and research workers.

  • Organic Synthesis Today and Tomorrow

    Proceedings of the 3rd IUPAC Symposium on Organic Synthesis, Madison, Wisconsin, USA, 15-20 June 1980
    • 1st Edition
    • Barry M. Trost + 1 more
    • English
    Organic Synthesis: Today and Tomorrow covers the proceedings of the Third International Union of Pure and Applied Chemistry (IUPAC) Symposium on Organic Synthesis. The book covers topics that tackle relevant issues about organic chemistry. Comprised of 27 chapters, the book covers lectures that tackle topics pertaining organic chemistry. These topics include useful synthetic methods for general application; development of chemistry concepts for use in construction of molecular sub-assemblies; and interplay of synthetic methodology and the total synthesis of organic compounds. The book will be of great interest to scientists, such as biochemists who are concerned with the advances in organic chemistry.

  • Boron Chemistry – 4

    Plenary and Session Lectures Presented at the Fourth International Meeting on Boron Chemistry, Salt Lake City and Snowbird, Utah, USA, 9-13 July 1979
    • 1st Edition
    • Robert W. Parry + 1 more
    • English
    Boron Chemistry - 4 covers the proceedings of the Fourth International Meeting on Boron Chemistry. The book contains invited plenary lectures and session lectures given during the conference. The text discusses several topics concerning boron chemistry, such as conceptual advances in boron chemistry; cluster compounds and carboranes; and organometallic compounds containing boron ligands, boron clusters, or carboranes. This monograph also explains boranes as reagents in organic chemistry; organoboranes; chemistry of smaller boranes; and applications of the boranes. This book will be of great interest to researchers whose line of work involves a certain aspect of boron.

  • Chemistry for the Future

    Proceedings of the 29th IUPAC Congress, Cologne, Federal Republic of Germany, 5-10 June 1983
    • 1st Edition
    • H. Grünewald
    • English
    Chemistry for the Future covers the proceedings of the 29th IUPAC Congress on the Chemistry for the Future, held in Cologne, Federal Republic of Germany on June 5-10, 1983. The contributors consider the advances in inorganic, organic, physical, and theoretical chemistry. This book is organized into seven parts encompassing 59 chapters that also look into the progress in the production of chemical basic materials and education in chemistry. The opening parts survey the advances in complexation chemistry, photoelectrochemical energy conversion, biotechnology, and some aspects of inorganic chemistry. The succeeding part deals with the reactions, synthesis, and structure and properties determination of various organic compounds. Other parts evaluate the application of molecular quantum mechanics, laser studies, electrochemical energy conversion, microemulsion, adsorption, and progress in the production of chemical basic materials. The remaining parts explore the teaching of molecular geometry by the VSEPR method, the role of experiments in teaching chemistry, chemistry as a basis for the life sciences. These parts also examine the flow of information chemistry through databases, IUPAC, and chemical information services. This book will prove useful to organic, inorganic, physical, and theoretical chemists

  • Sources of Ignition

    Flammability Characteristics of Chemicals and Products
    • 1st Edition
    • John Bond
    • English
    Sources of Ignition: Flammability Characteristics of Chemicals and Products describes the flammability characteristics of substances and deals with the different sources of ignition. Case histories are presented for review and analysis. The book is comprised of six chapters and seven appendices. The introduction gives a basic description of the anatomy of fire and explosions, including the access to fuel and the interaction of oxygen and fuel. A description of the flammable limits of gases, dusts, mists, and mixtures and the method of estimating these follow. The text also explains the flash point of a substance and the method of calculating it, using citations from Fuji and Hermann. The ignition energy of a chemical, as well as how to estimate it using the method of Calcote et al., is also presented. The book explains that autoignition temperature of gases is dependent on different factors, such as time delay, oxygen concentration, and catalyst effects of materials, but may still be estimated citing Zabetakis, 1965 as reference. The formula is given in more detail. Finally, the energy sources for ignition are enumerated as mechanical, electrical, thermal, and chemical. The appendices deal with chemicals, self-heating substances, organic peroxides, substances prone to spontaneous combustions, unstable substances, flammability characteristics of dusts, and a checklist of possible sources of ignition. This book is beneficial to fire safety engineers, firemen, fire prevention maintenance administrators, fire hazard officers, and other personnel whose line of work is in fire safety and prevention.

  • Ion Beam Analysis

    Proceedings of the Fourth International Conference on Ion Beam Analysis, Aarhus, June 25-29, 1979
    • 1st Edition
    • H. H. Andersen + 2 more
    • English
    Nuclear Instruments and Methods, Volume 168: Ion Beam Analysis presents the proceedings of the Fourth International Conference on Ion Beam Analysis, held in Aarhus, Denmark, on June 25–29, 1979. This book provides information pertinent to the methods and applications ion beam analysis. Organized into eight parts encompassing 95 chapters, this volume begins with an overview of the straggling of energy loss for protons and alpha particles. This text then examines the method for the calculation of the stopping of energetic ions in matter. Other chapters consider the method for measuring relative stopping powers for light energetic ions in highly reactive materials. This book discusses as well the stopping power and straggling of lithium ions with velocities around the Bohr velocity. The final chapter deals with the adsorption behavior of different gases on monocrystalline platinum surfaces. This book is a valuable resource for scientists, technologists, students, and research workers.

  • Radiation Chemistry of Carbohydrates

    • 1st Edition
    • N. K. Kochetkov + 2 more
    • English
    Radiation Chemistry of Carbohydrates is a five-chapter book that deals with the detailed analysis of experimental data on the radiation chemistry of carbohydrates. After introducing the focus of the study, this book discusses the radiation chemistry of water and aqueous solutions. This discussion is followed by a topic on the general approaches and methods of investigation of the radiolysis of carbohydrates. This text also looks into the radiolysis of various classes of carbohydrates and into the major transformations of carbohydrates induced by irradiation. This book will be helpful for students and experts in the field of chemistry and related disciplines.

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