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Green Approaches in Medicinal Chemistry for Sustainable Drug Design

  • 2nd Edition
  • Volume 2
  • June 1, 2024
  • Bimal Banik
  • English
  • Paperback
    9 7 8 - 0 - 4 4 3 - 1 6 1 6 4 - 3
  • eBook
    9 7 8 - 0 - 4 4 3 - 1 6 1 6 5 - 0
Green Approaches in Medicinal Chemistry for Sustainable Drug Design: Methods, Second Edition reveals how medicinal chemistry can play a direct role in addressing this issue. After providing essential context on the growth of green chemistry in relation to drug discovery, the book identifies a range of practical techniques and useful insights, revealing how medicinal chemistry techniques can be used to improve efficiency, mitigate failure, and increase the environmental benignity of the entire drug discovery process. Drawing on the knowledge of a global experts, the book encourages the growth of green medicinal chemistry, and supports medicinal chemists, drug discovery researchers, pharmacologists, and more.This volume covers synthesis methods following green chemistry principles, contributing to sustainability by saving energy, using lesser toxic reagents/solvents/catalysts and environmentally benign sources, including plants and agricultural materials.

Green Approaches in Medicinal Chemistry for Sustainable Drug Design

  • 2nd Edition
  • Volume 1
  • May 30, 2024
  • Bimal Banik
  • English
  • Paperback
    9 7 8 - 0 - 4 4 3 - 1 6 1 6 6 - 7
  • eBook
    9 7 8 - 0 - 4 4 3 - 1 6 1 6 7 - 4
Sustainable and Green Approaches in Medicinal Chemistry: Applications, Second Edition reveals essential context on the growth of green chemistry in relation to drug discovery, identifying a broad range of practical techniques and useful insights and revealing how medicinal chemistry techniques can be used to improve efficiency, mitigate failure, and increase the environmental benignity of the entire drug discovery process. The book encourages the growth of green medicinal chemistry and supports medicinal chemists, drug discovery researchers, pharmacologists, and all those in related fields across both academia and industry in integrating these approaches into their own work.This volume includes the development of nanoparticles and nanocomposites, as well as the application of ultrasound and microwave-induced methods; studies solventless synthesis; defines the role of steroids; studies reactions in aqueous solution; identifies enzyme-mediated reactions; investigates ionic liquids and deep eutectic solvents; explores natural products; investigates solid supports; realizes the effects of salts; focuses on combinatorial chemistry; develops one-pot methods; analyzes multi-component reactions; investigates dipole moment values; and examines computer-assisted methods.

Advances in Heterocyclic Chemistry

  • 1st Edition
  • Volume 144
  • May 27, 2024
  • Eric F.V. Scriven + 1 more
  • English
  • Hardback
    9 7 8 - 0 - 4 4 3 - 2 9 7 4 2 - 7
  • eBook
    9 7 8 - 0 - 4 4 3 - 2 9 7 4 3 - 4
Advances in Heterocyclic Chemistry, Volume 144 highlights new advances in the field, with this volume presenting chapters on Metal free C-H functionalization of aromatic and non-aromatic heterocyclic systems, Divergent Total Synthesis of Indolizidine-, Quinolizidine-, and Decahydroquinoline-type Poison-frog Alkaloids, A perspective on the synthetic potential of bio-based building blocks for heterocyclic chemistry, Recent advances in the synthesis of 3,3-disubstituted oxetanes, and Pyrrole-based chemosensors: Recent trends.

The Alkaloids

  • 1st Edition
  • Volume 91
  • May 24, 2024
  • Hans-Joachim Knolker
  • English
  • Hardback
    9 7 8 - 0 - 4 4 3 - 2 9 5 5 4 - 6
  • eBook
    9 7 8 - 0 - 4 4 3 - 2 9 5 5 5 - 3
The Alkaloids: Chemistry and Biology, Volume 91, the newest release in a series that has covered the topic for more than 60 years, discusses key aspects of alkaloid chemistry, biology and pharmacology. Sections in this release include chapters on Recent Progress in the Chemistry of Naphthylisoquinoline Alkaloids.

Advances in Organometallic Chemistry

  • 1st Edition
  • Volume 81
  • May 22, 2024
  • Pedro J. Perez
  • English
  • Hardback
    9 7 8 - 0 - 4 4 3 - 2 9 4 2 0 - 4
  • eBook
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Advances in Organometallic Chemistry, Volume 81 in this ongoing series, highlights new advances in the field, with this new volume presenting interesting chapters written by an international board of authors. Specific chapters cover Recent Advances in the Catalytic Applications of NHC-Early Abundant Metals (Fe, Mn, Co) Complexes, A Guide to Non-Carbonyl, Non-Isocyano Organometallic Chemistry of Technetium-99 from Discovery to 2023, and Cyclopentadienyl, Amidinate (CPAM) Complexes of Groups 4 - 6 Transition Metals.

Studies in Natural Products Chemistry

  • 1st Edition
  • Volume 81
  • May 15, 2024
  • Atta-Ur Rahman
  • Atta-Ur Rahman
  • English
  • Hardback
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  • eBook
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Studies in Natural Products Chemistry, Volume 81 covers the synthesis or testing and recording of the medicinal properties of natural products, providing cutting-edge accounts on fascinating developments in the isolation, structure elucidation, synthesis, biosynthesis and pharmacology of a diverse array of bioactive natural products. Natural products in the plant and animal kingdom offer a huge diversity of chemical structures that are the result of biosynthetic processes that have been modulated over the millennia through genetic effects.With the rapid developments in spectroscopic techniques and accompanying advances in high-throughput screening techniques, it has become possible to isolate and then determine the structures and biological activity of natural products rapidly, thus opening up exciting opportunities in the field of new drug development to the pharmaceutical industry.

Recent Advances in Organometallic Chemistry

  • 1st Edition
  • April 10, 2024
  • Azaj Ansari + 1 more
  • English
  • Hardback
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  • eBook
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Recent Advances in Organometallic Chemistry: Synthetic, Mechanistic and Medicinal Perspective highlights recent advancements in the field of organometallic chemistry. Containing essential information for researchers and advanced-level students, especially those working in chemical synthesis, the book describes the role of organometallic compounds in different combinations in organic synthesis and pharmaceuticals as well as discussing spectral, magnetic and sensing features of the compounds. Including the role of computational investigations towards the mechanistic study of biomimic complexes in catalytic transformation reactions, the book provides a large number of examples along with their leading applications in other fields.Each chapter covers basic strategies, which are illustrated along with examples of the latest advancements in the field and in-depth explanations.

Organic Radicals

  • 1st Edition
  • March 14, 2024
  • Chuanyi Wang + 2 more
  • English
  • Paperback
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  • eBook
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Organic Radicals summarizes the applications of these materials in several fields, in addition to analyzing challenges, limitations and impacts of materials containing organic radicals on human, plants, water, soil, and animals. Sections cover uses of organic radicals as effective precursors for block molecules building and discuss their effectiveness as precursors of organic radical- containing materials synthesis and their applications in medicine, biology, electronics, environmental sciences, plastics synthesis, polymers building and the several impacts after organic radicals uses. In recent years, the rapid development of organic radical-containing materials has afforded an interesting research area in various applications.

Computational Phytochemistry

  • 2nd Edition
  • March 6, 2024
  • Satyajit Dey Sarker + 1 more
  • English
  • Paperback
    9 7 8 - 0 - 4 4 3 - 1 6 1 0 2 - 5
  • eBook
    9 7 8 - 0 - 4 4 3 - 1 6 1 0 3 - 2
Computational Phytochemistry, Second Edition, explores how recent advances in computational techniques and methods have been embraced by phytochemical researchers to enhance many of their operations, refocusing and expanding the possibilities of phytochemical studies. By applying computational aids and mathematical models to extraction, isolation, structure determination, and bioactivity testing, researchers can obtain highly detailed information about phytochemicals and optimize working approaches.This book aims to support and encourage researchers currently working with or looking to incorporate computational methods into their phytochemical work. Topics in this book include computational methods for predicting medicinal properties, optimizing extraction, isolating plant secondary metabolites, and building dereplicated phytochemical libraries. The roles of high-throughput screening, spectral data for structural prediction, plant metabolomics, and biosynthesis are all reviewed before the application of computational aids for assessing bioactivities and virtual screening is discussed. Illustrated with detailed figures and supported by practical examples, this book is an indispensable guide for all those involved with the identification, extraction, and application of active agents from natural products.This new edition captures remarkable advancements in mathematical modeling and computational methods that have been incorporated in phytochemical research, addressing, e.g., extraction, isolation, structure determination, and bioactivity testing of phytochemicals.

Glycosphingolipids in the Central Nervous System

  • 1st Edition
  • March 6, 2024
  • Zhongwu Guo
  • English
  • Paperback
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  • eBook
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Glycosphingolipids in the Central Nervous System: Diversity in Structure, Metabolism, Distribution, and Function comprehensively covers progress made in the discovery, profiling and understanding of the metabolism, function and functional mechanism of GSLs in the CNS –as well as their synthesis, relationships with and therapeutic applications to neurodegenerative disorders, and related CNS diseases. Due to the important roles of GSLs in the CNS and various CNS-related diseases, the interest in these biomolecules is growing. GSLs are the principal glycolipids on the cell surface and an essential constituent of the cell membrane. They are widespread, but especially enriched in the central nervous system (CNS) in vertebrates. The diversity of GSL structures forges the molecular foundation for their broad spectrum of activity.

Related subjects

Bioorganic chemistry

Carbohydrate chemistry

Combinatorial chemistry

Heterocyclic chemistry

Medicinal chemistry

Natural products chemistry

Organic synthesis

Pharmaceutical chemistry

Physical organic chemistry

Phytochemistry

Stereochemistry