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Rearrangements with Migration to Electrophilic Heteroatomic Centers
Timeless Classics in Organic Synthesis
- 1st Edition - October 1, 2024
- Author: Sosale Chandrasekhar
- Language: English
- Paperback ISBN:9 7 8 - 0 - 1 2 - 8 2 3 7 4 3 - 4
- eBook ISBN:9 7 8 - 0 - 1 2 - 8 2 3 7 4 4 - 1
Rearrangements with Migration to Electrophilic Heteroatomic Centers: Timeless Classics in Organic Synthesis covers the basic principles and synthetic applications of a critic… Read more
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Request a sales quoteRearrangements with Migration to Electrophilic Heteroatomic Centers: Timeless Classics in Organic Synthesis covers the basic principles and synthetic applications of a critically important class of organic reactions that date back to the founding period of organic chemistry. These reactions are not only of historical and pedagogical interest, but also have great practical value to this day, being inevitable in any strategy concerning the introduction of nitrogen and oxygen functionality. The book is made up of three parts, dealing with the Beckmann reaction, the Hoffmann family of reactions and the Baeyer-Villiger reaction.The book strikes a balance between delineation and exhaustiveness, with up-to-date refences for readers requiring in-depth coverage. Relevant industrial applications, including pharmaceutical processes, are included.
- Summarizes mechanistic background with an emphasis on synthetic applications
- Includes up-to-date references that allow for locating original papers for experimental procedures
- Provides applications in the synthesis of complex molecules and natural products to judge the scope and limitations of each reaction
Senior undergraduate students and researchers, including both academic and industrial researchers engaged in organic synthesis. Pharmaceutical chemists, particularly those engaged in process development
Part I. The Beckmann Rearrangement
Part II. The Hoffmann and Related Rearrangements
1. Introduction (historical and current status)
Mechanistic background
Reactions and Methodology
Scope and Applications
References
2. (Curtius) Introduction (historical and current status)
Mechanistic background
Reactions and Methodology
Scope and Applications
References
3. (Lossen) Introduction (historical and current status)
Mechanistic background
Reactions and Methodology
Scope and Applications
References
PART III. The Baeyer-Villiger Reaction
Introduction (historical and current status)
Mechanistic background
Reactions and Methodology
Scope and Applications
References
- No. of pages: 300
- Language: English
- Edition: 1
- Published: October 1, 2024
- Imprint: Elsevier
- Paperback ISBN: 9780128237434
SC
Sosale Chandrasekhar
Sosale Chandrasekhar was born on 25 April 1952; he earned his MSc from IIT Bombay, his PhD from the University of London, and his Postdoc from Cambridge University, Max-Planck Institute and Muelheim/Ruhr, University of Montreal. He taught at Indian Institute of Science Bangalore since 1984, and as Professor from 2003 onwards, and retired in 2017. His research interests include synthetic and mechanistic organic chemistry, stereochemistry and biological applications.
Affiliations and expertise
Professor, Department of Organic Chemistry, Indian Institute of Science, Bangalore, Karnataka, India