Synthesis of Epoxides
- 1st Edition - November 14, 2024
- Author: Navjeet Kaur
- Language: English
- Paperback ISBN:9 7 8 - 0 - 4 4 3 - 3 1 6 0 0 - 5
- eBook ISBN:9 7 8 - 0 - 4 4 3 - 3 1 6 0 1 - 2
Synthesis of Epoxides explores different techniques for making epoxides, both old and new, and delves into the growing field of heterocyclic chemistry. The book presents a variet… Read more
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Request a sales quoteSynthesis of Epoxides explores different techniques for making epoxides, both old and new, and delves into the growing field of heterocyclic chemistry. The book presents a variety of methods that will help readers figure out which one best suits their specific needs. Diazo compounds are important synthetic intermediates in organic synthesis, but because of their unpredictable, explosive nature and toxicity their unique reactivity has not been fully exploited and their use at large scale has been avoided. Readers, including students in chemistry, will learn about different methods and important information, allowing them to evaluate which method is most suitable in particular cases.
The synthetic usefulness of diazo compounds cannot be overlooked despite their danger. Because of their ylide and 1,3-dipole nature, the diazo compounds have a unique reactivity. The diazo compounds can be utilized for various different conversions including S-ylide-assisted epoxidation, cyclopropanation, or aziridination reactions. This book describes the new and classic methods for the synthesis of epoxides and covers an important and rapidly growing branch of heterocyclic chemistry.
The synthetic usefulness of diazo compounds cannot be overlooked despite their danger. Because of their ylide and 1,3-dipole nature, the diazo compounds have a unique reactivity. The diazo compounds can be utilized for various different conversions including S-ylide-assisted epoxidation, cyclopropanation, or aziridination reactions. This book describes the new and classic methods for the synthesis of epoxides and covers an important and rapidly growing branch of heterocyclic chemistry.
- Explores different ways of synthesizing epoxides
- Highlights the wide use of three-membered heterocyclic epoxides in pharmaceutical industry
- Includes centralized, comprehensive protocols for the synthesis of epoxides
Postgraduate students and researchers working with Organic Synthesis
- Title of Book
- Cover image
- Title page
- Table of Contents
- Copyright
- About the author
- Preface
- Abbreviations
- 1. Epoxide synthesis
- Abstract
- 1.1 Introduction
- 1.2 Synthesis of epoxides
- 1.3 Synthesis of epoxides from alkynes
- 1.4 Synthesis of epoxides from allenes
- 1.5 Synthesis of epoxides from oxaziridines
- References
- 2. Epoxide synthesis from alcohols
- Abstract
- 2.1 Introduction
- 2.2 Synthesis of epoxides from alcohols
- References
- 3. Epoxide synthesis from diazo compounds
- Abstract
- 3.1 Introduction
- 3.2 Synthesis of epoxides from diazo compounds
- 3.3 Synthesis of epoxides from diazomalonate
- 3.4 Synthesis of epoxides from diazomethane
- 3.5 Synthesis of epoxides from cyclic diazoamide
- 3.6 Synthesis of epoxides from phenyldiazoacetate
- 3.7 Synthesis of epoxides from phenyldiazomethane
- References
- 4. Epoxide synthesis from diols
- Abstract
- 4.1 Introduction
- 4.2 Synthesis of epoxides from diols
- 4.3 Synthesis of epoxides from diols using triphenylphosphine
- 4.4 Synthesis of epoxides from diols using sulfonyl chloride
- References
- 5. Epoxide synthesis from diols using sodium reagents
- Abstract
- 5.1 Introduction
- 5.2 Synthesis of epoxides from diols using sodium reagents
- References
- 6. Epoxide synthesis from haloalcohols
- Abstract
- 6.1 Introduction
- 6.2 Synthesis of epoxides from haloalcohols
- References
- 7. Epoxide synthesis from carbonyl compounds-I
- Abstract
- 7.1 Introduction
- 7.2 Synthesis of epoxides from carbonyl compounds
- 7.3 Synthesis of epoxides from two carbonyl compounds
- 7.4 Synthesis of epoxides from carbonyl compounds under phase-transfer conditions
- 7.5 Synthesis of epoxides from carbonyl compounds using alkynes
- References
- 8. Epoxide synthesis from carbonyl compounds-II
- Abstract
- 8.1 Introduction
- 8.2 Synthesis of epoxides from carbonyl compounds using lithium reagents
- 8.3 Synthesis of epoxides from carbonyl compounds using metals
- 8.4 Synthesis of epoxides from carbonyl compounds using sodium reagents
- 8.5 Synthesis of epoxides from carbonyl compounds using ylides
- References
- 9. Epoxide synthesis from carbonyl compounds using sulfur ylides-I
- Abstract
- 9.1 Introduction
- 9.2 Synthesis of epoxides from carbonyl compounds using sulfur ylides
- 9.3 Synthesis of epoxides from carbonyl compounds using methylsulfonium salt
- 9.4 Synthesis of epoxides from carbonyl compounds using sulfoxonium ylides
- References
- 10. Epoxide synthesis from carbonyl compounds using sulfur ylides-II
- Abstract
- 10.1 Introduction
- 10.2 Synthesis of epoxides from carbonyl compounds using camphor-derived sulfonium salts
- 10.3 Synthesis of epoxides from carbonyl compounds using chiral 1,3-oxathiane-derived sulfonium ylides
- 10.4 Synthesis of epoxides from carbonyl compounds using other heterocycle-derived sulfonium ylides
- References
- 11. Epoxide synthesis from carbonyl and halo compounds
- Abstract
- 11.1 Introduction
- 11.2 Synthesis of epoxides from carbonyl and halo compounds
- 11.3 Synthesis of epoxides from carbonyl and halo compounds using crown ethers
- 11.4 Synthesis of epoxides from carbonyl and halo compounds using phase-transfer catalysts
- References
- 12. Epoxide synthesis from carbonyl and halo compounds using sulfides
- Abstract
- 12.1 Introduction
- 12.2 Synthesis of epoxides from carbonyl and halo compounds using sulfides
- References
- Index
- No. of pages: 352
- Language: English
- Edition: 1
- Published: November 14, 2024
- Imprint: Elsevier
- Paperback ISBN: 9780443316005
- eBook ISBN: 9780443316012
NK
Navjeet Kaur
Dr. Navjeet Kaur received her BSc from Panjab University Chandigarh (Panjab, India) in 2008. In 2010, she completed her MSc in Chemistry from Banasthali Vidyapith. She was awarded with PhD in 2014 by the same university. With 11 years of teaching experience, she has published over 160 scientific research papers, review articles, book chapters, and monographs in the field of organic synthesis in national and international reputed journals. She has published five authored books: with Elsevier. She secured her place amongst top 2% scientists of the world in 2017 (single year ranking), 2018 (full career wise ranking), 2019 [full career wise ranking with 424 world rank (04 in India) and single year ranking with 03 world rank (01 in India)] and 2020 (full career wise ranking with 372 world rank and single year ranking with 126 world rank). In 2021, Dr. Kaur was chosen as a candidate for membership by Royal Society of Research, London, England, UK with full waiver of application fees. She is serving as an Editor-in-Chief of the “Advanced Chemicobiology Research” journal.
Affiliations and expertise
Lovely Professional University, India