Books in Life sciences

Systems Biology Approaches for Host-Pathogen Interaction Analysis

1st Edition
February 12, 2024
Mohd. Tashfeen Ashraf + 2 more
English
Paperback
9 7 8 0 3 2 3 9 5 8 9 0 5
eBook
9 7 8 0 3 2 3 9 5 8 9 1 2

Application and utilization of data science approaches has revolutionized scientific research including host–pathogen interaction analyses. Host–pathogen interactions are generally considered highly specific interactions, resulting in a variety of consequences. Data science approaches coupled with network biology has taken host–pathogen interaction analysis from specific interaction to a new paradigm of understanding the consequences of these interactions within a biological network. Unfortunately, basic biological researchers are mostly unaware of these advancements. Conversely, data scientists are not familiar with biological aspects of such data.Systems Biology Approaches for Host–Pathogen Interaction Analyses benefits biological researchers by expanding the scope of their research and utilization of their accumulated data using recent technological advancements. In addition, the book also opens avenues for bioinformatics and computer science researchers to utilize their expertise in biologically meaningful ways.

Rare and Complex Urology

1st Edition
February 12, 2024
Jen Tidman + 1 more
English
Paperback
9 7 8 0 3 2 3 9 9 9 3 4 2
eBook
9 7 8 0 3 2 3 9 9 9 3 5 9

Rare and Complex Urology has been produced by the European Reference Network (ERN) for rare urogenital diseases and complex conditions, ERN eUROGEN.The book combines information on network developments and clinical and surgical aspects, allowing for better diagnoses, treatments, and patient outcomes.The expertise areas covered include those relating to the bladder, stone and kidney diseases, congenital malformations, pelvic floor disorders, the urethra, reconstruction, and rare cancers and tumours.This is a must-have reference for clinicians and basic scientists interested in translational urology and surgery, including urologists, paediatric surgeons, and multidisciplinary team members seeking guidance on how to implement novel research.

DNA Damage and Chromosomal Instability

1st Edition
Volume 182
February 12, 2024
Christian Zierhut + 1 more
English
Hardback
9 7 8 0 4 4 3 1 8 8 9 8 5
eBook
9 7 8 0 4 4 3 1 8 8 9 9 2

DNA Damage and Chromosomal Instability, Volume 182 in the Methods in Cell Biology series, presents interesting chapters on a variety of timely topics, including Induction of chromosome-specific micronuclei and chromothripsis by centromere inactivation, Generation of aneuploid cells and assessment of their ability to survive in presence of chemotherapeutic agents, Genetic reporters to detect and quantify homologous recombination in yeast, Mapping histone variant genomic distribution: exploiting SNAP- Tag labelling to follow the dynamics of incorporation of H3 variants, Enrichment of DNA replication intermediates by EdU pull down, Nascent DNA sequencing and its diverse applications in genome integrity research, and much more. Additional chapters cover Enrichment of DNA replication intermediates by EdU pull down, DNA curtains for studying phase separation mechanisms of DNA-organizing proteins, Visualizing the Dynamics of DNA Replication and Repair at the Single-Molecule Molecule Level, Cloning and Expansion of Repetitive DNA Sequences, Using an ImageJ-based script to detect replication stress and associated cell cycle exit from G2 phase by fluorescence microscopy Arne Lindqvist

A Comprehensive Guide to Toxicology in Nonclinical Drug Development

3rd Edition
February 11, 2024
Ali S. Faqi
English
Hardback
9 7 8 0 3 2 3 8 5 7 0 4 8
eBook
9 7 8 0 3 2 3 9 8 4 6 2 1

**Selected for 2025 Doody’s Core Titles® in Toxicology**A Comprehensive Guide to Toxicology in Nonclinical Drug Development, Third Edition is a valuable reference providing a complete understanding of all aspects of nonclinical toxicology in pharmaceutical research. This updated edition has been expanded and re-developed covering a wide-range of toxicological issues in small molecules and biologics. Topics include ADME in drug discovery, pharmacokinetics, toxicokinetics, formulations, and genetic toxicology testing. The book has been thoroughly updated throughout to reflect the latest scientific advances and includes new information on antiviral drugs, anti-diabetic drugs, immunotherapy, and a discussion on post-pandemic drug development challenges and opportunities. This is an essential and practical resource for all toxicologists involved in nonclinical testing in industry, academic, and regulatory settings.

Dysphagia

1st Edition
February 9, 2024
Michael B. Ujiki + 1 more
English
Paperback
9 7 8 0 4 4 3 1 9 0 6 3 6
eBook
9 7 8 0 4 4 3 1 9 0 6 4 3

Dysphagia: A Clinical Guide will help practitioners and surgeons learn and understand how best to diagnose and treat dysphagia. It provides a complete picture of dysphagia through the experiences of leaders who cover the latest techniques and evidence-based outcomes in the field. Coverage includes recent advances in the diagnosis and treatment of the disease processes that cause dysphagia, gastric problems, and surgical intervention. The book includes the latest research and perspectives from both gastroenterologists and surgeons to enable clinicians to stay up-to-date on the most current and effective management strategies. Each chapter provides summary statements and recommendations based on recent literature.Recent discoveries regarding the diagnosis and management of dysphagia are exemplified by illustrations of both diagnostic methods and descriptions of interventional techniques. This an important reference for general surgeons, general practitioners, and ENT surgeons while also bringing new data dedicated specifically to gastroenterologists and foregut surgeons.

Huntington’s Disease

1st Edition
February 7, 2024
X. William Yang + 2 more
English
Paperback
9 7 8 0 3 2 3 9 5 6 7 2 7
eBook
9 7 8 0 3 2 3 9 5 6 7 3 4

Huntington's disease (HD) is one of the most common dominantly inherited neurodegenerative disorders, characterized by a clinical triad of movement disorder, cognitive deficits, and psychiatric symptoms. Huntington’s Disease: Pathogenic Mechanisms and Implications for Therapeutics reviews the most up-do-date content on HD pathogenic mechanisms and cutting-edge thinking on therapeutic strategies for HD. Chapters explore areas that include the clinical features and genetic studies of HD, the cellular and molecular biology of normal huntingtin, a range of HD models, the diverse pathogenic mechanisms linked to mutant huntingtin, new approaches to HD pathogenesis, as well as emerging preclinical therapeutic approaches and clinical programs in the field.

Translational Approaches to Unravelling Non-Motor Symptoms of Parkinson’s disease

1st Edition
Volume 174
February 7, 2024
Mahmoud Iravani + 1 more
English
Hardback
9 7 8 0 3 2 3 9 9 1 8 3 4
eBook
9 7 8 0 3 2 3 9 9 1 8 4 1

Translational Approaches to Non-Motor Symptoms of Neurodegenerative Diseases, Volume 173 in the International Review on Neurobiology series, highlights new advances in the field with this new volume presenting interesting chapters on topics such as A general clinical overview of the non-motor symptoms, Stress/fatigue/cogni... decline Sleep/autonomic failure, A general clinical overview of the non-motor symptoms – psychiatric symptoms, Psychosis, Cognitive Decline, Non-clinical Aspect of non-motor symptoms: Animal Models, Assessment and treatment of cognitive decline in rodent and primate models, Pain in PD models, Affective disorders in PD models, Sleep and circadian dysregulation and EEG disruption in rodent models, and much more.

The Neuroscience of Bach’s Music

1st Edition
February 7, 2024
Eric Altschuler
English
Paperback
9 7 8 0 4 4 3 1 3 5 1 9 4
eBook
9 7 8 0 4 4 3 1 3 5 2 0 0

The Neuroscience of Bach’s Music: Perception, Action, and Cognition Effects on the Brain is a comprehensive study of Johann Sebastian Bach’s music through the lens of neuroscience, examining neuroscience using Bach’s music as a tool. This book synthesizes cognitive neuroscience, music theory, and musicology to provide insights into human cognition and perception. It also explores how a neuroscience perspective can improve listening and performing experiences for Bach’s music. Written by a physician-neuroscien... recognized for scholarly articles on Bach’s music, this book uses specific examples to explore neuroscience across Bach’s compositions.The book is structured to discuss the brain’s action, perception, and cognition as connected to specific Bach concertos, tones, notes, and performances. Two guest contributors provide insight into exact mathematical, or topologic, and music theoretic aspects of Bach’s music with implications for cognitive neuroscience.

Advances in Agronomy

1st Edition
Volume 184
February 7, 2024
Donald L. Sparks
English
Hardback
9 7 8 0 4 4 3 2 9 5 2 4 9
eBook
9 7 8 0 4 4 3 2 9 5 2 5 6

Advances in Agronomy, Volume 184, the latest release in this leading reference on agronomy, contains a variety of updates and highlights new advances in the field. Each chapter is written by an international board of authors, with this new release including new chapters on The Role of Artificial Intelligence in Crop Improvement, Dealing with the Impact of Climate Change-Induced Drought on the Management of Soil, Challenges and Emerging Opportunities of Weed Management in Organic Agriculture, The Broadbalk Wheat Experiment, Rothamsted, UK: Crop Yields and Soil Changes During the Last 50 Years.

Many-Sorted Algebras for Deep Learning and Quantum Technology

1st Edition
February 3, 2024
Charles R. Giardina
English
Paperback
9 7 8 0 4 4 3 1 3 6 9 7 9
eBook
9 7 8 0 4 4 3 1 3 6 9 8 6

Many-Sorted Algebras for Deep Learning and Quantum Technology presents a precise and rigorousdescription of basic concepts in quantum technologies and how they relate to deep learning and quantum theory. Current merging of quantum theory and deep learning techniques provides the need for a source that gives readers insights into the algebraic underpinnings of these disciplines. Although analytical, topological, probabilistic, as well as geometrical concepts are employed in many of these areas, algebra exhibits the principal thread; hence, this thread is exposed using many-sorted algebras. This book includes hundreds of well-designed examples that illustrate the intriguing concepts in quantum systems. Along with these examples are numerous visual displays. In particular, the polyadic graph shows the types or sorts of objects used in quantum or deep learning. It also illustrates all the inter and intra-sort operations needed in describing algebras. In brief, it provides the closure conditions. Throughout the book, all laws or equational identities needed in specifying an algebraic structure are precisely described.

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