Introduction to Enzymology

PrefaceI. IntroductionII. Hydrolysis of Peptides and ProteinsIII. Fermentation and Oxidation of Major Metabolic Fuels Glycolysis Pyruvate Oxidation and Acetyl Coenzyme A Formation Free Energy and the Concept of Bond Energy Reactions of Coenzyme A The Krebs Citric Acid Cycle Alternative Pathways of Carbohydrate Metabolism Oxidation of Fatty AcidsIV. Biological Oxidation: Tranfer of Oxygen, Hydrogen, and Electrons Pyridine Nucleotides Oxidation-Reduction Potentials Flavoproteins Cytochromes The Hydroperoxidases: Catalase and Peroxidase Oxidases and OxygenasesV. Sugars and Sugar Derivatives Polysaccharides Reactions of Uridine NucleotidesVI. Polynucleotides and their Components Nucleic Acids Purines and PyrimidinesVII. Amino Acids Amino Acid Decarboxylases Transamination Oxidation of Amino Acids Glutamic Acid and Amino Acids Derived from It Aspartic Acid, Threonine, and Lysine The Urea Cycle β-Hydroxy-α-amino Acids Metabolism of Sulfur-Containing Amino Acids Histidine Aromatic Ring Biosynthesis and Metabolism of Phenylalanine and Tyrosine Tryptophan Mechanism of Action of Pyridoxal Phosphate Enzymes Metabolism of AminesVIII. Acids and Acid Derivatives Esters Carbonic AnhydraseIX. Organization of Structure and Function Integration of Biochemical Reactions Adaptive Enzymes and the Synthesis of ProteinsAppendix: AbbreviationsSubject Index