Limited Offer
Structure–Function Relationships of Proteolytic Enzymes
Proceedings of the International Symposium, Copenhagen June 16-18, 1969, No. 37 in the Series of the International Union of Biochemistry Sponsored Symposia
- 1st Edition - May 10, 2014
- Editors: P. Desnuelle, H. Neurath, M. Ottesen
- Language: English
- Paperback ISBN:9 7 8 - 1 - 4 8 3 2 - 3 8 1 0 - 4
- eBook ISBN:9 7 8 - 1 - 4 8 3 2 - 6 1 1 7 - 1
Structure–Function Relationships of Proteolytic Enzymes provides information pertinent to the fundamental aspects of proteolytic enzymes. This book presents the historical role of… Read more
Purchase options
Institutional subscription on ScienceDirect
Request a sales quoteStructure–Function Relationships of Proteolytic Enzymes provides information pertinent to the fundamental aspects of proteolytic enzymes. This book presents the historical role of proteolytic enzyme as a group in protein and enzyme chemistry. Organized into 23 chapters, this book begins with an overview of the results obtained from investigation on the chymotrypsinogens of porcine origin. This text then examines the differences of amino acid sequence between chymotrypsin, trypsin, and elastase that affect the substrate binding site, which reflect the specificity differences between these enzymes. Other chapters consider the kinetic parameters related to the trypsin-catalyzed hydrolysis of several model peptides. This book discusses as well the acetylation of trypsin, which result in functional consequences varying from complete inactivation to promotion of activity. The final chapter deals with the physical properties of stem bromelain in comparison with the data for three other sulfhydryl proteases of plant origin. This book is a valuable resource for enzymologists, microbiologists, and biochemists.
List of Participants
Foreword
Session I: Pancreatic Proteases
On the Three Chymotrypsinogens of Porcine Pancreas
Comments
Comments
Chymotrypsin: Tertiary Structure and Enzymatic Activity (Abstract)
Comments
Comments
The Role of Carboxylates and Phenol Side-Chains in the Activity and Conformation of Trypsinogen, Trypsin, Chymotrypsinogen, and Chymotrypsin
Chemical Modifications of Bovine Trypsinogen and Trypsin
The Specificity Site of Trypsin
Comments
Structure and Mechanism of Action of a Pancreatic Trypsin Inhibitor
The Chemistry of the Reactive Site of Soybean Trypsin Inhibitor
Structural Aspects of Interaction of Trypsin with Macromolecular Inhibitors
Homology and Phylogeny of Proteolytic Enzymes
Comments
Comments
Structural Aspects of Thrombin and Prothrombin
Cobalt Proteases: Implications of Absorption and Circular Dichroism Spectra for Catalysis
Session II: Microbial Proteases
Some Structure-Function Relationships in the Subtilisins
Subtilisin BPN': Tertiary Structure and Inhibitor Binding (Abstract)
Comments
Subtilisin: Stability Properties and Secondary Binding Sites
Comments
Aminopeptidases from Thermophilic Microorganisms
The Second Kaj Linderstrom-Lang Gold Medal Lecture
A Synthetic Approach to the Study of Microenvironmental Effects on Enzyme Action
Session III: Pepsin and Related Enzymes
Specificity and Mechanism of Pepsin Action
Comments
Towards a Mechanism for Pepsin
Comments
Comments
Chemical Studies on Purified Pepsin
Porcine Pepsinogen and Pepsin
Comments
Session IV: Sulfhydryl Proteases
The Three-Dimensional Structure of Papain
Streptococcal Proteinase
Structure and Function of Stem Bromelain
- No. of pages: 310
- Language: English
- Edition: 1
- Published: May 10, 2014
- Imprint: Academic Press
- Paperback ISBN: 9781483238104
- eBook ISBN: 9781483261171