Mechanisms in Bioenergetics

PrefaceAbbreviationsReference AbbreviationsPart I Formation of Adenosine Triphosphate in Soluble Systems Lecture 1 General Considerations of Energy Production Substrate Level Oxidative Phosphorylation Phosphoroclastic Reactions Dehydration of 2-Phosphoglycerate Catalyzed by Enolase Oxidative Phosphorylation and Photophosphorylation Lecture 2 Substrate Level Oxidative Phosphorylation (A) Oxidation of Glyceraldehyde 3-Phosphate Lecture 3 Substrate Level Oxidative Phosphorylation (B) Oxidation of Glyceraldehyde 3-Phosphate Lecture 4 Substrate Level Oxidative Phosphorylation (C) Oxidation of Acetaldehyde in Bacteria Aspartic Semialdehyde Dehydrogenase Oxidation of α-Ketoglutarate and Pyruvate Other Variants Lecture 5 Phosphoroclastic Reactions: Phosphoketolase Phosphoketolase Lecture 6 Other Phosphoroclastic Reactions Reactions with Pyruvate Phosphorolysis of a C—N Bond Phosphorolysis of Thiol Esters Dehydration of 2-Phosphoglycerate Catalyzed by EnolasePart II Formation of Adenosine Triphosphate in Particulate Systems Lecture 7 Oxidative Phosphorylation in Mitochondria Stages of Discovery Mitochondrial Enzymes Lecture 8 The Respiratory Chain Cytochromes 𝒂 and 𝒂3 Cytochrome 𝒄 Cytochrome 𝒄1 Cytochrome 𝒃 Flavoproteins Pyridine Nucleotides Ubiquinone-Coenzyme 𝑄 Phospholipids Structural Protein Electron Carriers Lecture 9 Localization of Phosphorylation Sites in Mitochondria The Crossover Point Measurements of the Three Phosphorylation Sites Thermodynamic Considerations Lecture 10 Exchange Reactions in Oxidative Phosphorylation The Pi32-ATP Exchange Quantitative Evaluation The ADP-ATP Exchange The H2O18-Pi and H2O18-ATP Exchanges Lecture 11 Partial Reactions of Oxidative Phosphorylation ATPase Reversal of Electron Transport Lecture 12 Uncouplers and Inhibitors of Oxidative Phosphorylation True Uncouplers of Oxidative Phosphorylation Inhibitory Uncouplers Inhibitors of Oxidative Phosphorylation Inhibitors of Oxidation Lecture 13 Soluble Factors and Intermediates of Oxidative Phosphorylation Nonprotein Factors Protein Coupling Factors Lecture 14 Theories and Speculations TextPart III Regulation of Adenosine Triphosphate Utilization in Multi-Enzyme Systems Lecture 15 Studies of Reconstructed Multi-Enzyme Systems Text Lecture 16 Approaches to The Metabolism of Intact Cells and to The Rate-Limiting Factors in Ascites Tumor Cells Rate-Limiting Factors in Ascites Tumor Cells Lecture 17 Metabolism of Intact Cells Rate-Limiting Factors in HeLa Cells Rate-Limiting Factors in Leukocytes and Brain Rate-Limiting Factors in Muscle Lecture 18 Induced Changes in Energy Metabolism TextSubject Index