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Elsevier

Books in Neuroscience

Elsevier's Neuroscience collection empowers educators, researchers, and students with actionable knowledge to drive collaborative research and advancements in the field. Content covers the nervous system's intricate workings, covering branches like Affective, Behavioral, and Cognitive neuroscience to investigate the neural basis of emotions, behavior, and cognitive functions. Spanning from Molecular and Cellular Neuroscience to Developmental Neuroscience, content provides insights into brain function in health and disease.

  • Puzzling Cases of Epilepsy

    • 2nd Edition
    • Dieter Schmidt + 1 more
    • English
    Epilepsy is one of the most common neurological disorders, and original observations in the field are often the key to diagnosis and successful treatment. Physicians new to the field as well as seasoned practitioners will benefit from more than one hundred case vignettes that explore the universe of epilepsy as it presents in daily practice. Some of these cases challenge long-held views about epilepsy and others bring the reader to the limits of our understanding of epilepsy, both in clinical and basic science. To improve the interface of clinical and basic science in epilepsy, basic scientists comment on the potential mechanisms underlying clinical observations, and clinicians assess the potential impact of recent results of experiments in the laboratory. Puzzling Cases of Epilepsy highlights the importance that original observations have in inspiring both new treatments and continued research.

  • The Prefrontal Cortex

    • 4th Edition
    • Joaquin Fuster
    • Joaquin Fuster
    • English
    This is the fourth edition of the undisputed classic on the prefrontal cortex, the principal "executive" structure of the brain. Because of its role in such cognitive functions as working memory, planning, and decision-making, the prefrontal cortex is critically involved in the organization of behavior, language, and reasoning. Prefrontal dysfunction lies at the foundation of several psychotic and neurodegenerative disorders, including schizophrenia and dementia.

  • Using Eye Movements as an Experimental Probe of Brain Function

    A Symposium in Honor of Jean Büttner-Ennever
    • 1st Edition
    • Volume 171
    • R. John Leigh + 1 more
    • English
    This volume of Progress in Brain Research is based on the proceedings of a conference, "Using Eye Movements as an Experimental Probe of Brain Function," held at the Charing Cross Hospital Campus of Imperial College London, UK on 5th -6th December, 2007 to honor Professor Jean Büttner-Ennever. With 87 contributions from international experts – both basic scientists and clinicians – the volume provides many examples of how eye movements can be used to address a broad range of research questions. Section 1 focuses on extraocular muscle, highlighting new concepts of proprioceptive control that involve even the cerebral cortex. Section 2 comprises structural, physiological, pharmacological, and computational aspects of brainstem mechanisms, and illustrates implications for disorders as diverse as opsoclonus, and congenital scoliosis with gaze palsy. Section 3 addresses how the cerebellum transforms neural signals into motor commands, and how disease of such mechanisms may lead to ataxia and disorders such as oculopalatal tremor. Section 4 deals with sensory-motor processing of visual, vestibular, somatosensory, and auditory inputs, such as are required for navigation, and gait. Section 5 illustrates how eye movements, used in conjunction with single-unit electrophysiology, functional imaging, transcranial magnetic stimulation, and lesion studies have illuminated cognitive processes, including memory, prediction, and even free will. Section 6 includes 18 papers dealing with disorders ranging from congenital to acquired forms of nystagmus, genetic and degenerative neurological disorders, and treatments for nystagmus and motion sickness.

  • Advances in the Study of Behavior

    • 1st Edition
    • Volume 38
    • H. Jane Brockmann + 5 more
    • English
    Advances in the Study of Behavior was initiated over 40 years ago to serve the increasing number of scientists engaged in the study of animal behavior. That number is still expanding. This volume makes another important "contribution to the development of the field" by presenting theoretical ideas and research to those studying animal behavior and to their colleagues in neighboring fields. Advances in the Study of Behavior is now available online at ScienceDirect — full-text online from volume 30 onward.

  • Human Learning: Biology, Brain, and Neuroscience

    • 1st Edition
    • Volume 139
    • Aaron S. Benjamin + 3 more
    • English
    Human learning is studied in a variety of ways. Motor learning is often studied separately from verbal learning. Studies may delve into anatomy vs function, may view behavioral outcomes or look discretely at the molecular and cellular level of learning. All have merit but they are dispersed across a wide literature and rarely are the findings integrated and synthesized in a meaningful way. Human Learning: Biology, Brain, and Neuroscience synthesizes findings across these levels and types of learning and memory investigation.Divide... into three sections, each section includes a discussion by the editors integrating themes and ideas that emerge across the chapters within each section. Section 1 discusses general topics in human learning and cognition research, including inhibition, short term and long term memory, verbal memory, memory disruption, and scheduling and learning. Section 2 discusses cognitive neuroscience aspects of human learning. Coverage here includes models, skill acquisition, declarative and non declarative memory, age effects on memory, and memory for emotional events. Section 3 focuses on human motor learning.This book is suitable for cognitive neuroscientists, cognitive psychologists, kinesthesiologists, and graduate courses in learning.

  • Handbook of Cognitive Science

    An Embodied Approach
    • 1st Edition
    • Paco Calvo + 1 more
    • English
    The Handbook of Cognitive Science provides an overview of recent developments in cognition research, relying upon non-classical approaches. Cognition is explained as the continuous interplay between brain, body, and environment, without relying on classical notions of computations and representation to explain cognition. The handbook serves as a valuable companion for readers interested in foundational aspects of cognitive science, and neuroscience and the philosophy of mind. The handbook begins with an introduction to embodied cognitive science, and then breaks up the chapters into separate sections on conceptual issues, formal approaches, embodiment in perception and action, embodiment from an artificial perspective, embodied meaning, and emotion and consciousness. Contributors to the book represent research overviews from around the globe including the US, UK, Spain, Germany, Switzerland, France, Sweden, and the Netherlands.

  • Animal Models in Eye Research

    • 1st Edition
    • Panagiotis Antonios Tsonis
    • English
    The eye is a complex sensory organ, which enables visual perception of the world. Thus the eye has several tissues that do different tasks. One of the most basic aspects of eye function is the sensitivity of cells to light and its transduction though the optic nerve to the brain. Different organisms use different ways to achieve these tasks. In this sense, eye function becomes a very important evolutionary aspect as well. This book presents the different animal models that are commonly used for eye research and their uniqueness in evaluating different aspects of eye development, evolution, physiology and disease.

  • Advances in Vasopressin and Oxytocin - From Genes to Behaviour to Disease

    • 1st Edition
    • Volume 170
    • Rainer Landgraf + 1 more
    • English
    Vasopressin and oxytocin are the key hormones of the hypothalamo-neurohyp... system, and are well-known to be critically involved in antidiuresis, labor, and milk ejection. This book highlights the latest research on vasopressin and oxytocin, covering multiple biological aspects. The capacity of both hormones to regulate various aspects of social behaviours including pair-bonding, aggression, maternal love, and sexual behaviour, is a main focus, as are their interactions with a variety of other neuromodulators and transmitters. Moreover, the book illustrates the recent development of vasopressin and oxytocin agonists/antagonists as potential drugs to treat not only disturbances of body fluid homeostasis, but also mental disorders, including social phobia, autism, anxiety, and depression. The promising combination of basic and clinical research, comprising physiology, neuroendocrinology, behavioral biology, pharmacology, imaging and molecular genetics makes this book an essential addition to both experts and scientists new to the field alike.

  • Mathematical Difficulties

    Psychology and Intervention
    • 1st Edition
    • English
    This book examines the mathematical difficulties in typical and atypical populations. It discusses the behavioural, educational and neuropsychological characteristics of people with mathematical difficulties, and educational interventions to prevent, diagnose, treat or ameliorate such difficulties. The book brings together studies from different disciplines, including developmental psychology, neuroscience and education, and includes perspectives from practicing teachers.The book is divided into three major sections. The first includes chapters about the nature and characteristics of mathematical difficulties in the population as a whole, in relation to both psychology and education. The second deals with mathematical difficulties in children with other problems such as specific language impairment and dyslexia. The third discusses methods of interventions aimed at preventing, treating or ameliorating mathematical difficulties, and will include discussions of assessment and diagnosis.

  • Disorders of Consciousness

    • 1st Edition
    • Volume 90
    • G. Bryan Young + 1 more
    • English
    This volume encompasses a variety of topics pertaining to patients with altered levels of consciousness, including valuable differences between disorders. Neurologists, researchers, and clinicians will find a comprehensive accounting of the distinctions between disorders that cause these altered states. Beginning with basic concepts of consciousness and neurobiology, this handbook progresses into more targeted and complex areas of discussion, including important technological advancements that have occurred in neuroimaging. Neurologists who are frequently called upon for prognostication and to guide management of patients with these disorders will find invaluable information, including chapters discussing comatose states in children and pregnant women, encephalopathic patients, nutrition disorders, and vegetative and minimally conscious states. In addition, chapters devoted to philosophical backgrounds and ethical implications involving patients with impaired consciousness, are thoroughly presented.

  • The Psychology of Learning and Motivation

    Advances in Research and Theory
    • 1st Edition
    • Volume 49
    • English
    The Psychology of Learning and Motivation publishes empirical and theoretical contributions in cognitive and experimental psychology, ranging from classical and instrumental conditioning to complex learning and problem solving. Volume 49 contains chapters on short-term memory, theory and measurement of working memory capacity limits, development of perceptual grouping in infancy, co-constructing conceptual domains through family conversations and activities, the concrete substrates of abstract rule use, ambiguity, accessibility, and a division of labor for communicative success, and lexical expertise and reading skill.

  • Neurologie du comportement

    La dimension neurologique de la neuropsychologie
    • 1st Edition
    • Armin Schnider
    • French
    À la confluence de la neurologie, de la neuropsychologie et de la psychiatrie, la neurologie comportementale est une spécialité qui s'intéresse aux troubles cognitifs, émotionnels et comportementaux dus à des atteintes cérébrales. Elle explore les mécanismes, la base anatomique et les étiologies des dysfonctionnements des fonctions supérieures du cerveau, telles que la mémoire, le langage, la pensée spatiale et le raisonnement. Conçu dans une approche clinique, cet ouvrage constitue une introduction approfondie à la neurologie du comportement. Après un rappel des bases anatomiques du cerveau, chaque chapitre traite successivement des principaux troubles : • État confusionnel et troubles de l'attention • Syndromes frontaux • Aphasies et syndromes apparentés • Troubles du traitement spatial • Agnosies • Troubles mnésiques • Syndromes calleux • Démences Ces troubles sont d'abord définis, puis passés au crible de l'analyse anatomoclinique afin d'en examiner les causes et l'évolution. Pour chacune de ces pathologies, les techniques d'évaluation sont détaillées en fonction du contexte clinique. Aussi, cet ouvrage présente un réel intérêt pratique et pédagogique à travers l'étude de nombreux cas cliniques, des propositions de tests adaptés, et de multiples schémas anatomiques et tableaux récapitulatifs.

  • Cytokines and the Brain

    • 1st Edition
    • Volume 6
    • English
    This book opens a new page of neuro-immunobiology providing substantive experimental and clinical data to support current understanding in the field, and potential applications of this knowledge in the treatment of disease. The volume is a collection of complex, new data drawn from multiple areas of investigation in the field. The contents summarize current understanding on the presence and function of CNS cytokines and their receptors in a variety of CNS cells during health and disease. The chapters are a collection of complex, new data demonstrating the presence and synthesis of cytokines in brain cells, as well as their receptors on cell membranes in health and disease. The strength of the volume are the descriptions of the authors own investigations, together with those of others in the field pertaining to a large number of cytokines in brain function, as well as mechanisms involved in the development of CNS disorders, including multiple sclerosis and Alzheimer’s disease. Also included are novel approaches to the treatment of CNS disorders based on new experimental data. The contributors to this volume are internationally known scientists and clinical researchers in their respective fields of investigation and treatment.

  • Essence of Memory

    • 1st Edition
    • Volume 169
    • Wayne S. Sossin + 3 more
    • English
    This selection of reviews gives an up-to-date picture of memory research. Great progress has been made in identifying the memory trace at the molecular and cellular level and individual reviews address the major mechanisms by which changes in synaptic strength can persist. Exciting research at the systems level is also reviewed including the growing importance of changes in inhibitory interneurons and how they play a role in memory formation. Finally, reviews present cognitive and neurobiological models of human memory that explain, characterize and organize the act of memory within a coherent framework.

  • Atlas of the Developing Rat Nervous System

    • 3rd Edition
    • Ken Ashwell
    • English
    The Atlas of the Developing Rat Nervous System, 3rd edition builds on the many excellent features of the second edition by increasing the number of ages represented and by the inclusion of colour plates. The third edition now contains over 20% more plates with the added material depicting early ages not well covered in earlier editions and yet is presented in a concise easy-to-use format. The Atlas provide the most comprehensive depiction not just of structures in the brain and spinal cord but also of peripheral nervous system elements and their target organs that are important for developmental neurobiologists. This allows the user to follow seamlessly neural structures through the developing embryo in both time and space. The nomenclature and identification of structures in the third edition has been thoroughly updated to ensure accuracy and compatibility with modern developmental biology findings and terminology.

  • The Limits of Dream

    A Scientific Exploration of the Mind / Brain Interface
    • 1st Edition
    • J. F. Pagel
    • English
    Approx.250 pages

  • Handbook of the Neuroscience of Language

    • 1st Edition
    • Brigitte Stemmer + 1 more
    • English
    In the last ten years the neuroscience of language has matured as a field. Ten years ago, neuroimaging was just being explored for neurolinguistic questions, whereas today it constitutes a routine component. At the same time there have been significant developments in linguistic and psychological theory that speak to the neuroscience of language. This book consolidates those advances into a single reference. The Handbook of the Neuroscience of Language provides a comprehensive overview of this field. Divided into five sections, section one discusses methods and techniques including clinical assessment approaches, methods of mapping the human brain, and a theoretical framework for interpreting the multiple levels of neural organization that contribute to language comprehension. Section two discusses the impact imaging techniques (PET, fMRI, ERPs, electrical stimulation of language cortex, TMS) have made to language research. Section three discusses experimental approaches to the field, including disorders at different language levels in reading as well as writing and number processing. Additionally, chapters here present computational models, discuss the role of mirror systems for language, and cover brain lateralization with respect to language. Part four focuses on language in special populations, in various disease processes, and in developmental disorders. The book ends with a listing of resources in the neuroscience of language and a glossary of items and concepts to help the novice become acquainted with the field. Editors Stemmer & Whitaker prepared this book to reflect recent developments in neurolinguistics, moving the book squarely into the cognitive neuroscience of language and capturing the developments in the field over the past 7 years.

  • Learning and Memory: A Comprehensive Reference

    • 1st Edition
    • John H. Byrne
    • English
    The study of Learning and Memory is a central topic in Neuroscience and Psychology. It is also a very good example of a field that has come into maturity on all levels - in the protein chemistry and molecular biology of the cellular events underlying learning and memory, the properties and functions of neuronal networks, the psychology and behavioural neuroscience of learning and memory. Many of the basic research findings are directly applicable in the treatment of diseases and aging phenomena, and have found their way into educational theory and praxis. Learning and Memory: A Comprehensive Reference is the most comprehensive source of information about learning and memory ever assembled, and the definitive reference work on the topic. In four volumes, Editor-in-Chief John H. Byrne (University of Texas), together with volume editors Howard Eichenbaum (Boston University) for Systems and Neuroscience, Randolf Menzel (Freie Universität Berlin) for Behavioral Approaches, Henry Roediger (Washington University) for Cognitive Psychology, and David Sweatt (University of Alabama, Birmingham) for Molecular Mechanisms, have put together a truly authoritative collection of overview articles in 159 chapters on over 3000 pages. Learning and Memory: A Comprehensive Reference presents an extensive, integrated summary of the present state of research in the neurobiology and psychology of learning and memory and covers an enormous range of intellectual territory. With topics ranging from the neurochemistry and neurobiology of learning at the cellular and synaptic levels, systems neurobiology, the study of remarkable capabilities in animals (such as homing), ethological and behavioristic analyses, mechanisms, psychology, and disorders of learning and memory in humans, the work broadly covers all topics in the neurobiology and psychology of learning and memory. There is no other handbook with such a comprehensive coverage and depth. The authors selected are the leading scholars for the particular topics on which they write.

  • The Mouse Brain in Stereotaxic Coordinates, Compact

    The Coronal Plates and Diagrams
    • 3rd Edition
    • Keith B.J. Franklin + 1 more
    • English
    The Mouse Brain in Stereotaxic Coordinates is the most widely used and cited atlas of the mouse brain in print. It provides researchers and students with both accurate stereotaxic coordinates for laboratory use, and detailed delineations and indexing of structures for reference. The Compact 3rd edition is both a major revision and an expansion of previous compact editions. The 100 high resolution digital photographs of the coronal plane of section from the third full edition now complement the coronal drawings. The photographs of the sections and the intermediate sections are also provided on the accompanying CD. In addition, the compact version has a large introduction on stereotaxic surgery and the use of the atlas in the lab, as well as a number of panoramic simplified diagrams for student instruction. The Compact 3rd edition is in 8.5 x 11 format and is spiral bound suitable for positioning next to microscopes and cryotomes.

  • Handbook of Anxiety and Fear

    • 1st Edition
    • Volume 17
    • D. Caroline Blanchard + 2 more
    • English
    This Handbook brings together and integrates comprehensively the core approaches to fear and anxiety. Its four sections: Animal models; neural systems; pharmacology; and clinical approaches, provide a range of perspectives that interact to produce new light on these important and sometimes dysfunctional emotions. Fear and anxiety are analyzed as patterns that have evolved on the basis of their adaptive functioning in response to threat. These patterns are stringently selected, providing a close fit with environmental situations and events; they are highly conservative across mammalian species, producing important similarities, along with some systematic differences, in their human expression in comparison to that of nonhuman mammals. These patterns are described, with attention to both adaptive and maladaptive components, and related to new understanding of neuroanatomic, neurotransmitter, and genetic mechanisms. Although chapters in the volume acknowledge important differences in views of fear and anxiety stemming from animal vs. human research, the emphasis of the volume is on a search for an integrated view that will facilitate the use of animal models of anxiety to predict drug response in people; on new technologies that will enable direct evaluation of biological mechanisms in anxiety disorders; and on strengthening the analysis of anxiety disorders as biological phenomena.

  • Computational Neuroscience in Epilepsy

    • 1st Edition
    • Ivan Soltesz + 1 more
    • English
    Epilepsy is a neurological disorder that affects millions of patients worldwide and arises from the concurrent action of multiple pathophysiological processes. The power of mathematical analysis and computational modeling is increasingly utilized in basic and clinical epilepsy research to better understand the relative importance of the multi-faceted, seizure-related changes taking place in the brain during an epileptic seizure. This groundbreaking book is designed to synthesize the current ideas and future directions of the emerging discipline of computational epilepsy research. Chapters address relevant basic questions (e.g., neuronal gain control) as well as long-standing, critically important clinical challenges (e.g., seizure prediction). Computational Neuroscience in Epilepsy should be of high interest to a wide range of readers, including undergraduate and graduate students, postdoctoral fellows and faculty working in the fields of basic or clinical neuroscience, epilepsy research, computational modeling and bioengineering.

  • Fundamental Neuroscience

    • 3rd Edition
    • Larry Squire + 6 more
    • English
    Fundamental Neuroscience, Third Edition introduces graduate and upper-level undergraduate students to the full range of contemporary neuroscience. Addressing instructor and student feedback on the previous edition, all of the chapters are rewritten to make this book more concise and student-friendly than ever before. Each chapter is once again heavily illustrated and provides clinical boxes describing experiments, disorders, and methodological approaches and concepts.Capturing the promise and excitement of this fast-moving field, Fundamental Neuroscience, 3rd Edition is the text that students will be able to reference throughout their neuroscience careers!

  • Cellular and Molecular Neurophysiology

    • 3rd Edition
    • Constance Hammond
    • English
    Cellular and Molecular Neurophysiology, Third Edition, is the new, thoroughly revised edition of the only current, established, and authoritative text focusing on the cellular and molecular physiology of nerve cells. Previously titled Cellular and Molecular Neurobiology, the new title better reflects this focus. This version contains 80% new or updated material. Fifteen appendices describing neurobiological techniques are interspersed in the text. Now in full color throughout, the book has over 400 carefully selected and constructed illustrations. It includes an instructor website with all the images in electronic format, plus additional material. The book is hypothesis driven rather than just presenting the facts, and the content is firmly based on numerous experiments performed by the top experts in the field. While covering the important facts, the book also presents the background for how researchers arrived at this knowledge to provide a context for the field. It promotes a real understanding of the function of nerve cells that is useful for practicing neurophysiologists and students in a graduate-level course on the topic alike.

  • CNS Regeneration

    Basic Science and Clinical Advances
    • 2nd Edition
    • Jeffrey Kordower + 1 more
    • English
    This second edition of CNS Regeneration updates the burgeoning field of regeneration in the Central Nervous System (CNS) from molecular, systems, and disease-based perspective. While the book covers numerous areas in detail, special emphasis is given to discussions of movement disorders such as Parkinson’s disease, Alzheimer’s disease, and spinal cord injury.

  • The Senses: A Comprehensive Reference

    • 1st Edition
    • Allan I. Basbaum + 3 more
    • English
    This major new publishing event provides the first up-to-date, cutting-edge, comprehensive reference work combining volumes on all major sensory modalities in one set in three decades. Under the guidance of a distinguished team of international experts, 6 volumes collected 300 articles from all the top scientists laying out our current knowledge on the anatomy, physiology, and molecular biology of sensory organs. Topics covered include the perception, psychophysics, and higher order processing of sensory information, as well as disorders and new diagnostic and treatment methods. Written for a wide audience, this reference work provides students, scholars, medical doctors, and anyone interested in neuroscience a comprehensive overview of the knowledge accumulated on the function of sense organs, sensory systems, and how the brain processes sensory input. Leading scholars from around the world contributed articles, making The Senses a truly international portrait of sensory physiology. The set is the definitive reference on sensory neuroscience on the market, and will provide the ultimate entry point into the review and original literature in Sensory Neuroscience, and be a natural place for interested students and scientists to deepen their knowledge.

  • Ocular Therapeutics

    Eye on New Discoveries
    • 1st Edition
    • Thomas Yorio + 2 more
    • English
    Ocular Therapeutics: Eye on New Discovery focuses on emerging areas in ocular research, from new approaches to dry eye to gene therapy in the management of retinal diseases. This comprehensive book features more than 25 chapters of information that will be vital for ocular investigators and ophthalmologists bringing them new information on promising therapeutics. It is the intent of this book to provide not only information on current approaches to treatment, but also in giving the reader a greater understanding as to what may become available for treating a number of important eye diseases. Each chapter features some new aspect of treatment that holds great promise for the future. The approach has been to concentrate on those areas of ocular diseases that are more prevalent. It also features new insight for drug delivery and for managing devasting diseases, such as macula edema and glaucoma, two of the leading causes of blindness in the United States. This book will serve as an important resource as it contains a number of relevant references highlighted for their importance to the field. New investigators will be able to obtain an historical perspective for each of the topics and to develop an understanding of the new research directions that are underway. Ocular Therapeutics: Eye on New Discovery is more than a reference book, as it also provides an important glimpse into the near future.

  • Atlas of the Human Brain

    • 3rd Edition
    • Juergen K Mai + 2 more
    • English
    High-resolution human imaging requires a high-resolution atlas. There is no atlas that approaches the accuracy and comprehensiveness of The Atlas of the Human Brain. This is the third, thoroughly revised, edition of the very successful atlas that received the Award of Excellence from the American Association of Publishers. Constructed by the recognized leaders in brain cartography, the atlas provides the most detailed and accurate delineations of brain structure available. It is intended as an atlas for day-to-day use in the research laboratory to identify macroscopic and microscopic structures in the human brain as collected in research data with a variety of methods. It will also be particularly useful for the interpretation of magnetic resonance imaging data. The atlas includes a DVD with not only the atlas in electronic format, providing electronic versions of drawings and photographs to facilitate use of atlas contents with researchers' own material, but also 3D visualisation software that allows easy browsing of the images, and a feature to allow direct retrieval of brain areas using coordinates obtained in magnetic resonance imaging.

  • Handbook of Neuro-Oncology Neuroimaging

    • 1st Edition
    • Ferenc A. Jolesz + 1 more
    • English
    Although the field of Neuro-Oncology has grown considerably in the last 10 to 15 years and has a rather extensive literature, there are no comprehensive, “single-source” books that summarize the current literature and future trends of neuroimaging in neuro-oncology. This book covers this topic in more comprehensive fashion, making it an important addition to the armamentarium of physicians that care for patients with brain tumors and other neuro-oncological disorders. Well-founded in basic science, it includes chapters that provide an overview of relevant background material in critical areas such as physics, contrast agents, ultra-high field brain MRI, and molecular imaging.

  • Psychophysiological States

    The Ultradian Dynamics of Mind-Body Interactions
    • 1st Edition
    • Volume 80
    • David S. Shannahoff-Khalsa
    • English
    Our understanding of psychophysiological states are now more broadly defined by the inclusion of the lateralized ultradian rhythms of the autonomic and central nervous systems (ANS and CNS) that play a key regulatory role in mind-body states. These neural rhythms are a unique step in the evolution of the nervous system that have mostly been ignored or missed in our understanding of physiology, mental activities, brain rhythms, and in the treatment of psychiatric disorders. The multivariate physiological experiments reviewed in this book provide a new “big picture” for how the body’s major systems (ANS, CNS, neuroendocrine, cardiovascular, fuel-regulatory, gastrointestinal, immune) are regulated, integrated, and coordinated by the ANS via the hypothalamus during both waking and sleep. This discovery has implications for psychiatrists, psychologists, stress physiologists, cardiologists, sleep researchers, neuroscientists, neuroendocrinologist... cognitive scientists, and those interested in performance, anxiety, depression, schizophrenia, autism, and addictive and impulse control disorders. This book includes the translational neuroscience aspect of this discovery, including implications for vagal nerve stimulation studies.

  • Advances in the Study of Behavior

    • 1st Edition
    • Volume 37
    • H. Jane Brockmann + 5 more
    • English
    Advances in the Study of Behavior was initiated over 40 years ago to serve the increasing number of scientists engaged in the study of animal behavior. That number is still expanding. This volume makes another important "contribution to the development of the field" by presenting theoretical ideas and research to those studying animal behavior and to their colleagues in neighboring fields. This volume reflects many of the current themes in animal behavior including the evolution of social behavior, sexual selection and communication. It also reflects controversial topics on which the authors provide interesting, new insights. Advances in the Study of Behavior is now available online at ScienceDirect — full-text online from volume 30 onwards.

  • Computational Neuroscience: Theoretical Insights into Brain Function

    • 1st Edition
    • Volume 165
    • Paul Cisek + 2 more
    • English
    Computational neuroscience is a relatively new but rapidly expanding area of research which is becoming increasingly influential in shaping the way scientists think about the brain. Computational approaches have been applied at all levels of analysis, from detailed models of single-channel function, transmembrane currents, single-cell electrical activity, and neural signaling to broad theories of sensory perception, memory, and cognition. This book provides a snapshot of this exciting new field by bringing together chapters on a diversity of topics from some of its most important contributors. This includes chapters on neural coding in single cells, in small networks, and across the entire cerebral cortex, visual processing from the retina to object recognition, neural processing of auditory, vestibular, and electromagnetic stimuli, pattern generation, voluntary movement and posture, motor learning, decision-making and cognition, and algorithms for pattern recognition. Each chapter provides a bridge between a body of data on neural function and a mathematical approach used to interpret and explain that data. These contributions demonstrate how computational approaches have become an essential tool which is integral in many aspects of brain science, from the interpretation of data to the design of new experiments, and to the growth of our understanding of neural function.

  • The Psychology of Learning and Motivation

    Skill and Strategy in Memory Use
    • 1st Edition
    • Volume 48
    • English
    The view of memory use as skilled performance embraces the interactive nature of memory and higher order cognition. In considering the contexts in which memory is used, this book helps to answer such questions as: If asked where I live, how do I decide on a street address or city name? What influences my selection in a criminal lineup besides actual memory of the perpetrator? Why do expert golfers better remember courses they've played than amateur golfers? Chapters in this volume discuss strategies people use in responding to memory queries- whether and how to access memory and how to translate retrieved products into responses. Coverage includes memory for ongoing events and memory for prospective events-how we remember to do future intended actions. Individual differences in memory skill is explored across people and situations, with special consideration given to the elderly population and how strategies at encoding and retrieval can offset what would otherwise be declining memory.

  • The Evolution of Hemispheric Specialization in Primates

    • 1st Edition
    • Volume 5
    • William D. Hopkins
    • English
    Hemispheric specialization, and lateralized sensory, cognitive or motor function of the left and right halves of the brain, commonly manifests in humans as right-handedness and left hemisphere specialization of language functions. Historically, this has been considered a hallmark of, and unique to, human evolution. Some theories propose that human right-handedness evolved in the context of language and speech while others that it was a product of the increasing motor demands associated with feeding or tool-use. In the past 20-25 years, there has been a plethora of research in animals on the topic of whether population-level asymmetries in behavioral processes or neuro-anatomical structures exist in animals, notably primates and people have begun to question the historical assumptions that hemispheric specialization is unique to humans. This book brings together various summary chapters on the expression of behavioral and neuro-anatomical asymmetries in primates. Several chapters summarize entire families of primates while others focus on genetic and non-genetic models of handedness in humans and how they can be tested in non-human primates. In addition, it makes explicit links between various theoretical models of the development of handedness in humans with the observed patterns of results in non-human primates. A second emphasis is on comparative studies of handedness in primates. There is now enough data in the literature across different species to present an evolutionary tree for the emergence of handedness (and perhaps other aspects of hemispheric specialization, such as neuro-anatomical asymmetries) and its relation to specific morphological and ecological adaptations in various primate species.

  • The Dentate Gyrus: A Comprehensive Guide to Structure, Function, and Clinical Implications

    • 1st Edition
    • Volume 163
    • Helen E. Scharfman
    • English
    The dentate gyrus is a part of the brain that has been a topic of intense interest since the beginning of neuroscience, and pioneering studies from the distant and recent past attest to this. One of the reasons for such interest is that this structure provides some of the most remarkable examples of plasticity within the nervous system. In addition, it is critical to normal cognitive function, although exactly how and when is still a question that eludes answers. Furthermore, abnormalities within the dentate gyrus appear to play a role in diverse clinical conditions, from depression to epilepsy and traumatic brain injury. The primary goal of this book is to provide a context, or background, upon which the detailed knowledge of the current era can be appreciated. A series of overviews are provided to clarify essentials related to structural organization and development, cellular components, neurotransmitters and neuromodulators, plasticity, and clinical relevance.

  • The Chick Brain in Stereotaxic Coordinates

    An Atlas featuring Neuromeric Subdivisions and Mammalian Homologies
    • 1st Edition
    • Luis Puelles + 4 more
    • English
    The chicken is the standard model for avian and vertebrate brain anatomy, particularly in development. The Chick Brain in Stereotaxic Coordinates contains 200 coronal plates and diagrams, 40 sagittal plates and diagrams, and 20 horizontal plates and diagrams, illustrated in stereotaxic coordinates. This book is essential for anyone studying the physiology and function of the chick brain.

  • HIV/AIDS and the Nervous System

    • 1st Edition
    • Volume 85
    • Peter Portegies + 1 more
    • English
    This volume provides a comprehensive understanding of HIV/AIDS and neuro-AIDS, including a history of the disease, and an explanation of many of the conditions that can arise in afflicted patients, including opportunistic infections, central nervous system tumors, spinal cord disorders, myopathies and progressive encephalopathy, amongst others. Clinicians will gain a greater understanding of the complex mechanisms of the disease. Beginning with a basic introduction to HIV infections and Neuro-AIDS, practitioners will find useful data on advances in molecular biology, neuroepidemiology, neuroimaging, neuropathology, neuropharmacology, as well as information on the development of therapeutic strategies appropriate for the disorder, including groundbreaking retroviral therapies. In addition, the socioeconomic and political constraints that hinder treatment and disease management in developing parts of the world are presented.

  • Myopathies and Muscle Diseases

    • 1st Edition
    • Volume 86
    • Frank L. Mastaglia + 1 more
    • English
    This volume provides a comprehensive guide to myopathies, including breakthroughs that have led to a wider appreciation of the nature of these muscle diseases. Chapters on congenital muscle disorders, biological changes, and diseases associated with aging are included, along with detailed discussions of mitochondrial myopathies, disorders of carbohydrate and lipid metabolism, and the role of heredity, amongst others. Neurologists, myopathologists, and other professionals dealing with this broad group of diseases will find state-of-the-art information on the clinical investigation and management of patient care, as well as the latest information on the pathological basis and molecular pathogenesis of these diseases.

  • Parkinson's Disease and Related Disorders, Part II

    • 1st Edition
    • Volume 84
    • William C. Koller + 1 more
    • English
    This volume provides comprehensive information on Parkinson’s disease and related disorders, a group of diseases that are among the most common in the field of neurodegenerative study. Through a high-level presentation of new research regarding these diseases, this handbook will give clinicians and neuroscientists alike a better understanding of the dramatic pharmacological advances made in the management of Parkinson’s disease, and the profound observations that have altered the medical community’s approach to other degenerative disorders of the nervous system. Practitioners, researchers, and medical personnel will gain exciting insights into recent developments that form the basis for new therapeutic strategies and management protocols for the various neurological disorders that present with Parkinsonism.

  • Trisomie et handicaps génétiques associés

    Potentialités, compétences, devenir
    • 5th Edition
    • French
    Destiné aux professionnels de santé médicaux et paramédicaux, cet ouvrage aborde de manière concrète et pragmatique tous les aspects de la prise en charge d'un patient atteint de trisomie ou d'un handicap génétique associé. Avec une symptomatologie actualisée, un suivi médical étape par étape et des conseils validés, le lecteur trouvera ici un outil indispensable et à jour pour le suivi de son patient et pour apporter toute l'aide nécessaire à la famille. L'auteur a particulièrement développé dans ce nouvel ouvrage tous les aspects pratiques de l'aide à apporter aux patients atteints de trisomies pour améliorer leur qualité de vie ainsi que des réponses précises aux questions que se posent les parents tout au long des étapes de vie de l'enfant et de la personne concernée (prise en charge précoce, scolarisation, développement affectif et sexuel, activités sportives, relations avec les adolescents et la fratrie, formation professionnelle, loisirs, tabac, alcool, liberté de déplacement, permis de conduire, relation avec l'argent, protection juridique, revenus, habitat, vie en couple, contraception, vieillissement …). En réponse à une forte demande, cet ouvrage, 5e édition totalement renouvelée, étudie notamment la prise en charge des oro praxies, le vieillissement et introduit la notion nouvelle de « périodes phares ou charnières » qui déterminent l'avenir du patient atteint de trisomie.

  • The Neurobiology of Multiple Sclerosis

    • 1st Edition
    • Volume 79
    • English
    Multiple sclerosis (MS) is an immune-mediated neurodegenerative disorder of the human central nervous system (CNS) which usually affects young adults with certain genetic backgrounds who are then exposed to certain precipitating environmental antigen(s). Despite major advances of the past two decades in understanding the pathophysiology of MS, and in spite of the introduction of new immunomodulatory and immuno-suppressive agents which may slow down disease progression and delay the onset of disability, the “cause” and the “cure” for MS remain elusive. This volume of International Review of Neurobiology focuses on MS and related disorders. The volume can be divided into various sections with the main emphasis on MS pathogenesis, clinical features and epidemiology, neuroimaging, and treatment. The ultimate goal of this book is to encourage further research into the pathogenesis of this elusive disease.

  • Functional and Dysfunctional Sexual Behavior

    A Synthesis of Neuroscience and Comparative Psychology
    • 1st Edition
    • Anders Ågmo
    • English
    Functional and Dysfunctional Sexual Behavior explores the full consequences of the dissociation between sexual behaviors and reproduction. Among the themes covered is the difference between the stereotyped sexual behaviors in non-human mammals and the astounding variety of human sexual behaviors. The role of learning in shaping sexual behaviors is explained, and it is shown how particular sexual experiences may be at the origin of common human sexual dysfunctions. Chapters on sexual incentives and a summary of the endocrine and central nervous control of sexual behaviors are included.

  • Cognition, Brain, and Consciousness

    Introduction to Cognitive Neuroscience
    • 1st Edition
    • Bernard J. Baars + 1 more
    • Bernard J. Baars + 1 more
    • English
    A textbook for psychology, neuroscience, pre-medical students, and everybody interested in the neuroscience of cognition. A wave of new research is transforming our understanding of the human mind and brain. Many educational fields now require a basic understanding of the new topic of cognitive neuroscience. However, available textbooks are written more for biology audiences than for psychology and related majors. This text aims to bridge that gap. A background in biology of neuroscience is not required. The thematic approach builds on widely understood concepts in psychology, such as working memory, selective attention, and social cognition. Edited by two leading experts in the field, the book guides the reader along a clear path to understand the latest findings. FEATURES: Written specifically for psychology, pre-medical, education and neuroscience undergraduate and graduate students The thematic approach builds on on accepted concepts, not presuming a background in neuroscience or biology Includes two Appendices on brain imaging and neural networks written by Thomas Ramsoy and Igor Aleksander Introduces the brain in a step-by-step, readable style, with gradually increasing sophistication Richly illustrated in full color with clear and detailed drawings that build the brain from top to bottome, simplifying the layout of the brain for students Pedagogy includes exercises and study questions at the end of each chapter

  • Neurobiology of Learning and Memory

    • 2nd Edition
    • Raymond P. Kesner + 1 more
    • English
    The first edition of Neurobiology of Learning and Memory was published in 1998 to rave reviews. As before, this second edition will discuss anatomy, development, systems, and models though the organization and content is substantially changed reflecting advances in the field. Including information from both animal and human studies, this book represents an up-to-date review of the most important concepts associated with the basic mechanism that support learning and memory, theoretical developments, use of computational models, and application to real world problems. The emphasis of each chapter will be the presentation of cutting-edge research on the topic, the development of a theoretical perspective, and providing an outline that will aid a student in understanding the most important concepts presented in the chapter.

  • Eye Movements

    A Window on Mind and Brain
    • 1st Edition
    • Roger PG van Gompel
    • English
    Eye-movement recording has become the method of choice in a wide variety of disciplines investigating how the mind and brain work. This volume brings together recent, high-quality eye-movement research from many different disciplines and, in doing so, presents a comprehensive overview of the state-of-the-art in eye-movement research. Sections include the history of eye-movement research, physiological and clinical studies of eye movements, transsaccadic integration, computational modelling of eye movements, reading, spoken language processing, attention and scene perception, and eye-movements in natural environments.

  • Manuel d'EEG de l'adulte

    Veille et sommeil
    • 1st Edition
    • Chantal Hausser-Hauw
    • French
    Quelle est la place, aujourd'hui, de l'électroencéphalogr... ? Non invasif et peu coûteux, l'EEG rend compte de l'activité électrique cérébrale du patient à l'instant même où elle est enregistrée et apporte une analyse immédiate du fonctionnement correct du cerveau ou de son atteinte. Sa place dans l'étude du sommeil est primordiale. L'EEG nécessite un minimum de compréhension des principes physiques et des techniques d'enregistrement des rythmes cérébraux et du sommeil. Cet ouvrage a été conçu chapitre par chapitre pour familiariser le lecteur à l'intérêt de l'EEG dans le diagnostic des épilepsies, des complications neurologiques des maladies systémiques, des encéphalopathies, de l'éthylisme, de la grossesse et des effets médicamenteux, des traumatismes crâniens en phase aiguë et chronique. Le rôle médico-légal de l'EEG dans l'anoxie et la mort cérébrale et son aide dans le diagnostic des démences sont également détaillés. L'étude du sommeil des maladies dégénératives est particulièrement développée. Les maladies pour lesquelles l'EEG offre un supplément d'information par rapport à l'imagerie en cas de crises épileptiques, de confusion ou de troubles de la vigilance sont exposées. Une partie est consacrée à l'intérêt de l'EEG en psychiatrie. Enfin, l'ouvrage détaille l'usage de l'EEG lors d'événements transitoires comme la migraine, l'ictus amnésique, la plongée, la privation sensorielle et lors des états volontairement modifiés de la conscience (biofeedback, méditation, hypnose).

  • Handbook of Microdialysis

    Methods, Applications and Perspectives
    • 1st Edition
    • Volume 16
    • English
    Microdialysis is currently one of the most important in vivo sampling methods in physiology and pharmacology. It is used to determine the chemical components of the fluid in the extracellular space of tissues. The technique is now well established in neuroscience research and is used excessively in behavioral neuroscience to determine the concentrations and identities of molecules in brain tissues, and their change due to behavior, hormonal and transmitter changes in the nervous system. The book provides a detailed comprehensive overview of the technology and its applications, including application in pathology, drug development, and the application in the clinic. The authors are all well known researchers in Neuroscience and experts in the use of Microdialysis. Organized into two parts of seven sections, the Handbook of Microdialysis critically examines recent developments in the field through a variety of chapters written by an internationally acclaimed group of authors. It is the first comprehensive handbook covering the technology of Microdialysis and its applications in Neuroscience.

  • The Pharmacology of Neurogenesis and Neuroenhancement

    • 1st Edition
    • Volume 77
    • English
    Currently, few drugs are available for the effective treatment of neurodegenerative diseases and neurodevelopmental disorders. Recent advances in neuroscience research offer hope that future strategies for treating these brain disorders will include neurogenesis and neuroenhancement as therapeutic endpoints. This volume reviews cutting-edge findings related to the pharmacological aspects of neurogenesis and neuroprotection. A broad range of topics are covered from basic lab bench research to drug discovery efforts and important clinical issues. This collection of reviews is a perfect way to become acquainted with these exciting new fields in the space of a single volume. Chapters are written with a general audience in mind, but with enough high-level discussion to appeal to specialists and experts as well. The authors have done an excellent job of challenging current paradigms and pushing the boundaries of exploration in keeping with the pioneering spirit that gave rise to these emerging areas of research. Consequently, this will be an indispensable resource for many years to come.

  • Appetite and Body Weight

    Integrative Systems and the Development of Anti-Obesity Drugs
    • 1st Edition
    • Tim Kirkham + 1 more
    • English
    There is now enough basic work to sketch out the principal systems at all levels of the brain, from prefrontal cortex to lower brainstem, which are orchestrated to provide control of food selection, preference and consumption. At the same time, the complex interplay between central systems and signals generated from peripheral systems include the gut, liver and fat stores, as well as the interactions with the neuroendocrine system can be described in some detail. A continuing theme throughout the book is that the functional analysis of appetite and food intake cannot be limited to a single focus, e.g. hypothalamic neuropeptides and their interactions, but must be based on a fully integrated view of the several contributing systems. Appetite and Body Weight: Integrative Systems and the Development of Anti-Obesity Drugs provides an expert guide to the neural, neurochemical, autonomic and endocrine interrelations which underpin appetite and the controls of food intake and body weight. The book covers many of the neurochemical entities that are currently under investigation, including: neuropeptides, leptin, insulin, monoamines and endogenous cannabinoids in relation to appetite and body-weight control. In addition to the neuroscience analysis, there are also chapters that provide an expert guide to some of the key psychological concepts that the researchers believe are essential in trying to understand the phenomena under investigation. The volume will also serve as an authoritative guide to the current emphasis on the development of novel, efficacious anti-obesity medication.

  • Research Funding in Neuroscience

    A Profile of the McKnight Endowment Fund
    • 1st Edition
    • Gabrielle Strobel
    • Sylvia Lindman
    • English
    The book is a history of the McKnight Endowment Fund for Neuroscience and an assessment of its effectiveness in advancing neuroscience. The book discusses the Fund's early and steady commitment to basic science as well as it's tradition of leveraging relatively modest dollars to make a big difference in careers and the field overall. The fund exists strictly to give awards and create a community of peers through an annual conference dedicated to research. In near unison, scientists who have received awards say they were able to test a risky idea, get their career off the ground, or make a significant change in their career because of McKnight's flexible dollars. The book consists of three parts: (1) origins--including both the funder and the scientists who shaped the program; (2) a review of the science to show how McKnight awardees have advanced the field; and (3) 10 keys to success. We also have an interview with Julius Axelrod (one of the early advisors, done shortly before his death in 2004) and stories of how awardees used their McKnight grants, plus other information.

  • Signal Processing for Neuroscientists

    An Introduction to the Analysis of Physiological Signals
    • 1st Edition
    • Wim van Drongelen
    • English
    Signal Processing for Neuroscientists introduces analysis techniques primarily aimed at neuroscientists and biomedical engineering students with a reasonable but modest background in mathematics, physics, and computer programming. The focus of this text is on what can be considered the ‘golden trio’ in the signal processing field: averaging, Fourier analysis, and filtering. Techniques such as convolution, correlation, coherence, and wavelet analysis are considered in the context of time and frequency domain analysis. The whole spectrum of signal analysis is covered, ranging from data acquisition to data processing; and from the mathematical background of the analysis to the practical application of processing algorithms. Overall, the approach to the mathematics is informal with a focus on basic understanding of the methods and their interrelationships rather than detailed proofs or derivations. One of the principle goals is to provide the reader with the background required to understand the principles of commercially available analyses software, and to allow him/her to construct his/her own analysis tools in an environment such as MATLAB®.

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